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Topic Review
Italian Dietary Supplement Label Database
The Dietary Supplement Label Database in Italy  is developed to gather data to analyse information on dietary supplements. It is one of first works where the FoodEx2 classification system has been adopted and the related food coding procedure could representa useful tool/guide for other compilers and users.  
  • 2.1K
  • 22 Oct 2020
Topic Review
COVID-19 Vaccines
With a death toll of over one million worldwide, the COVID-19 pandemic caused by SARS-CoV-2 has become the most devastating humanitarian catastrophe in recent decades. The fear of acquiring infection and spreading to vulnerable people has severely impacted society’s socio-economic status. To put an end to this growing number of infections and deaths as well as to switch from restricted to everyday living, an effective vaccine is desperately needed. As a result, enormous efforts have been made globally to develop numerous vaccine candidates in a matter of months. Currently, over 30 vaccine candidates are under assessment in clinical trials, with several undergoing preclinical studies.
  • 2.1K
  • 09 Jan 2021
Topic Review
Cisplatin induced Acute Kidney Injury
Administration of the chemotherapeutic agent cisplatin leads to acute kidney injury (AKI). Cisplatin-induced AKI (CIAKI) has a complex pathophysiological map, which has been linked to cellular uptake and efflux, apoptosis, vascular injury, oxidative and endoplasmic reticulum stress, and inflammation. Despite research efforts, pharmaceutical interventions, and clinical trials spanning over several decades, a consistent and stable pharmacological treatment option to reduce AKI in patients receiving cisplatin remains unavailable. This has been predominately linked to the incomplete understanding of CIAKI pathophysiology and molecular mechanisms involved.
  • 2.1K
  • 21 Apr 2021
Topic Review
Polyploidy in Evolution
Polyploidy or whole-genome duplication (WGD) is widespread in nature, agriculture and aquaculture, normal physiology, regeneration, aging, and pathology. WGD results from the premature termination of the cell cycle or cell fusion. If WGD occurs in germ cells, the progeny organisms become completely polyploid, if in somatic cells, the somatic polyploidy arises in certain tissues of a given organism. Polyploidization leads to long-term consequences both in evolution (organismal) and ontogenesis (somatic). In evolution, WGD is one of the main sources for the growth of organismal complexity and evolutionary plasticity
  • 2.1K
  • 08 Apr 2022
Topic Review
Nucleophilic Substitution
A nucleophilic substitution is a class of chemical reactions in which an electron-rich chemical species (known as a nucleophile) replaces a functional group within another electron-deficient molecule (known as the electrophile). The molecule that contains the electrophile and the leaving functional group is called the substrate. The most general form of the reaction may be given as the following: The electron pair (:) from the nucleophile (Nuc) attacks the substrate (R-LG) and bonds with it. Simultaneously, the leaving group (LG) departs with an electron pair. The principal product in this case is R-Nuc. The nucleophile may be electrically neutral or negatively charged, whereas the substrate is typically neutral or positively charged. An example of nucleophilic substitution is the hydrolysis of an alkyl bromide, R-Br under basic conditions, where the attacking nucleophile is OH− and the leaving group is Br−. Nucleophilic substitution reactions are common in organic chemistry (especially introductory organic chemistry). Nucleophiles often attack a saturated aliphatic carbon. Less often, they may attack an aromatic or unsaturated carbon.
  • 2.1K
  • 26 Oct 2022
Topic Review
Citrus Fruit Loss Caused by Pathogens
The Sustainable Development Goals (SDGs) contribute to the improvement of production and consumption systems, hence, assisting in the eradication of hunger and poverty. As a result, there is growing global interest in the direction of economic development to create a zero-waste economy or circular economy. Citrus fruits are a major fruit crop, with annual global production surpassing 100 million tons, while orange and tangerine production alone account for more than half of the overall production. During pre- and postharvest stages of citrus fruit production, it is estimated that more than 20% of fruit biomass is lost, due, primarily, to biotic stresses. Due to substantial changes in fruit characteristics and environmental conditions, some of the most economically significant pathogens infect fruits in the field during the growing season and remain dormant or inactive until they resume growth after harvest. 
  • 2.1K
  • 31 Aug 2022
Topic Review
Comparison of JavaScript Frameworks
There are many JavaScript frameworks available. The intention of this comparison is to show some examples of notable JavaScript frameworks.
  • 2.1K
  • 26 Oct 2022
Topic Review
Basic Properties of Ethics
Ethics is a discipline concerned with good and bad moral values and norms that can be right and wrong. Norms define standards of acceptable behavior by groups. Specific ethical systems, through their norms (computable conventions), constrain and partially solve the problem of life. The importance of ethics for society is paramount, as no social group can stay cohesive and in existence if there are no constraints on the behavior of individuals. For example, frequent, reasonless escalations and attacks with killing or injuring others would dissolve any group. Hence, the problem that ethics tries to solve is improving group performance in a setting that is multi-criteria, dynamic, and poised by uncertainties. It operates on a large societal scale, making for a complex setting in which adaptability is crucial. Ethics emerged collaterally through cultural evolution on a longer time scale where all changes have been slow and gradual.
  • 2.1K
  • 29 Nov 2022
Topic Review
Non-Intrusive Load Monitoring
Non-intrusive load monitoring (NILM) is a process of estimating operational states and power consumption of individual appliances, which if implemented in real-time, can provide actionable feedback in terms of energy usage and personalized recommendations to consumers. Intelligent disaggregation algorithms such as deep neural networks can fulfill this objective if they possess high estimation accuracy and lowest generalization error. In order to achieve these two goals, this paper presents a disaggregation algorithm based on a deep recurrent neural network using multi-feature input space and post-processing. First, the mutual information method was used to select electrical parameters that had the most influence on the power consumption of each target appliance. Second, selected steady-state parameters based multi-feature input space (MFS) was used to train the 4-layered bidirectional long short-term memory (LSTM) model for each target appliance. Finally, a post-processing technique was used at the disaggregation stage to eliminate irrelevant predicted sequences, enhancing the classification and estimation accuracy of the algorithm. A comprehensive evaluation was conducted on 1-Hz sampled UKDALE and ECO datasets in a noised scenario with seen and unseen test cases. Performance evaluation showed that the MFS-LSTM algorithm is computationally efficient, scalable, and possesses better estimation accuracy in a noised scenario, and generalized to unseen loads as compared to benchmark algorithms. Presented results proved that the proposed algorithm fulfills practical application requirements and can be deployed in real-time.
  • 2.1K
  • 28 Oct 2020
Topic Review
Lithium-Sulfur Redox Battery
The lithium-sulfur (Li-S) redox battery system is considered to be the most promising next-generation energy storage technology due to its high theoretical specific capacity (1673 mAh/g), high energy density (2600 Wh/kg), low cost, and environmentally friendly nature of sulfur. Though this system is deemed to be the next-generation energy storage device for portable electronics and electric vehicles, its poor cycle life, low coulombic efficiency, and low rate capability limit it from practical applications. These performance barriers were linked to several issues like polysulfide (LiPS) shuttle, inherent low conductivity of charge/discharge end products, and poor redox kinetics. Here, we review the recent developments made to alleviate these problems through an electrocatalysis approach, which is considered to be an effective strategy not only to trap the LiPS but also to accelerate their conversion reactions kinetics. Herein, the influence of different chemical interactions between the LiPS and the catalyst surfaces and their effect on the conversion of liquid LiPS to solid end products are reviewed. Finally, we also discussed the challenges and perspectives for designing cathode architectures to enable high sulfur loading along with the capability to rapidly convert the LiPS.
  • 2.1K
  • 21 Oct 2020
Topic Review
Alkenylbenzenes and Food
Alkenylbenzenes are potentially toxic (genotoxic and carcinogenic) compounds present in plants such as basil, tarragon, anise star and lemongrass. These plants are found in various edible consumer products, e.g., popularly used to flavour food. Thus, there are concerns about the possible health consequences upon increased exposure to alkenylbenzenes especially due to food intake. It is therefore important to constantly monitor the amounts of alkenylbenzenes in our food chain. 
  • 2.1K
  • 22 Jun 2021
Topic Review
COVID-19: IoT Adoption in Healthcare
COVID-19 has disrupted normal life and has enforced a substantial change in the policies, priorities and activities of individuals, organisations and governments. These changes are proving to be a catalyst for technology and innovation. In this entry, we discuss the pandemic's potential impact on the adoption of the Internet of Things (IoT) in healthcare. Our perspective and forecast of this impact on IoT adoption is based on a thorough research literature review, a careful examination of reports from leading consulting firms and interactions with several industry experts. For each of these sectors, we also provide the details of notable IoT initiatives taken in wake of COVID-19. We also highlight the challenges that need to be addressed and important research directions that will facilitate accelerated IoT adoption.
  • 2.1K
  • 28 Jun 2021
Topic Review
Shade Covers in Water Reservoirs
Shade objects are small plastic spheres, squares or even hexagons floating on top of a water reserve for environmental reasons. The creator of shade balls in California originally used them to prevent chemical treatments in the reservoir from reacting with sunlight creating bromate, which is a carcinogen regulated by many institutions worldwide (chlorine plus sunlight turns bromine into bromate that is a potentially cancer-causing agent; because shady objects stop bromate from forming below, less chlorine is required to treat the water than without them). More recently, other environmental issues have been associated to the use of shade objects: slowing down water evaporation, preventing algae blooms, avoiding birds landing on bodies of water and promote water heating.
  • 2.1K
  • 21 Oct 2021
Topic Review
Biomass-Based Biohydrogen Production
Biohydrogen is a sustainable energy form and a preferable substitute for fossil fuel. Biohydrogen production is eco-friendly compared to other methods of hydrogen production. It has the potential to replace conventional fossil fuels without releasing greenhouse gases. Hydrogen production from biomass depends upon the type of feedstock utilized.
  • 2.1K
  • 09 Feb 2022
Topic Review
Poultry Meat Spoilage and Biogenic Amine Content
Meat is a key element of a balanced diet. Meat consumption has played a significant role in evolution, affecting the development of the human brain. Poultry meat is a source of many important nutrients, micro- and macro-elements, and biologically active substances. During meat storage, many physicochemical changes take place, also affecting the content of biologically active substances, including biogenic amines.
  • 2.1K
  • 04 Jul 2022
Topic Review
Buffon's Needle
In mathematics, Buffon's needle problem is a question first posed in the 18th century by Georges-Louis Leclerc, Comte de Buffon: Buffon's needle was the earliest problem in geometric probability to be solved; it can be solved using integral geometry. The solution, in the case where the needle length is not greater than the width of the strips, can be used to design a Monte Carlo method for approximating the number π, although that was not the original motivation for de Buffon's question.
  • 2.1K
  • 08 Oct 2022
Topic Review
High-Pressure Die Casting Processing Parameters and Die Design
High-pressure die casting (HPDC) is often used to manufacture lightweight structures for automobiles and aeroplanes due to its high productivity and cast dimensional accuracy. The process is characterised by the high-speed injection of molten metal into a sealed mould cavity, followed by solidification under hydrostatic pressures of 30–100 MPa.
  • 2.1K
  • 24 Oct 2022
Topic Review
Salicylic Acid in Root Growth and Development
In plants, salicylic acid (SA) is a hormone that mediates a plant’s defense against pathogens. SA also takes an active role in a plant’s response to various abiotic stresses, including chilling, drought, salinity, and heavy metals. In addition, in recent years, numerous studies have confirmed the important role of SA in plant morphogenesis.
  • 2.1K
  • 10 Mar 2022
Topic Review
Differential Diagnosis of Carpal Tunnel Syndrome
Carpal tunnel syndrome (CTS) is the most common median nerve compression neuropathy. Its symptoms and clinical presentation are well known. However, symptoms at median nerve distribution can also be caused by a proximal problem. Pronator syndrome (PS) and anterior interosseous nerve syndrome (AINS) with their typical characteristics have been thought to explain proximal median nerve problems.
  • 2.1K
  • 27 Jul 2022
Topic Review
Impact of the Internet of Things on Psychology
The Internet of things (IoT) is a network of smart things that can interact without human intervention. The IoT has affected different aspects of human life and led to the Fourth Industrial Revolution. Psychology is an important area of human life affected by the IoT. Inner peace has always been a human concern, for which the principles of psychology must be analyzed and practiced. IoT technology has come to the aid of psychologists in analyzing and resolving prominent psychological problems. 
  • 2.1K
  • 26 Sep 2022
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