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Topic Review
The Mechanisms of Autism
Autism is a neurodevelopmental condition that starts in childhood and continues into adulthood. The core characteristics include difficulties with social interaction and communication, together with restricted and repetitive behaviours. There are a number of key abnormalities of brain structure and function that trigger these behavioural patterns, including an imbalance of functional connectivity and synaptic transmission, neuronal death, gliosis and inflammation. In addition, autism has been linked to alterations in the gut microbiome.
  • 2.0K
  • 04 Nov 2022
Topic Review
Pollen Quality Versus Quantity
Do bees really benefit from the conservation attempts made by us? A study performed recently showed that wild bees do not use plant species sown in wildflower seed mixtures as pollen sources, and it concluded that plant species currently promoted by agri-environmental schemes are not optimal for bees. I have taken a closer look at the factors that determined whether pollen was healthy food for the wild bee larvae or not and the results have led me to propose that a major shift in the perspective of what we considered as bee-friendly plants was definitely warranted.
  • 2.0K
  • 30 Oct 2020
Topic Review
CdTe Solar Cells
Cadmium telluride (CdTe) has achieved a truly impressive development that can commercially compete with silicon, which is still the king of the market. Solar cells made on a laboratory scale have reached efficiencies close to 22%, while modules made with fully automated in-line machines show efficiencies above 18%. Based on the research developed in our laboratory, the fabrication processes of both CdTe polycrystalline thin-film solar cells and photovoltaic modules are critically discussed. The most common substrates, the constituent layers and their interaction, the interfaces and the different “tricks” commonly used for obtaining highly efficient devices will be analyzed.
  • 2.0K
  • 01 Nov 2020
Topic Review
Machine Learning Algorithms for Depression
Over the years, stress, anxiety, and modern-day fast-paced lifestyles have had immense psychological effects on people’s minds worldwide. The global technological development in healthcare digitizes the scopious data, enabling the map of the various forms of human biology more accurately than traditional measuring techniques. Machine learning (ML) has been accredited as an efficient approach for analyzing the massive amount of data in the healthcare domain. ML methodologies are being utilized in mental health to predict the probabilities of mental disorders and, therefore, execute potential treatment outcomes. The ML-based depression detection algorithms are categorized into three classes, classification, deep learning, and ensemble. A general model for depression diagnosis involving data extraction, pre-processing, training ML classifier, detection classification, and performance evaluation is presented.
  • 2.0K
  • 02 Apr 2022
Topic Review
Mobile Computing for Pest and Disease Management
The demand for mobile applications in agriculture is increasing as smartphones are continuously developed and used for many purposes; one of them is managing pests and diseases in crops. Using mobile applications, farmers can detect early infection and improve the specified treatment and precautions to prevent further infection from occurring. Furthermore, farmers can communicate with agricultural authorities to manage their farm from home, and efficiently obtain information such as the spectral signature of crops. Therefore, the spectral signature can be used as a reference to detect pests and diseases with a hyperspectral sensor more efficiently than the conventional method, which takes more time to monitor the entire crop field. 
  • 2.0K
  • 28 Apr 2022
Topic Review
Hybrid Fibre-Coaxial
Hybrid fiber-coaxial (HFC) is a telecommunications industry term for a broadband network that combines optical fiber and coaxial cable. It has been commonly employed globally by cable television operators since the early 1990s. In a hybrid fiber-coaxial cable system, the television channels are sent from the cable system's distribution facility, the headend, to local communities through optical fiber subscriber lines. At the local community, a box called an optical node translates the signal from a light beam to radio frequency (RF), and sends it over coaxial cable lines for distribution to subscriber residences. The fiberoptic trunk lines provide adequate bandwidth[weasel words] to allow future expansion and new bandwidth-intensive services.
  • 2.0K
  • 07 Nov 2022
Topic Review
Attacks on Humanitarian Workers
Humanitarian aid workers belonging to United Nations organisations, PVOs / NGOs or the Red Cross / Red Crescent have traditionally enjoyed both international legal protection, and de facto immunity from attack by belligerent parties. However, attacks on humanitarian workers have occasionally occurred, and became more frequent since the 1990s and 2000s. In 2017, the Aid Worker Security Database (AWSD) documented 139 humanitarian workers killed in intentional attacks out of the estimated global population of 569,700 workers. In every year since 2013, more than 100 humanitarian workers were killed. This is attributed to a number of factors, including the increasing number of humanitarian workers deployed, the increasingly unstable environments in which they work, and the erosion of the perception of neutrality and independence. In 2012 road travel was seen to be the most dangerous context, with kidnappings of aid workers quadrupling in the last decade, reaching more aid workers victims than any other form of attack. The foremost collector of data on attacks against humanitarian workers is the Aid Worker Security Database, which has strict parameters allowing for the data to be compared across the globe over time, producing useful analysis for the humanitarian, policy and academic community. Armed Conflict Location & Event Data Project (ACLED) is another database that includes attacks on humanitarian workers in addition to other conflict related incidents. Insecurity Insight produces monthly Aid in Danger reports that highlight attacks during the month from news media, the AWSD and ACLED.
  • 2.0K
  • 24 Nov 2022
Topic Review
Valorisation of Animal By-Products
The treatment and reduction of animal by-products has registered an increase in the awareness that this type of materials is underutilised and can represent a valuable resource if treated correctly. Consequently, it is no longer practical to dispose of animal by-products, especially when a significant amount of potential raw materials is produced, which can have a high economic potential through the production of new products with significant added value. The reuse and valorisation of animal by-products (ABPs) generated in the food retail sector can involve sending these by-products to another company/organisation or industry, where they will be processed in order to obtain added-value products. This type of valorisation originates an industrial symbiosis.
  • 2.0K
  • 22 Mar 2022
Topic Review
Molecular Classification of Breast Cancer
Breast cancer is the most commonly occurring cancer in women. There were over two-million new cases in world in 2018. It is the second leading cause of death from cancer in western countries. At the molecular level, breast cancer is a heterogeneous disease, which is characterized by high genomic instability evidenced by somatic gene mutations, copy number alterations, and chromosome structural rearrangements. The genomic instability is caused by defects in DNA damage repair, transcription, DNA replication, telomere maintenance and mitotic chromosome segregation. According to molecular features, breast cancers are subdivided in subtypes, according to activation of hormone receptors (estrogen receptor and progesterone receptor), of human epidermal growth factors receptor 2 (HER2), and or BRCA mutations. 
  • 2.0K
  • 26 May 2022
Topic Review
Seaweed Polysaccharides in Agriculture
The seaweed-based biostimulants available in the market are proven to achieve better results than synthetic commercial fertilizers in plant growth parameters. There are many compounds present in seaweeds that are responsible for the plant bioactivities. Seaweed polysaccharides, such as agar, alginate, and carrageenan, make up most of the seaweed biomass and are proven to achieve excellent results in agricultural crops (in poly- and oligosaccharides formula). These types of compounds are reported to improve seed germination and plant vigor, increase the uptake of soil nutrients, and protect plants against several abiotic and biotic stresses such as salinity, drought, temperature, and pathogens. 
  • 2.0K
  • 15 Jun 2023
Topic Review
Magnetic Resonance Imaging on Pregnant Women
Pregnancy is a delicate state, during which timely investigation of possible physiological anomalies is essential to reduce the risk of maternal and fetal complications. Medical imaging encompasses different technologies to image the human body for the diagnosis, course of treatment management, and follow-up of diseases. Ultrasound (US) is currently the imaging system of choice for pregnant patients. However, sonographic evaluations can be non-effective or give ambiguous results. Therefore, magnetic resonance imaging (MRI), due to its excellent tissue penetration, the possibility of acquisition of three-dimensional anatomical information, and its high spatial resolution, is considered a valid diagnostical alternative.
  • 2.0K
  • 19 Apr 2022
Topic Review
Psycho-Neuro-Endocrine-Immune Basis of the Placebo Effect
The placebo effect can be defined as the improvement of symptoms in a patient after the administration of an innocuous substance in a context that induces expectations regarding its effects. During recent years, it has been discovered that the placebo response not only has neurobiological functions on analgesia, but that it is also capable of generating effects on the immune and endocrine systems. Beyond studies about its mechanism of action, the placebo effect has proved to be useful in the clinical setting with promising results in the management of neurological, psychiatric, and immunologic disorders. However, more research is needed to better characterize its potential use. 
  • 2.0K
  • 31 May 2022
Topic Review
Patikulamanasikara
Paṭikkūlamanasikāra (variant: paṭikūlamanasikāra) is a Pāli term that is generally translated as "reflections on repulsiveness". It refers to a traditional Buddhist meditation whereby thirty-one parts of the body are contemplated in a variety of ways. In addition to developing sati (mindfulness) and samādhi (concentration), this form of meditation is considered conducive to overcoming desire and lust. Along with cemetery contemplations, this type of meditation is one of the two meditations on "the foul"/unattractiveness (Pāli: asubha).
  • 2.0K
  • 26 Oct 2022
Topic Review
Khalili Collection of Japanese Art
The Khalili Collection of Japanese Art is a private collection of decorative art from Meiji-era (1868–1912) Japan , assembled by the British-Iranian scholar, collector and philanthropist Nasser D. Khalili. With more than 1,400 objects in total, it is comparable only to the collection of the Japanese imperial family in terms of size and quality. The collection includes metalwork, enamels, ceramics, and lacquered objects, including works by artists of the imperial court that were exhibited at the Great Exhibitions of the late 19th century. Rather than covering the whole range of Meiji-era decorative art, Khalili has focused on objects of the highest technical and artistic quality. He observed that Japanese arts were less well-documented than European arts of the same period, despite being technically superior: "Whilst one could argue it is relatively easy to replicate a Fabergé, to replicate the work of the Japanese master is nigh on impossible." The collection is one of eight assembled, published, and exhibited by Khalili, and one of three that feature art works from Japan, along with the Khalili Collection of Kimono and the Khalili Collection of Enamels of the World. Although the collection is not on permanent public display, its objects are lent to cultural institutions and have appeared in many exhibitions from 1994 onwards. Exhibitions drawing exclusively from the collection have been held at the British Museum, Israel Museum, Van Gogh Museum, Portland Museum, Moscow Kremlin Museums, and other institutions worldwide. As well as assembling these collections, Khalili founded the Kibo Foundation (from the Japanese word for "hope") to promote the study of art and design of the Meiji era, publishing scholarship about the collection and its historical context.
  • 2.0K
  • 08 Nov 2022
Topic Review
Supplementation in In Vitro Tissue Culture Techniques
The growing demand for native planting material in ecological restoration and rehabilitation for agro-silvo-pastoral ecosystems has resulted in a major global industry in their sourcing, multiplication, and sale. Plant tissue culture is used for producing high-quality, disease-free, and true-to-type plants at a fast rate. Micropropagation can help to meet the increasing demand for planting material and afforestation programs.
  • 2.0K
  • 01 Dec 2022
Topic Review
Online Grocery Shopping Experience during the COVID-19 Pandemic
Online shopping has intensified in the last decade. The COVID-19 pandemic has imposed circulation limitations and more restrictive behaviors on consumers due to fears of contracting the virus, boosting online grocery shopping. Online grocery shopping is a form of online shopping for food and other household items processed through e-commerce websites or mobile apps. The studies on online grocery shopping started in the 1990s with the rise of the high-tech generation, who began shopping online for convenience as it simplified their lives. At the beginning of the COVID-19 pandemic, consumers focused on panic buying as they were afraid of future shortages. On the other hand, consumers also wanted to decrease the number of times they went shopping to reduce the risk of catching the virus. To avoid getting infected with the virus when physically going to the shops, some people started shopping for food online.
  • 2.0K
  • 15 Jul 2022
Topic Review
Optimal Design of Neural Networks Based on FPGA
Deep learning based on neural network has been widely used in image recognition, speech recognition, natural language processing, automatic driving and other fields, and has made breakthrough progress. FPGA stands out in the field of accelerated deep learning with its flexible architecture and logical unit, high energy efficiency ratio, strong compatibility, low delay and other advantages.
  • 2.0K
  • 15 Sep 2023
Topic Review
Thin Polymer Films on Glass
Thin polymer films play critical roles in various glass industry applications. They have been used as adhesives in automotive and architecture, an anti-fouling coating layer in touch-screen applications, a substrate for organic light emitting diode, and a protective layer for glass packaging.
  • 2.0K
  • 27 Jul 2021
Topic Review
Rigenera® Micrografts in Oral Regeneration
Biomaterials derive either from nature or synthesized in the laboratory using chemical approaches utilizing metallic components, polymers, ceramics, or composite materials. They are often used and adapted for medical applications. A biomaterial is also defined as autograft, allograft, or xenograft used as a transplant material. In the last decade also tissue engineering and stem cells were deeply studied trying to make better autologous biomaterials ready to be used in regenerative procedures. Micrografts are a new concept of biomaterial, they are enriched of progenitor cells that are a particular type of stem cell excellent in enhancing the regenerative potential. Moreover, another advantage is the easy handling and tissue availability.
  • 2.0K
  • 29 Oct 2020
Topic Review
DUBs Activating Hedgehog Signaling Pathway
The Hedgehog (HH) pathway governs cell proliferation and patterning during embryonic development and is involved in regeneration, homeostasis and stem cell maintenance in adult tissues. The activity of this signaling is finely modulated at multiple levels and its dysregulation contributes to the onset of several human cancers. Ubiquitylation is a coordinated post-translational modification that controls a wide range of cellular functions and signaling transduction pathways. It is mediated by a sequential enzymatic network, in which ubiquitin ligase (E3) and deubiquitylase (DUBs) proteins are the main actors. The dynamic balance of the activity of these enzymes dictates the abundance and the fate of cellular proteins, thus affecting both physiological and pathological processes. Several E3 ligases regulating the stability and activity of the key components of the HH pathway have been identified. Further, DUBs have emerged as novel players in HH signaling transduction, resulting as attractive and promising drug targets.
  • 2.0K
  • 04 Feb 2021
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