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Topic Review
Inner Core
The Earth's inner core is the Earth's innermost part. It is primarily a solid ball with a radius of about 1,220 kilometres (760 miles), which is about 70% of the Moon's radius. It is composed of an iron–nickel alloy and some other elements. The temperature at the inner core's surface is approximately 5,700 K (5,430 °C) or 9806 °F, which is about the temperature at the surface of the Sun.
  • 4.0K
  • 10 Nov 2022
Topic Review
Graphene Oxide-Based Anticorrosive Coatings
Graphene oxide was extensively used in the last few years due to its remarkable assets and proved to have a significant contribution to composite materials. Concerning the graphene-based coatings, the synthesis methods, protective function, anticorrosion mechanism, feasible problems, and some methods to improve the overall properties were highlighted. Regarding the contribution of the nanostructure used to improve the capability of the material, several modification strategies for graphene oxide along with the synergistic effect exhibited when functionalized with other compounds were mainly discussed.
  • 4.0K
  • 10 Dec 2020
Topic Review
Variable Speed Diesel Generators
Variable Speed Diesel Generators (VSDGs)  is a solution to optimize engine consumption and increase system efficiency during different regimes. It improves system behavior by adapting diesel generators (DGs) speed with demanded mechanical load from the generator. VSDG improves efficiency, increases engine lifetime, reduces fuel consumption, and GHG emissions. Conventional fixed speed DG can rarely operate at less than 50% of the maximal load, while VSDGs can operate for a long period at low rotational speed to support lower loads.
  • 4.0K
  • 19 Jan 2022
Topic Review
Transition Metal Dichalcogenides
In recent years, the material characteristics and properties of transition metal dichalcogenide (TMDCs) have gained research interest in various fields, such as electronics, catalytic, energy storage. In particular, many researchers have been focusing on the applications of TMDCs in dealing with environmental pollution. TMDCs provide a unique opportunity to develop higher-value applications related to environmental matters. This work highlights the applications of TMDCs contributing to pollution reduction in (i) gas sensing technology, (ii) gas adsorption and removal, (iii) wastewater treatment, (iv) fuel cleaning, and (v) carbon dioxide valorisation and conversion. Overall, the applications of TMDCs have successfully demonstrated the advantages of contributing to environmental conversation due to their special properties. The challenges and bottlenecks of implementing TMDCs in the actual industry are also highlighted. More efforts need to be devoted to overcoming the hurdles to maximize the potential of TMDCs implementation in the industry.
  • 4.0K
  • 27 Oct 2020
Topic Review
Cybersecurity Practices for Social Media Users
Cybersecurity is a collection of technologies established to protect the cyber environment of an individual user or organization. There are many cyber threats existing within the social media platform, such as loss of productivity, cyber bullying, cyber stalking, identity theft, social information overload, inconsistent personal branding, personal reputation damage, data breach, malicious software, service interruptions, hacks, and unauthorized access to social media accounts. It is also revealed that demographic factors, for example age, gender, and education level, may not necessarily be influential factors affecting the cyber awareness of the internet users.
  • 4.0K
  • 10 Feb 2022
Topic Review
Medical Ethnobotany of India
The medical ethnobotany of India is the study of Indian medicinal plants and their traditional uses. Plants have been used in India for treatment of disease and health maintenance for thousands of years, and remain important staples of health and folk medicine for millions. Indians today utilize plants for both primary medical care (principally in Rural and undeserved areas) and as supplementary treatment alongside modern medical science. It is estimated that 70% of rural Indians use traditional plant based remedies for primary healthcare needs. This reliance of plants for medicine is consistent with trends widely observed in the developing world, where between 65% and 80% of people use medicinal plant remedies. Herbal medicine in India is largely guided by folk medicine, both in codified cultural practices shared widely (Ayurveda, Siddha, Unani), and highly localized practices unique to individual tribes or tribal groups (Adivasi). Between 3,000 and 5,000 species of medicinal plants grow in India with roughly 1,000 threatened with extinction. Of these, more than 2,400 plant species have been documented for medicinal use.
  • 4.0K
  • 01 Nov 2022
Topic Review
Sulfolobus Solfataricus
Saccharolobus solfataricus is a species of thermophilic archaeon. It was transferred from the genus Sulfolobus to the new genus Saccharolobus with the description of Saccharolobus caldissimus in 2018. It was first isolated and discovered in the Solfatara volcano (which it was subsequently named after) in 1980 by two Germans microbiologists Karl Setter and Wolfram Zillig, in Solfatara volcano (Pisciarelli-Campania, Italy). However, these organisms are not isolated to volcanoes but are found all over the world in places such as hot springs. The species grows best in temperatures around 80° Celsius, a pH level between 2 and 4, and enough sulfur for solfataricus to metabolize in order to gain energy. These conditions qualify it as an extremophile and it is specifically known as a thermoacidophile because of its preference to high temperatures and low pH levels and it is also in aerobic and heterotropic categories for its metabolic system. It usually has a spherical cell shape and it makes frequent lobes. Being an autotroph it receives energy from growing on sulfur or even a variety of organic compounds. Currently, it is the most widely studied organism that is within the Crenarchaeota branch. Solfataricus are researched for their methods of DNA replication, cell cycle, chromosomal integration, transcription, RNA processing, and translation. All the data points to the organism having a large percent of archaeal-specific genes, which showcases the differences between the three types of microbes: archaea, bacteria, and eukarya.
  • 4.0K
  • 04 Nov 2022
Topic Review
Lysosomal-Cleavable Peptide Linkers in Antibody–Drug Conjugates
Antibody–drug Conjugates (ADCs) are a powerful therapeutic modality for cancer treatment. ADCs are multi-functional biologics in which a disease-targeting antibody is conjugated to an effector payload molecule via a linker. The success of currently used ADCs has been largely attributed to the development of linker systems, which allow for the targeted release of cytocidal payload drugs inside cancer cells.
  • 4.0K
  • 02 Feb 2024
Topic Review
Laser Forming Process
Laser forming is an emerging manufacturing process capable of producing either uncomplicated and complicated shapes by employing a concentrated heating source. The heat source movement creates local softening, and a plastic strain will be induced during the rise of temperature and the subsequent cooling. This contactless forming process may be used for the simple bending of sheets and tubes or fabrication of doubly-curved parts. Different studies have been carried out over recent years to understand the mechanism of forming and predicting the bending angle. The analysis of process parameters and search for optimized manufacturing conditions are among the most discussed topics. This review describes the main recent findings in the laser forming of single and multilayer sheets, composite and fiber-metal laminate plates, force assisted laser bending, tube bending by laser beam, the optimization technique implemented for process parameters selection and control, doubly-curved parts, and the analytical solutions in laser bending. The main focus is set to the researches published since 2015.
  • 4.0K
  • 21 Nov 2020
Topic Review
Cold Atmospheric Pressure Plasma Technology
Cold atmospheric pressure plasma (CAPP) technology has received substantial attention due to its valuable properties including operational simplicity, low running cost, and environmental friendliness. Several different gases (air, nitrogen, helium, argon) and techniques (corona discharge, dielectric barrier discharge, plasma jet) can be used to generate plasma at atmospheric pressure and low temperature. Plasma treatment is routinely used in materials science to modify the surface properties (e.g., wettability, chemical composition, adhesion) of a wide range of materials (e.g., polymers, textiles, metals, glasses). Moreover, CAPP seems to be a powerful tool for the inactivation of various pathogens (e.g., bacteria, fungi, viruses) in the food industry (e.g., food and packing material decontamination, shelf life extension), agriculture (e.g., disinfection of seeds, fertilizer, water, soil) and medicine (e.g., sterilization of medical equipment, implants). Plasma medicine also holds great promise for direct therapeutic treatments in dentistry (tooth bleaching), dermatology (atopic eczema, wound healing) and oncology (melanoma, glioblastoma).
  • 4.0K
  • 10 Jun 2021
Topic Review
H Bridge
An H bridge is an electronic circuit that switches the polarity of a voltage applied to a load. These circuits are often used in robotics and other applications to allow DC motors to run forwards or backwards. Most DC-to-AC converters (power inverters), most AC/AC converters, the DC-to-DC push–pull converter, most motor controllers, and many other kinds of power electronics use H bridges. In particular, a bipolar stepper motor is almost invariably driven by a motor controller containing two H bridges.
  • 4.0K
  • 24 Oct 2022
Topic Review
Layered Double Hydroxides
Layered double hydroxides (LDHs) are anionic clays which have found applications in a wide range of fields, including medicine (especially in drug delivery and release), environment (to remediate pollution), biotechnology, as precursors for catalysts, and in electrochemical applications (electrocatalysts, sensors, oxygen evolution reaction (OER), energy storage, fuel cells, etc.). To be used in electrochemistry  they should possess electrical conductivity which can be ensured by the presence of metals able to give reversible redox reactions in a proper potential window. The metal centers can act as redox mediators to catalyze reactions for which the required overpotential is too high, and this is a key aspect for the development of processes and devices where the control of charge transfer reactions plays an important role.
  • 4.0K
  • 30 Mar 2021
Topic Review
Personal Values in Learning Approaches
Personal values play a significant role when adopting learning approaches by individuals during their studies. Particularly in higher education, these values significantly influence the character that individuals play within their learning community and ultimately influence their academic achievements. The purpose of this paper is to investigate personal values in their choice of learning approaches and, subsequently, how it impacts one’s academic achievements.
  • 4.0K
  • 21 Jul 2021
Topic Review
Compensatory Carry-Over Action Model (CCAM)
The Compensatory Carry-Over Action Model (CCAM) is innovative as most behavioral theories only model single activity. The CCAM, however, models different single activities—such as physical activity and nutrition —and how they change as a result of one another. Such lifestyle activities are assumed to be formed by higher-level goals, which can drive activity volitionally or unconsciously, and are rather unspecific. They become specific because of activities that are subjectively seen as leading to this goal. Each activity must be intended, pursued, and controlled. Specific resources ensure that individuals have the chance to translate their intentions into activity and that they resist distractors. Compensation and transfer (also called carry-over) operate between the different activities. If people devote all of their energy to one domain and believe that no resources remain for the other activity, compensation can help to attain goals. It is also possible that an individual successfully performs one activity, and existing or developing resources may be transferred to another activity.
  • 4.0K
  • 16 Dec 2020
Topic Review
AlCr-Based Coatings in Industrial Applications
AlCr-based hard nitride coatings with different chemical compositions and architectures have been successfully developed and applied over the last few decades. Coating properties are mainly influenced by deposition conditions and the Al/Cr content. The fcc structure is dominant for an Al-content up to Al0.7Cr0.3N and is preferred for most cutting applications. Different (AlCrX)N alloying concepts, including X = Si, W, B, V, have been investigated in order to enhance oxidation resistance and wear behaviour and to provide tribological properties. AlCr-based oxynitrides and even pure oxides (Al1−xCrx)2O3 with different crystalline structures have been explored. Multi- and nanolayered coatings within the AlCr materials system, as well as in combination with (TiSi)N, for example, have also been implemented industrially. The dominant deposition technology is the vacuum arc process. Recently, advanced high-power impulse magnetron sputtering (HiPIMS) processes have also been successfully applied on an industrial scale. 
  • 4.0K
  • 25 Mar 2021
Topic Review
Inflammatory Cytokines Induce Melanogenesis
The production of melanin pigments by melanocytes and their quantity, quality, and distribution play a decisive role in determining human skin, eye, and hair color, and protect the skin from adverse effects of ultraviolet radiation (UVR) and oxidative stress from various environmental pollutants. Melanocytes reside in the basal layer of the interfollicular epidermis and are compensated by melanocyte stem cells in the follicular bulge area. Various stimuli such as eczema, microbial infection, ultraviolet light exposure, mechanical injury, and aging provoke skin inflammation. These acute or chronic inflammatory responses cause inflammatory cytokine production from epidermal keratinocytes as well as dermal fibroblasts and other cells, which in turn stimulate melanocytes, often resulting in skin pigmentation. It is confirmed by some recent studies that several interleukins (ILs) and other inflammatory mediators modulate the proliferation and differentiation of human epidermal melanocytes and also promote or inhibit expression of melanogenesis-related gene expression directly or indirectly, thereby participating in regulation of skin pigmentation. Understanding of mechanisms of skin pigmentation due to inflammation helps to elucidate the relationship between inflammation and skin pigmentation regulation and can guide development of new therapeutic pathways for treating pigmented dermatosis. 
  • 4.0K
  • 07 May 2021
Topic Review Peer Reviewed
Chytrids in Soil Environments: Unique Adaptations and Distributions
Chytridiomycota (zoosporic true fungi) have a consistent presence in soils and have been frequently identified within many diverse terrestrial environments. However, Chytridiomycota and other early-diverging fungi have low representation in whole-genome sequencing databases compared to Dikarya. New molecular techniques have provided insights into the diversity and abundance of chytrids in soils and the changes in their populations both spatially and temporally. Chytrids complete their life cycle within rapidly changing soil environments where they may be more common within micropores due to protection from predation, desiccation, and extreme temperatures. Reproductive and morphological changes occur in response to environmental changes including pH, fluctuating nutrient concentrations, and metals at levels above toxic thresholds. Rhizoids share some features of hyphae, including the spatial regulation of branching and the ability to attach, adapt to, and proliferate in different substrates, albeit on a microscale. Soil chytrids provide a pool of novel enzymes and proteins which enable a range of lifestyles as saprotrophs or parasites, but also can be utilised as alternative tools with some biotechnological applications. Thus, 3D live-cell imaging and micromodels such as MicroCT may provide insight into zoospore functions and rhizoid plasticity, respectively, in response to various conditions. A combination of classical techniques of soil chytrid baiting with simultaneous molecular and ecological data will provide insights into temporal population changes in response to environmental change. The authors emphasise the need to review and improve DNA-based methodologies for identifying and quantifying chytrids within the soil microbiome to expand our knowledge of their taxonomy, abundance, diversity, and functionality within soil environments.
  • 4.0K
  • 22 May 2023
Topic Review
Electrode Passivation
The main reason for electrode passivation is adsorption/deposition of a passivating compound on working electrode surface. The most pronounced consequences are the decrease of the rate of electrode reaction resulting in the shift of half-wave or peak potential to more negative (in the case of cathodic reaction) or to more positive (in the case of anodic reaction) potentials and in the decrease of peak current, which is especially in the case of pulsed technique influenced by this rate. 
  • 4.0K
  • 22 Feb 2021
Topic Review
Social Constructionism
Social constructionism is a theoretical approach in sociology that posits that reality is socially constructed through language, discourse, and social interactions. It asserts that knowledge and meaning are not inherent in objects or phenomena but are instead created and maintained by individuals and societies through shared beliefs, cultural norms, and power dynamics. Social constructionism emphasizes the role of language, symbols, and social context in shaping our understanding of reality and social phenomena.
  • 4.0K
  • 26 Jan 2024
Topic Review
Dissociated Optic Nerve Fiber Layer
Dissociated optic nerve fiber layer (DONFL) appearance is characterized by dimpling of the fundus when observed after vitrectomy with the internal limiting membrane (ILM) peeling in macular diseases. However, the cause of DONFL remains largely unknown. Optical coherence tomography (OCT) findings have indicated that the nerve fiber layer (NFL) and ganglion cells are likely to have been damaged in patients with DONFL appearance. Since DONFL appearance occurs at a certain postoperative period, it is unlikely to be retinal damage directly caused by ILM peeling because apoptosis occurs at a certain period after tissue damage and/or injury. However, it may be due to ILM peeling-induced apoptosis in the retinal tissue. Anoikis is a type of apoptosis that occurs in anchorage-dependent cells upon detachment of those cells from the surrounding extracellular matrix (i.e., the loss of cell anchorage). The anoikis-related proteins βA3/A1 crystallin and E-cadherin are reportedly expressed in retinal ganglion cells. 
  • 3.9K
  • 05 Mar 2021
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