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Topic Review
Fear Appeal Theory in Climate Change Communication
Although loss frames are strictly defined by their linguistic structure (i.e., conditional propositions with the structure “if not-then [undesired outcome]”) while fear appeals are more defined by their effects (i.e., the fear and perceived threat they elicit), the definitions of loss frames and fear appeals may largely be emphasizing different aspects of the same persuasive message, which may be understood with the same theory. If correct, fear appeal theory may offer an established and well-evidenced framework to guide goal-framing research and explain goal-framing effects in the sustainability domain.
  • 1.8K
  • 04 Jul 2022
Topic Review
Implications of New Psychoactive Substances in Public Health
New psychoactive substances (NPS) aim to imitate the classical and controlled drugs, such as cannabis, cocaine, heroin, lysergic acid diethylamide (LSD), or methamphetamine. For this reason, they can be divided and classified into different categories or categorized according to their psychotropic effects or nature
  • 1.8K
  • 13 May 2022
Topic Review
Haridasa
The Haridasa devotional movement originated in Karnataka, India, after Madhvacharya, and spread to eastern states such as Bengal and Assam of medieval India. Over a span of nearly six centuries, several saints and mystics helped shape the culture, philosophy and art of South India in general and Karnataka in particular by exerting considerable spiritual influence over the masses and kingdoms that ruled South India. This movement was ushered in by the Haridasas (lit "servants of Lord Hari") and took shape in the 13th century – 14th century CE period, prior to and during the early rule of the Vijayanagara empire. The main objective of this movement was to propagate the Dvaita philosophy of Madhvacharya (Madhva Siddhanta) to the masses through a literary medium known as Dasa Sahitya (lit "literature of the servants of the lord"). Prominent Hindu philosophers, poets and scholars such as Sripadaraya, Vyasathirtha, Vadirajatirtha, Purandara Dasa and Kanaka Dasa played an important role during this time. Though the movement found its roots in the Kannada country and later spread to other parts of South India, it was a net result of earlier devotional movements such as the Veerashaiva movement (of Vachana literature in Kannada) of northern Karnataka led by Basavanna (12th century) and the Alvar saints of Tamil Nadu (10th century). Later, Vallabhacharya in Gujarat and Guru Chaitanya were influenced by the teachings of Madhvacharya. Chaitanya Mahaprabhu's devotees started the International Society for Krishna Consciousness (ISKCON) - known colloquially as the Hare Krishna Movement. The Haridasas were saints, some of whom were wandering bards, and considered themselves as slaves of their supreme lord - Hari. While the movement was mainly heralded by the Brahmins, it was a devotional one whose ideals and thoughts pervaded and received noteworthy contributions from all sections of society. The Haridasa movement can be considered as a part of a larger Bhakti movement whose devotional inspiration to the masses lasted over a millennium. The Haridasa movement made significant contribution to Kannada devotional literature.
  • 1.8K
  • 29 Nov 2022
Topic Review
Measure the Height of Mount Everest
Mount Everest is the highest mountain in the world. First, we should know where is Mt. Everest located on the plateau of Tibet map. It is on the border of Nepal and Tibet(the Autonomous Region of China). The determination of the height of Mount Everest(HME) is one of the focuses of the geodetic community. The shallow layer method (SLM) based on the definition of the geoid can determine the gravity field inside the shallow layer. The orthometric height of Mount Everest (HME) is calculated based on SLM, in which the key is to construct the shallow layer model. The top and bottom boundaries of the shallow layer model are the natural surface of the Earth and the surface at a certain depth below the reference geoid, respectively. 
  • 1.8K
  • 31 Jan 2024
Topic Review
Cerebral Asymmetry
Human functions and traits are linked to cerebral networks serving different emotional and cognitive control systems, some of which rely on hemispheric specialization and integration to promote adaptive goal-directed behavior. Among the neural systems discussed in this context are those underlying pro- and antisocial behaviors. The diverse functions and traits governing our social behavior have been associated with lateralized neural activity. However, as with other complex behaviors, specific hemispheric roles are difficult to elucidate. This is due largely to environmental and contextual influences, which interact with neural substrates in the development and expression of pro and antisocial functions. This paper will discuss the reciprocal ties between environmental factors and hemispheric functioning in the context of antisocial behavior. The paper will attempt to familiarize readers with the prominent literature and primary questions to encourage further research and in-depth discussion in this field.
  • 1.8K
  • 22 Oct 2020
Topic Review
Irosustat: Clinical Steroid Sulfatase Inhibitor
Irosustat: (6-oxo-8,9,10,11-tetrahydro-7H-cyclohepta[c]chromen-3-yl) sulfamate; 6-oxo-8,9,10,11-tetrahydro-7H-cyclohepta-(c)(1)benzopyran-3-O-sulfamate; also known as STX64, 667 Coumate, BN83495, Oristusane is a tricyclic synthetic clinical drug of the aryl sulfamate ester class, designed mainly for applications in oncology as a steroid sulfatase inhibitor and has shown clinical benefit in patients.
  • 1.8K
  • 09 Feb 2021
Topic Review
Domestication in the Neotropics
Charles Darwin used domestication as a metaphor for natural selection because everyone is familiar with the term. Since Darwin, domestication has become a major topic of research, both to help understand evolution, as Darwin did, and to understand how human societies came to dominate the world, which also interested Darwin. However, Darwin did not define the term, which has allowed students of domestication, such as geneticists, archaeologists and others, to tailor their definitions to their own objectives. Even our grammar influences the way we interpret simple phrases about domestication ( p. xiv), as we tend to put ourselves, as individuals or the human collective, in charge. As Darwin pointed out, however, the long history of human interaction with plants and animals that resulted in the domestication of some of them was influenced more by unconscious selection than conscious selection. Only when considering the latter type of selection, which Darwin called methodical selection, can we affirm that humans are in charge, and even then unintended consequences are common. Nonetheless, especially when used in studies to understand how humans came to dominate the world, definitions often assume that humans are in control, which is unlikely at the beginning of human interactions with plants and animals. As pointed out by Dolores Piperno and Deborah Pearsall ( p. 6), clear definitions of concepts are extremely important when discussing domestication and the food production systems in which many domesticates are grown or raised. Melinda Zeder reviewed a set of definitions to highlight their differences and theoretical frameworks, and emphasized that definitions for plants and animals are often quite different. Clement et al. prepared a short list of definitions for plant domestication since Zeder. Full definitions can help identify nuances that place human culture within Nature, as occurs in most Neotropical ontologies, rather than outside, which is typical of ideas of being in charge. We think that returning to a dictionary is also an appropriate exercise to explore definitions, especially as the definitions in Zeder and Clement et al. were designed by their authors to meet their own objectives, the majority of which are associated with identifying changes in morphology or genetics that prove that human selection resulted in a response. We will use the 1989 edition of the Oxford English Dictionary (OED), whose first edition was being researched and published at the same time that Darwin was writing. The verb domesticate comes from the Latin domesticäre – to dwell in a house, to accustom. The house is the center of the domus, the Latin root of domesticäre. The OED definitions include: “1.a. To make, or settle as, a member of a household; to cause to be at home; to naturalize. 1.b. To make to be or to feel ‘at home’; to familiarize. 2. To make domestic; to attach to home and its duties. 3. To accustom (an animal) to live under the care and near the habitations of man; to tame or bring under control; to civilize. 4. To live familiarly or at home (with); to take up one's abode.” It follows that the noun domestication is “the action of domesticating, or the condition of being domesticated” (OED), i.e., both the process itself and the results of the process. These definitions are about humans, who domesticate each other in their houses, with their associated gardens, orchards, pastures, woodlots, agroforests, and adjacent managed forests. Hence, the house and the surrounding landscape comprise the domus , until humans started living in cities or more recently in apartments. Animals are recognized in one of the definitions as being domesticated in the domus also, and it was Darwin who included plants. From these definitions, domestication is clearly anthropocentric, i.e., it is about us humans. Note that only one definition mentions control.  What are the human behaviors involved? Two are explicit in the definitions: care (of the occupants of the domus) and duty (the tasks of caring for the domus and its occupants). Two are implicit. Selection – since humans are selective about what is brought into the domus. The fact that selection is implicit, rather than explicit, may be why Darwin adopted domestication as his metaphor for natural selection. Accumulation – as people and animals are brought into the domus, both from nearby (familiarize) and far away (naturalize). As Darwin recognized, humans like variety, which can be seen in most gardens and even more clearly in swiddens. The definitions above are about both organisms (humans, animals, plants) and the domus. Most current definitions of domestication concentrate one behavior (selection), but care and accumulation are just as important.
  • 1.8K
  • 04 Mar 2021
Topic Review
Review of Ionic Liquids Toxicity
Ionic liquids (more accurately room-temperature ionic liquids (RTILs)) can be defined as materials composed of organic or inorganic cations (like imidazolium or pyridinium) and anions (e.g., nitrate, acetate, tetrafluoroborate, dicyanamide, bis(trifluoromethylsulfonyl)imide and lactate) that are liquid at or below 100 °C. The number of possible combinations of a cation and anion is estimated to reach 106, making it theoretically possible to synthesize an IL targeted for a specific application or property.
  • 1.8K
  • 29 Jun 2021
Topic Review
SF1 Neurons
SF1 neurons in the ventromedial hypothalamus are a specific lead in the brain’s ability to sense glucose levels and conduct insulin and leptin signaling in energy expenditure and glucose homeostasis.
  • 1.8K
  • 22 Jun 2021
Topic Review
Green Tea Catechin EGCG-Sensing Receptor
The body is equipped with a “food factor-sensing system” that senses food factors, such as polyphenols, sulfur-containing compounds, and vitamins, taken into the body, and plays an essential role in manifesting their physiological effects. For example, (−)-epigallocatechin-3-O-gallate (EGCG), the representative catechin in green tea (Camellia sinensi L.), exerts various effects, including anti-cancer, anti-inflammatory, and anti-allergic effects, when sensed by the cell surficial protein 67-kDa laminin receptor (67LR). 
  • 1.8K
  • 19 Aug 2022
Topic Review
Semi-Closed Oxy–Fuel Combustion Power Cycles with CO2 Recirculation
With the increases in organic fuel prices and growing legislative restrictions aimed at increasing environmental safety and reducing the carbon footprint, the task of increasing thermal power plant efficiency is becoming more and more topical. Transforming combusting fuel thermal energy into electric power more efficiently will allow the reduction of the fuel cost fraction in the cost structure and decrease harmful emissions, especially greenhouse gases, as less fuel will be consumed. There are traditional ways of improving thermal power plant energy efficiency: increasing turbine inlet temperature and utilizing exhaust heat. An alternative way to improve energy efficiency is the use of supercritical CO2 power cycles, which have a number of advantages over traditional ones due to carbon dioxide’s thermophysical properties. In particular, the use of carbon dioxide allows increasing efficiency by reducing compression and friction losses in the wheel spaces of the turbines; in addition, it is known that CO2 turbomachinery has smaller dimensions compared to traditional steam and gas turbines of similar capacity.
  • 1.8K
  • 16 Dec 2022
Topic Review
Design and Synthesis of Sidechain Phosphorus-Containing Polyacids
Macromolecules containing acidic fragments in side-groups—polyacids—occupy a special place among synthetic polymers. Properties and applications of polyacids are directly related to the chemical structure of macromolecules: the nature of the acidic groups, polymer backbone, and spacers between the main chain and acidic groups. The chemical nature of the phosphorus results in the diversity of acidic >P(O)OH fragments in sidechain phosphorus-containing polyacids (PCPAs) that can be derivatives of phosphoric or phosphinic acids.
  • 1.8K
  • 13 Feb 2023
Topic Review
Cytochrome P450 in Escherichia coli
Cytochrome P450 (CYP) enzymes play important roles in metabolising endogenous and xenobiotic substances. Characterisations of human CYP proteins have been advanced with the rapid development of molecular technology that allows heterologous expression of human CYPs. Among several hosts, bacteria systems such as Escherichia coli (E. coli) have been widely used thanks to their ease of use, high level of protein yields, and affordable maintenance costs.
  • 1.8K
  • 23 Feb 2023
Topic Review
Magnesium and COVID-19
Magnesium is the fourth most common mineral in the human body and the second richest intracellular cation. This element is necessary for many physiological reactions, especially in the cardiovascular and respiratory systems. COVID-19 is an infectious disease caused by SARS-CoV-2. The majority of people who become ill as a result of COVID-19 have mild-to-moderate symptoms and recover without specific treatment. Moreover, there are people who develop severe forms of COVID-19, which require highly specialized medical assistance. Magnesium deficiency may play a role in the pathophysiology of infection with SARS-CoV-2. The primary manifestation of COVID-19 remains respiratory, but the virus can spread to other organs and tissues, complicating the clinical picture and culminating in multiorgan failure. The key mechanisms involved in the disease include direct viral cytotoxicity, endothelial dysfunction, and exaggerated release of inflammatory cytokines. 
  • 1.8K
  • 24 Feb 2023
Topic Review
State of the Art in Textile Waste Management
Textile waste constitutes a significant fraction of municipal solid waste sent to landfill or incinerated. Its innovative management is important to enhance sustainability and circularity.
  • 1.8K
  • 29 Dec 2023
Topic Review
Effect of Stressors on Honeybee Immunity
Honeybees are the most prevalent insect pollinator species; they pollinate a wide range of crops. Colony collapse disorder (CCD), which is caused by a variety of biotic and abiotic factors, incurs high economic/ecological loss. Various ecological stressors are microbial infections, exposure to pesticides, loss of habitat, and improper beekeeping practices that are claimed to cause these declines. Honeybees have an innate immune system, which includes physical barriers and cellular and humeral responses to defend against pathogens and parasites. Exposure to various stressors may affect this system and the health of individual bees and colonies.
  • 1.8K
  • 30 May 2022
Topic Review
Microbiota for HPV Infection
The microbiome is able to modulate immune responses, alter the physiology of the human organism, and increase the risk of viral infections and development of diseases such as cancer. Herein, we address changes in the cervical microbiota as potential biomarkers to identify the risk of cervical intraepithelial neoplasia (CIN) development and invasive cervical cancer in the context of human papillomavirus (HPV) infection.
  • 1.8K
  • 30 Oct 2020
Topic Review
COVID-19-Associated Candidiasis
The recent global pandemic of COVID-19 has predisposed a relatively high number of patients to acute respiratory distress syndrome (ARDS), which carries a risk to develop secondary infections. Candida species are major constituents of the human mycobiome and the main cause of invasive fungal infections with a high mortality rate, and are also increasingly reported as complication of severe COVID-19. Despite the marked immune dysregulation in COVID-19, no prominent defects have been reported in immune cells that are critically required for immunity to Candida. This suggests that relevant clinical factors, including prolonged ICU stays, use of central venous catheters and often broad-spectrum antibiotics may dominate over immune-mediated mechanisms to drive susceptibility to candidemia in the setting of COVID-19. Although diagnostic performance evaluations are often lacking in COVID-19 patients, a combination of serological and molecular techniques may present promising diagnostic options for identification of COVID-19-associated candidiasis. Clinical awareness and screening of invasive candidiasis is needed, as those are difficult to diagnose, particular in the setting of severe COVID-19. Echinocandins and azoles are the primary antifungal used to treat invasive candidiasis, yet therapeutic failures exerted by prominent nosocomial pathogens such as C. auris and C. glabrata calls for the development of new antifungal drugs with novel mechanisms of action.
  • 1.8K
  • 26 Oct 2020
Topic Review
Electric Noise Spectroscopy
Electric noise spectroscopy is a non-destructive and a very sensitive method for studying the dynamic behaviors of the charge carriers and the kinetic processes in several condensed matter systems, with no limitation on operating temperatures. This technique has been extensively used to investigate several perovskite compounds, manganese oxides (La1−xSrxMnO3, La0.7Ba0.3MnO3, and Pr0.7Ca0.3MnO3), and a double perovskite (Sr2FeMoO6), whose properties have recently attracted great attention.
  • 1.8K
  • 22 Jan 2021
Topic Review
High-Entropy Alloys
Microstructural phase evolution during melting and casting depends on the rate of cooling, the collective mobility of constituent elements, and binary constituent pairs. Parameters used in mechanical alloying and spark plasma sintering, the initial structure of binary alloy pairs, are some of the factors that influence phase evolution in powder-metallurgy-produced HEAs. Factors such as powder flowability, laser power, powder thickness and shape, scan spacing, and volumetric energy density (VED) all play important roles in determining the resulting microstructure in additive manufacturing technology. Large lattice distortion could hinder dislocation motion in HEAs, and this could influence the microstructure, especially at high temperatures, leading to improved mechanical properties in some HEAs. Mechanical properties of some HEAs can be influenced through solid solution hardening, precipitation hardening, grain boundary strengthening, and dislocation hardening. Despite the HEA system showing reliable potential engineering properties if commercialized, there is a need to examine the effects that processing routes have on the microstructure in relation to mechanical properties. 
  • 1.8K
  • 09 Jun 2021
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