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Topic Review
Nanostrctured Anodic Oxides
Anodic oxides is part of energy conversion and storage devices.
  • 1.1K
  • 28 Sep 2021
Topic Review
Colon Carcinomas
Colon carcinomas themselves comprise over two-thirds of all colorectal cancers with an overall 5-year survival rate of 64%, which rapidly decreases to 14% when the cancer becomes metastatic. Depending on the stage of colon carcinoma at diagnosis, patients can undergo surgery to attempt complete tumor resection or move directly to chemotherapy with one or a combination of drugs. As with most cancers, colon carcinomas do not always respond to chemotherapies, so targeted therapies and immunotherapies have been developed to aid chemotherapy. We report the development of a local combination therapy for colon carcinoma whereby chemo- and immuno-therapeutic entities are delivered intratumorally to maximize efficacy and minimize off-target side effects. A hydrophobic chemotherapeutic agent, docetaxel (DTX), and cholesterol-modified Toll-like receptor 9 (TLR9) agonist CpG (cho-CpG) oligonucleotide are co-loaded in synthetic HDL (sHDL) nanodiscs. In vivo survival analysis of MC-38 tumor-bearing mice treated intratumorally with DTX-sHDL/CpG (median survival; MS = 43 days) showed significant improvement in overall survival compared to mice treated with single agents, free DTX (MS = 23 days, p <0.0001) or DTX-sHDL (MS = 28 days, p<0.0001). Two of seven mice treated with DTX-sHDL/CpG experienced complete tumor regression. None of the mice experienced any systemic toxicity as indicated by body weight maintenance and normal serum enzyme and protein levels. In summary, we have demonstrated that chemo- and immuno-therapies can be co-loaded into sHDLs, delivered locally to the tumor, and can be used to improve survival outcomes significantly compared to chemotherapy alone.
  • 1.1K
  • 29 Oct 2020
Topic Review
Modeling/Performance Analysis of Nanocarbon Interconnects
As the interconnect delay exceeds the gate delay, the integrated circuit (IC) technology has evolved from a transistor-centric era to an interconnect-centric era. Conventional metallic interconnects face several serious challenges in aspects of performance and reliability. To address these issues, nanocarbon materials, including carbon nanotube (CNT) and graphene, have been proposed as promising candidates for interconnect applications.
  • 1.1K
  • 21 Oct 2020
Topic Review
Application of Nanomaterials in Microbial Electrolysis Cells
Microbial Electrolysis Cells (MECs) are one of the bioreactors that have been used to produce bio-hydrogen by biological methods. Nanomaterials, especially when used to produce bio-hydrogen using MEC, are distinguished by their high electrical conductivity, high interaction surface area, high durability of materials, high catalytic ability to produce bio-hydrogen in MEC, biocompatibility with microorganisms and non-toxicity.
  • 1.1K
  • 06 Jan 2023
Topic Review
Fish Industry Waste and Electrochemical Energy Systems
Fish industry waste is attracting growing interest for the production of environmentally friendly materials for several different applications, due to the potential for reduced environmental impact and increased socioeconomic benefits. Recently, the application of fish industry waste for the synthesis of value-added materials and energy storage systems represents a feasible route to strengthen the overall sustainability of energy storage product lines. 
  • 1.1K
  • 06 Dec 2021
Topic Review
Nanostructured Materials for COVID-19 Prevention
The coronavirus disease 2019 (COVID-19) pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has raised great concerns about human health globally. Prevention and vaccination are still the most efficient ways to slow down the pandemic and to treat SARS-CoV-2 in various aspects.
  • 1.1K
  • 23 Dec 2022
Topic Review
Metal-Organic Frameworks in Phototherapy
The use of metal-organic frameworks (MOFs) in the biomedical field has grown significantly in recent years. Due to their distinct properties, including their porous structure, large surface area, and inherent photo-responsive properties, MOFs can be particularly useful in the fields of cancer phototherapy and immunotherapy. MOF nanoplatforms have successfully demonstrated their ability to address several drawbacks associated with cancer phototherapy and immunotherapy, enabling an effective and low-side-effect combinatorial synergistical treatment for cancer.
  • 1.1K
  • 25 Mar 2023
Topic Review
Omega-3 PUFAs and OvCa
Different strategies have been investigated for a more satisfactory treatment of advanced breast cancer, including the adjuvant use of omega-3 polyunsaturated fatty acids (PUFAs). These nutritional compounds have been shown to possess potent anti-inflammatory and antiangiogenic activities, the capacity to affect transduction pathways/receptors involved in cell growth and to reprogram tumor microenvironment. Omega-3 PUFA-containing nanoformulations designed for drug delivery in breast cancer were shown to potentiate the effects of enclosed drugs, enhance drug delivery to target sites, and minimize drug-induced side effects.
  • 1.1K
  • 03 Feb 2023
Topic Review
Three-Dimensional Printing Applications in Food Industry
Three-dimensional (3D) printing has gained increasing attention for its unique ability to create geometrically complex designs, which not only can be used for mass manufacturing but also has environmental and economic benefits. Additionally, as far as the food industry is concerned, this emerging technology has the potential to personalize products in terms of shape and/or nutritional requirements creating a wide range of food items with specially made shapes, colors, textures, tastes, and even nutrition using suitable raw materials/food components.
  • 1.1K
  • 06 Apr 2023
Topic Review
Reduction of Graphene Oxide by L-aa
The reduced form of graphene oxide (r-GO) represents a versatile precursor to obtain graphene-like materials. GO consists in a layered material based on a carbon skeleton functionalized by different oxygen-containing groups, while r-GO is obtained by the almost complete removal of  these oxygen-containing functional groups. The r-GO has mechanical, electrical, and optical properties quite similar to graphene, thus it proves to be a convenient 2D material useful for many technological applications. Consequently, the availability of effective soft-chemistry approaches based on  a green reducing agent for converting GO to r-GO are strongly needed. Among the green reductants the most suitable is the L-ascorbic acid (L-aa).
  • 1.1K
  • 13 Oct 2022
Topic Review
Nanomedicine and Brain Tumors
A brain tumor, a tumor that develops within the skull, is an abnormal mass of tissue in which cells grow and multiply out of control. Although more than 150 types of brain tumors have been reported, they are macroscopically divided into primary and metastatic groups. Tumors that arise directly from the brain tissue or surrounding the brain are classified as primary brain tumors.
  • 1.1K
  • 27 Jan 2022
Topic Review
Crystalline Carbon-Based Nanomaterials in Various Biomedical Applications
Crystalline carbon-based nanomaterials, encompassing graphene, graphene oxide, reduced graphene oxide, carbon nanotubes, and graphene quantum dots, have emerged as promising materials for the development of medical devices in various biomedical applications. These materials possess inorganic semiconducting attributes combined with organic π-π stacking features, allowing them to efficiently interact with biomolecules and present enhanced light responses.
  • 1.0K
  • 22 Aug 2023
Topic Review
Bio-Inspired Smart Nanoparticles in Oncology
Compared with traditional treatment, nanotechnology offers new therapeutic options for cancer due to its ability to selectively target and control drug release. Among the various routes of nanoparticle synthesis, plants have gained significant recognition. The tremendous potential of medicinal plants in anticancer treatments calls for a comprehensive research of existing studies on plant-based nanoparticles. The research examined various metallic nanoparticles obtained by green synthesis using medicinal plants. Plants contain biomolecules, secondary metabolites, and coenzymes that facilitate the reduction of metal ions into nanoparticles. These nanoparticles are believed to be potential antioxidants and cancer-fighting agents.
  • 1.0K
  • 02 Nov 2022
Biography
Eui-Hyeok Yang
Dr. EH Yang is a Professor in the Mechanical Engineering Department at Stevens Institute of Technology. The first to receive a MEMS Ph.D. in his native South Korea, he joined Stevens in 2006 following tenure as a senior member of the engineering staff at NASA Jet Propulsion Laboratory, where he was awarded, among other honors, the Lew Allen Award for Excellence for developing MEMS-based actuator
  • 1.0K
  • 12 Nov 2023
Topic Review
Biosensing with 2D Transition Metal Dichalcogenides Materials
There has been an exponential surge in reports on two-dimensional (2D) materials ever since the discovery of graphene in 2004. Transition metal dichalcogenides (TMDs) are a class of 2D materials where weak van der Waals force binds individual covalently bonded X–M–X layers (where M is the transition metal and X is the chalcogen), making layer-controlled synthesis possible. These individual building blocks (single-layer TMDs) transition from indirect to direct band gaps and have fascinating optical and electronic properties. Layer-dependent opto-electrical properties, along with the existence of finite band gaps, make single-layer TMDs superior to the well-known graphene that paves the way for their applications in many areas. Ultra-fast response, high on/off ratio, planar structure, low operational voltage, wafer scale synthesis capabilities, high surface-to-volume ratio, and compatibility with standard fabrication processes makes TMDs ideal candidates to replace conventional semiconductors, such as silicon, etc., in the new-age electrical, electronic, and opto-electronic devices. Besides, TMDs can be potentially utilized in single molecular sensing for early detection of different biomarkers, gas sensors, photodetector, and catalytic applications. The impact of COVID-19 has given rise to an upsurge in demand for biosensors with real-time detection capabilities. TMDs as active or supporting biosensing elements exhibit potential for real-time detection of single biomarkers and, hence, show promise in the development of point-of-care healthcare devices. 
  • 1.0K
  • 23 Feb 2023
Topic Review
Biomedical Applications of Bio-inspired Nanomaterials in Micro/Nanodevices
Exploring bio-inspired nanomaterials (BINMs) and incorporating them into micro/nanodevices represent a significant development in biomedical applications. Nanomaterials, engineered to imitate biological structures and processes, exhibit distinctive attributes such as exceptional biocompatibility, multifunctionality, and unparalleled versatility. The utilization of BINMs demonstrates significant potential in diverse domains of biomedical micro/nanodevices, encompassing biosensors, targeted drug delivery systems, and advanced tissue engineering constructs. 
  • 1.0K
  • 28 Sep 2023
Topic Review
Nanotechnological Approaches for Solubility Enhancement
Nanotechnology has the potential to revitalize both poorly performing marketed drugs and many of those pre-clinically promising candidates that were “beached” due to inadequate water solubility, in addition to novel therapeutic developments using components in the 1–100 nanometer range. As a result of developments in nanotechnology, researchers have been tackling this problem by formulating drugs with the aid of nanocarriers.
  • 1.0K
  • 05 May 2023
Topic Review
The Use of Dendrimers in Cancer Diagnosis
Dendrimers are a type of nanomaterial with unique properties, and their production can be controlled to obtain compounds with the desired characteristics. These polymeric molecules are used in cancer diagnosis and treatment through the targeted distribution of some pharmacological substances. Dendrimers have the ability to fulfill several objectives in anticancer therapy simultaneously, such as targeting tumor cells so that healthy tissue is not affected, controlling the release of anticancer agents in the tumor microenvironment, and combining anticancer strategies based on the administration of anticancer molecules to potentiate their effect through photothermal therapy or photodynamic therapy.
  • 1.0K
  • 18 May 2023
Topic Review
GO/TiO2-Related Nanocomposites as Photocatalysts in Wastewater Treatment
Photocatalysis is a more recently applied concept and is proven to be able to completely remove and degrade pollutants into simpler organic compounds. Titanium dioxide (TiO2) is a fine example of a photocatalyst owing to its cost-effectiveness and superb efficiency. However, issues such as the high recombination rate of photogenerated electrons along with positive holes while being only limited to UV irradiation need to be addressed. Carbonaceous materials such as graphene oxide (GO) can overcome such issues by reducing the recombination rate and providing a platform for adsorption accompanied by photocatalytic degradation of TiO2.
  • 1.0K
  • 28 Nov 2022
Topic Review
GD-AZO Composites
Graphene represents a new generation of materials which exhibit unique physicochemical properties such as high electron mobility, tunable optics, a large surface to volume ratio, and robust mechanical strength. These properties make graphene an ideal candidate for various optoelectronic, photonics, and sensing applications. . In recent years, numerous efforts have been focused on azobenzene polymers (AZO-polymers) as photochromic molecular switches and thermal sensors because of their light induced conformations and surface-relief structures.  However, these polymers often exhibit drawbacks like low photon storage lifetime, energy density and aggregation. These issues can be alleviated by incorporating graphene derivatives (GDs) into AZO-polymers to form orderly arranged molecules like GD-AZO composites.  
  • 1.0K
  • 11 Oct 2021
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