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Topic Review
AI-Based Sensor Information Fusion
In recent years, artificial intelligence (AI) and its subarea of deep learning have drawn the attention of many researchers. At the same time, advances in technologies enable the generation or collection of large amounts of valuable data (e.g., sensor data) from various sources in different applications, such as those for the Internet of Things (IoT), which in turn aims towards the development of smart cities. With the availability of sensor data from various sources, sensor information fusion is in demand for effective integration of big data.
  • 3.0K
  • 23 Aug 2021
Topic Review
CYP2E1
CYP2E1 is one of the fifty-seven cytochrome P450 genes in the human genome and is highly conserved. CYP2E1 is a unique P450 enzyme because its heme iron is constitutively in the high spin state, allowing direct reduction of, e.g., dioxygen, causing the formation of a variety of reactive oxygen species and reduction of xenobiotics to toxic products.
  • 3.0K
  • 02 Sep 2021
Topic Review
Dendrocalamus asper and Related Bamboos
Bamboos represent an emerging forest resource of economic significance and provide an avenue for sustainable development of forest resources. The development of the commercial bamboo industry is founded upon efficient molecular and technical approaches for the selection and rapid multiplication of elite germplasm for its subsequent propagation via commercial agro-forestry business enterprises. 
  • 3.0K
  • 08 Nov 2021
Topic Review
Sociological Abstraction
Sociological abstraction refers to the process of distilling and analyzing complex social phenomena by isolating and examining specific aspects or patterns. Sociologists often use abstraction as a method to simplify the study of society, allowing them to focus on key elements and relationships within social structures. By abstracting certain concepts or variables, researchers can develop theories and models that help explain and understand various social phenomena.
  • 3.0K
  • 25 Jan 2024
Topic Review
Air Temperature Forecasting
The accurate forecast of air temperature plays an important role in water resources management, land–atmosphere interaction, and agriculture. However, it is difficult to accurately predict air temperature due to its non-linear and chaotic nature. Several deep learning techniques have been proposed over the last few decades to forecast air temperature.
  • 3.0K
  • 11 Jan 2022
Topic Review
Botulinum Neurotoxin Injection for Wrinkles in Nose Region
As wrinkle removal using BoNT is being performed more often, the adverse effects, such as paralysis of the nearby muscles, diplopia, ptosis, and samurai eyebrows have been reported. When treating wrinkles with BoNT in the nasal region, significant problems, such as diplopia may result from unintended paralysis of the rectus inferior or medialis. To prevent these side effects, the injection should be administered at an anatomically accurate location of the targeting muscle, and the initial treatment should be at a reduced dosage.
  • 3.0K
  • 18 May 2022
Topic Review
Virtual Reality and Metacognition for Learning Disabilities
Learning disabilities are defined as a set of neurodevelopmental disorders of biological basis that induce cognitive abnormalities as well as symptoms related to emotional and behavioral disorders. Metacognition is defined by Drigas and Mitsea as the “set of regulatory meta-abilities and meta-skills that are consciously applied aiming at the smooth operation of the cognitive & psychophysiological mechanism as a means of achieving functional capability, self-efficacy, independent living & life satisfaction. Virtual reality (VR) is commonly regarded as a technology that induces virtual immersion in a digital world via the use of a computerized graphic simulation that allows users to immerse themselves in an interactive three-dimensional world brimming with various sensory and emotional experiences.
  • 3.0K
  • 21 Oct 2022
Topic Review
Pathophysiology of Coronary Artery Disease in Diabetes Mellitus
Diabetes mellitus (DM) significantly increases the risk of cardiovascular diseases (CVD), all-cause mortality and cardiovascular mortality. According to the Framingham study, patients with DM have a two-fold to four-fold increased risk of developing coronary artery disease (CAD) and myocardial infarction (MI) and a four-fold to six-fold increased risk of developing congestive heart failure (HF). Hyperglycemia represents the main initiating factor in the pathogenesis of diabetic complications.
  • 3.0K
  • 13 May 2022
Topic Review
MEMS Acoustic Emission Sensors
Micro-electro-mechanical-systems (MEMS) acoustic emission (AE) sensors are designed to detect active defects in materials with the transduction mechanisms of piezoresistivity, capacitance or piezoelectricity. The majority of MEMS AE sensors are designed as resonators to improve the signal-to-noise ratio. The fundamental design variables of MEMS AE sensors include resonant frequency, bandwidth/quality factor and sensitivity. Micromachining methods have the flexibility to tune the sensor frequency to a particular range, which is important, as the frequency of AE signal depends on defect modes, constitutive properties and structural composition.
  • 3.0K
  • 22 Dec 2020
Topic Review
Complementary Foods
Food safety is imperative, especially for infants and young children because of their underdeveloped immune systems. This requires adequate nutritious food with appropriate amounts of macro- and micronutrients. Currently, a well-established system for infant food is enforced by the regulatory bodies, but no clear system exists for complementary food, which is consumed by children from the age of 6 month to 24 months. As the child grows beyond 6 months, the need for nutrients increases, and if the nutritional needs are not fulfilled, it can lead to health problems, such as stunted growth, weak immune system, and cardiovascular diseases. Hence, it is important to have regulatory bodies monitoring complementary food in a similar capacity as is required for infant formula. 
  • 3.0K
  • 23 Sep 2021
Topic Review
Flowering Plant
Flowering plants are plants that bear flowers and fruits, and form the clade Angiospermae (/ˌændʒiəˈspɜːrmiː/), commonly called angiosperms. The term "angiosperm" is derived from the Greek words angeion ('container, vessel') and sperma ('seed'), and refers to those plants that produce their seeds enclosed within a fruit. They are by far the most diverse group of land plants with 64 orders, 416 families, approximately 13,000 known genera and 300,000 known species. Angiosperms were formerly called Magnoliophyta (/mæɡˌnoʊliˈɒfətə, -əˈfaɪtə/). Like gymnosperms, angiosperms are seed-producing plants. They are distinguished from gymnosperms by characteristics including flowers, endosperm within their seeds, and the production of fruits that contain the seeds. The ancestors of flowering plants diverged from the common ancestor of all living gymnosperms during the Carboniferous, over 300 million years ago, according to some genetic analyses but there is no fossil evidence for this. The closest fossil relatives of flowering plants are uncertain and contentious. The earliest angiosperm fossils are in the form of pollen around 134 million years ago during the Early Cretaceous. Over the course of the Cretaceous, angiosperms explosively diversified, becoming the dominant group of plants across the planet by the end of the period, corresponding with the decline and extinction of previously widespread gymnosperm groups. The origin and diversification of the angiosperms is often known as "Darwin's abominable mystery".
  • 3.0K
  • 09 Oct 2022
Topic Review
Culture in Maintenance Management of Public Buildings
Culture is one of the significant elements that influence the behavior of doing things the right way, without which there is a hindrance to the attainment of set goals. It has also been stated that culture is essential to maintaining public buildings, which is significant to national development. However, the level of abandonment and deterioration of public buildings is high due to a lack of culture among stakeholders in the maintenance process.
  • 3.0K
  • 08 Jun 2022
Topic Review
NK Cell Immunotherapy using Nanoparticles
Among various immunotherapies, natural killer (NK) cell cancer immunotherapy using adoptive transfer of NK cells takes a unique position by targeting tumor cells that evade the host immune surveillance. As the first-line innate effector cell, it has been revealed that NK cells have distinct mechanisms to both eliminate cancer cells directly and amplify the anticancer immune system. Over the last 40 years, NK cell cancer immunotherapy has shown encouraging reports in pre-clinic and clinic settings. In total, 288 clinical trials are investigating various NK cell immunotherapies to treat hematologic and solid malignancies in 2021. However, the clinical outcomes are unsatisfying, with remained challenges. The major limitation is attributed to the immune-suppressive tumor microenvironment (TME), low activity of NK cells, inadequate homing of NK cells, and limited contact frequency of NK cells with tumor cells. Innovative strategies to promote the cytolytic activity, durable persistence, activation, and tumor-infiltration of NK cells are required to advance NK cell cancer immunotherapy. As maturing nanotechnology and nanomedicine for clinical applications, there is a greater opportunity to augment NK cell therapeutic efficacy for the treatment of cancers. Active molecules/cytokine delivery, imaging, and physicochemical properties of nanoparticles are well equipped to overcome the challenges of NK cell cancer immunotherapy.
  • 3.0K
  • 26 Apr 2021
Topic Review
Long-Term Memory
Long-term memory (LTM) is the stage of the Atkinson–Shiffrin memory model in which informative knowledge is held indefinitely. It is defined in contrast to short-term and working memory, which persist for only about 18 to 30 seconds. Long-term memory is commonly labelled as explicit memory (declarative), as well as episodic memory, semantic memory, autobiographical memory, and implicit memory (procedural memory).
  • 3.0K
  • 24 Nov 2022
Topic Review
Biological Roles and Applications of Aconitic Acid
Aconitic acid (propene-1,2,3-tricarboxylic acid) is the most prevalent 6-carbon organic acid that accumulates in sugarcane and sweet sorghum. As a top value-added chemical, aconitic acid may function as a chemical precursor or intermediate for high-value downstream industrial and biological applications. These downstream applications include use as a bio-based plasticizer, cross-linker, and the formation of valuable and multi-functional polyesters that have also been used in tissue engineering. Aconitic acid also plays various biological roles within cells as an intermediate in the tricarboxylic acid cycle (TCA) and in conferring unique survival advantages to some plants as an antifeedant, antifungal, and means of storing fixed pools of carbon. Aconitic acid has also been reported as a fermentation inhibitor, anti-inflammatory, and a potential nematicide. 
  • 3.0K
  • 16 Mar 2022
Topic Review
PPIs' Drug Dosage Forms Development - Formulation Challenges
Proton Pump Inhibitors, also known as PPIs, belong to a group of antisecretory drugs. Since their introduction to pharmacotherapy, PPIs have been widely used in the treatment of numerous diseases manifested by excessive secretion of gastric acid. There are still unmet needs regarding their availability for patients of all age groups. Their poor stability hinders the development of formulations in which dose can be easily adjusted.
  • 3.0K
  • 31 Oct 2022
Topic Review
King Cherry
King cherry (Cerasus × nudiflora, 왕벚 wangbeoj, 왕벚나무 wangbeojnamu or 왕벚꽃 wangbeojkkoch) is a Korean native cherry tree originated from Jeju Island. It is a distinct species from Japanese native Yoshino cherry. King cherry is a rare plant and listed as an endangered species. As of April 2017, 194 King cherry trees were growing around Mt. Halla in Jeju Island. According to Gen-ichi Koidzumi, King cherry is erroneously believed to be discovered by a French missionary Emile Taquet although what he discovered was a different species. There have been disputes over the origin of king cherry and Yoshino cherry. In 2007, a study conducted on the comparison of king cherry and Yoshino cherry concluded that these trees were categorized as distinct species. However, South Korean media assert that King cherry is the same species as Yoshino cherry. In Korea most of the places for cherry blossom festivals, including Yeouido and Jinhae, are still planted with Japanese Yoshino cherry trees.
  • 3.0K
  • 01 Nov 2022
Topic Review
Smart City Industries
Smart city industries can be defined as construction businesses based on IT manufacturing (precision instruments, electrical and electronic equipment), IT services (communications and broadcasting) and knowledge services (six fields such as finance and insurance, real estate and lease, professional, scientific and technical services). 
  • 3.0K
  • 06 Sep 2021
Topic Review
Cyanidin-3-Glucoside
Cyanidin-3-glucoside (C3G) is a well-known natural anthocyanin and possesses antioxidant and anti-inflammatory properties. The catabolism of C3G in the gastrointestinal tract could produce bioactive phenolic metabolites, such as protocatechuic acid, phloroglucinaldehyde, vanillic acid, and ferulic acid, which enhance C3G bioavailability and contribute to both mucosal barrier and microbiota.
  • 3.0K
  • 02 Aug 2021
Topic Review
Humboldt Current
The Humboldt Current, also called the Peru Current, is a cold, low-salinity ocean current that flows north along the western coast of South America. It is an eastern boundary current flowing in the direction of the equator, and extends 500–1,000 km (310–620 mi) offshore. The Humboldt Current is named after the Prussian naturalist Alexander von Humboldt. In 1846, von Humboldt reported measurements of the cold-water current in his book Cosmos. The current extends from southern Chile (~45th parallel south) to northern Peru (~4th parallel south) where cold, upwelled, waters intersect warm tropical waters to form the Equatorial Front. Sea surface temperatures off the coast of Peru, around 5th parallel south, reach temperatures as low as 16 °C (61 °F). This is highly uncharacteristic of tropical waters, as most other regions have temperatures measuring above 25 °C (77 °F). Upwelling brings nutrients to the surface, which support phytoplankton and ultimately increase biological productivity. The Humboldt Current is a highly productive ecosystem. It is the most productive eastern boundary current system. It accounts for roughly 18-20% of the total worldwide marine fish catch. The species are mostly pelagic: sardines, anchovies and jack mackerel. The system's high productivity supports other important fishery resources as well as marine mammals (eared seals and cetaceans) and seabirds. Periodically, the upwelling that drives the system's productivity is disrupted by the El Niño-Southern Oscillation (ENSO) event, often with large social and economic impacts. The Humboldt has a considerable cooling influence on the climate of Chile, Peru and Ecuador. It is also largely responsible for the aridity of Atacama Desert in northern Chile and coastal areas of Peru and also of the aridity of southern Ecuador. Marine air is cooled by the current and thus is not conducive to generating precipitation (although clouds and fog are produced).
  • 3.0K
  • 07 Oct 2022
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