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Topic Review
Phages and Intestinal Dysbiosis
Gastrointestinal tract microbiota plays a key role in the regulation of the pathogenesis of several gastrointestinal diseases. In particular, the viral fraction, composed essentially of bacteriophages, influences homeostasis by exerting selective pressure on the bacterial communities living in the tract. The inflamed gut is associated with an SOS response regulated by an increase in resident intestinal pathogenic bacteria, loss of phage diversity, and induction of prophages.
  • 2.1K
  • 09 Nov 2020
Topic Review
Urban Overheating in Australia
Cities in Australia are experiencing unprecedented levels of urban overheating, which has caused a significant impact on the country’s socioeconomic environment. This study provides a comprehensive review on urban overheating, its impact on health, energy, economy, and the heat mitigation potential of a series of strategies in Australia. Existing studies show that the average urban heat island (UHI) intensity ranges from 1.0 °C to 13.0 °C. The magnitude of urban overheating phenomenon in Australia is determined by a combination of UHI effects and dualistic atmospheric circulation systems (cool sea breeze and hot desert winds). The strong relation between multiple characteristics contribute to dramatic fluctuations and high spatiotemporal variabilities in urban overheating. In addition, urban overheating contributes to serious impacts on human health, energy costs, thermal comfort, labour productivity, and social behaviour. 
  • 2.1K
  • 16 Nov 2020
Topic Review
Interferon-Based Biopharmaceuticals
Interferons are secreted autocrine and paracrine proteins, which by regulating several biochemical pathways have a spectrum of clinical effectiveness against viral infections, malignant diseases, and multiple sclerosis. 
  • 2.1K
  • 16 May 2021
Topic Review
Colchicine in Managing Skin Conditions
Colchicine is a natural alkaloid with anti-inflammatory properties used to treat various disorders, including some skin diseases. Colchicine could be, as a single therapy or in combination with other drugs, a possible treatment to manage several skin diseases.
  • 2.1K
  • 13 Apr 2022
Topic Review
Fundamentals of Path-Planning Algorithms
The rapid technological development of computing power and system operations today allows for increasingly advanced algorithm implementation, as well as path planning in real time.
  • 2.1K
  • 12 Aug 2022
Topic Review
Comparison of VMware Fusion and Parallels Desktop
Represented by their respective products, VMware and Parallels, Inc. are the two commercial competitors in the Mac consumer platform virtualization market. Both products are based on hypervisor technology and allow users to run an additional 32- or 64-bit x86 operating system in a virtual machine alongside Mac OS X on an Intel-powered Mac. The similarity in features and functionality between VMware Fusion and Parallels Desktop for Mac has given occasion for much comparison.
  • 2.1K
  • 28 Sep 2022
Topic Review
Submarine Canyon
A submarine canyon is a steep-sided valley cut into the seabed of the continental slope, sometimes extending well onto the continental shelf, having nearly vertical walls, and occasionally having canyon wall heights of up to 5 km, from canyon floor to canyon rim, as with the Great Bahama Canyon. Just as above-sea-level canyons serve as channels for the flow of water across land, submarine canyons serve as channels for the flow of turbidity currents across the seafloor. Turbidity currents are flows of dense, sediment laden waters that are supplied by rivers, or generated on the seabed by storms, submarine landslides, earthquakes, and other soil disturbances. Turbidity currents travel down slope at great speed (as much as 70 km/h), eroding the continental slope and finally depositing sediment onto the abyssal plain, where the particles settle out. About 3% of submarine canyons include shelf valleys that have cut transversely across continental shelves, and which begin with their upstream ends in alignment with and sometimes within the mouths of large rivers, such as the Congo River and the Hudson Canyon. About 28.5% of submarine canyons cut back into the edge of the continental shelf, whereas the majority (about 68.5%) of submarine canyons have not managed at all to cut significantly across their continental shelves, having their upstream beginnings or "heads" on the continental slope, below the edge of continental shelves. The formation of submarine canyons is believed to occur as the result of at least two main process: 1) erosion by turbidity current erosion; and 2) slumping and mass wasting of the continental slope. While at first glance, the erosion patterns of submarine canyons may appear to mimic those of river-canyons on land, due to the markedly different erosion processes that have been found to take place underwater at the soil/ water interface, several notably different erosion patterns have been observed in the formation of typical submarine canyons. Many canyons have been found at depths greater than 2 km below sea level. Some may extend seawards across continental shelves for hundreds of kilometres before reaching the abyssal plain. Ancient examples have been found in rocks dating back to the Neoproterozoic. Turbidites are deposited at the downstream mouths or ends of canyons, building an abyssal fan.
  • 2.1K
  • 09 Nov 2022
Topic Review
Bâton de Commandement
A bâton de commandement, bâton percé or perforated baton is a name given by archaeologists to a particular prehistoric artifact that has been much debated. The name bâtons de commandement was the name first applied to the class of artifacts, but it makes an assumption of function; the name bâton percé, meaning "pierced rod", or "perforated baton" (the term used by the British Museum) is a more recent term, and is descriptive of form rather than any presumed function. Many are decorated with carved or engraved animals, and the most usual explanation of their use is that they were used for straightening spears and arrows, and as spear-throwers.
  • 2.1K
  • 28 Sep 2022
Topic Review
Commercial Crew Development
Commercial Crew Development (CCDev) is a human spaceflight development program that is funded by the U.S. government and administered by NASA. CCDev will result in US and international astronauts flying to the International Space Station (ISS) on privately operated crew vehicles. Operational contracts to fly astronauts were awarded in September 2014 to SpaceX and Boeing. An uncrewed test flight was performed by each company in 2019. Space-X's Crew Dragon Demo-1 flight of Dragon 2 arrived at the International Space Station in March 2019 and returned via splashdown in the Atlantic Ocean. Due to a Mission Elapsed Time anomaly, the Boeing Orbital Flight Test of the CST-100 spacecraft failed to reach the station in December 2019, but completed some test objectives and performed a safe airbag landing in the New Mexico desert two days after launch. Pending completion of the demonstration flights, each company is contracted to supply six flights to ISS between 2019 and 2024. The first group of astronauts was announced on 3 August 2018.
  • 2.1K
  • 26 Oct 2022
Topic Review
Sulfate Reduction in Intestinal Bacteria
Sulfate is present in foods, beverages, and drinking water. Its reduction and concentration in the gut depend on the intestinal microbiome activity, especially sulfate-reducing bacteria (SRB), which can be involved in inflammatory bowel disease (IBD). Assimilatory sulfate reduction (ASR) is present in all living organisms. In this process, sulfate is reduced to hydrogen sulfide and then included in cysteine and methionine biosynthesis. In contrast to assimilatory sulfate reduction, the dissimilatory process is typical for SRB. A terminal product of this metabolism pathway is hydrogen sulfide, which can be involved in gut inflammation and also causes problems in industries (due to corrosion effects).
  • 2.1K
  • 26 May 2021
Topic Review
Gravitation
In physics, gravitation or gravity is the tendency of objects with mass to accelerate toward each other. Gravitation is one of the four fundamental interactions in nature, the other three being the electromagnetic force, the weak nuclear force, and the strong nuclear force. Gravitation is the weakest of these interactions, but acts over great distances and is always attractive. In classical mechanics, gravitation arises out of the force of gravity (which is often used as a synonym for gravitation). In general relativity, gravitation arises out of spacetime being curved by the presence of mass, and is not a force. In quantum gravity theories, either the graviton is the postulated carrier of the gravitational force, or time-space itself is envisioned as discrete in nature, or both. Classically, the gravitational attraction of the earth endows objects with weight and causes them to fall to the ground when dropped (the earth also moves toward the object, but only by an infinitesimal amount). Moreover, gravitation is the reason for the very existence of the earth, the sun, and other celestial bodies; without it matter would not have coalesced into these bodies and life as we know it would not exist. Gravitation is also responsible for keeping the earth and the other planets in their orbits around the sun, the moon in its orbit around the earth, for the formation of tides, and for various other natural phenomena that we observe.
  • 2.1K
  • 14 Oct 2022
Topic Review
Deep Learning for Automated Visual Inspection
This article evaluates the state of the art of deep-learning-based automated visual inspection in manufacturing and maintenance applications and contrasts it to academic research in the field of computer vision. By doing so itidentifies to what extent computer vision innovations are already being used and which potential improvements could be realized by further transferring promising concepts. Existing work is either focused on specific industry sectors or methodologies but not on industrial VI as a whole or is outdated by almost two decades. We surveyed 196 open access publications from 2010 to March 2023 from the fields of manufacturing and maintenance with no restriction regarding industries. Our main findings were: The vast majority of publications utilize supervised learning approaches on relatively small datasets with convolutional neural networks. The timegap between publication of new approaches in deep learning-based computer vision and its first application in industrial visual inspection is approximately three years First vision transformer models emerge in 2022 and seem to outperform established models but their excellent self-supervised learning capabilities are not explored to date
  • 2.1K
  • 26 Feb 2024
Topic Review
Label-Free SERS Analysis of Exosomes
Exosomes are emerging as one of the most intriguing cancer biomarkers in modern oncology for early cancer diagnosis, prognosis and treatment monitoring. Concurrently, several nanoplasmonic methods have been applied and developed to tackle the challenging task of enabling the rapid, sensitive, affordable analysis of exosomes.
  • 2.1K
  • 23 Jun 2021
Topic Review
Methanotrophic Bacteria in Wastewater Treatment
Wastewater treatment plants and other remediation facilities serve important roles, both in public health, but also as dynamic research platforms for acquiring useful resources and biomolecules for various applications. An example of this is methanotrophic bacteria within anaerobic digestion processes in wastewater treatment plants. These bacteria are an important microbial source of many products including ectoine, polyhydroxyalkanoates, and methanobactins, which are invaluable to the fields of biotechnology and biomedicine.
  • 2.1K
  • 10 Sep 2021
Topic Review
Creative Accounting
The main function behind the conceptualization of creative accounting is maintaining the quality of financial reporting practice. Basically, creative accounting is the practice of influencing financial indicators through accounting knowledge without explicitly violating accounting policies, rules, and laws. Creative accounting is practiced to demonstrate the financial status desired by the company management wherein the stakeholders are informed what the management wants them to perceive. It facilitates the manipulation of financial information in its proper and accurate form in which the preparer uses the existing rules or in many cases ignores one or more rules.
  • 2.1K
  • 27 Apr 2022
Topic Review
Chicken Diseases by Monitoring Clinical Symptoms
Automatic disease detection and early warning technology based on clinical symptoms have the potential to monitor poultry health status in a real-time, fast and non-destructive way. The detection of poultry diseases is usually based on the sound characteristics, body temperature characteristics, fecal characteristics, production characteristics (water intake, feed intake and so on), activity characteristics and posture characteristics of the animals. lists the comparison of five clinical symptoms used for the early warning of disease.
  • 2.1K
  • 15 Aug 2022
Topic Review
Rick Perry
James Richard "Rick" Perry (born March 4, 1950) is an American politician who served as the 14th United States Secretary of Energy from 2017 to 2019. A member of the Republican Party, he previously served as the 47th Governor of Texas from 2000 to 2015, having been elected Lieutenant Governor of Texas in 1998 and later assuming the office from George W. Bush. Perry ran unsuccessfully for the nomination for President of the United States in 2012 and 2016. President Donald Trump nominated him as Secretary of Energy; he was confirmed by the United States Senate in a 62–37 vote on March 2, 2017. On October 17, 2019, Perry reported to President Trump that he intended to resign as Secretary of Energy at the end of the year. He left office on December 1, 2019.
  • 2.1K
  • 14 Oct 2022
Topic Review
Astrooceanography
Astrooceanography is the study of oceans outside planet Earth. Unlike other planetary sciences like astrobiology, astrochemistry and planetary geology, it only began after the discovery of underground oceans in Saturn's Titan and Jupiter's Ganymede. This field remains speculative until further missions reach the oceans beneath the rock or ice layer of the moons. There are many theories about oceans or even ocean worlds of celestial bodies in the Solar System, from oceans made of diamond in Neptune to a gigantic ocean of liquid hydrogen that may exist underneath Jupiter's surface. Early in their geologic histories, Mars and Venus are theorized to have had large water oceans. The Mars ocean hypothesis suggests that nearly a third of the surface of Mars was once covered by water, and a runaway greenhouse effect may have boiled away the global ocean of Venus. Compounds such as salts and ammonia dissolved in water lower its freezing point so that water might exist in large quantities in extraterrestrial environments as brine or convecting ice. Unconfirmed oceans are speculated beneath the surface of many dwarf planets and natural satellites; notably, the ocean of the moon Europa is estimated to have over twice the water volume of Earth. The Solar System's giant planets are also thought to have liquid atmospheric layers of yet to be confirmed compositions. Oceans may also exist on exoplanets and exomoons, including surface oceans of liquid water within a circumstellar habitable zone. Ocean planets are a hypothetical type of planet with a surface completely covered with liquid. Astrooceanography is closely related to Astrobiology, as oceans are expected to have higher chances to house simple forms of life.
  • 2.1K
  • 01 Nov 2022
Topic Review
Polymers Used in Microfluidic Devices
Polymers are sustainable and renewable materials that are in high demand due to their excellent properties. Natural and synthetic polymers with high flexibility, good biocompatibility, good degradation rate, and stiffness are widely used for various applications, such as tissue engineering, drug delivery, and microfluidic chip fabrication. Indeed, the advances in microfluidic technology allow the fabrication of polymeric matrix to construct microfluidic scaffolds for tissue engineering and to set up a well-controlled microenvironment for manipulating fluids and particles. 
  • 2.1K
  • 01 Dec 2022
Topic Review
Autophagy and Apoptotic Pathways in Multiple Myeloma
Multiple myeloma (MM) is caused by aberrant plasma cells (PCs) in the bone marrow (BM), representing 1% of neoplastic diseases and 13% of hematological neoplasms. MM is a challenging cancer to diagnose and treat.
  • 2.1K
  • 16 Jan 2023
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