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Topic Review
The Complexity of the Human–Animal Bond
The human–animal relationship is ancient, complex and multifaceted. It may have either positive effects on humans and animals or poor or even negative and detrimental effects on animals or both humans and animals. A large body of literature has investigated the beneficial effects of this relationship in which both human and animals appear to gain physical and psychological benefits from living together in a reciprocated interaction. However, analyzing the literature with a different perspective it clearly emerges that not rarely are human–animal relationships characterized by different forms and levels of discomfort and suffering for animals and, in some cases, also for people. The negative physical and psychological consequences on animals’ well-being may be very nuanced and concealed, but there are situations in which the negative consequences are clear and striking, as in the case of animal violence, abuse or neglect. Empathy, attachment and anthropomorphism are human psychological mechanisms that are considered relevant for positive and healthy relationships with animals, but when dysfunctional or pathological determine physical or psychological suffering, or both, in animals as occurs in animal hoarding.
  • 2.7K
  • 26 Oct 2022
Topic Review
Polyphenols as Antioxidant/Pro-Oxidant Compounds and Donors
Polyphenolic compounds are characterized by having at least one benzene ring with two or more hydroxyl (OH) groups. There are more than 8000 polyphenolic compounds in nature, classified into flavonoids, phenolic acids, lignans, and stilbenes.
  • 2.7K
  • 19 Sep 2023
Topic Review
Multiple Sclerosis Pathogenesis
Multiple sclerosis (MS) is predominantly an immune-mediated disease of the central nervous system (CNS) of unknown etiology with a possible genetic predisposition and effect of certain environmental factors. It is generally accepted that the disease begins with an autoimmune inflammatory reaction targeting oligodendrocytes followed by a rapid depletion of their regenerative capacity with subsequent permanent neurodegenerative changes and disability.
  • 2.7K
  • 13 Oct 2023
Topic Review
Plasmid DNA for Therapeutic Applications in Cancer
Plasmid DNA can be developed to treat different diseases, such as infections and cancer. In most cancers, the immune system is limited or suppressed, allowing cancer cells to grow. DNA vaccination has demonstrated its capacity to stimulate the immune system to fight against cancer cells.
  • 2.7K
  • 15 Sep 2022
Topic Review
Yukon Wolf
The North American wolf Canis lupus pambasileus is a subspecies of gray wolf that is called the Yukon wolf in Canada and the Alaskan Interior wolf in the United States. It is native to the Alaska Interior and Yukon, save for the tundra region of the Arctic Coast.
  • 2.7K
  • 08 Oct 2022
Topic Review
Orchid Micropropagation Using Temporary Immersion System
Temporary immersion system (TIS) overcomes the limitations of SS and liquid culture systems by temporarily submerging the plants in the liquid medium for shorter periods, followed by exposing them directly to the gaseous environment by draining the liquid medium. The shorter immersion time and more prolonged gas exposure lower the detrimental effects of hyperhydricity and asphyxia on plants, providing optimal environmental conditions for efficient nutrient absorption under the least liquid contact. Greater gas exposure improves oxygen transport to cultured cells minimizing oxygen limitation and lowering the asphyxia effect on the plant tissues in TIS. Furthermore, enhancing headspace with carbon dioxide (CO2) and culture agitation by hydrodynamic forces without mechanical devices in TIS allows normal development and increases plant tissue multiplication with regular photosynthetic activities and minor shear stress.
  • 2.7K
  • 07 Mar 2023
Topic Review
Pitch Control Technique for Horizontal Axis Wind Turbines
In recent years, the increasing environmental problems, especially the issue of global warming, have motivated demand for a cleaner, more sustainable, and economically viable energy source. In this context, wind energy plays a significant role due to the small negative impact it has on the environment, which makes it among the most widespread potential sustainable renewable fuel nowadays. However, wind turbine control systems are important factors in determining the efficiency and cost-effectiveness of a wind turbine (WT) system for wind applications.
  • 2.7K
  • 12 Oct 2023
Topic Review
Embryonic Retina Self-Organization In Vivo
Self-organization is a process that ensures histogenesis of the eye retina. The phenomenon of self-organisation is discussed in the spatiotemporal context and illustrated by key findings during vertebrate retina development in vivo and retinal regeneration in amphibians in situ. Described also are histotypic 3D structures obtained from the disaggregated retinal progenitor cells of birds and retinal 3D organoids derived from the mouse and human pluripotent stem cells.
  • 2.7K
  • 30 Jun 2022
Topic Review
Common Techniques for Biolubricant Production
Lubricants can be classified according to their physical state as solid, liquid, or semi-fluid (greases). The former is used when it is difficult to maintain contact with the fluid, while the latter is used in situations where liquid lubricants are not applicable. According to the UNE-EN 16807 standard, the term “bio” is considered synonymous with good for the environment. Its use in lubricants is linked to its environmental properties; therefore, it is expected that all compounds called bio-lubricants will degrade in the environment. 
  • 2.7K
  • 18 Sep 2023
Topic Review
3D Printing
Three-dimensional (3D) printing technology holds great potential to fabricate complex constructs in the field of regenerative medicine. Researchers in the surgical fields have used 3D printing techniques and their associated biomaterials for education, training, consultation, organ transplantation, plastic surgery, surgical planning, dentures, and more. In addition, the universal utilization of 3D printing techniques enables researchers to exploit different types of hardware and software in, for example, the surgical fields. To realize the 3D-printed structures to implant them in the body and tissue regeneration, it is important to understand 3D printing technology and its enabling technologies.
  • 2.7K
  • 20 Apr 2021
Topic Review
Emission Standard
Emission standards are the legal requirements governing air pollutants released into the atmosphere. Emission standards set quantitative limits on the permissible amount of specific air pollutants that may be released from specific sources over specific timeframes. They are generally designed to achieve air quality standards and to protect human life.
  • 2.7K
  • 29 Nov 2022
Topic Review
PEDOT:PSS Layer and Perovskite Solar Cells
Poly(3,4-ethylenedioxythiophene):poly(styrene sulfonate) (PEDOT:PSS) is the most successful conducting polymer, which has been widely used in displays, transistors, various sensors and photovoltaics (PVs). It has high optical  transparency in the visible light range and low-temperature processing condition, making it one of the most widely used polymer hole transport materials inverted perovskite solar cells (PSCs), because of its high optical transparency in the visible light range and low-temperature processing condition. However, the stability of PSCs based on pristine PEDOT:PSS is far from satisfactory, which is ascribed to the acidic and hygroscopic nature of PEDOT:PSS, and property differences between PEDOT:PSS and perovskite materials, such as conductivity, work function and surface morphology. 
  • 2.7K
  • 10 Feb 2022
Topic Review
Fique Plant in Colombia
The fique plant (Furcraea Vent.) forms part of a group of xerophytic monocotyledonous species. It belongs to the Asparagaceae family, the Agavoidea subfamily, and is native to the Andean region of South America.
  • 2.7K
  • 09 Jan 2023
Topic Review
Angiogenesis and de novo Arteriogenesis
Arteriogenesis supply oxygen and nutrients in tumor microenvironment (TME), which may play an important role in tumor growth and metastasis. Current anti-angiogenetic targeted treatments have not shown substantial clinical benefits and they are poorly tolerated, and even lead to more malignant relapse. The heterogeneity of tumor-associated endothelial cells (TAECs) and tumor vasculature may be important and should be appreciated in therapeutic targeting the TME. In this regard, the de novo arteriogenesis within the TME may be associated with tumor progression, stemness of cancer stem-like cells (CSCs) and therapeutic resistance and relapse. Targeting tumor arteriogenesis may thus be a potential novel therapeutic target. Specifically, targeting the FoxO1-CD36-Notch pathway could show the clinical potential by acting on arteriolar niche and CSCs at the same time in a variety of cancers including neuroendocrine cancers, breast cancers, lung cancers and malignant melanoma.
  • 2.7K
  • 29 Oct 2020
Topic Review
Microbe-Associated Molecular Patterns
Plants depend on both preformed and inducible defence responses to defend themselves against biotic stresses stemming from pathogen attacks. In this regard, plants perceive pathogenic threats from the environment through pattern recognition receptors (PRRs) that recognise microbe-associated molecular patterns (MAMPs), and so induce plant defence responses against invading pathogens. Close to thirty PRR proteins have been identified in plants, however, the molecular mechanisms underlying MAMP perception by these receptors/receptor complexes are not fully understood. As such, knockout (KO) of genes that code for PRRs and co-receptors / defence-associated proteins is a valuable tool to study plant immunity. The loss of gene activity often causes changes in the phenotype of the model plant, allowing in vivo studies of gene function and associated biological mechanisms. Here, we review the functions of selected PRRs, brassinosteroid insensitive 1 (BRI1) associated receptor kinase 1 (BAK1) and other associated defence proteins that have been identified in plants, and also outline KO lines generated by T-DNA insertional mutagenesis as well as the effect on MAMP perception - and triggered immunity (MTI). In addition, we further review the role of membrane raft domains in flg22-induced MTI in Arabidopsis, due to the vital role in the activation of several proteins that are part of the membrane raft domain theory in this regard.
  • 2.7K
  • 29 Oct 2020
Topic Review
Bluetooth Low Energy Mesh Networks
Bluetooth Low Energy (BLE) is an increasingly prevalent Wireless Ad-Hoc Network (WAHN) technology for battery-powered Internet of Things (IoT) devices [1]. The BLE standard was introduced by the Bluetooth Special Interest Group (SIG) in Bluetooth version 4.0, and subsequently enhanced in versions 4.2 and 5. Initially, BLE 4.x adopted the legacy Bluetooth Personal Area Network (PAN) model for multi-hop communications and the interconnection of networks. BLE 5 intends to address these inadequacies via the implementation of pure mesh topology to provide enhanced network coverage, inter-network connectivity, and improved security [2].
  • 2.7K
  • 28 Oct 2020
Topic Review
Historical Global Durum Wheat Area
Durum wheat is grown globally on 13.5 million ha in 2020/2021, which amounts to 6.2% of the wheat area. It is assumed that in the past it was more important, but the extent of that importance is unknown.
  • 2.7K
  • 13 May 2022
Topic Review
Digital-Free Tourism
Digital-free tourism (DFT) has recently attracted tourism service providers’ attention for its benefits in terms of enhancing tourists’ experiences and well-being at destinations. DFT refers to tourists who are likely to voluntarily avoid digital devices and the Internet on holiday, or travel to destinations without network signals. DFT has advantages for tourists in increasing well-being, mental health, and social networking during their journeys. DFT also has a benefit for tourism marketers in that they can consider it as a new tourism approach.
  • 2.7K
  • 01 Jun 2022
Topic Review
Psychometric Investigation of the Workplace Social Courage Scale
One such courage dimension relevant to most workplaces is social courage. Howard and colleagues created a scale for assessing social courage. The Workplace Social Courage Scale (WSCS) consists of 11 items on a 7-point Likert-type scale (1 strongly disagree to 7 strongly agree) and showed satisfactory psychometric properties in the validation study. The scale has been used to further investigate the nature of social courage.
  • 2.7K
  • 11 May 2022
Topic Review
Magnesium Forging
Interest in magnesium alloys and their applications has risen in recent years. This trend is mainly evident in casting applications, but wrought alloys are also increasingly coming into focus. Among the most common forming processes, forging is a promising candidate for the industrial production of magnesium wrought products. This overview is intended to give a general introduction into the forging of magnesium alloys and to help in the practical realization of forged products. The basics of magnesium forging practice are described and possible problems as well as material properties are discussed.
  • 2.7K
  • 10 Nov 2020
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