Your browser does not fully support modern features. Please upgrade for a smoother experience.
Subject:
All Disciplines Arts & Humanities Biology & Life Sciences Business & Economics Chemistry & Materials Science Computer Science & Mathematics Engineering Environmental & Earth Sciences Medicine & Pharmacology Physical Sciences Public Health & Healthcare Social Sciences
Sort by:
Most Viewed Latest Alphabetical (A-Z) Alphabetical (Z-A)
Filter:
All Topic Review Biography Peer Reviewed Entry Video Entry
Topic Review
Italian Experts’ Statements on Paracetamol/Ibuprofen in Children Fever/Pain
Fever and pain are challenging symptoms in children and adolescents and are common reasons for consultations in primary care and hospital. Paracetamol and ibuprofen are currently the only recommended drugs for treating fever in Italy, but the therapeutic approaches are discrepant in the different settings.
  • 3.0K
  • 08 Nov 2021
Topic Review
Process Intensification
Process Intensification (PI) is a vast and growing area in Chemical Engineering, which deals with the enhancement of current technology to enable improved efficiency; energy, cost, and environmental impact reduction; small size & modularization; and better integration with the other equipment. Since process intensification results in novel, but complex, systems, it is necessary to rely on optimization and control techniques that can cope with such new processes. 
  • 3.0K
  • 09 Dec 2021
Topic Review
The 4 Helix Model and Tourism Social Entrepreneurships
The COVID-19 crisis has promoted innovation, support, and incentives among the four helixes, in which the STEs have benefited. As conclusions, the four helix model is functional to face the adversities of COVID-19 as long as there is planning within the entrepreneurships and the link with said model helix participants.
  • 3.0K
  • 10 Jan 2022
Topic Review
Hyperspectral Remote Sensing and Plant
Hyperspectral remote sensing provides image data with very high spectral resolution. This high resolution allows subtle differences in plant health to be recognized. Such a multidimensional data space, generated by hyperspectral sensors, has given rise to new approaches and methods for analyzing hyperspectral data.
  • 3.0K
  • 31 Jan 2022
Topic Review
Methyl Benzoate as Insecticide
The methyl benzoate is an effective pesticide against a range of different agricultural, stored product, and urban insect pests. Methyl benzoate has several important modes of action, including as a contact toxicant, a fumigant, an ovicidal toxin, an oviposition deterrent, a repellent, and an attractant.
  • 3.0K
  • 31 Mar 2022
Topic Review
Extinction
In astronomy, extinction is the absorption and scattering of electromagnetic radiation by dust and gas between an emitting astronomical object and the observer. Interstellar extinction was first documented as such in 1930 by Robert Julius Trumpler. However, its effects had been noted in 1847 by Friedrich Georg Wilhelm von Struve, and its effect on the colors of stars had been observed by a number of individuals who did not connect it with the general presence of galactic dust. For stars that lie near the plane of the Milky Way and are within a few thousand parsecs of the Earth, extinction in the visual band of frequencies (photometric system) is roughly 1.8 magnitudes per kiloparsec. For Earth-bound observers, extinction arises both from the interstellar medium (ISM) and the Earth's atmosphere; it may also arise from circumstellar dust around an observed object. Strong extinction in earth's atmosphere of some wavelength regions (such as X-ray, ultraviolet, and infrared) is overcome by the use of space-based observatories. Since blue light is much more strongly attenuated than red light, extinction causes objects to appear redder than expected, a phenomenon referred to as interstellar reddening.
  • 3.0K
  • 18 Oct 2022
Topic Review
Cassiopeia
Cassiopeia, named after the queen in Greek mythology, is a prominent constellation in the northern celestial hemisphere. Known for its distinctive "W" or "M" shape, depending on its orientation in the sky, Cassiopeia is easily recognizable and has been a subject of fascination for astronomers and stargazers throughout history.
  • 3.0K
  • 29 Feb 2024
Topic Review
Exercise and Cartilage Regeneration Therapy
In response to exercise, articular chondrocytes increase their production of glycosaminoglycans, bone morphogenic proteins, and anti-inflammatory cytokines and decrease their production of proinflammatory cytokines and matrix-degrading metalloproteinases. These changes are associated with improvements in cartilage organization and reductions in cartilage degeneration. Studies in humans indicate that exercise enhances joint recruitment of bone marrow-derived mesenchymal stem cells and upregulates their expression of osteogenic and chondrogenic genes, osteogenic microRNAs, and osteogenic growth factors. Rodent experiments demonstrate that exercise enhances the osteogenic potential of bone marrow-derived mesenchymal stem cells while diminishing their adipogenic potential, and that exercise done after stem cell implantation may benefit stem cell transplant viability. Physical exercise also exerts a beneficial effect on the skeletal system by decreasing immune cell production of osteoclastogenic cytokines interleukin-1β, tumor necrosis factor-α, and interferon-γ, while increasing their production of antiosteoclastogenic cytokines interleukin-10 and transforming growth factor-β.
  • 3.0K
  • 28 Jan 2021
Topic Review
Dragon 2
Dragon 2 is a class of reusable spacecraft developed and manufactured by U.S. aerospace manufacturer SpaceX, intended as the successor to the Dragon cargo spacecraft. The spacecraft launches atop a Falcon 9 Block 5 rocket and returns via ocean splashdown. When compared to Dragon, Crew Dragon has larger windows, new flight computers and avionics, redesigned solar arrays, and a modified outer mold line. The spacecraft has two planned variants – Crew Dragon, a human-rated capsule capable of carrying up to seven astronauts, and Cargo Dragon, an updated replacement for the original Dragon. Crew Dragon is equipped with an integrated launch escape system in a set of four side-mounted thruster pods with two SuperDraco engines each. Crew Dragon has been contracted to supply the International Space Station (ISS) with crew under the Commercial Crew Program, with the initial award occurring in October 2014 alongside Boeing CST-100 Starliner. Crew Dragon's first non-piloted test flight to the ISS launched in March 2019. Cargo Dragon will supply the ISS with cargo under the Commercial Resupply Services-2 (CRS-2) after a January 2016 selection alongside Northrop Grumman Innovation Systems' Cygnus and Sierra Nevada Corporation's Dream Chaser. SpaceX's first CRS-2 mission with the Cargo Dragon is slated to occur in August 2020 after SpaceX's final CRS-20 mission with the original Dragon spacecraft. The Crew Dragon capsule that flew in the first test flight was scheduled to be used in a flight abort test before it unexpectedly exploded during a test of its SuperDraco engines on 20 April 2019. An investigation into the explosion was completed on 15 July 2019 and resulted in changes to vehicle plumbing. The in-flight abort test was conducted on 19 January 2020 at 15:30 UTC. The first crewed launch is scheduled for April 2020.
  • 3.0K
  • 29 Nov 2022
Topic Review
Myeloid-Derived Suppressor Cells in Cancer
The emergence of immunotherapy has been an astounding breakthrough in cancer treatments. In particular, immune checkpoint inhibitors, targeting PD-1 and CTLA-4, have shown remarkable therapeutic outcomes. However, response rates from immunotherapy have been reported to be varied, with some having pronounced success and others with minimal to no clinical benefit. An important aspect associated with this discrepancy in patient response is the immune-suppressive effects elicited by the tumour microenvironment (TME). Immune suppression plays a pivotal role in regulating cancer progression, metastasis, and reducing immunotherapy success. Most notably, myeloid-derived suppressor cells (MDSC), a heterogeneous population of immature myeloid cells, have potent mechanisms to inhibit T-cell and NK-cell activity to promote tumour growth, development of the pre-metastatic niche, and contribute to resistance to immunotherapy. Accumulating research indicates that MDSC can be a therapeutic target to alleviate their pro-tumourigenic functions and immunosuppressive activities to bolster the efficacy of checkpoint inhibitors.
  • 3.0K
  • 25 May 2021
Topic Review
Ushguli in Tourism (Svaneti, Georgia)
The village community of Ushguli, located in the Upper Svaneti region in the North of Georgia, which attained UNESCO World Heritage status in 1996. Since around 2010, Ushguli has seen a step-by-step rise in tourism. Until now, it has found itself relatively unprepared to meet visitors’ interests and needs and cope with the diverse aspects of modern lifestyles.
  • 3.0K
  • 13 May 2022
Topic Review
Military Transport Aircraft
Military transport aircraft or military cargo aircraft are typically fixed wing and rotary wing cargo aircraft which are used to airlift troops, weapons and other military equipment by a variety of methods to any area of military operations around the surface of the planet, usually outside the commercial flight routes in uncontrolled airspace. Originally derived from bombers, military transport aircraft were used for delivering airborne forces during World War II and towing military gliders. Some military transport aircraft are tasked to perform multi-role duties such as aerial refueling and, rescue missions, tactical, operational and strategic airlifts onto unprepared runways, or those constructed by engineers.
  • 3.0K
  • 20 Oct 2022
Topic Review Peer Reviewed
Integrating Positive Psychology into Substance Use Treatments
Positive psychology is a rapidly expanding and recent empirical. interdisciplinary research topic (i.e., within the last 25 years). Early evidence supported that targeting positive variables (i.e., empathy or kindness) has numerous benefits, including improving health outcomes, vocational success, psychological well-being, and interpersonal connectedness. Positive Psychological Interventions (PPIs) are activities and behavioral interventions that target positive variables to promote adaptive functioning (e.g., reducing depression or promoting psychological well-being). PPIs may make excellent contributions to treating substance use, substance use disorders (SUDs), and substance use problems because the interventions can partially shift the notable negative treatment focus (e.g., avoiding the consequences of using) onto positive aspects (e.g., pursuing an ideal future). Current substance use treatment outcomes demonstrate a need for improvements (e.g., low abstinence rates and lifetime symptom remission of SUDs), and positive psychology may provide a framework for improving existing treatments. In the current paper, the author reviewed research supporting the use of PPIs in substance use treatments, provide suggestions for PPI applications, examine advantages and practical issues, outline the current limitations, and provide future directions for continuing this line of work. The author aimed to encourage researchers to advance substance use treatment improvements with positive psychology because the growing consequences from substance use (e.g., the growing frequency of accidental fatal overdose) and the variable, limited treatment outcomes, placing those who use substances in a uniquely vulnerable position.
  • 3.0K
  • 14 Sep 2023
Topic Review
Rational Vaccine Design
Vaccines are the most effective medical intervention due to their continual success in preventing infections and improving mortality worldwide. Early vaccines were developed empirically however, rational design of vaccines can allow us to optimise their efficacy, by tailoring the immune response. Establishing the immune correlates of protection greatly informs the rational design of vaccines. This facilitates the selection of the best vaccine antigens and the most appropriate vaccine adjuvant to generate optimal memory immune T cell and B cell responses. This review outlines the range of vaccine types that are currently authorised and those under development. We outline the optimal immunological correlates of protection that can be targeted. 
  • 3.0K
  • 29 Apr 2021
Topic Review
Exploiting Proteotoxic Stress in Cancer
Cancer cells typically have elevated proteotoxic stress as a result of genomic instability. The disruption of protein homeostasis causes endoplasmic reticulum stress. If not promptly managed, it could lead to a global decline in cellular function and eventual cell death[1]. This summary of review explores different protein quality control pathways and the translation of drugs targeting proteotoxic stress in haematologic cancers (using multiple myeloma as an example) versus solid cancers (using Triple Negative Breast Cancer as an example).
  • 3.0K
  • 30 Oct 2020
Biography
Avery Fisher
Avery Robert Fisher (March 4, 1906 – February 26, 1994) was an amateur violinist, pioneer in the field of sound reproduction, and founder of once prestigious Fisher Electronics. He served on the board for Lincoln Center for the Performing Arts, the New York Philharmonic, Chamber Music Society of Lincoln Center, and the Marlboro Festival. He also established the Avery Fisher Artist Program that
  • 3.0K
  • 30 Dec 2022
Topic Review
Civil Inattention
Civil inattention is a term in sociology coined by the sociologist Erving Goffman. It refers to the social norm of signaling awareness of others without imposing on them. In other words, when people engage in civil inattention, they acknowledge the presence of others in a public space but avoid staring or making prolonged eye contact in order to respect each other's privacy and maintain social boundaries.
  • 3.0K
  • 25 Jan 2024
Topic Review
IBD
Inflammatory bowel disease (IBD) continue to cause substantial morbidity and massive productivity loss globally. IBD is more common among the productive generation (age group of <30yrs) and affects their quality of life. A single mechanism responsible for IBD is difficult to determine due to the complex interplay of multiple factors including host’s genetic predisposition and environmental factors. The relapsing nature of IBD demands repeated treatment implicating a substantial financial burden to individual patients and the concerned healthcare system, especially in developing nations. This review focuses on the causes of IBD,risk factors, current treatment options and challenges, the role played by the natural products in IBD health care; and situate these natural products within the current biodiscovery research agenda, including the applications of drug discovery techniques and the search for next generation drugs to treat IBD.
  • 3.0K
  • 29 Oct 2020
Topic Review
Non-alcoholic Fraction of Beer
The present review focuses on the effects of non-alcoholic components of beer on abdominal fat, osteoporosis and body hydration in women, conditions selected for their relevance to health and aging. Although beer drinking is commonly believed to cause abdominal fat deposition, the available literature indicates this outcome is inconsistent in women. Additionally, the non-alcoholic beer fraction might improve bone health in postmenopausal women, and the effects of beer on body hydration, although still unconfirmed seem promising. Most of the health benefits of beer are due to its bioactive compounds, mainly polyphenols, which are the most studied. As alcohol-free beer also contains these compounds, it may well offer a healthy alternative to beer consumers.
  • 3.0K
  • 01 Nov 2020
Topic Review
Recovery of Palladium from the Spent Automobile Catalysts
The spent automobile catalysts (SAC) is the major secondary source of palladium and the production of SAC is increasing rapidly over years. The price of palladium keeps rising over the years, which demonstrates its preciousness and urgent industrial demand. Recovering palladium from the spent automobile catalysts benefits a lot from economic and environmental protection aspects.  Hydrometallurgical methods such as chloride leaching with oxidants possess a high selectivity of palladium and low consumption of energy, and are cost-effective and flexible for different volume feeds compared with pyrometallurgical methods. The recovery ratios of palladium and other platinum-group metals should be the focus of competition since their prices have been rapidly increased over the years, and hence more efficient extractants with high selectivity of palladium even in the complexed leachate should be proposed in the future. 
  • 3.0K
  • 12 Apr 2022
  • Page
  • of
  • 2857
Featured Entry Collections
>>

Featured Reprints

>>
Encyclopedia of Digital Society, Industry 5.0 and Smart City
Encyclopedia of Engineering
Encyclopedia of Social Sciences
Encyclopedia of Medieval Royal Iconography
Academic Video Service
Feedback