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Topic Review
Supercapacitor
Supercapacitors are electrical devices for fast storage and release of electric energy utilizing charge accumulation in the electrochemical double layer. In terms of volumetric and gravimetric capacities they exceed conventional dielectric and electrolytic capacitors by several orders of magnitude. However, the low energy density of supercapacitors has seriously limited their wider application in many fields. Increase of energy density highly depends on development of a new generation of advanced electrode materials for supercapacitors.
  • 2.9K
  • 26 Oct 2020
Topic Review
Neelum–Jhelum Hydroelectric Project
During underground construction, the behavior of the ground is influenced by characteristics of the rock mass with situ stresses and ground water, cross section of the excavation area, excavation method, and the rate of excavation. These fundamental features are considered to ensure the support and stability of underground excavations and achieve long-term successful operation. However, the ground composition of the Himalayas hinders tunnel excavation, especially in case of mechanized tunneling; this causes time and cost overruns. This study has reviewed the recently completed Neelum–Jhelum Hydroelectric Project; the project complexities, geological environments involving significant overburden and tectonic stresses, and effects of the excavation method on tunnel stability were analyzed. 
  • 2.9K
  • 22 Mar 2021
Topic Review
Prostate Cancer Liquid Biopsy Biomarkers
Prostate cancer biomarkers can be measured in urine, blood or tissue. A variety of tests that analyse patients' biomarkers have been developed to improve diagnosis, prognosis and to help stratify individual's risk of prostate cancers. Liquid biopsy biomarkers are easy-to-use and non-invasive. They guide the decision-making process, determine whether the patient requires treatment or can be monitored under active surveillance, and help choose the best treatment option.
  • 2.9K
  • 29 Mar 2022
Topic Review
UV Filters
The use of sunscreens is a recommended practice to protect skin from solar-induced damage. Around 30 UV filters can be used in sunscreen products in the European Union. However, low photostability and putative toxicity for humans and environment have been reported for some UV filters. Therefore, it is important to develop new UV filters with improved safety profile and photostability. Over the last two decades, nearly 200 new compounds have revealed promising photoprotection properties. The explored compounds were obtained through different approaches, including exploration of natural sources, synthetic pathways, and nanotechnology. Almost 50 natural products and around 140 synthetic derivatives have been studied aiming the discovery of novel, effective, and safer future photoprotective agents. 
  • 2.9K
  • 05 May 2022
Topic Review
Extended-Spectrum β-Lactamases
The rise of antimicrobial resistance, particularly from extended-spectrum β-lactamase producing Enterobacteriaceae (ESBL-E), poses a significant global health challenge as it frequently causes the failure of empirical antibiotic therapy, leading to morbidity and mortality. The E. coli- and K. pneumoniae-derived CTX-M genotype is one of the major types of ESBL. Mobile genetic elements (MGEs) are involved in spreading ESBL genes among the bacterial population. Due to the rapidly evolving nature of ESBL-E, there is a lack of specific standard examination methods. Carbapenem has been considered the drug of first choice against ESBL-E. 
  • 2.9K
  • 07 Dec 2023
Topic Review
Civil Inattention
Civil inattention is a term in sociology coined by the sociologist Erving Goffman. It refers to the social norm of signaling awareness of others without imposing on them. In other words, when people engage in civil inattention, they acknowledge the presence of others in a public space but avoid staring or making prolonged eye contact in order to respect each other's privacy and maintain social boundaries.
  • 2.9K
  • 25 Jan 2024
Topic Review
Graphene Oxide
Graphene oxide (GO) is a chemical compound with a form similar to graphene that consists of one-atom-thick two-dimensional layers of sp2-bonded carbon. Graphene oxide exhibits high hydrophilicity and dispersibility. Thus, it is difficult to be separated from aqueous solutions. Therefore, functionalization with magnetic nanoparticles is performed in order to prepare a magnetic GO nanocomposite that combines the sufficient adsorption capacity of graphene oxide and the convenience of magnetic separation. Moreover, the magnetic material can be further functionalized with different groups to prevent aggregation and extends its potential application. Until today, a plethora of magnetic GO hybrid materials have been synthesized and successfully employed for the magnetic solid-phase extraction of organic compounds from environmental, agricultural, biological, and food samples. The developed GO nanocomposites exhibit satisfactory stability in aqueous solutions, as well as sufficient surface area. Thus, they are considered as an alternative to conventional sorbents by enriching the analytical toolbox for the analysis of trace organic compounds.
  • 2.9K
  • 15 Jan 2021
Topic Review
Gut Microbiota and Related Diseases
Dynamic interactions between gut microbiota and a host’s innate and adaptive immune systems play key roles in maintaining intestinal homeostasis and inhibiting inflammation. The gut microbiota metabolizes proteins and complex carbohydrates, synthesize vitamins, and produce an enormous number of metabolic products that can mediate cross-talk between gut epithelial and immune cells. As a defense mechanism, gut epithelial cells produce a mucosal barrier to segregate microbiota from host immune cells and reduce intestinal permeability. An impaired interaction between gut microbiota and the mucosal immune system can lead to an increased abundance of potentially pathogenic gram-negative bacteria and their associated metabolic changes, disrupting the epithelial barrier and increasing susceptibility to infections. Gut dysbiosis, or negative alterations in gut microbial composition, can also dysregulate immune responses, causing inflammation, oxidative stress, and insulin resistance. Over time, chronic dysbiosis and the translocation of bacteria and their metabolic products across the mucosal barrier may increase prevalence of type 2 diabetes, cardiovascular disease, inflammatory bowel disease, autoimmune disease, and a variety of cancers. 
  • 2.9K
  • 23 Jan 2021
Topic Review
Illegal Toxic Waste Dumping
Poor management of hazardous waste can lead to environmental pollution, injuries, and adverse health risks. Children’s exposure to hazardous waste may cause serious acute and chronic health problems due to their higher vulnerability to the toxic effects of chemicals. 
  • 2.9K
  • 24 Mar 2021
Topic Review
Bitumen and Bitumen Modification
According to the European specification (EN 12597), bitumen is defined as a virtually involatile, adhesive, and waterproofing material derived from crude oil, or present in natural asphalt, which is completely or nearly completely soluble in toluene, and very viscous or nearly solid at ambient temperatures. It is well-accepted that the original characteristics of bitumen are highly dependent on its production and processing procedure, as well as bitumen crude oil characteristics. Good crude oils and proper distillation processes can enhance bitumen properties.
  • 2.9K
  • 17 Jun 2021
Topic Review
Asymmetric Conductivity in Heavy-Fermion Metals
We consider the time reversal T and particle-antiparticle C symmetries that, being most fundamental, can be violated at microscopic level by a weak interaction. The notable example here is from condensed matter, where strongly correlated Fermi systems like HF metals and high-Tc superconductors (or HF compounds) exhibit C and T symmetries violation due to the so-called non-Fermi liquid (NFL) behavior rather than to microscopic inter-particle interaction. When a HF compound is near the topological fermion condensation quantum phase transition (FCQPT), it exhibits the NFL properties, so that the C symmetry breaks down, making the differential tunneling conductivity to be an asymmetric function of the bias voltage V. This asymmetry does not take place in normal metals, where Landau Fermi liquid (LFL) theory holds. Under the application of magnetic field, a HF compound transits to the LFL state, and σ(V) becomes symmetric function of V. These findings are in good agreement with experimental observations. We suggest that the same topological FCQPT defines the baryon asymmetry in the Universe. Thus, the most fundamental features of the nature are defined by its topological and symmetry properties.
  • 2.9K
  • 29 Apr 2021
Topic Review
Nuclear Receptor Superfamily
The nuclear receptor superfamily comprises a large group of proteins with functions essential for cell signaling, survival, and proliferation. There are multiple distinctions between nuclear superfamily classes defined by hallmark differences in function, ligand binding, tissue specificity, and DNA binding. In this review, we utilize the initial classification system, which defines subfamilies based on structure and functional difference. The defining feature of the nuclear receptor superfamily is that these proteins function as transcription factors. The loss of transcriptional regulation or gain of functioning of these receptors is a hallmark in numerous diseases. For example, in prostate cancer, the androgen receptor is a primary target for current prostate cancer therapies. Targeted cancer therapies for nuclear hormone receptors have been more feasible to develop than others due to the ligand availability and cell permeability of hormones. 
  • 2.9K
  • 12 Aug 2021
Topic Review
Decomposition Characteristics of Iron Ore during Smelting Reduction
Against the background of low global carbonization, blast furnace ironmaking technology with coking puts huge amounts of pressure on the global steel industry to save energy and reduce emissions due to its high pollution levels and high energy consumption. Bath smelting reduction technology is globally favored and studied by metallurgists as a non-blast furnace ironmaking technology that directly reduces iron ore into liquid metal without using coke as the raw material. The smelting reduction reaction of iron ore, which is the core reaction of the process, is greatly significant to its productivity and energy saving. 
  • 2.9K
  • 23 Apr 2023
Topic Review
Solidago virgaurea L
Solidago virgaurea L. (European goldenrod, Woundwort), Asteraceae, is a familiar medicinal plant in Europe and other parts of the world, widely used and among the most researched species from its genus. The aerial parts of European goldenrod have long been used for urinary tract conditions and as an anti-inflammatory agent in the traditional medicine of different peoples. Its main chemical constituents are flavonoids (mainly derived from quercetin and kaempferol), C6-C1 and C6-C3 compounds, terpenes (mostly from the essential oil), and a large number of saponin molecules (mainly virgaureasaponins and solidagosaponins). 
  • 2.9K
  • 16 Dec 2020
Topic Review
List of Intel Core I3 Microprocessors
The following is a list of Intel Core i3 brand microprocessors. These processors are designed with cheap price points, while still retaining the power of the Intel Core line. As such they (along with Intel's i5 series) are often found in laptops and low-end desktop computers.
  • 2.9K
  • 26 Oct 2022
Topic Review
Bya (Unit)
A year is the orbital period of a planetary body, for example, the Earth, moving in its orbit around the Sun. Due to the Earth's axial tilt, the course of a year sees the passing of the seasons, marked by change in weather, the hours of daylight, and, consequently, vegetation and soil fertility. In temperate and subpolar regions around the planet, four seasons are generally recognized: spring, summer, autumn and winter. In tropical and subtropical regions, several geographical sectors do not present defined seasons; but in the seasonal tropics, the annual wet and dry seasons are recognized and tracked. A calendar year is an approximation of the number of days of the Earth's orbital period, as counted in a given calendar. The Gregorian calendar, or modern calendar, presents its calendar year to be either a common year of 365 days or a leap year of 366 days, as do the Julian calendars; see below. For the Gregorian calendar, the average length of the calendar year (the mean year) across the complete leap cycle of 400 years is 365.2425 days. The ISO standard ISO 80000-3, Annex C, supports the symbol a (for Latin annus) to represent a year of either 365 or 366 days. In English, the abbreviations y and yr are commonly used. In astronomy, the Julian year is a unit of time; it is defined as 365.25 days of exactly 86,400 seconds (SI base unit), totalling exactly 31,557,600 seconds in the Julian astronomical year. The word year is also used for periods loosely associated with, but not identical to, the calendar or astronomical year, such as the seasonal year, the fiscal year, the academic year, etc. Similarly, year can mean the orbital period of any planet; for example, a Martian year and a Venusian year are examples of the time a planet takes to transit one complete orbit. The term can also be used in reference to any long period or cycle, such as the Great Year.
  • 2.9K
  • 01 Dec 2022
Topic Review
Regulation of Unmanned Aerial Vehicles
The use of unmanned aerial vehicles (UAVs) is generally regulated by the national aviation authority of the country.
  • 2.9K
  • 31 Oct 2022
Topic Review
Miracle of the Roses
Within Catholicism, a miracle of the roses is a miracle in which roses manifest an activity of God or of a saint. Such a miracle is presented in various hagiographies and legends in different forms, and it occurs in connection with diverse individuals such as Saints Elizabeth of Hungary (1207–1231), Elizabeth of Portugal (1271–1336), Saint Dorothy, a 4th-century virgin martyr at Caesarea in Cappadocia (died ca. 311), and Our Lady of Guadalupe (appeared in 1531).
  • 2.9K
  • 17 Nov 2022
Topic Review
Nanophotocatalysts
Biomedical waste management is getting significant consideration among treatment technologies, since insufficient management can cause danger to medicinal service specialists, patients, and their environmental conditions. The improvement of waste administration protocols, plans, and policies are surveyed, despite setting up training programs on legitimate waste administration for all healthcare service staff. Most biomedical waste substances do not degrade in the environment, and may also not be thoroughly removed through treatment processes. Therefore, the long-lasting persistence of biomedical waste can effectively have adverse impact on wildlife and human beings, as well. Hence, photocatalysis is gaining increasing attention for eradication of pollutants and for improving the safety and clearness of the environment due to its great potential as a green and eco-friendly process. In this regard, nanostructured photocatalysts, in contrast to their regular counterparts, exhibit significant attributes such as non-toxicity, low cost and higher absorption efficiency in a wider range of the solar spectrum, making them the best candidate to employ for photodegradation. Due to these unique properties of nanophotocatalysts for biomedical waste management, we aim to critically evaluate various aspects of these materials in the present review and highlight their importance in healthcare service settings.
  • 2.9K
  • 18 Aug 2020
Topic Review
Gut Health of Poultry
“Gut health” refers to the physical state and physiological function of the gastrointestinal tract and in the livestock system; this topic is often focused on the complex interacting components of the intestinal system that influence animal growth performance and host-microbial homeostasis.
  • 2.9K
  • 25 Jan 2022
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