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Topic Review
Updates in Anticoagulation Therapy Monitoring
Anticoagulation is indicated in a broad range of clinical scenarios, including (but not limited to) the management of venous and/or arterial thromboembolism, treatment of disseminated intravascular coagulation, the flushing of lines such as in hemodialysis, cardiopulmonary bypass, or extracorporeal membrane oxygenation (ECMO).
  • 2.8K
  • 20 Apr 2021
Topic Review
Applications of Flexible Strain Sensors
Based on the ingenious design and distinguished performance of the reported flexible strain sensors, there are a great deal of applications that have been demonstrated for various occasions. The in vitro detections for human health and implantable in vivo devices for biomedical engineering, as well as human-machine interface and soft robotics applications are reviewed. 
  • 2.8K
  • 11 May 2021
Topic Review
Teachers’ Knowledge Regarding Autism
The increasing number of students with autism spectrum disorder (ASD) in mainstream education environments require teachers to know how to identify their needs, being capable to adapt their education processes and make their inclusion easier. Therefore, it is necessary that the initial and continuous training of teachers include content and skills related to the education of children with ASD. Research results carried out on this topic suggest that teachers’ knowledge of ASD is poor. It depends on the education stage (being higher in early childhood teachers and in University professors), prior training and possible prior contact with students with ASD.
  • 2.8K
  • 24 May 2021
Topic Review
Healthcare System in Romania
Within the framework of the Romanian healthcare system, a multitude of pressing challenges endure. These encompass insufficient funding, shortages of medical personnel, and ineffectiveness in the provisioning of services. These impediments substantially hinder the accessibility of healthcare services, particularly in outlying and pastoral regions, thereby rendering the system susceptible and underserving certain demographics. 
  • 2.8K
  • 03 Aug 2023
Topic Review
Index of Industry 4.0
Industry 4.0 is currently identified as a major factor in the future competitiveness of enterprises. However, the implementation and readiness of different technologies varies from one enterprise to another. Based on the performed factor analysis, an Industry 4.0 index (VPi4) was created, which allows the enterprises to determine their current level of Industry 4.0.
  • 2.8K
  • 25 Jun 2021
Topic Review
Early Follicles
Early follicles' development, especially the activation of primordial follicles, is strictly modulated by a network of signaling pathways. Recent advance in ovarian physiology has been allowed the development of several therapies to improve reproductive outcomes by manipulating early folliculogenesis. Among these, in vitro activation (IVA) has been recently developed to extend the possibility of achieving genetically related offspring for patients with premature ovarian insufficiency and ovarian dysfunction. This method was established based on basic science studies of the intraovarian signaling pathways: the phosphoinositide 3-kinase (PI3K)/Akt and the Hippo signaling pathways. These two pathways were found to play crucial roles in folliculogenesis from the primordial follicle to the early antral follicle. Following the results of rodent experiments, IVA was implemented in clinical practice. There have been multiple recorded live births and ongoing pregnancies. Further investigations are essential to confirm the efficacy and safety of IVA before used widely in clinics.
  • 2.8K
  • 27 Apr 2021
Topic Review Peer Reviewed
The Ecumene: A Research Program for Future Knowledge and Governance
The ecumene defines a beyond-border space of strong cultural encounters, flows, and merging, grounded within the traditions of world-systems, globalization, transnationalism, and cosmopolitanism discourses. Furthermore, the ecumene links directly with international regions as core political platforms in the making. As such, there are several ecumenes on the forefront, as evidenced by the literature, which can be clustered into ideal types. Epistemologically, it is a relevant concept and tool for a science-of-the-future that focuses on conviviality and transformation for the yet-to-come. Analytically, the ecumene has a descriptive, normative, and critical dimension, and can be empirically accessed through operational concepts such as triggers, hubs, and types of beyond-border conviviality. To apply the ecumene as a research program means to detect convivial common-sense spaces within the global context.
  • 2.8K
  • 04 Jun 2024
Topic Review
Frédérique Constant
Frédérique Constant SA is a Swiss manufacture of luxury wristwatches based in Plan-les-Ouates, Geneva. It was acquired in 2016 by Citizen Holdings of Tokyo, Japan. The company was established in 1988 by Peter Stas and Aletta Stas-Bax (a Dutch married couple). Before the sale to Citizen, Frédérique Constant SA was owned by Union Horlogère Holding B.V., which also owned Alpina Watches International SA, and Ateliers deMonaco SA, and was, in turn, owned by Frédérique Constant Holding SA.
  • 2.8K
  • 24 Oct 2022
Topic Review
Structural Family Therapy
Structural family therapy (SFT) is a method of psychotherapy developed by Salvador Minuchin which addresses problems in functioning within a family. Structural family therapists strive to enter, or "join", the family system in therapy in order to understand the invisible rules which govern its functioning, map the relationships between family members or between subsets of the family, and ultimately disrupt dysfunctional relationships within the family, causing it to stabilize into healthier patterns. Minuchin contends that pathology rests not in the individual, but within the family system. SFT utilizes, not only a special systems terminology, but also a means of depicting key family parameters diagrammatically. Its focus is on the structure of the family, including its various substructures. In this regard, Minuchin is a follower of systems and communication theory, since his structures are defined by transactions among interrelated systems within the family. He subscribes to the systems notions of wholeness and equifinality, both of which are critical to his notion of change. An essential trait of SFT is that the therapist actually enters, or "joins", with the family system as a catalyst for positive change. Joining with a family is a goal of the therapist early on in his or her therapeutic relationship with the family. Structural and Strategic therapy are important therapeutic models to identify as many therapists use these models as the bases for treatment. Each model has its own approach using different ways in conceptualizing a problem and developing treatment plans that support the goals stated for therapy. In addition, theory-based treatment plans are the source for goal development and treatment options by identifying the presenting problem and social influences. Both these models use similar approaches and define goals with various therapeutic processes that begin with the building of therapist and client relationship. In addition, diversity and theory are identified as a major component in choosing a theory that addresses diversity issues.
  • 2.8K
  • 28 Oct 2022
Topic Review
Tanks in France
French development into tanks began during World War I as an effort to overcome the stalemate of trench warfare, and largely at the initiative of the manufacturers. The Schneider CA1 was the first tank produced by France, and 400 units were built. The French also experimented with various tank designs, such as the Frot-Laffly landship, Boirault machine and Souain experiment. Another 400 Saint-Chamond tanks were manufactured from April 1917 to July 1918, however these tanks were largely underpowered and of limited utility due to the design of the caterpillar tracks, which were too short in comparison with the tank's length and weight. The most significant French tank development during the war was the Renault FT light tank, which set the general layout for future tank designs and was used or redesigned by various military forces, including those of the United States.
  • 2.8K
  • 03 Nov 2022
Topic Review
Radiative Transfer Equation and Diffusion Theory for Photon Transport in Biological Tissue
The RTE can mathematically model the transfer of energy as photons move inside a tissue. The flow of radiation energy through a small area element in the radiation field can be characterized by radiance [math]\displaystyle{ L(\vec{r},\hat{s},t) (\frac{W}{m^2 sr}) }[/math]. Radiance is defined as energy flow per unit normal area per unit solid angle per unit time. Here, [math]\displaystyle{ \vec{r} }[/math] denotes position, [math]\displaystyle{ \hat{s} }[/math] denotes unit direction vector and [math]\displaystyle{ t }[/math] denotes time. 
  • 2.8K
  • 16 Nov 2022
Topic Review
Polyphenols as Antioxidant/Pro-Oxidant Compounds and Donors
Polyphenolic compounds are characterized by having at least one benzene ring with two or more hydroxyl (OH) groups. There are more than 8000 polyphenolic compounds in nature, classified into flavonoids, phenolic acids, lignans, and stilbenes.
  • 2.8K
  • 19 Sep 2023
Topic Review
Radioactive Waste Containing Graphite Management
Since the beginning of the nuclear industry, graphite has been widely used as a moderator and reflector of neutrons in nuclear power reactors. Some reactors are relatively old and have already been shut down. As a result, a large amount of irradiated graphite has been generated. Although several thousand papers in the International Nuclear Information Service (INIS) database have discussed the management of radioactive waste containing graphite, knowledge of this problem is not common.
  • 2.8K
  • 17 Sep 2020
Topic Review
Human Power Production and Energy-harvesting
The maximal mechanical power produced by man, especially by large groups of people practicing sport or intense physical activity, has been proposed to be used for charge small electronic device or to partially sustain the power requirement of a gym. This practice can help to reduce carbon emissions.
  • 2.8K
  • 28 Sep 2021
Topic Review
Taro Mucilage
Taro (Colocasia esculenta) is an important source of carbohydrates as an energy source and is used as a staple food throughout the world. It is rich in mucilage and starch granules, making it a highly digestible ingredient. Mucilage can act as a matrix and a thickening, binding, emulsifying, or foaming agent in food, pharmaceutical, and several other fields of research. Moreover, mucilage can be extracted from several living organisms and has excellent functional properties, such as water-holding, oil-holding, and swelling capacities. Therefore, these remarkable functional properties make mucilage a promising ingredient with possible industrial applications. Furthermore, several extraction techniques, including enzyme-assisted, ultrasonication, microwave-assisted, aquatic, and solvent extraction methods, are used to obtain quantitative amounts of taro mucilage. Coldwater extraction with ethanol precipitation can be considered an effective and cost-effective technique to obtain high-quality mucilage with suitable industrial applications, whereas the ultrasonication method is more expensive but results in a higher amount of mucilage than other emerging techniques. Mucilage can also be used as a fat replacer or reducer, dye remover, coating agent, and antioxidating agent
  • 2.8K
  • 25 Mar 2022
Topic Review
Therapeutic Implications of Tumour Microenvironment
The tumour microenvironment (TME) comprises a complex ecosystem of different cell types, including immune cells, cells of the vasculature and lymphatic system, cancer-associated fibroblasts, pericytes, and adipocytes. Cancer proliferation, invasion, metastasis, drug resistance and immune escape are all influenced by the dynamic interaction between cancer cells and TME. Microbes, such as bacteria, fungi, viruses, archaea and protists, found within tumour tissues, constitute the intratumour microbiota, which is tumour type-specific and distinct among patients with different clinical outcomes. Growing evidence reveals a significant relevance of local microbiota in the colon, liver, breast, lung, oral cavity and pancreas carcinogenesis. Moreover, there is a growing interest in the tumour immune microenvironment (TIME) pointed out in several cross-sectional studies on the correlation between microbiota and TME. It is now known that microorganisms have the capacity to change the density and function of anticancer and suppressive immune cells, enabling the promotion of an inflammatory environment. As immunotherapy (such as immune checkpoint inhibitors) is becoming a promising therapy using TIME as a therapeutic target, the analysis and comprehension of local microbiota and its modulating strategies can help improve cancer treatments. 
  • 2.8K
  • 22 Aug 2022
Biography
Ralph Waldo Trine
Ralph Waldo Trine (October 26, 1866 – November 8, 1958) was an American philosopher, author, and teacher. He wrote many books on the New Thought movement. Trine was a close friend of Henry Ford and had several conversations with him about success in life. Born September 9, 1866,[1] in Mount Morris, Illinois,[2] Trine was the son of Samuel G. Trine and Ellen E. Newcomer.[3] He attended publi
  • 2.8K
  • 30 Nov 2022
Biography
Barry Voight
Barry Voight (/vɔɪt/; born 1937) is an American geologist, volcanologist, author, and engineer. After earning his Ph.D. at Columbia University, Voight worked as a professor of geology at several universities, including Pennsylvania State University, where he taught from 1964 until his retirement in 2005. He remains an emeritus professor there and still conducts research, focusing on rock mecha
  • 2.8K
  • 30 Dec 2022
Topic Review
Artificial Intelligence in the Agriculture
Artificial intelligence (AI) involves the development of algorithms and computational models that enable machines to process and analyze large amounts of data, identify patterns and relationships, and make predictions or decisions based on that analysis. AI has become increasingly pervasive across a wide range of industries and sectors, with healthcare, finance, transportation, manufacturing, retail, education, and agriculture are a few examples to mention. As AI technology continues to advance, it is expected to have an even greater impact on industries in the future. For instance, AI is being increasingly used in the agri-food sector to improve productivity, efficiency, and sustainability.
  • 2.8K
  • 23 May 2023
Topic Review
Small-Scale Rice Processing in Nigeria
Rice processing is an important part of Nigeria’s agricultural sector and has the potential to bring significant value to the country. Rice is a staple food in Nigeria and an important food and calorie source for the population.
  • 2.8K
  • 19 Jan 2024
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