Topic Review
Metal Oxide Applications
Metal oxides play a key role in environmental remediation.
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  • 08 Dec 2020
Topic Review
Hoveyda–Grubbs Catalyst
Hoveyda–Grubbs-type complexes, ruthenium catalysts for olefin metathesis, have gained increased interest as a research target in the interdisciplinary research fields of chemistry and biology because of their high functional group selectivity in olefin metathesis reactions and stabilities in aqueous media.
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  • 26 Mar 2021
Topic Review
Prajñā (Hinduism)
Pragña or Pragya (Sanskrit: प्रज्ञ) as प्रज्ञा, प्राज्ञ and प्राज्ञा is used to refer to the highest and purest form of wisdom, intelligence and understanding. Pragya is the state of wisdom which is higher than the knowledge obtained by reasoning and inference.
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  • 25 Oct 2022
Topic Review
Pentium FDIV Bug
The Pentium FDIV bug is a hardware bug affecting the floating point unit (FPU) of the early Intel Pentium processors. Because of the bug, the processor might return incorrect binary floating point results when dividing a number. The bug was discovered in 1994 by Professor Thomas R. Nicely at Lynchburg College. Intel attributed the error to missing entries in the lookup table used by the floating-point division circuitry. The severity of the FDIV bug is debated. Though rarely encountered by most users (Byte magazine estimated that 1 in 9 billion floating point divides with random parameters would produce inaccurate results), both the flaw and Intel's initial handling of the matter were heavily criticized by the tech community. In December 1994, Intel recalled the defective processors. In January 1995, Intel announced "a pre-tax charge of $475 million against earnings, ostensibly the total cost associated with replacement of the flawed processors."
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  • 04 Nov 2022
Topic Review
Deep Reinforcement Learning Applications
Deep Reinforcement Learning (DRL) combines Reinforcement Learning and Deep Learning. It is more capable of learning from raw sensors or images as input, enabling end-to-end learning, which opens up more applications in robotics, video games, NLP, computer vision, healthcare, and more. A milestone in value-based DRL is employing Deep Q-Networks (DQN) to play Atari games by Google DeepMindin 2013.
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  • 02 Aug 2021
Topic Review
German Student Movement
The German student movement (also called 68er-Bewegung, movement of 1968, or soixante-huitards) was a protest movement that took place during the late 1960s in West Germany. It was largely a reaction against the perceived authoritarianism and hypocrisy of the West German government and other Western governments, and the poor living conditions of students. A wave of protests—some violent—swept West Germany, fueled by violent over-reaction by the police and encouraged by contemporary protest movements across the world. Following more than a century of conservatism among German students, the German student movement also marked a significant major shift to the left and radicalization of student activism.
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  • 03 Nov 2022
Topic Review
Caret
The caret (/ˈkærɪt/) is a V-shaped grapheme, usually inverted and sometimes extended, used in proofreading and typography to indicate that additional material needs to be inserted at this point in the text. There is a similar mark, ^, that has a variety of uses in programming, mathematics and other contexts. The symbol was included in typewriters and computer printers so that circumflex accents could be overprinted on letters (as in ô or ŵ). The character became reused in computer languages for many other purposes, and over time its appearance was enlarged and lowered, making it unusable as an accent mark. This symbol is often called a "caret", but this page will call it a "circumflex" to distinguish it from a true caret. This circumflex is not to be confused with other chevron-shaped characters, such as the circumflex accent, the turned v or the logical AND, which may occasionally be called carets.
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  • 09 Oct 2022
Topic Review
Cybersecurity Economics
Cybersecurity economics can be defined as a field of research that utilizes a socio-technical perspective to investigate economic aspects of cybersecurity such as budgeting, information asymmetry, governance, and types of goods and services, to provide sustainable policy recommendations, regulatory options, and practical solutions that can substantially improve the cybersecurity posture of the interacting agents in the open socio-technical systems.   
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  • 15 Dec 2021
Topic Review
Aparigraha
In Hinduism and Jainism, aparigraha (Sanskrit: अपरिग्रह) is the virtue of non-possessiveness, non-grasping or non-greediness. Aparigrah is the opposite of parigrah, and refers to keeping the desire for possessions to what is necessary or important, depending on one's life stage and context. The precept of aparigraha is a self-restraint (temperance) from the type of greed and avarice where one's own material gain or happiness comes by hurting, killing or destroying other human beings, life forms or nature. Aparigraha is related to and in part a motivator of dāna (proper charity), both from giver's and receiver's perspective.
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  • 13 Oct 2022
Topic Review
Control Freak
In the slang of psychology, the colloquial term control freak describes a person with a personality disorder characterized by undermining other people, usually by way of controlling behavior manifested in the ways that they act to dictate the order of things in a social situation. The term control freak was first used in the 1970s, a decade when the cultural Zeitgeist featured liberal social norms, which espoused the live-and-let-live principle of "Do your own thing" in opposition to the perceived requirement of social conformity within traditional conservatism.
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  • 19 Oct 2022
Topic Review
Eyelash Curler
An eyelash curler is a hand-operated mechanical device for curling eyelashes for cosmetic purposes. Usually only the upper eyelashes are curled.
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  • 25 Nov 2022
Topic Review
Spray Congealing Technology
Spray congealing is an emerging technology for the production of solid dispersion to enhance the bioavailability of poorly soluble drugs by using low-melting hydrophilic excipients. Since the '90s, spray congealing technology has been used to obtain microparticles (MPs) for controlled release, taste masking and stability enhancement of APIs. The main advantages are the absence of solvents and the possibility to obtain free-flowing MPs by a relatively inexpensive, simple and one step process. This entry focused on the application of spary congealing as an amerging technology for the production of solid dispersions to enhance the bioavailability of poorly water soluble drugs by using low-melting hydrophilic excipients.
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  • 14 Dec 2021
Topic Review
MOFs and COFs
Metal-organic frameworks (MOFs) and covalent organic frameworks (COFs) are two innovative classes of porous coordination polymers. MOFs are three-dimensional materials made up of secondary building blocks comprised of metal ions/clusters and organic ligands whereas COFs are 2D or 3D highly porous organic solids made up by light elements (i.e., H, B, C, N, O). Both MOFs and COFs, being highly conjugated scaffolds, are very promising as photoactive materials for applications in photocatalysis and artificial photosynthesis because of their tunable electronic properties, high surface area, remarkable light and thermal stability, easy and relative low-cost synthesis, and structural versatility. 
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  • 08 Dec 2020
Topic Review
Seaport
Seaports are well known as the medium that has evolved into the central link between sea and land for complex marine activities. The growth in maritime logistics particularly necessitates a large volume of energy supply in order to maintain the operation of sea trade, resulting in an imbalance between generation and demand sides. Future projections for three major concerns show an increase in load demand, cost of operation, and environmental issues. The involvement of a variety of heavy loads such as all-electric ships, cranes, cold ironing, and buildings infrastructure renders it a complicated arrangement task in several aspects, which necessitates further research and leaves space for improvement.
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  • 06 Dec 2021
Topic Review
Flaws of Sustainable Development
In 2015, the United Nations (UN) introduced 17 Sustainable Development Goals (SDGs) and 169 associated targets, addressing poverty, hunger, climate change, environmental degradation, peace, justice, and other global issues, as a “blueprint to achieve a better and more sustainable future for all people and the world by 2030”. Thirty years after the Rio Earth Summit, the report from the United Nations on progress towards the Sustainable Development Goals (SDGs) may justifiably trigger some anger. Greater numbers of people are suffering, environments are being further degraded, and the life support systems for both current and future generations are being seriously compromised. About halfway through the time period for the SDGs, in March 2022, UN Secretary-General António Guterres warned that humanity is “moving backwards in relation to the majority of the Sustainable Development Goals”. Although some of the setbacks could be attributed to the pandemic and associated policies, the SDGs were already off-track before COVID-19 emerged.
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  • 08 Oct 2022
Topic Review
Design Considerations of Fixed and Floating Offshore Structures
Offshore structures exist in a variety of forms, and they are used for a variety of functions in varied sea depths. These structures are tailored for certain environments and sea depths and other design considerations. 
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  • 29 Jul 2022
Topic Review
Coumarin
Coumarin (2H-1-benzopyran-2-one) is an oxygen containing heterocycle and belongs to the subcategory of lactones.
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  • 06 Jan 2021
Topic Review
Extraction of Peanut Skins
In addition to the edible kernel, the peanut seed consists of the woody outer shell and a paper-like substance that surrounds the kernel itself known as the testa or skin.
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  • 28 Jan 2021
Topic Review
The Pathogenesis of Epilepsy
Epilepsy is a chronic neurological disorder characterized by recurring spontaneous seizures. Drug resistance appears in 30% of patients and it can lead to premature death, brain damage or a reduced quality of life. The purpose of the study was to analyze the drug resistance mechanisms, especially neuroinflammation, in the epileptogenesis. The information bases of biomedical literature Scopus, PubMed, Google Scholar and SciVerse were used. To obtain full-text documents, electronic resources of PubMed Central and Research Gate were used. The article examines the recent research of the mechanisms of drug resistance in epilepsy and discusses the hypotheses of drug resistance development (genetic, epigenetic, target hypothesis, etc.). Drug-resistant epilepsy is associated with neuroinflammatory, autoimmune and neurodegenerative processes. Neuroinflammation causes immune, pathophysiological, biochemical and psychological consequences. Focal or systemic unregulated inflammatory processes lead to the formation of aberrant neural connections and hyperexcitable neural networks. Inflammatory mediators affect the endothelium of cerebral vessels, destroy contacts between endothelial cells and induce abnormal angiogenesis (the formation of “leaky” vessels), thereby affecting the blood–brain barrier permeability. Thus, the analysis of pro-inflammatory and other components of epileptogenesis can contribute to the further development of the therapeutic treatment of drug-resistant epilepsy.
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  • 26 May 2021
Topic Review
Magellan's Circumnavigation
In 1519, the Portuguese naval officer and explorer Ferdinand Magellan led a Spanish expedition to find a western route to the East Indies and reach the Moluccas or Spice Islands (in present day Indonesia) with a fleet known as the Armada de Molucca. After the death of Magellan in the Philippines in 1521 and following several other short-lived leaderships, Spanish navigator Juan Sebastián Elcano led the expedition to the Spice Islands and ultimately across the Indian Ocean and up the Atlantic ocean back to Spain, resulting in the first circumnavigation of the world in 1522. The expedition is therefore also known as the Magellan–Elcano circumnavigation. The goal of the expedition was to find a western route to the Moluccas (Spice Islands) and trade for spices. Magellan left Spain on 20 September 1519, sailed across the Atlantic, and discovered the strait that now bears his name, allowing him to pass through the southern tip of South America into the Pacific Ocean (which he named). The fleet performed the first ever crossing of the Pacific, stopping in what is today called the Philippines , and eventually reached the Moluccas, accomplishing its goal. A much-depleted crew finally returned to Spain on 6 September 1522. The fleet initially consisted of about 270 men and five ships: four carracks and one caravel. The expedition faced numerous hardships including mutinies, starvation, scurvy, storms, and hostile encounters with indigenous people. Magellan died in battle in the Philippine islands and was succeeded as captain-general by a series of officers, with Juan Sebastián Elcano leading the trip onward to Spain. He and seventeen other men in one ship (the Victoria) were the only ones to circumnavigate the globe. The expedition was funded mostly by King Charles I of Spain, with the hope that it would discover a profitable western route to the Moluccas, as the eastern route was controlled by Portugal under the Treaty of Tordesillas. Though the expedition did find a route, it was much longer and more arduous than expected, and was therefore not commercially useful. Nevertheless, the first circumnavigation has been regarded as a great achievement in seamanship, and had a significant impact on the European understanding of the world.
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  • 16 Nov 2022
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