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Topic Review
Influence Radius of Pumping Well
The influence radius was originally used in the calculation of some hydrogeological parameters but, owing to various coincidences that occur in practical situations, it has been considered that the parameterized influence radius is reasonable and convenient for calculations pertaining to actual production problems, and this misconception has perpetuated. However, by considering the continuity principle of flow, it can be proven that the parameterized influence radius does not exist. The influence radius is essentially the distance in the time–distance problem in physics and is influenced by the hydrogeological conditions and pumping conditions, which is different from the hydrogeological parameters reflecting the natural properties of aquifers, such as the porosity, specific yield, and hydraulic conductivity.
  • 6.5K
  • 18 Aug 2021
Topic Review
Venusians
In science fiction and in the beliefs of ufology, a Venusian (/vɪˈnjuːʒən, -ʃən/) or Venerian is a native inhabitant of the planet Venus. Many science fiction writers have imagined what extraterrestrial life on Venus might be like.
  • 6.5K
  • 21 Oct 2022
Topic Review
Bodybuilding and Myostatin
MSTN is a gene that makes instructions for producing the protein myostatin, a protein that is part of the transforming growth factor beta family (TGFβ). The TGFβ family of proteins control the growth of tissues in the body, myostatin is found nearly exclusively in the skeletal muscles where it is active before and after birth. The protein actually controls skeletal growth by restraining it, preventing muscles becoming excessively large. Current research that surrounds myostatin is based around its potential treatment in muscle wasting disorders, animals that have mutations in the encoding gene MSTN show greater muscle mass, strength and in some circumstances reduced bodyfat, which can be known as myostatin-related muscle hypertrophy. This study aimed to see the prevalence of mutations in the male bodybuilder population (n = 92) and if having a mutation had any affect on their muscle size and/or muscle performance. The study which looked at mutation prevalence in rs1805086, arm circumference, pull-up max and push-up max. The results show that 17% (16) of the subject group had one mutation (AG), 83% (76) had the common outcome (AA) and 0% (0) had two mutations (GG). Those with the AG outcome had an average arm circumference of 46.37cmcompared with AA which had an average of 42.02cm. Those with the AG outcome had an average pull-up max score of 21 compared with AA with an average of 12. Those with the AG outcome had an average push-up max of 61 compared with AA with an average of 40. The study clearly shows that those with a mutation are rare, however the mutation does appear to give the subject a performance and size advantage over those with the common outcome.
  • 6.5K
  • 03 Nov 2020
Topic Review
Natural Biopolymers
Natural biopolymers are an interesting resource for edible films production, as they are environmentally friendly packaging materials.
  • 6.5K
  • 23 Jun 2021
Topic Review
Type 3 Diabetes
The exact connection between Alzheimer’s disease (AD) and type 2 diabetes is still in debate. However, poorly controlled blood sugar may increase the risk of developing Alzheimer’s. This relationship is so strong that some have called Alzheimer’s “diabetes of the brain” or “type 3 diabetes (T3D)”. Given more recent studies continue to indicate evidence linking T3D with AD, this state-of-the-art aimed to demonstrate the relationship between T3D and AD based on the fact that both the processing of amyloid-β (Aβ) precursor protein toxicity and the clearance of Aβ are attributed to impaired insulin signaling, and that insulin resistance mediates the dysregulation of bioenergetics and progress to AD. 
  • 6.5K
  • 29 Oct 2020
Topic Review
Evolutionary Psychology Controversy
The purpose of this article is to outline the various criticisms of evolutionary psychology, as well as counterarguments to these criticisms.
  • 6.5K
  • 08 Oct 2022
Topic Review
Slope Stability Analysis
Slope stability analysis is performed to assess the safe design of a human-made or natural slopes (e.g. embankments, road cuts, open-pit mining, excavations, landfills etc.) and the equilibrium conditions. Slope stability is the resistance of inclined surface to failure by sliding or collapsing. The main objectives of slope stability analysis are finding endangered areas, investigation of potential failure mechanisms, determination of the slope sensitivity to different triggering mechanisms, designing of optimal slopes with regard to safety, reliability and economics, designing possible remedial measures, e.g. barriers and stabilization. Successful design of the slope requires geological information and site characteristics, e.g. properties of soil/rock mass, slope geometry, groundwater conditions, alternation of materials by faulting, joint or discontinuity systems, movements and tension in joints, earthquake activity etc. The presence of water has a detrimental effect on slope stability. Water pressure acting in the pore spaces, fractures or other discontinuities in the materials that make up the pit slope will reduce the strength of those materials. Choice of correct analysis technique depends on both site conditions and the potential mode of failure, with careful consideration being given to the varying strengths, weaknesses and limitations inherent in each methodology. Before the computer age stability analysis was performed graphically or by using a hand-held calculator. Today engineers have a lot of possibilities to use analysis software, ranges from simple limit equilibrium techniques through to computational limit analysis approaches (e.g. Finite element limit analysis, Discontinuity layout optimization) to complex and sophisticated numerical solutions (finite-/distinct-element codes). The engineer must fully understand limitations of each technique. For example, limit equilibrium is most commonly used and simple solution method, but it can become inadequate if the slope fails by complex mechanisms (e.g. internal deformation and brittle fracture, progressive creep, liquefaction of weaker soil layers, etc.). In these cases more sophisticated numerical modelling techniques should be utilised. Also, even for very simple slopes, the results obtained with typical limit equilibrium methods currently in use (Bishop, Spencer, etc.) may differ considerably. In addition, the use of the risk assessment concept is increasing today. Risk assessment is concerned with both the consequence of slope failure and the probability of failure (both require an understanding of the failure mechanism). Within the last decade (2003) Slope Stability Radar has been developed to remotely scan a rock slope to monitor the spatial deformation of the face. Small movements of a rough wall can be detected with sub-millimeter accuracy by using interferometry techniques.
  • 6.5K
  • 19 Oct 2022
Topic Review
Criticism of Jehovah's Witnesses
Jehovah's Witnesses have received criticism from mainstream Christianity, members of the medical community, former members, and commentators regarding their beliefs and practices. The movement has been accused of doctrinal inconsistency and reversals, failed predictions, mistranslation of the Bible, harsh treatment of former members and autocratic and coercive leadership. Criticism has also focused on their rejection of blood transfusions, particularly in life-threatening medical situations, and claims that they have failed to report cases of sexual abuse to the authorities. Many of the claims are denied by Jehovah's Witnesses and some have also been disputed by courts and religious scholars.
  • 6.5K
  • 18 Nov 2022
Biography
Eckhart Tolle
Eckhart Tolle (/ˈɛkɑːrt ˈtɒlə/ EK-art TOL-ə; German: [ˈɛkhaʁt ˈtɔlə]; born Ulrich Leonard Tölle, February 16, 1948) is a German spiritual teacher and self-help author best known as the author of The Power of Now and A New Earth: Awakening to Your Life's Purpose. After being recommended by Oprah Winfrey, his first book, The Power of Now,[1] reached The New York Times Best Seller l
  • 6.5K
  • 05 Dec 2022
Topic Review
Anti-COVID-19 potential of Clove phytochemicals
The current COronaVIrus Disease 19 (COVID-19) pandemic caused by SARS-CoV-2 infection is enormously affecting the worldwide health and economy. In the wait for an effective global immunization, the development of a specific therapeutic protocol to treat COVID-19 patients is clearly necessary as a short-term solution of the problem. Drug repurposing and herbal medicine represent two of the most explored strategies for an anti-COVID-19 drug discovery. Clove (Syzygium aromaticum L.) is a well-known culinary spice that has been used for centuries in folk medicine in many disorders. Interestingly, traditional medicines have used clove since ancient times to treat respiratory ailments, whilst clove ingredients show antiviral and anti-inflammatory properties. Other interesting features are the clove antithrombotic, immunostimulatory, and antibacterial effects.
  • 6.5K
  • 13 May 2021
Topic Review
Various Attachments for Implant Overdentures
This study presents an overview of the biomechanical and biomolecular aspects of various attachments for implant overdenture. We focused on the following topics: attachment systems, retention of various attachments, stress distribution with different attachments, the design and fabrication of attachments, digital techniques in overdenture attachments, and the effects of attachments in peri-implant health. We found that plastic resin is commonly used for ball and bar attachments, whereas nylon resin is commonly used in locator attachments. The locator system offers a valuable attachment option for implant-retained overdenture. Attachment retention reduces while lateral force increases with implant inclination in overdenture. The higher the retention of an overdenture attachment, the higher the transferred stresses. Additionally, clip loading produces more stress in implants and precision elements than bar-retained dentures. As such, we conclude that the ball and locator systems the best overdenture systems due to their superior tissue response, survival rate, and patient satisfaction.
  • 6.5K
  • 03 Nov 2021
Topic Review
Peer Pressure
Peer pressure is the direct or indirect influence on people of peers, members of social groups with similar interests, experiences, or social statuses. Members of a peer group are more likely to influence a person's beliefs and behavior. A group or individual may be encouraged and want to follow their peers by changing their attitudes, values or behaviors to conform to those of the influencing group or individual. For the individual affected by peer pressure, this can result in either a positive or negative effect or both. Social groups include both membership groups in which individuals hold "formal" membership (e.g. political parties, trade unions, schools) and cliques in which membership is less clearly defined. However, a person does not need to be a member or be seeking membership of a group to be affected by peer pressure. Research suggests that organizations as well as individuals are susceptible to peer pressure. For example, a large company may be influenced by other firms in their industry or from headquarters. Peer pressure can affect individuals of all ethnicities, genders and ages. Researchers have frequently studied the effects of peer pressure on children and on adolescents, and in popular discourse the term "peer pressure" is used most often with reference to those age-groups. For children, the themes most commonly studied are their abilities for independent decision-making. For adolescents, peer pressure's relationships to sexual intercourse and substance abuse have been significantly researched. Peer pressure can be experienced through both face-to-face interaction and through digital interaction. Social media offers opportunities for adolescents and adults alike to instill and/or experience pressure every day. Studies of social networks examine connections between members of social groups, including their use of social media, to better understand mechanisms such as information sharing and peer sanctioning. Sanctions can range from subtle glances that suggest disapproval, to threats and physical violence. Peer sanctioning may enhance either positive or negative behaviors. Whether peer sanctioning will have an effect depends in part on members' expectations that possible sanctions will actually be applied. It can also depend on a person's position in a social network. Those who are more central in a social network seem more likely to be cooperative, perhaps as a result of how networks form. However, this goes both ways and so they are also more likely to participate in negative behaviors. This may be caused by the repeated social pressures they experience in their networks.
  • 6.4K
  • 07 Nov 2022
Topic Review
Alvin Plantinga's Free Will Defense
Alvin Plantinga's free will defense is a logical argument developed by American analytic philosopher Alvin Plantinga, the John A. O'Brien Professor of Philosophy Emeritus at the University of Notre Dame, and published in its final version in his 1977 book God, Freedom, and Evil. Plantinga's argument is a defense against the logical problem of evil as formulated by philosopher J. L. Mackie beginning in 1955. Mackie's formulation of the logical problem of evil argued that three attributes of God, omniscience, omnipotence, and omnibenevolence, in orthodox Christian theism are logically incompatible with the existence of evil. In 1982, Mackie conceded that Plantinga's defense successfully refuted his argument in The Miracle of Theism, though he did not claim that the problem of evil had been put to rest.
  • 6.4K
  • 18 Nov 2022
Topic Review
Nestorianism
Nestorianism is a Christian theological doctrine that upholds several distinctive teachings in the fields of Christology and Mariology. It opposes the concept of hypostatic union and emphasizes a radical distinction between two natures (human and divine) of Jesus Christ. That Christological position is defined as radical dyophisitism. Nestorianism was named after Christian theologian Nestorius (386–450), Patriarch of Constantinople from 428 to 431, who was influenced by Christological teachings of Theodore of Mopsuestia at the School of Antioch. Nestorius' teachings brought him into conflict with other prominent church leaders, most notably Cyril of Alexandria, who criticized especially his rejection of the title Theotokos ("Mother of God") for Mary, the mother of Jesus. Nestorius and his teachings were eventually condemned as heretical at the Council of Ephesus in 431, and again at the Council of Chalcedon in 451, which led to the Nestorian Schism; churches supporting Nestorian teachings broke with the rest of the Christian Church. Following that, many of Nestorius's supporters relocated to the Sasanian Empire, where they affiliated with the local Christian community, known as the Church of the East. Over the next decades the Church of the East became increasingly Nestorian in doctrine, leading to it becoming known alternatively as the Nestorian Church.
  • 6.4K
  • 25 Nov 2022
Topic Review
Nature
Nature has two inter-related meanings in philosophy and natural philosophy. On the one hand, it means the set of all things which are natural, or subject to the normal working of the laws of nature. On the other hand, it means the essential properties and causes of individual things. How to understand the meaning and significance of nature has been a consistent theme of discussion within the history of Western Civilization, in the philosophical fields of metaphysics and epistemology, as well as in theology and science. The study of natural things and the regular laws which seem to govern them, as opposed to discussion about what it means to be natural, is the area of natural science. The word "nature" derives from Latin nātūra, a philosophical term derived from the verb for birth, which was used as a translation for the earlier (pre-Socratic) Greek term phusis, derived from the verb for natural growth. Already in classical times, philosophical use of these words combined two related meanings which have in common that they refer to the way in which things happen by themselves, "naturally", without "interference" from human deliberation, divine intervention, or anything outside what is considered normal for the natural things being considered. Understandings of nature depend on the subject and age of the work where they appear. For example, Aristotle's explanation of natural properties differs from what is meant by natural properties in modern philosophical and scientific works, which can also differ from other scientific and conventional usage. Stoicism encourages practitioners to live in accordance with nature. Pyrrhonism encourages practitioners to use the guidance of nature in decision making.
  • 6.4K
  • 09 Oct 2022
Topic Review
Lexical Bundles
The term “lexical bundles” was defined as “recurrent expressions, regardless of their idiomaticity, and regardless of their structural status”. As is well documented, lexical bundles not only contribute to fluent linguistic production but also form essential building blocks of discourse. A good command of lexical bundles could be indicative of a proficient and professional academic writer and is thus considered a pivotal skill for student writers, especially EFL student writers, for achieving sustainable growth of writing competence. Appropriate use of lexical bundles in academic writing helps writers from an academic community demonstrate their research writing ability.
  • 6.4K
  • 17 Jun 2021
Topic Review
Pashtun Tahafuz Movement
The Pashtun Tahafuz Movement (Pashto: پښتون ژغورنې غورځنګ‎, Urdu: پشتون تحفظ تحریک‎; abbreviated PTM), or the Pashtun Protection Movement, is a social movement for Pashtun human rights based in Khyber Pakhtunkhwa and Balochistan. Formerly called the Mahsud Tahafuz (or Protection) Movement, it was founded in May 2014 by eight students at Gomal University, Dera Ismail Khan as an initiative for removing landmines from Waziristan and other parts of the former Federally Administered Tribal Areas, affected by the war in North-West Pakistan.
  • 6.4K
  • 24 Oct 2022
Topic Review
Koh-i-Sultan
Koh-i-Sultan is a volcano in Balochistan, Pakistan. It is part of the tectonic belt formed by the collision of India and Asia: specifically, a segment influenced by the subduction of the Arabian plate beneath the Asian plate and forming a volcanic arc which includes the Bazman and Taftan volcanoes in Iran. The volcano consists of three main cones, with heavily eroded craters running west-northwest and surrounded by a number of subsidiary volcanic centres. Its summit is 2,334 metres (7,657 ft) high, and the crater associated with the Miri cone has a smaller crater inside. The volcano is formed by andesite and dacite rocks, with fragmentary rocks prevailing over lava flows. The rocks have typical arc-volcano chemistry and composition, with a progression from andesite to dacite in the eruption products with younger age. Potassium-argon dating has indicated an age range from 5,900,000 to 90,000 years. Subsequent erosion has generated a large debris apron around the base of the volcano and carved rock formations which impressed early explorers; one well-known rock formation is Neza e Sultan. Geothermal activity and the emission of volcanic gases are ongoing, and the volcano has been prospected for the possibility of obtaining geothermal energy. The geothermal activity has resulted in widespread rock alteration and the formation of sulfur deposits, which were mentioned in a 1909 report and later mined. Koh-i-Sultan also has deposits of other minerals.
  • 6.4K
  • 04 Oct 2022
Topic Review
Battery Specifications
Batteries are the heart and the bottleneck of portable electronic systems. They power electronics and determine the system run time, with the size and volume determining factors in their design and implementation. Understanding the material properties of the battery components—anode, cathode, electrolyte, and separator—and their interaction is necessary to establish selection criteria based on their correlations with the battery metrics: capacity, current density, and cycle life. 
  • 6.4K
  • 07 Sep 2022
Topic Review
Applications of Heterocyclic Compounds
Fluorescently labelled heterocyclic compounds are useful in bioanalytical applications, including in vivo imaging, high throughput screening, diagnostics, and light-emitting diodes. These compounds have various therapeutic properties, including antifungal, antitumor, antimalarial, anti-inflammatory, and analgesic activities. Different neutral fluorescent markers containing nitrogen heterocycles (quinolones, azafluoranthenes, pyrazoloquinolines, etc.) have several electrochemical, biological, and nonlinear optic applications. Photodynamic therapy (PDT), which destroys tumors and keeps normal tissues safe, works in the presence of molecular oxygen with light and a photosensitizing drugs (dye) to obtain a therapeutic effect. 
  • 6.4K
  • 18 Oct 2022
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