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Topic Review
Triangulation (Psychology)
Triangulation is a term most closely associated with the work of Murray Bowen called Family Theory. Bowen theorized that a two-person emotional system is unstable, in that under stress it forms itself into a three-person system or triangle.
  • 2.9K
  • 25 Oct 2022
Topic Review
Germplasm Resources and Distribution of Oaks in China
Oaks (Quercus spp.) are a major component of subtropical and temperate forests in the Northern Hemisphere. There are approximately 464 species, and they are dominant tree species in ecosystems. Oaks have a long history of cultivation in Europe, North America, and other continents. They are also cultivated and distributed in most provinces of China.
  • 2.9K
  • 16 Jan 2023
Topic Review
Seaweed Polysaccharide Based Products/Materials
Among the various natural polymers, polysaccharides are one of the oldest biopolymers present on the earth. They play a very crucial role in the survival of both animals and plants. Due to the presence of hydroxyl functional groups in most of the polysaccharides, it is easy to prepare their chemical derivatives. Several polysaccharide derivatives are widely used in a number of industrial applications. The polysaccharides such as cellulose, starch, chitosan, etc. have several industrial applications but due to some distinguished characteristic properties, seaweed polysaccharides are preferred in a number of applications.
  • 2.9K
  • 17 Sep 2021
Topic Review
LSPR Optical Fiber Sensors
In recent years, the interaction between light and metallic films have been proven to be a highly powerful tool for optical sensing applications. There has been continuous effort to integrate this plasmonic sensing technology using micro and nanofabrication techniques with the optical fiber sensor world, trying to get better, smaller and cost-effective high performance sensing solutions. In this work, we present a review of the latest and more relevant scientific contributions to the optical fiber sensors field using plasmonic materials over the last decade. The combination of optical fiber technology with metallic micro and nanostructures that allow plasmonic interactions have opened a complete new and promising field of study. We review the main advances in the integration of such metallic micro/nanostructures onto the optical fibers, discuss the most promising fabrication techniques and show the new trends in physical, chemical and biological sensing applications.
  • 2.9K
  • 31 May 2021
Topic Review
Glutathione-Mediated Conjugation of Anticancer Drugs
The effectiveness of many anticancer drugs depends on the creation of specific metabolites that may alter their therapeutic or toxic properties. One significant route of biotransformation is a conjugation of electrophilic compounds with reduced glutathione, which can be non-enzymatic and/or catalyzed by glutathione-dependent enzymes. Glutathione usually combines with anticancer drugs and/or their metabolites to form more polar and water-soluble glutathione S-conjugates, readily excreted outside the body. In this regard, glutathione plays a role in detoxification, decreasing the likelihood that a xenobiotic will react with cellular targets.
  • 2.9K
  • 26 Aug 2022
Topic Review
Transporters Expressed at the BBB
The blood–brain barrier (BBB) is a highly selective and restrictive semipermeable network of cells and blood vessel constituents. All components of the neurovascular unit give to the BBB its crucial and protective function, i.e., to regulate homeostasis in the central nervous system (CNS) by removing substances from the endothelial compartment and supplying the brain with nutrients and other endogenous compounds. Many transporters have been identified that play a role in maintaining BBB integrity and homeostasis. The restrictive nature of the BBB provides an obstacle for drug delivery to the CNS. Drug transporters functionally expressed on various compartments of the BBB involve numerous proteins from either the ATP-binding cassette (ABC) or the solute carrier (SLC) superfamilies. 
  • 2.9K
  • 26 May 2021
Topic Review
Flashbulb Memory
A flashbulb memory is a highly detailed, exceptionally vivid "snapshot" of the moment and circumstances in which a piece of surprising and consequential (or emotionally arousing) news was learned about. The term "flashbulb memory" suggests the surprise, indiscriminate illumination, detail, and brevity of a photograph; however flashbulb memories are only somewhat indiscriminate and are far from complete. Evidence has shown that although people are highly confident in their memories, the details of the memories can be forgotten. Flashbulb memories are one type of autobiographical memory. Some researchers believe that there is reason to distinguish flashbulb memories from other types of autobiographical memory because they rely on elements of personal importance, consequentiality, emotion, and surprise. Others believe that ordinary memories can also be accurate and long-lasting if they are highly distinctive, personally significant, or repeatedly rehearsed. Flashbulb memories have six characteristic features: place, ongoing activity, informant, own affect, other affect, and aftermath. Arguably, the principal determinants of a flashbulb memory are a high level of surprise, a high level of consequentiality, and perhaps emotional arousal.
  • 2.9K
  • 17 Nov 2022
Topic Review
Porcelain Enamel
Porcelain enamel is a glassy material deposited on a metallic substrate and fired at high temperatures (500-900 °C) to form a stable and permanent bond with it through chemical-physical reaction. This coating was developed in ancient times for decorative purposes and it was mainly used to embellish precious objects with colourful and glossy finishing as if to imitate the shining of precious stones. Only from 1760 enamelling of metal objects began to play a technical role. Nowadays vitreous enamel coatings are widely used and appreciated for high-duty technological applications, as they provide good corrosion protection of the covered substrates and they can withstand chemical attack, abrasion, and degradation caused by external agents, maintaining their aesthetical properties unchanged in time. This work is to introduce and describe the history of enamelling from ancient times to the modern era, revealing the glorious past of this material for decorative purposes and its use as a technical coating from the First Industrial Revolution onward. 
  • 2.9K
  • 27 Oct 2020
Topic Review
Aphid Transmission of Potyvirus
Potyviruses are the largest group of plant infecting RNA viruses that cause significant losses in a wide range of crops across the globe. The majority of viruses in the genus Potyvirus are transmitted by aphids in a non-persistent, non-circulative manner and have been extensively studied vis-à-vis their structure, taxonomy, evolution, diagnosis, transmission, and molecular interactions with hosts.
  • 2.9K
  • 21 Nov 2020
Topic Review
Immunotherapy in Breast Cancer
Breast cancer is a cancer that develops from breast tissue. Symptoms of breast cancer may include a breast lump, a change in the shape of the breast, sunken skin, fluid leaking from the nipple, new sunken nipple, or red or scaly patches on the skin. Distant spread may present with bone pain, swollen lymph nodes, shortness of breath, or yellowing of the skin. Breast cancer is very complex and includes several subtypes with distinct pathological features. Most of the immunotherapy efforts have focused on the most immunogenic subtypes: triple-negative breast cancer and HER2-positive breast cancer.
  • 2.9K
  • 12 Apr 2022
Biography
Peter C. Doherty
Peter Charles Doherty AC FRS FMedSci (born 15 October 1940)[1] is an Australian immunologist and Nobel laureate.[2] He received the Albert Lasker Award for Basic Medical Research in 1995, the Nobel Prize in Physiology or Medicine jointly with Rolf M. Zinkernagel[3] in 1996 and was named Australian of the Year in 1997.[4] In the Australia Day Honours of 1997, he was named a Companion of the Order
  • 2.9K
  • 08 Dec 2022
Topic Review
Digital Applications in Energy Sector
Digitalization is a transformation process which has already affected many parts of industry and society and is expected to yet increase its transformative speed and impact. In the energy sector, many digital applications have already been implemented. However, a more drastic change is expected during the next decades. Good understanding of which digital applications are possible and what are the associated benefits as well as risks from the different perspectives of the impacted stakeholders is of high importance. On the one hand, it is the basis for a broad societal and political discussion about general targets and guidelines of digitalization. On the other hand, it is an important piece of information for companies in order to develop and sustainably implement digital applications. This entry provides a structured overview of potential digital applications in the German energy (electricity) sector on the basis of a literature review.
  • 2.9K
  • 14 Apr 2021
Topic Review
Control System Design for Collaborative Robots
Human–robot collaboration is an innovative area aiming to construct an environment for safe and efficient collaboration between humans and robots to accomplish a specific task. Collaborative robots cooperate with humans to assist them in undertaking simple-to-complex tasks in several fields, including industry, education, agriculture, healthcare services, security, and space exploration. These robots play a vital role in the revolution of Industry 4.0, which defines new standards of manufacturing and the organization of products in the industry. Incorporating collaborative robots in the workspace improves efficiency, but it also introduces several safety risks.
  • 2.9K
  • 30 Jan 2023
Topic Review
Architectural Design and Structural Analysis for Steel–Glass Structures
It is well known that finite element analysis (FEA) is a powerful tool when it comes to the design and analysis of complex structures for various load combinations, including light steel curve members. FEA simulations can provide valuable insights into the behaviour of light steel curved members under different load combinations. This enables designers to optimise designs for strength, safety, and cost-effectiveness. Using two commercial 3D software programs, Rhino 7 and Strand7, to complete the FEA simulation of light steel curved members.
  • 2.9K
  • 09 Jun 2023
Topic Review
Antibiotic Susceptibility Testing
Antibiotic susceptibility testing (AST) specifies effective antibiotic dosage and formulates a profile of empirical therapy for the proper management of an individual patient’s health against deadly infections. Therefore, rapid diagnostic plays a pivotal role in the treatment of bacterial infection.
  • 2.9K
  • 03 Jan 2022
Topic Review
Entropy and Banks' Income Diversification
We collected data pertaining to Chinese listed commercial banks from 2008 to 2016 and found that the competition between banks is becoming increasingly fierce. Commercial banks have actively carried out diversification strategies for greater returns, and the financial reports show that profits are increasingly coming from the non-interest income benefits of diversification strategies. However, diversification comes with risk. We built a panel threshold model and investigated the effect of income diversification on a bank’s profitability and risk. Diversification was first measured by the Herfindahl–Hirschman index (HHI), and the results show that there is a nonlinear relationship between diversification and profitability or risk does exist. We introduced an interesting index based on the entropy to test the robustness of our model and found that a threshold effect exists in both our models, which is statistically significant. We believe the combination of the entropy index (ENTI) and the HHI enables more efficient study of the relationship between diversification and profitability or risk more efficiently. Bankers and their customers have increasingly been interested in income diversification, and they value risk as well. We suggest that banks of different sizes should adopt the corresponding diversification strategy to achieve sustainable development.
  • 2.9K
  • 02 Nov 2020
Topic Review
NF-κB
The family of NF-κB is composed of five members of proteins linking to DNA, (RelA, RelB, RelC, NFκ-B1, and NFκ-B2) that trigger a set of inflammatory downstream effectors after nuclear translocation, involved in a broad range of biological processes. Either a canonical or a non-canonical pathway can be responsible for their activation; the canonical pathway mediates inflammatory responses and leads to a rapid but transient NF-κB activation, while the non-canonical signalling is a slow, long-lasting pathway.
  • 2.9K
  • 27 Oct 2020
Topic Review
Management of Municipal Solid Waste Management
Municipal solid waste (MSW) management has become a major concern for developing countries. The physical and chemical aspects of MSW management and infrastructure need to be analyzed critically to solve the existing socio-economic problem. Depending on the socio-economic framework of a country, several MSW management procedures have been established, including landfilling, thermal treatment, and chemical treatment. Most of the MSW produced in underdeveloped and developing countries such as Bangladesh, India, and Pakistan is dumped into open landfills, severely affecting the environment. Waste-to-Energy (WTE) projects based on thermal treatments, e.g., incineration, pyrolysis, and gasification, can be feasible alternatives to conventional technologies. 
  • 2.9K
  • 26 Sep 2022
Topic Review Peer Reviewed
SARS-CoV-2 Associated Pulmonary Pathology
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel entry in the betacoronaviridae group of coronaviruses. This is the second member of this group, and the third of the family overall to emerge in the last 20 years, which has caused significant health concerns due to the clinical severity and spread of the disease it causes—coronavirus disease identified in 2019 (COVID-19). While initially emerging as a respiratory disease, and while most cases experience symptoms predominantly from this system, SARS-CoV-2 has emerged as a multisystem pathogen. From a pathomorphological point of view, the severity of changes in the respiratory system can be summed up as diffuse alveolar damage—desquamation of the alveolar epithelium with exudative and proliferative changes—pulmonary hyaline membranes, Clara cell hyperplasia, squamous cell metaplasia, and fibrosis. The second most prominent way the disease affects the lung is through endotheliitis—damage to the endothelial cells of the pulmonary vasculature, predominantly affecting the medium and large caliber blood vessels that cause the well-established clinical phenomenon of thrombosis/thromboembolism of the pulmonary vasculature. As the spread of the disease continues with the emergence of new variants and the number of cases continues to grow, including a large percentage of recurrent cases, it is essential to remember that the viral effects are not only acute but, due to the proliferative phenomena, can produce chronic sequelae. Therefore, in the background of dwindling publication interest, it is critical to focus on the histopathological aspects of the pulmonary disease, with the goal of better understanding the effects of the virus on the organism and identifying probable future complications after infection.
  • 2.9K
  • 08 Oct 2022
Topic Review
Human Schistosomiasis in Nigeria
Schistosomiasis, also known as bilharzia, is a major parasitic disease caused by blood flukes (trematode worms) of the genus Schistosoma that live in fresh waterways in tropical and subtropical zones. Over 200 million people are infected globally, 90% of whom live in sub-Saharan Africa. Nigeria has the highest burden of schistosomiasis in this region. Elimination programmes have focused on human infections, with limited attention on infections in livestock that could be transmissible to humans, i.e. zoonotic schistosomiasis. This is now recognized as a risk factor for increased transmission and recrudescence of infection of more than one schistosome species, as well as of potential hybrid variants. Members of farming communities who herd grazing cattle, goats and sheep in proximity to rivers containing Bulinus freshwater snails that are the intermediate host of asexual lifecycle stages are particularly at risk of becoming infected through daily contact with contaminated water.
  • 2.9K
  • 21 Feb 2023
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