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Topic Review
Social Inclusion in Sport for People with Disabilities
The concept and practice of social inclusion in sport are still undefined, causing confusion both in the field of sport policy and practice. According to the United Nations (UN), a conceptual and analytical work on what constitutes inclusion is needed.
  • 2.9K
  • 24 Aug 2023
Topic Review
Advances in Finger Prosthetic Mechanisms
Approximately 70% of the upper extremity amputations refers to partial hand loss with the involvement of one or more fingers. Historically, this type of limb amputation has been addressed adopting simple opposition designs that use the movement of the residual digit for grasping against a fixed device. Nevertheless, in the last few years, technological advances, and the introduction of modern computer-aided tools for the synthesis and functional design of mechanisms have led to the development of smaller, more robust systems that are constantly improving body-powered and electrically-powered prototypes.
  • 2.9K
  • 26 Oct 2020
Topic Review
Trique Language
The Triqui (/ˈtriːki/), or Trique, languages are Oto-Manguean languages of Mexico spoken by the Trique people of the state of Oaxaca and the state of Baja California (due to recent population movements). They belong to the Mixtecan branch together with the Mixtec languages and Cuicatec.
  • 2.9K
  • 21 Oct 2022
Topic Review
Natural Fibers
Natural fibers are flexible filaments extracted from renewable sources, with complex properties due to the wide variations in the chemical and structural composition of cellulose, lignin, hemicellulose, fatty acids, pectins, and other structures linked by intermolecular hydrogen bonds and forces of Van der Waals forming microfibrils with parallel arrangement.
  • 2.9K
  • 17 Nov 2021
Topic Review
GENCODE
GENCODE is a scientific project in genome research and part of the ENCODE (ENCyclopedia Of DNA Elements) scale-up project. The GENCODE consortium was initially formed as part of the pilot phase of the ENCODE project to identify and map all protein-coding genes within the ENCODE regions (approx. 1% of Human genome). Given the initial success of the project, GENCODE now aims to build an “Encyclopedia of genes and genes variants” by identifying all gene features in the human and mouse genome using a combination of computational analysis, manual annotation, and experimental validation, and annotating all evidence-based gene features in the entire human genome at a high accuracy. The result will be a set of annotations including all protein-coding loci with alternatively transcribed variants, non-coding loci with transcript evidence, and pseudogenes.
  • 2.9K
  • 08 Nov 2022
Biography
Nikolay Yegorovich Zhukovsky
Nikolay Yegorovich Zhukovsky[1] (Russian: Никола́й Его́рович Жуко́вский; January 17 [O.S. January 5] 1847 – March 17, 1921) was a Russia n scientist, mathematician and engineer, and a founding father of modern aero- and hydrodynamics. Whereas contemporary scientists scoffed at the idea of human flight, Zhukovsky was the first to undertake the study of airflow. He
  • 2.9K
  • 01 Dec 2022
Topic Review
Role of Naturally Occurring Coumarins in Plants
Coumarins are secondary plant metabolites widely distributed in higher plants, bacteria, fungi, and sponges. This great structural diversity of these natural compounds and their synthesized derivatives enables their wide range of pharmacological activities, such as antioxidant; antibacterial; antifungal; anti-human immunodeficiency infection; anti-tubercular; and anti-cancer activities. There are also many reports about their effectiveness against plant pathogenic pests (phytopathogenic fungi, bacteria, nematodes, and insects). 
  • 2.9K
  • 08 Jun 2023
Topic Review
Man-lifting Kite
right|thumb|Man-lifter War Kite designed by Samuel Franklin Cody (1867–1913).thumb|Lawrence Hargrave (seated) with his man-lifting kites in Stanwell Park, 1894. A man-lifting kite is a kite designed to lift a person from the ground. Historically, man-lifting kites have been used chiefly for reconnaissance and entertainment. Interest in their development declined with the advent of powered flight at the beginning of the 20th century.
  • 2.9K
  • 13 Oct 2022
Topic Review
Architectural Design and Structural Analysis for Steel–Glass Structures
It is well known that finite element analysis (FEA) is a powerful tool when it comes to the design and analysis of complex structures for various load combinations, including light steel curve members. FEA simulations can provide valuable insights into the behaviour of light steel curved members under different load combinations. This enables designers to optimise designs for strength, safety, and cost-effectiveness. Using two commercial 3D software programs, Rhino 7 and Strand7, to complete the FEA simulation of light steel curved members.
  • 2.9K
  • 09 Jun 2023
Topic Review
Ursa Minor
Ursa Minor, Latin for "Lesser Bear," is a constellation in the northern celestial hemisphere. It is best known for containing the North Star, Polaris, which marks the position of the north celestial pole and aids in navigation. Despite its small size and dim stars, Ursa Minor holds significant cultural and navigational importance throughout human history.
  • 2.9K
  • 15 Mar 2024
Topic Review
Factors Affecting Customers' Use of Online Banking
The online banking is a banking service that allows users to be “at home” and use the service at any time through an internet connection. In online banking services, the restrictions of time and geography have been removed, and customers can access their bank accounts and make transactions at almost anytime and anywhere via computers and an internet gateway.
  • 2.9K
  • 23 Aug 2022
Topic Review
Heterogeneous Networks
Communication technologies have drastically increased the number of wireless networks. Heterogeneous networks have now become an indispensable fact while designing the new networks and the way the data packet moves from device to device opens new challenges for transmitting the packet speedily, with maximum throughput and by consuming only confined energy. 
  • 2.9K
  • 23 Sep 2022
Topic Review
Traditionalist School
The Traditionalist School is a group of 20th- and 21st-century thinkers who believe in the existence of a perennial wisdom or perennial philosophy, primordial and universal truths which form the source for, and are shared by, all the major world religions. The principal thinkers in this tradition are René Guénon, Ananda Coomaraswamy and Frithjof Schuon. Other important thinkers in this tradition include Titus Burckhardt, Martin Lings, Jean-Louis Michon, Marco Pallis, Huston Smith, Seyyed Hossein Nasr, Jean Borella, and Julius Evola.[note 1]
  • 2.9K
  • 24 Oct 2022
Topic Review
Saman (Deity)
Saman (also called Sumana, Sumana Saman, Sinhala: සුමන සමන් දෙවි) is a deity, subject to local and indigenous belief and worship in Sri Lanka. The name Saman means "the rising morning sun". His character is of historical significance for the Sinhala people and veneration especially to all the Buddhists. God Maha Sumana Saman is depicted crowned, bejeweled, holding a lotus flower in his right or left hand and accompanied by a white elephant. According to Mahavamsa, the early chronicle of Sri Lanka, Saman is considered as one of the guardian deities of the island and Buddhism in the country. Natha, Upulvan, Vibhishana and Kataragama are the other guardian deities. Nayakkar dynasty from South India introduced the goddess Pattini replacing god Saman, during the period of Kandyan Kingdom. Saman is the guardian (patron deity) or the presiding deity of Sabaragamuwa and the Sri Pada mountain. Accordingly, his main shrine or devalaya is at Ratnapura, where an annual festival is held in his honor. Another major shrine dedicated to god Saman is situated at Mahiyangana in Uva Province of Sri Lanka. Saman is known as Samantabhadra in East Asia under the names, Pǔxián Púsà in Chinese, Fugen in Japanese, Bohyun Bosal in Korean, Kun-tu bzang-po in Tibetan and Phổ Hiền Bồ Tát in Vietnamese.
  • 2.9K
  • 21 Nov 2022
Topic Review
Molecular Mechanisms and Signaling Pathways in Gastric Cancer
Gastric cancer (GC) is common but often diagnosed late. Advances in chemotherapy, targeted therapy, and immunotherapy offer promising treatments. Perioperative chemotherapy is now the standard for resectable gastric cancer. Progress has also been made in treating metastatic disease using targeted immunotherapies. Molecular biomarkers such as programmed cell death protein ligand 1 (PD-L1), microsatellite instability (MSI), and human epidermal growth factor receptor 2 (HER2) guide personalized treatment approaches. 
  • 2.9K
  • 03 Nov 2023
Topic Review
Chasing the Elusive Luciferin
In dinoflagellates, the mechanisms related to the bioluminescent phenomenon have been well studied; however, at present, some points that remain unknown still persist. That is the case of luciferin biosynthesis, which has been reported to be an intricate process with several metabolic pathways involved. In the context of this controversial scenario, various hypotheses about the biosynthesis of luciferin in dinoflagellates are presented.
  • 2.9K
  • 05 Jan 2026
Topic Review
Preparation of Protein Oleogels
In recent years, the search for alternative routes to structure oil has gained increasing interest. Structured oils are referred to as oleogels, in which the continuous lipid phase is an edible oil, and the structuring agent forms a three-dimensional network. Such oleogels are used as a substitute for solid fats, which contain high amounts of saturated and trans fatty acids. Among available structuring agents that have been used to provide solid properties to liquid oils, protein is a more recent candidate. Due to their nutritional value and high consumer acceptance, proteins are of special interest for the preparation of edible oleogels as an alternative for solid fats. Whereas the field of protein oleogelation is still rather new and just starts unfolding, several preparation methods have been demonstrated to be suitable for protein oleogel preparation. 
  • 2.9K
  • 12 Jan 2021
Topic Review
AP-1 Transcription Factors in Myeloma
Multiple myeloma (MM) is an incurable hematologic malignancy characterized by the clonal expansion of malignant plasma cells within the bone marrow. Activator Protein-1 (AP-1) transcription factors (TFs), comprised of the JUN, FOS, ATF and MAF multigene families, are implicated in a plethora of physiologic processes and tumorigenesis including plasma cell differentiation and MM pathogenesis. Depending on the genetic background, the tumor stage, and cues of the tumor microenvironment, specific dimeric AP-1 complexes are formed. For example, AP-1 complexes containing Fra-1, Fra-2 and B-ATF play central roles in the transcriptional control of B cell development and plasma cell differentiation, while dysregulation of AP-1 family members c-Maf, c-Jun, and JunB is associated with MM cell proliferation, survival, drug resistance, bone marrow angiogenesis, and bone disease. The present review article summarizes our up-to-date knowledge on the role of AP-1 family members in plasma cell differentiation and MM pathophysiology. Moreover, it discusses novel, rationally derived approaches to therapeutically target AP-1 TFs, including protein-protein and protein-DNA binding inhibitors, epigenetic modifiers and natural products.
  • 2.9K
  • 25 May 2021
Topic Review
LPCS for Metal-Ceramic/Ceramic Coatings
Based on the recent analysis of various databases, cold spray (CS), the newest method among thermal spraying technologies, has received the unabated attention of hundreds of researchers continuously since its invention in the 1980s. The significance of CS lies in the low process temperature, which usually ensures compressive residual stresses and allows for the formation of coatings on a thermally sensitive substrate. 
  • 2.9K
  • 13 Sep 2021
Topic Review
Marine Exhaust Gas Treatment Systems
Two basic types of treatment systems of exhaust gases generated from marine compression ignition engines and from marine combustion systems, e.g., exhaust gas boilers, exist. These two basic exhaust gas treatment systems are used for SOx and particulate matter (PM) mitigation. Marine aqueous exhaust gas treatment and mainly SOx reduction systems have been commercially dominant. Since 2011, dry exhaust gas treatment and SOx mitigation systems have been commercially available from only one manufacturer. As can be realized, the main objective of both aqueous and dry exhaust gas treatment systems is the sorption and the rejection of SOx emissions from exhaust gases generated from marine combustion systems. One additional virtue of these systems is the sorption of particulate emissions of marine-generated exhaust gases, thus reducing the heavy metals, the soot, the polyaromatic hydrocarbons (PAH) and the sulfur contained in the particulate matter.
  • 2.9K
  • 02 Jun 2022
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