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Topic Review
Tools for Shoreline Change Analysis and Detection
A shoreline is the point of the physical border between land and water. While this definition looks simple, it is indeed challenging in its practical application. The position of the shoreline changes through time due to cross-shore and alongshore sediment movement in the littoral zone, and through changes in water levels. Shoreline change analysis and detection studies have progressed from using simple observation (description) from historical maps and topographical maps to employing high-resolution multi-temporal satellite images with remote sensing and Geographic Information System (GIS) approaches for a better understanding of the subject.
  • 3.2K
  • 05 May 2022
Topic Review
Agricultural Activities in the Lake Chad Region
Lake Chad is a strategic water resource shared by more than 40 million people in Sub-Saharan Africa. In the 1960s, it served as a primary source of water for irrigation and fishing in the region, but the capacity of Lake Chad to supply water for irrigation plummeted by 90% at the beginning of the twenty-first century. With some initiatives taken by the neighboring countries, Lake Chad has recovered about 5% of its water volume in recent years.
  • 3.2K
  • 18 Jul 2023
Topic Review
Synthesis of β-Lactams
Stereoselective synthesis of cis and trans β-lactams under diverse conditions is performed.  Numerous conditions are used for this study. The formation of β-lactam depends on the conditions of the experiments, structures of the imines and acid chlorides, order of addition of the reagents, reaction temperature, and solvents. A few mathematical graphs are plotted to explain the results.   
  • 3.2K
  • 25 Nov 2020
Topic Review
Four Sons of Horus
The four sons of Horus were a group of four gods in Egyptian religion, who were essentially the personifications of the four canopic jars, which accompanied mummified bodies. Since the heart was thought to embody the soul, it was left inside the body. The brain was thought only to be the origin of mucus, so it was reduced to liquid, removed with metal hooks, and discarded. This left the stomach (and small intestines), liver, large intestines, and lungs, which were removed, embalmed and stored, each organ in its own jar. There were times when embalmers deviated from this scheme: during the 21st Dynasty they embalmed and wrapped the viscera and returned them to the body, while the Canopic jars remained empty symbols. The earliest reference to the sons of Horus the Elder is found in the Pyramid Texts where they are described as friends of the king, as they assist the king in his ascension to heaven in the eastern sky by means of ladders. Their association with Horus the Elder specifically goes back to the Old Kingdom when they were said not only to be his children but also his souls. As the king, or Pharaoh was seen as a manifestation of, or especially protected by, Horus, these parts of the deceased pharaoh, referred to as the Osiris, were seen as parts of Horus, or rather, his children, an association that did not diminish with each successive pharaoh. Since Horus was their father, so Isis, Horus's original wife in the early mythological phase, was usually seen as their mother, although Hathor was also believed to be their mother, though in the details of the funerary ritual each son, and therefore each canopic jar, was protected by a particular goddess. Others say their mother was Serket, goddess of medicine and magic. Just as the sons of Horus protected the contents of a canopic jar, the king's organs, so they in turn were protected. As they were male in accordance with the principles of male/female duality their protectors were female. The classic depiction of the four sons of Horus on Middle Kingdom coffins show Imsety and Duamutef on the eastern side of the coffin and Hapi and Qebehsenuef on the western side. The eastern side is decorated with a pair of eyes and the mummy was turned on its side to face the east and the rising sun; therefore, this side is sometimes referred to as the front. The sons of Horus also became associated with the cardinal compass points, so that Hapi was the north, Imsety the south, Duamutef the east and Qebehsenuef the west. Their brother was Ihy, son of Hathor. Until the end of the 18th Dynasty the canopic jars had the head of the king, but later they were shown with animal heads. Inscriptions on coffins and sarcophagi from earliest times showed them usually in animal form.
  • 3.2K
  • 25 Oct 2022
Topic Review
ZnO and TiO2 Green Synthesis
Over the last two decades, oxide nanostructures have been continuously evaluated and used in many technological applications. The advancement of the controlled synthesis approach to design desired morphology is a fundamental key to the discipline of material science and nanotechnology. These nanostructures can be prepared via different physical and chemical methods; however, a green synthesis approach is a promising way to produce these nanostructures with desired properties with time and energy savings and/or less use of hazardous chemicals. In this regard, ZnO and TiO2 nanostructures are prominent candidates for various applications given their thermal stability, non-toxicity and cost-effective. 
  • 3.2K
  • 06 May 2021
Topic Review
Jujutsu
Jujutsu (/dʒuːˈdʒuːtsuː/ joo-JOOT-soo; Japanese: 柔術, jūjutsu listen (help·info)), also known as Jujitsu or Jiu-Jitsu, is a Japanese martial art and a method of close combat for defeating an armed and armored opponent in which one uses either a short weapon or none.
  • 3.2K
  • 30 Nov 2022
Topic Review
Anthocyanins and Vibrant Color Pigments
Anthocyanins are water-soluble vacuolar pigments that occur ubiquitously in the plant kingdom, and they are widely distributed in fruits and vegetables as glycosides, having different sugars, such as glucose, rhamnose, xylose or arabinose, attached to an aglycon nucleus. Till now have been shown to have antioxidant properties in vitro and in vivo.  This work aim to provide an up-to-date overview regarding anthocyanins as functional molecules and their chemopreventive effects on melanoma in vitro and in vivo as well as a comprehensive description of major sources of anthocyanins. Until today, numerous studies evaluated the topic of anthocyanins and various types of cancer, regarding the anthocyanins’ preventative and inhibitory effects, underlying molecular mechanisms, and such. However, there is no targeted review available regarding the anticarcinogenic effects of dietary anthocyanins on skin cancers. If diagnosed at the early stages, the survival rate of skin cancer is quite high. Nevertheless, the metastatic form has a short prognosis. In fact, the incidence of melanoma skin cancer, the type with high mortality, has increased exponentially over the last 30 years, causing the majority of skin cancer deaths. Malignant melanoma is considered a highly destructive type of skin cancer due to its particular capacity to grow and spread faster than any other type of cancers. Plants, in general, have been used in disease treatment for a long time, and medicinal plants are commonly a part of anticancer drugs on the market.
  • 3.2K
  • 23 Sep 2020
Topic Review
Blockchain Technology: Research and Applied
Blockchain being a leading technology in the 21st century is revolutionizing each sector of life. Services are being provided and upgraded using its salient features and fruitful characteristics. Businesses are being enhanced by using this technology. Countries are shifting towards digital currencies i.e., an initial application of blockchain application. It omits the need of central authority by its distributed ledger functionality. This distributed ledger is achieved by using a consensus mechanism in blockchain. A consensus algorithm plays a core role in the implementation of blockchain. Any application implementing blockchain uses consensus algorithms to achieve its desired task.
  • 3.2K
  • 09 Dec 2021
Topic Review
Enzymatic Interesterification
Enzymatic Interesterification (EIE) is the catalytic reaction that occurs when an enzyme is introduced into oil and rearranges the fatty acids on the glycerol backbone of a triglyceride. Triglycerides are either liquid or solid at room temperature. The rearrangement of the fatty acids that occurs with enzymatic interesterification provides structure and functionality to triglycerides at room temperature. This process adjusts the melting properties, increasing functionality and plasticity in food production applications. One of five different ways of altering melting property profiles, enzymatic interesterification is unlike the more widely used partial hydrogenation method in that it produces no trans fatty acids and lowers saturated fat content.
  • 3.2K
  • 12 Oct 2022
Topic Review
TRNT1 and tRNA Maturation
tRNA nucleotidyl transferase 1 (TRNT1) is an essential enzyme catalyzing the addition of terminal cytosine-cytosine-adenosine (CCA) trinucleotides to all mature tRNAs, which is necessary for aminoacylation. It was recently discovered that partial loss-of-function mutations in TRNT1 are associated with various, seemingly unrelated human diseases including sideroblastic anemia with B-cell immunodeficiency, periodic fevers, and developmental delay (SIFD), retinitis pigmentosa with erythrocyte microcytosis, and progressive B-cell immunodeficiency. In addition, even within the same disease, the severity and range of the symptoms vary greatly, suggesting a broad, pleiotropic impact of imparting TRNT1 function on diverse cellular systems. This entry describes the current state of knowledge of the TRNT1 function and the phenotypes associated with mutations in TRNT1.
  • 3.2K
  • 05 Nov 2020
Topic Review
Modulation of the Nrf2 pathways
The nuclear factor erythroid 2-related factor 2 (Nrf2) is a transcription factor that acts through antioxidant-responsive elements (ARE) in the promoter region of deoxyribonucleic acid (DNA) and it transcriptionally promotes the expression of Phase 2 metabolism/antioxidant enzymes, such as glutathione S-transferase (GST), nicotinamide adenine dinucleotide (phosphate)  (NAD(P)H) quinone oxidoreductase-1 (NQO-1), and heme oxygenase-1 (HO-1).  The Nrf2-mediated pathway is now recognized to occupy a central position in cell defense mechanisms. Here, we discuss the historical discovery of Nrf2 and the regulatory mechanism of the Nrf2-mediated pathway, focusing on the interacting proteins and post-translational modifications. 
  • 3.2K
  • 06 Sep 2020
Topic Review
Collaborationism
Collaborationism is cooperation with the enemy against one's country of citizenship in wartime. The term is most often used to describe the cooperation of civilians with the occupying Axis Powers, especially Nazi Germany, Fascist Italy, and Imperial Japan, during World War II. Motivations for collaboration by citizens and organizations included nationalism, ethnic hatred, anti-communism, antisemitism, opportunism, self-defense, or often a combination of these factors. Some collaborators in World War II committed war crimes, crimes against humanity, or atrocities such as the Holocaust. More often collaborators simply "went along to get along," attempting to benefit from the occupation or simply survive. The definition of collaborationism is imprecise and subject to interpretation. Stanley Hoffmann subdivided collaboration into involuntary (reluctant recognition of necessity) and voluntary (an attempt to exploit necessity). According to him, collaborationism can be either servile or ideological. Servile is service to an enemy based on necessity for personal survival or comfort, whereas ideological is advocacy for cooperation with an enemy power. In contrast, Bertram Gordon used the terms "collaborator" and "collaborationist" for non-ideological and ideological collaborations, respectively. James Mace Ward has asserted that, while collaboration is often equated with treason, there was "legitimate collaboration" between civilian internees (mostly Americans) in the Philippines and their Japanese captors for mutual benefit and to enhance the possibilities of the internees to survive. Collaboration with the Axis Powers in Europe and Asia existed in varying degrees in all the occupied countries. Although the United Kingdom and the United States were never occupied, a British dependency, the Channel Islands near France, was under German occupation and thousands of American civilians in Asia were interned by Japan. With the defeat of the Axis, collaborators were often punished by public humiliation, imprisonment, and execution. In France, 10,500 collaborators are estimated to have been executed, some after legal proceedings, others extrajudicially. The opposite of collaborationism in World War II was "resistance", a term which also has a broad range of meaning and interpretations.
  • 3.2K
  • 01 Dec 2022
Topic Review
The Interaction between Urban and Rural Areas
The relationships and interactions between rural and urban spaces have long been of interest to territorial sciences. However, approaches to these issues have evolved in line with the changing characteristics of the two types of territories, reflecting new relationships and structures. 
  • 3.2K
  • 26 Aug 2022
Topic Review
Core (Game Theory)
In cooperative game theory, the core is the set of feasible allocations that cannot be improved upon by a subset (a coalition) of the economy's agents. A coalition is said to improve upon or block a feasible allocation if the members of that coalition are better off under another feasible allocation that is identical to the first except that every member of the coalition has a different consumption bundle that is part of an aggregate consumption bundle that can be constructed from publicly available technology and the initial endowments of each consumer in the coalition. An allocation is said to have the core property if there is no coalition that can improve upon it. The core is the set of all feasible allocations with the core property.
  • 3.2K
  • 08 Oct 2022
Topic Review
Sankalpa
Sankalp (Sanskrit: सङ्कल्प) (alternate spellings include: sankalp, samkalpa, sankalpa, sankalpa, saṅkalpa, saṅkalpā) means an intention formed by the heart and mind -- a solemn vow, determination, or will. In practical terms, a Sankalp means a one-pointed resolve to focus both psychologically and philosophically on a specific goal. A sankalp is a tool meant to refine the will, and to focus and harmonize mind and body.
  • 3.2K
  • 20 Oct 2022
Topic Review
Indication
In medicine, an indication is a valid reason to use a certain test, medication, procedure, or surgery. There can be multiple indications to use a procedure or medication. An indication can commonly be confused with the term diagnosis. A diagnosis is the assessment that a particular [medical] condition is present while an indication is a reason for use. The opposite of an indication is a contraindication, a reason to withhold a certain medical treatment because the risks of treatment clearly outweigh the benefits. In the United States, indications for prescription drugs are approved by the FDA. Indications are included in the Indications and Usage section of the Prescribing Information. The primary role of this section of labeling is to enable health care practitioners to readily identify appropriate therapies for patients by clearly communicating the drug’s approved indication(s). The Indications and Usage section states the disease or condition, or manifestation or symptoms thereof, for which the drug is approved, as well as whether the drug is indicated for the treatment, prevention, mitigation, cure, relief, or diagnosis of that disease or condition. Additionally, the Indications and Usage section should contain the approved age groups as well as other information necessary to describe appropriate use (e.g., identifying the indicated patient/disease subgroups, stating if adjunctive therapy is required).
  • 3.2K
  • 26 Oct 2022
Topic Review
GIS Applications
A Geographic Information System (GIS) is a system designed to capture, store, manipulate, analyze, manage, and present spatial or geographic data. GIS applications are tools that allow users to create interactive queries (user-created searches), analyze spatial information, edit data in maps, and present the results of all these operations. GIS (more commonly GIScience) sometimes refers to geographic information science (GIScience), the science underlying geographic concepts, applications, and systems. Since the mid-1980s, geographic information systems have become valuable tool used to support a variety of city and regional planning functions. GIS can refer to a number of different technologies, processes, techniques and methods. It is attached to many operations and has many applications related to engineering, planning, management, transport/logistics, insurance, telecommunications, and business. For that reason, GIS and location intelligence applications can be the foundation for many location-enabled services that rely on analysis and visualization. GIS can relate unrelated information by using location as the key index variable. Locations or extents in the Earth space–time may be recorded as dates/times of occurrence, and x, y, and z coordinates representing, longitude, latitude, and elevation, respectively. All Earth-based spatial–temporal location and extent references should be relatable to one another and ultimately to a "real" physical location or extent. This key characteristic of GIS has begun to open new avenues of scientific inquiry.
  • 3.2K
  • 02 Nov 2022
Topic Review
Forensic Toxicology
Forensic toxicology is the use of toxicology and disciplines such as analytical chemistry, pharmacology and clinical chemistry to aid medical or legal investigation of death, poisoning, and drug use. The primary concern for forensic toxicology is not the legal outcome of the toxicological investigation or the technology utilized, but rather the obtainment and interpretation of results. A toxicological analysis can be done to various kinds of samples. A forensic toxicologist must consider the context of an investigation, in particular any physical symptoms recorded, and any evidence collected at a crime scene that may narrow the search, such as pill bottles, powders, trace residue, and any available chemicals. Provided with this information and samples with which to work, the forensic toxicologist must determine which toxic substances are present, in what concentrations, and the probable effect of those chemicals on the person. In the United States, forensic toxicology can be separated into 3 disciplines: Postmortem toxicology, human performance toxicology, and forensic drug testing (FDT). Postmortem toxicology includes the analysis of biological specimens taken from an autopsy to identify the effect of drugs, alcohol, and poisons. A wide range of biological specimens may be analyzed including blood, urine, gastric contents, oral fluids, hair, tissues, and more. The forensic toxicologist works with pathologists, medical examiners, and coroners to help determine the cause and manner of death. In human performance toxicology, a dose-response relationship between a drug(s) present in the body and the effects on the body are examined. This field of forensic toxicology is responsible for building and implementing laws such as driving under the influence of alcohol or drugs. Lastly, forensic drug testing (FDT) is the detection of drug use among individuals in the workplace, sport doping, drug-related probation, and new job applicant screenings. Determining the substance ingested is often complicated by the body's natural processes (see ADME), as it is rare for a chemical to remain in its original form once in the body. For example: heroin is almost immediately metabolised into another substance and further to morphine, making detailed investigation into factors such as injection marks and chemical purity necessary to confirm diagnosis. The substance may also have been diluted by its dispersal through the body; while a pill or other regulated dose of a drug may have grams or milligrams of the active constituent, an individual sample under investigation may only contain micrograms or nanograms.
  • 3.2K
  • 09 Nov 2022
Topic Review
Fuel Cell Hybrid Electric Vehicles
With the development of the global economy, the automobile industry is also developing constantly. In recent years, due to the shortage of environmental energy and other problems, seeking clean energy as the power source of vehicles to replace traditional fossil energy could be one of the measures to reduce environmental pollution. Among them, fuel cell hybrid electric vehicles (FCHEVs) have been widely studied by researchers for their advantages of high energy efficiency, environmental protection, and long driving range.
  • 3.2K
  • 08 Oct 2022
Topic Review
Adverse Possession
Adverse possession, sometimes colloquially described as "squatter's rights",[lower-alpha 1] is a legal principle that applies when a person who does not have legal title to a piece of property—usually land (real property)—attempts to claim legal ownership based upon a history of possession or occupation of the land without the permission of its legal owner. In general, a property owner has the right to recover possession of their property from unauthorized possessors through legal action such as ejectment. However, in the English common law tradition, courts have long ruled that when someone occupies a piece of property without permission and the property's owner does not exercise their right to recover their property for a significant period of time, not only is the original owner prevented from exercising their right to exclude, but an entirely new title to the property springs up in the adverse possessor. In effect, the adverse possessor becomes the property's new owner.[lower-alpha 2] Over time, legislatures have created statutes of limitations that specify the length of time that owners have to recover possession of their property from adverse possessors. In the United States, for example, these time limits vary widely between individual states, ranging from as low as five years to as many as 40 years. Although the elements of an adverse possession action are different in every jurisdiction, a person claiming adverse possession is usually required to prove non-permissive use of the property that is actual, open and notorious, exclusive, adverse, and continuous for the statutory period.[lower-alpha 3] Personal property, traditionally known as "chattel", may also be adversely possessed, but owing to the differences in the nature of real and chattel property, the rules governing such claims are rather more stringent, and favor the legal owner rather than the adverse possessor. Claims for adverse possession of chattel often involve works of art.
  • 3.2K
  • 17 Oct 2022
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