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Topic Review
Diatoms
Diatoms have an ability that is unique among the unicellular photoautotrophic organisms to synthesize an intricately ornamented siliceous (biosilica) exoskeleton with an ordered, hierarchical, three-dimensional structure on a micro- to nanoscale. The unique morphological, structural, mechanical, transport, photonic, and optoelectronic properties of diatomaceous biosilica make it a desirable material for modern technologies. This review presents a summary and discussion of published research on the metabolic insertion of chemical elements with specific functional activity into diatom biosilica. Included in the review is research on innovation in methods of synthesis of a new generation of functional siliceous materials, where the synthesis process is “outsourced” to intelligent microorganisms, referred to here as microtechnologists, by providing them with appropriate conditions and reagents.
  • 2.0K
  • 27 Oct 2020
Topic Review
Castration-Resistant Prostate Cancer
Castration-resistant prostate cancer (CRPC) is defined as castrate serum testosterone levels (<50 ng/dL or 1.7 nmol/L) plus either biochemical or radiological progression, as specified in the European Association of Urology guidelines.
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  • 20 Apr 2021
Topic Review
Environmental Applications of Chitin
Chitin’s environmentally friendly nature has been well documented, further allowing scientists to develop novel techniques utilizing chitin in the environmental sector. Chitin has a very high surface area due to the size of the biopolymer, which is applicable as a pollutant absorber and is used for other modifications that can be made into nanocomposites, best suited for environmental applications for soil and water pollutants.
  • 2.0K
  • 09 Nov 2021
Topic Review
Soybean Tocopherols
Tocopherols are natural antioxidants that increase the stability of fat-containing foods and are well known for their health benefits. The inclination of tocopherol concentrations with various MGs provided further evidence of the significance of MG in soybean breeding for seed tocopherol components. Furthermore, the correlation between the seed tocopherol components and geographical factors revealed that α-, γ-, and total tocopherols had significant positive correlations with latitude, while δ-tocopherol showed an opposite trend. The elite accessions with high and stable tocopherol concentrations determined could be used to develop functional foods, industrial materials, and breeding lines to improve tocopherol composition in soybean seeds.
  • 2.0K
  • 01 Apr 2022
Topic Review
Physical Education and Sports Supported by IoT
The COVID-19 pandemic in recent years and the massive presence of information technology generate one of the biggest challenges facing humanity, namely the technological challenge. Educational technologies have a positive impact on the correct and effective teaching and learning of physical education and sports (PES), with a great positive impact on future sustainable higher education (HE). Various innovative techniques could be of interest, such as the use of social networks and fitness sites, e-learning platforms, computer games, and telephone applications involving video analysis and age-specific images of students and the skills taught. 
  • 2.0K
  • 16 May 2022
Topic Review
Mechanism of Abrasive-Based Finishing Processes
Various manufacturing industries have been using conventional procedures for finishing the components, such as grinding, honing, lapping, etc., to get the machining components’ desired finishing. However, these conventional procedures of finishing are restricted to very few geometries and cannot work on complex and intricate geometries as well as complicated profiles for finishing of high level, which is required while the operation of the component is in process. These limitations and restrictions in the finishing process have led the industries to develop advanced finishing procedures, known as “Abrasive flow machining (AFM)”. Advances in technology and refinement of available computational resources paved the way for the extensive use of computers to model and simulate complex real-world problems difficult to solve analytically. The appeal of simulations lies in the ability to predict the significance of a change to the system under study. The simulated results can be of great benefit in predicting various behaviors, such as the wind pattern in a particular region, the ability of a material to withstand a dynamic load, or even the behavior of a workpiece under a particular type of machining. 
  • 2.0K
  • 29 Sep 2022
Topic Review
Aflatoxin
Aflatoxins are poisonous carcinogens that are produced by certain molds (Aspergillus flavus and Aspergillus parasiticus) which grow in soil, decaying vegetation, hay, and grains. They are regularly found in improperly stored staple commodities such as cassava, chili peppers, corn, cotton seed, millet, peanuts, rice, sesame seeds, sorghum, sunflower seeds, tree nuts, wheat, and a variety of spices. When contaminated food is processed, aflatoxins enter the general food supply where they have been found in both pet and human foods, as well as in feedstocks for agricultural animals. Animals fed contaminated food can pass aflatoxin transformation products into eggs, milk products, and meat. For example, contaminated poultry feed is suspected in the findings of high percentages of samples of aflatoxin-contaminated chicken meat and eggs in Pakistan. Children are particularly affected by aflatoxin exposure, which is associated with stunted growth, delayed development, liver damage, and liver cancer. An association between childhood stunting and aflatoxin exposure has been reported in some studies but could not be detected in all. Furthermore, a causal relationship between childhood stunting and aflatoxin exposure has yet to be conclusively shown by epidemiological studies, though such investigations are underway. Adults have a higher tolerance to exposure, but are also at risk. No animal species is immune. Aflatoxins are among the most carcinogenic substances known. After entering the body, aflatoxins may be metabolized by the liver to a reactive epoxide intermediate or hydroxylated to become the less harmful aflatoxin M1. Aflatoxins are most commonly ingested. However the most toxic type of aflatoxin, B1, can permeate through the skin. The United States Food and Drug Administration (FDA) action levels for aflatoxin present in food or feed is 20 to 300 ppb. The FDA has had occasion to declare both human and pet food recalls as a precautionary measure to prevent exposure. The term "aflatoxin" is derived from the name of one of the molds that produce it, Aspergillus flavus. It was coined around 1960 after its discovery as the source of "Turkey X disease". Aflatoxins form one of the major groupings of mycotoxins.
  • 2.0K
  • 28 Oct 2022
Topic Review
Thermodynamic Potential
A thermodynamic potential (or more accurately, a thermodynamic potential energy) is a scalar quantity used to represent the thermodynamic state of a system. The concept of thermodynamic potentials was introduced by Pierre Duhem in 1886. Josiah Willard Gibbs in his papers used the term fundamental functions. One main thermodynamic potential that has a physical interpretation is the internal energy U. It is the energy of configuration of a given system of conservative forces (that is why it is called potential) and only has meaning with respect to a defined set of references (or data). Expressions for all other thermodynamic energy potentials are derivable via Legendre transforms from an expression for U. In thermodynamics, external forces, such as gravity, are typically disregarded when formulating expressions for potentials. For example, while all the working fluid in a steam engine may have higher energy due to gravity while sitting on top of Mount Everest than it would at the bottom of the Mariana Trench, the gravitational potential energy term in the formula for the internal energy would usually be ignored because changes in gravitational potential within the engine during operation would be negligible. In a large system under even homogeneous external force, like the earth atmosphere under gravity, the intensive parameters ([math]\displaystyle{ p, T, \rho }[/math]) should be studied locally having even in equilibrium different values in different places far from each other (see thermodynamic models of troposphere].
  • 2.0K
  • 04 Nov 2022
Topic Review
Dermal Fibroblasts
Scarring and regeneration are two physiologically opposite endpoints to skin injuries, with mammals, including humans, typically healing wounds with fibrotic scars. We aim to provide an updated review on fibroblast heterogeneity as determinants of the scarring–regeneration continuum. We discuss fibroblast-centric mechanisms that dictate scarring–regeneration continua with a focus on intercellular and cell–matrix adhesion. Improved understanding of fibroblast lineage-specific mechanisms and how they determine scar severity will ultimately allow for the development of antiscarring therapies and the promotion of tissue regeneration.
  • 2.0K
  • 30 Oct 2020
Topic Review
Semiconductor Electrode Materials
Industrial sources of environmental pollution generate huge amounts of industrial wastewater containing various recalcitrant organic and inorganic pollutants that are hazardous to the environment. On the other hand, industrial wastewater can be regarded as a prospective source of fresh water, energy, and valuable raw materials. Conventional sewage treatment systems are often not efficient enough for the complete degradation of pollutants and they are characterized by high energy consumption. Moreover, the chemical energy that is stored in the wastewater is wasted. A solution to these problems is an application of photoelectrocatalytic treatment methods, especially when they are coupled with energy generation. The paper presents a general overview of the semiconductor materials applied as photoelectrodes in the treatment of various pollutants. The fundamentals of photoelectrocatalytic reactions and the mechanism of pollutants treatment as well as parameters affecting treatment processes are presented. Examples of different semiconductor photoelectrodes that are applied in treatment processes are described in order to present the strengths and weaknesses of the photoelectrocatalytic treatment of industrial wastewater. This overview is an addition to the existing knowledge with a particular focus on the main experimental conditions employed in the photoelectrocatalytic degradation of various pollutants with the application of semiconductor photoelectrodes.
  • 2.0K
  • 01 Nov 2020
Topic Review
Classified Urban Land Cover Classes
The urban land cover consists of very complex physical materials and surfaces that are constantly having anthropological impacts. The urban surface types are a mosaic of seminatural surfaces such as grass, trees, bare soil, water bodies, and human-made materials of diverse age and composition, such as asphalt, concrete, roof tiles for energy conservation and fire danger, and generally impervious surfaces for urban flooding studies and pollution. The complexity of urban analysis also depends on the scale chosen and its purpose.
  • 2.0K
  • 15 Sep 2021
Topic Review
3D Printing Technologies in Biosensors Production
Three-dimensional (3D) printing was born in 1986, with the publication of Chuck Hull’s patent, who invented stereolithography; it has evolved and differentiated, with the introduction of new printing techniques and numerous materials with different characteristics. 
  • 2.0K
  • 18 Feb 2022
Topic Review
Myocardial Infarction with Non-Obstructive Coronary Arteries
Myocardial infarction with non-obstructive coronary arteries (MINOCA) is a heterogeneous group of conditions that include both atherosclerotic (coronary plaque disruption) and non-atherosclerotic (spontaneous coronary artery dissection, coronary artery spasm, coronary artery embolism, coronary microvascular dysfunction, and supply–demand mismatch) causes resulting in myocardial damage that is not due to obstructive coronary artery disease. Failure to identify the underlying cause may result in inadequate and inappropriate therapy in these patients.
  • 2.0K
  • 20 Oct 2022
Topic Review
Thummer Keyboard
A Thummer is a proposed commercial musical instrument characterized by The Thummer was to be a type of jammer keyboard. Research suggests that the jammer's combination of thumb-controls and internal motion sensors could give more expressive potential than other polyphonic musical instruments such as the piano, guitar, and accordion. Isomorphic keyboards similar to those used in a jammer have been shown to accelerate the rate at which students grasp otherwise-abstract concepts in music theory.
  • 2.0K
  • 20 Oct 2022
Topic Review
Focused Ultrasound for the Treatment of Brain Tumors
Focused ultrasound technology provides a method for overcoming the blood–brain and blood–tumor barriers through ultrasound frequency to transiently permeabilize or disrupt these barriers. Concomitant delivery of therapeutics has allowed for previously impermeable agents to reach the tumor microenvironment. 
  • 2.0K
  • 13 Jun 2023
Topic Review
Electrocardiogram Signal Denoising
The electrocardiogram (ECG) is widely used in medicine because it can provide basic information about different types of heart disease. 
  • 2.0K
  • 29 Nov 2023
Topic Review
Biological Clocks as Biomarkers of Aging
A key objective in biological aging research is to identify biomarkers capable of predicting the biological age (B-age) of different tissues, as an alternative to relying solely on chronological age (C-age). Biological clock technologies are designed to assess the acceleration of biological age (B-age) in diverse cell types, offering a distinctive opportunity in toxicogenomic research to explore the impact of environmental stressors, social challenges, and unhealthy lifestyles on health impairment. These clocks also play a role in identifying factors that can hinder aging and promote a healthy lifestyle. 
  • 2.0K
  • 29 Dec 2023
Topic Review
Animal Resilience
Resilience is conceived as a dynamic developmental process involving the achievement of positive adaptation within the context of significant adversity. Resilience is not a unique ability but rather a set of capacities of a system put in place to absorb a disturbance and to reorganize while trying to retain the same function, structure, and identity. This study describes the characteristics and the molecular mechanisms of resilience to understand the core elements of resilience and its indicators.
  • 2.0K
  • 08 Jan 2021
Topic Review
Polymer Composites with Carbon Fillers
To address the low thermal conduction of the polymer materials, many kinds of thermally conductive fillers have been studied, and the carbon-based polymer composite is regarded as one of the most promising materials for the thermal management of the electric and electronic devices.
  • 2.0K
  • 25 Jun 2021
Topic Review
Litsea cubeba
Litsea cubeba is a special woody oil plant resource in China, which is mainly distributed in provinces and regions in the south of the Yangtze River. For the past several decades, Litsea cubeba essential oil has been the only product for trading, which can be extracted from its whole plant, including leaves, flowers, fruits, trunks, and even roots. Based on the zero-waste biorefinery concept, residues generated from Litsea cubeba essential oil processing have recently been found as potential sources for various plant-based products with added values, i.e., kernel oil with a high content of medium chain fatty acids might be used for the sustainable production of surfactants or even biofuels, pomace including protein might be used as a good source for feeding.
  • 2.0K
  • 12 Jul 2021
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