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Topic Review
Panax ginseng CYP703
Cytochrome P450 (CYP) catalyzes a wide variety of monooxygenation reactions in plant primary and secondary metabolisms. Land plants contain CYP703, belonging to the CYP71 clan, which catalyzes the biochemical pathway of fatty acid hydroxylation, especially in male reproductive tissues. Korean/Asian ginseng (Panax ginseng Meyer) has been regarded as one of important medicinal plant for a long time, however the molecular mechanism is less known on its development.
  • 705
  • 07 Mar 2022
Topic Review
Vitamin D and Skeletal Muscle
Aging is associated with impairment in skeletal muscle mass and contractile function, predisposing to fat mass gain, insulin resistance and diabetes.  At cell and animal levels, that VitD treatments had positive effects on the development of muscle fibres in cells in culture, skeletal muscle force and hypertrophy. 
  • 703
  • 22 May 2021
Topic Review
Relationship between Environmental Factors and Virus-Induced Symptoms
Plant viruses, as obligate intracellular parasites, induce significant changes in the cellular physiology of host cells to facilitate their multiplication. These alterations often lead to the development of symptoms that interfere with normal growth and development, causing USD 60 billion worth of losses per year, worldwide, in both agricultural and horticultural crops. 
  • 703
  • 25 Aug 2023
Topic Review
Assessment of Brassicaceae Seeds Quality by X-ray Analysis
The seeds of cruciferous crops (Brassicaceae family) are high in fat oil (33–40%) and protein (25–36%). They are the main nutrients of the seed. 
  • 702
  • 11 Jan 2022
Topic Review
The Nero Lucano Pig Breed
The Nero Lucano (NL) pig is a black coat colored breed characterized by a remarkable ability to adapt to the difficult territory and climatic conditions of Basilicata region in Southern Italy.
  • 701
  • 13 May 2021
Topic Review
Soil by Grazing Sport Horses
Soil ingestion has been well documented for the majority of outside reared animals but not in horses. As soil can be a vector of environmental pollutants, such studies generally aim at controlling exposure to pollutant uptake in food producing animals.
  • 701
  • 05 Aug 2021
Topic Review
Genomic Interventions for Wheat Biofortification
Wheat is an essential constituent of cereal-based diets, and one of the most significant sources of calories. However, modern wheat varieties are low in proteins and minerals. Biofortification is a method for increasing the availability of essential elements in the edible portions of crops through agronomic or genetic and genomic interventions. Wheat biofortification, as a research topic, has become increasingly prevalent. 
  • 701
  • 09 Dec 2021
Topic Review
Potential of Flow Cytometric Approaches in Food Industry
Microbial contamination, including the carryover of infectious microbes, is a global public health concern. An alternative technique that serves as a powerful, rapid, and highly sensitive method for the specific and non-specific detection, monitoring, enumeration, and characterization of microorganisms is flow cytometry (FCM).
  • 701
  • 12 Jan 2022
Topic Review
Localized Proteasomal Degradation
The proteasome is responsible for selective degradation of most cellular proteins. Abundantly present in the cell, proteasomes not only diffuse in the cytoplasm and the nucleus but also associate with the chromatin, cytoskeleton, various membranes and membraneless organelles/condensates. How and why the proteasome gets to these specific subcellular compartments remains poorly understood, although increasing evidence supports the hypothesis that intracellular localization may have profound impacts on the activity, substrate accessibility and stability/integrity of the proteasome.
  • 701
  • 08 Feb 2022
Topic Review
Video Processing for Physical Characteristics of Fishes
Acquiring the morphological parameters of fish with the traditional method (depending on human and non-automatic factors) not only causes serious problems, such as disease transmission, mortality due to stress, and carelessness and error, but it is also time-consuming and has low efficiency. 
  • 701
  • 21 Jun 2023
Topic Review
Noninfectious Causes of Late Embryonic/Early Fetal Losses
Pregnancy loss at any developmental stage affects the reproductive efficiency of cattle both at the individual and herd levels. In dairy cows, negative effects on milk production along with the increased antibiotic usage associated with pregnancy loss can have dramatic consequences on herd economy. Pregnancy loss during late embryonic and early fetal development can affect up to 20% of animals within a dairy cattle herd, so regular screening and pregnancy maintenance protocols are mandatory as it is important to identify animals at risk of losing their pregnancy after its diagnosis.
  • 700
  • 18 Dec 2023
Topic Review
EVOO’s Flavor
Extra virgin olive oil (EVOO) is one of the most distinctive ingredients of the Mediterranean diet. EVOO can be defined as the oil obtained from the fruit of the olive tree (Olea europaea), using exclusively mechanical or physical procedures. To obtain an EVOO, olives cannot be treated with other procedures than washing, decanting, centrifugation, and filtration, thus excluding oils obtained with solvents or by re-esterification or oil mixing procedures.
  • 699
  • 09 Mar 2021
Topic Review
Armed CAR-T or Combination Therapy for Prostate Cancer
CAR-T cells are genetically engineered T cells that express a unique fusion receptor. The receptor is composed of an extracellular domain, a hinge region, a transmembrane domain, and an intracellular signal transduction region.
  • 699
  • 28 Feb 2022
Topic Review
Injury Identification during Turkey Husbandry
Injurious pecking against conspecifics is a serious problem in turkey husbandry. Bloody injuries act as a trigger mechanism to induce further pecking, and timely detection and intervention can prevent massive animal welfare impairments and costly losses. Thus, the overarching aim is to develop a camera-based system to monitor the flock and detect injuries using neural networks. In a preliminary study, images of turkeys were annotated by labelling potential injuries. These were used to train a network for injury detection.
  • 698
  • 22 Feb 2023
Topic Review
Treatment for Itch in Atopic Dermatitis
This entry briefly describes the recent drugs for the treatment of atopic itch.
  • 698
  • 25 Nov 2021
Topic Review
Okadaic Acid Depuration from the Cockle Cerastoderma edule
The cockle Cerastoderma edule is a commercially important species in many European Countries. It can accumulate okadaic acid (OA) and other toxins in its group, which makes it unsuitable for human consumption, producing harvesting bans to avoid intoxications. The duration of those bans depends in part on the depuration kinetics of the toxin in this species. In this work, this kinetics was studied by means of fitting different models to depuration data experimentally obtained, using naturally contaminated cockles. Cockles depurated OA faster than most other bivalve species studied. Models that include Michaelis-Menten kinetics describe the depuration better than those using a first order exponential decrease to describe the first (or the only) compartment. One-compartment models were not able to describe the final part of the depuration curve, in which OA was depurated very slowly. Therefore, two-compartment models were needed. Esters were depurated at a much faster rate than the free form of the toxin; however, no significant esterification was detected during the process. The slow depuration rate suggests that other bivalve species could be used as sentinels to monitor cockle populations, but caution should be taken when toxin concentrations are very high. 
  • 697
  • 22 Mar 2022
Topic Review
Data in Plant Hormesis Research
High-throughput analyses increase the chances to elucidate physiological processes and ecological interactions of plants from the broadened perspective of systems biology. The generation of big data sets from the simultaneous analysis of an extensive collection of biomolecules corresponding to a definite category (genes, transcripts, proteins, and metabolites) has led to the so-called omics approach, which is the primary tool of systems biology. Furthermore, a multi-omics approach makes it possible to obtain a more detailed snapshot of a plant system by simultaneously analyzing its whole genome, proteome, transcriptome, and metabolome. Moreover, the multi-omics approach applied to single-cell functional analyses can simplify data processing and modeling to accurately depict many biological processes in plants.
  • 695
  • 22 Apr 2022
Topic Review
Phage Therapy on Human and Poultry Infection
Acinetobacter baumannii is a multidrug-resistant and invasive pathogen associated with the etiopathology of both an increasing number of nosocomial infections and is of relevance to poultry production systems. Phage therapy has gained particular importance for the treatment of bacterial infections. Phage therapy represents a potential treatment solution for multidrug-resistant Acinetobacter baumannii.
  • 695
  • 07 Nov 2022
Topic Review
Androgen Receptor as Biomarker in Breast Cancer
Biomarkers can be used for diagnosis, prognosis, and prediction in targeted therapy. The estrogen receptor α (ERα) and human epidermal growth factor receptor 2 (HER2) are standard biomarkers used in breast cancer for guiding disease treatment. The androgen receptor (AR), a nuclear hormone receptor, contributes to the development and progression of prostate tumors and other cancers. With increasing evidence to support that AR plays an essential role in breast cancer, AR has been considered a useful biomarker in breast cancer, depending on the context of breast cancer sub-types. The existing survival analyses suggest that AR acts as a tumor suppressor in ER + ve breast cancers, serving as a favorable prognostic marker. However, AR functions as a tumor promoter in ER-ve breast cancers, including HER2 + ve and triple-negative (TNBC) breast cancers, serving as a poor prognostic factor. AR has also been shown to be predictive of the potential of response to adjuvant hormonal therapy in ER + ve breast cancers and to neoadjuvant chemotherapy in TNBC.  All contents are adapted from You, C.-P.; Leung, M.-H.; Tsang, W.-C.; Khoo, U.-S.; Tsoi, H. Androgen Receptor as an Emerging Feasible Biomarker for Breast Cancer. Biomolecules 2022, 12, 72. https://doi.org/10.3390/biom12010072
  • 694
  • 25 Jan 2022
Topic Review
Flavor Compound Hexanal Content in Chinese Native Chickens
The role of hexanal in flavor as an indicator of the degree of oxidation of meat products is undeniable. However, the genes and pathways of hexanal formation have not been characterized in detail.
  • 694
  • 02 Mar 2022
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