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Topic Review
Effective Atomic Number
Effective atomic number has two different meanings: one that is the effective nuclear charge of an atom, and one that calculates the average atomic number for a compound or mixture of materials. Both are abbreviated Zeff.
  • 4.3K
  • 22 Nov 2022
Topic Review
Infrared Spectroscopy in Biological Studies
Infrared (IR) radiation is electromagnetic radiation with wavenumbers ranges of 12,500–10 cm−1. The IR region in the electromagnetic spectrum can be subdivided into three spectral regions, namely near-IR (NIR, 12,500–4000 cm−1), mid-IR (MIR, 4,000–400 cm−1), and far-IR (FIR, 400–10 cm−1). Accumulating evidence has shown that IR radiation has been widely investigated for biological studies and effects. The interaction between IR radiation and biomolecules enables to study the specific molecular vibrations of the sample constituents. IR spectroscopy, specifically MIR, has been used to investigate large numbers of biological samples such as cells, tissues, organ, and biofluids, providing qualitative and quantitative information that could be used for detection and classification. Notably, FTIR spectroscopy is considered a promising tool to study and analyze biological samples using MIR radiation. 
  • 4.3K
  • 09 Jan 2023
Topic Review
Dry Permanent Magnetic Separator
Dry magnetic separation is a technology that sorts magnetic minerals from gangue using air as the medium instead of water. When raw ore is fed to the magnetic separator, the magnetic particles are subjected to magnetic force due to the nonuniform magnetic field. When the magnetic force exceeds the competitive force (i.e., gravity and fluid drag force), the particles are captured on or attracted towards the surface of the drum and consequently enter the magnetic product. Meanwhile, the gangue or poor intergrowth particles are not subjected to magnetic force and are separated into the non-magnetic product under the action of competitive force. In other words, magnetic minerals and gangue have different trajectories in a magnetic separator, thereby achieving the purpose of separation. Dry magnetic separation has been recently adopted by plants to cope with cost and environmental pressures.
  • 4.3K
  • 24 Oct 2022
Topic Review
Intraretinal Fluid Pattern Characterization
The accumulation of fluids in the retinal layers is one of the main causes of blindness in developed countries. The main strategy for its study and diagnosis is through the use of Optical Coherence Tomography (OCT) images. This allows experts to observe the layers of the retina in a cross-sectional view. Commonly, for the analysis of these accumulations by means of computer diagnostic support systems, precise segmentation strategies are employed.
  • 4.3K
  • 22 Apr 2021
Topic Review
Relative Direction
The most common relative directions are left, right, forward(s), backward(s), up, and down. No absolute direction corresponds to any of the relative directions. This is a consequence of the translational invariance of the laws of physics: nature, loosely speaking, behaves the same no matter what direction one moves. As demonstrated by the Michelson-Morley null result, there is no absolute inertial frame of reference. There are definite relationships between the relative directions, however. Left and right, forward and backward, and up and down are three pairs of complementary directions, each pair orthogonal to both of the others. Relative directions are also known as egocentric coordinates.
  • 4.3K
  • 24 Nov 2022
Topic Review
OX40-OX40L Inhibition for the Treatment of Atopic Dermatitis
OX40 and OX40L are two checkpoint molecules that bind to potentiate pro-inflammatory T-cell responses that are pivotal to atopic dermatitis pathogenesis. Two OX40-OX40L inhibitors, rocatinlimab and amlitelimab, are being developed for the treatment of atopic dermatitis. Rocatinlimab, an anti-OX40 antibody, was evaluated in phase 2b, a randomized, placebo-controlled clinical trial. At week 16, rocatinlimab groups achieved a greater reduction in the EASI percentage change from the baseline (−48.3% to −61.1%) against the placebo (−15.0%; p < 0.001), and clinical response was maintained 20 weeks after the treatment had ceased. Amlitelimab, an anti-OX40L antibody, was studied in a 12-week treatment phase 2a clinical trial, with a significant efficacy response observed within 2 weeks. At week 16, amlitelimab groups reached the EASI mean percentage change from the baseline of −69.9% and −80.1% versus the placebo (−49.4%; p = 0.072 and p = 0.009). Among the responders, 68% of amlitelimab patients were sustained 24 weeks following the last dose. Both treatments were shown to be safe and well tolerated. The evidence points to OX40-OX40L inhibitors as future options for atopic dermatitis treatment with potential disease-modifying effects.
  • 4.3K
  • 17 Feb 2023
Topic Review
Mercedes-Benz GLC-Class
The Mercedes-Benz GLC-Class (X253/C253) is a compact luxury crossover SUV introduced in 2015 for the 2016 model year that replaces the GLK-Class. According to Mercedes-Benz, it is the SUV equivalent to the C-Class. Although officially considered compact, it is considered mid-size in the US market. Under the vehicle naming scheme maintained by Mercedes-Benz, SUVs use the base name "GL", followed by the model's placement in Mercedes-Benz hierarchy. The "G" is for Geländewagen (German for off-road vehicle) and alludes to the long-running G-Class. This is followed by the letter "L" that acts as a linkage with the letter "C" to signify that the vehicle is a SUV equivalent to the C-Class.
  • 4.3K
  • 21 Oct 2022
Topic Review
Major Synthetic Fuels
A concise yet comprehensive overview of major synthetic fuels currently in production worldwide. The fuels are virtually categorised in an intelligible manner with detailed descriptions of their chemical equations, feedstocks, production processes, applications, and global market leaders.
  • 4.3K
  • 27 Mar 2023
Topic Review Peer Reviewed
Domestic Violence against Women and COVID-19
Domestic violence against women is defined as harmful behavior that occurs within a home and it involves aggressive and violent conduct towards women. Since the outbreak of the COVID-19 pandemic, and following the restrictions imposed to combat the pandemic (lockdowns, staying at home, isolation), domestic violence against women has increased worldwide. The current entry presents existing knowledge and discusses issues important for public awareness.
  • 4.3K
  • 14 Apr 2022
Topic Review
Hyperfiltration
Hyperfiltration is an important underlying cause of glomerular dysfunction associated with several systemic and intrinsic glomerular conditions leading to chronic kidney disease (CKD). These include obesity, diabetes, hypertension, focal segmental glomerulosclerosis (FSGS), congenital abnormalities and reduced renal mass (low nephron number). Hyperfiltration-associated biomechanical forces directly impact the cell membrane, generating tensile and fluid flow shear stresses in multiple segments of the nephron.
  • 4.3K
  • 01 Mar 2022
Topic Review
World View
A world view or worldview is the fundamental cognitive orientation of an individual or society encompassing the whole of the individual's or society's knowledge and point of view. A world view can include natural philosophy; fundamental, existential, and normative postulates; or themes, values, emotions, and ethics. The term is a calque of the German word Weltanschauung [ˈvɛltʔanˌʃaʊ.ʊŋ] (listen), composed of Welt ('world') and Anschauung ('view' or 'outlook'). The German word is also used in English. It is a concept fundamental to German philosophy and epistemology and refers to a wide world perception. Additionally, it refers to the framework of ideas and beliefs forming a global description through which an individual, group or culture watches and interprets the world and interacts with it. Worldview remains a confused and confusing concept in English, used very differently by linguists and sociologists. It is for this reason that James W. Underhill suggests five subcategories: world-perceiving, world-conceiving, cultural mindset, personal world, and perspective. Worldviews are often taken to operate at a conscious level, directly accessible to articulation and discussion, as opposed to existing at a deeper, pre-conscious level, such as the idea of "ground" in Gestalt psychology and media analysis. However, core worldview beliefs are often deeply rooted, and so are only rarely reflected on by individuals, and are brought to the surface only in moments of crises of faith.
  • 4.3K
  • 26 Oct 2022
Topic Review
Biomechanical Factors in Track and Field Sprint Start
In athletics sprint events, the block start performance can be fundamental to the outcome of a race. Several biomechanical determinants of sprinters have been identified. In the “Set” position, an anthropometry-driven block setting facilitating the hip extension and a rear leg contribution should be encouraged. At the push-off, a rapid extension of both hips and greater force production seems to be important. After block exiting, shorter flight times and greater propulsive forces are the main features of best sprinters. 
  • 4.3K
  • 13 Apr 2022
Topic Review
Iron Complexation and Flavonoids
Flavonoids are common plant natural products able to suppress ROS-related damage and alleviate oxidative stress. One of key mechanisms, involved in this phenomenon is chelation of transition metal ions. From a physiological perspective, iron is the most significant transition metal, because of its abundance in living organisms and ubiquitous involvement in redox processes. The chemical, pharmaceutical, and biological properties of flavonoids can be significantly affected by their interaction with transition metal ions, mainly iron.
  • 4.3K
  • 26 Jan 2021
Topic Review
Mineral Characterization Using Scanning Electron Microscopy (SEM)
Scanning electron microscopy (SEM) is a powerful tool in the domains of materials science, mining, and geology owing to its enormous potential to provide unique insight into micro and nanoscale worlds. The rapid pace of technological development requires a detailed study of minerals to a further extent to meet the unprecedented material demands of the evolving world. There are more than 5956 species of minerals known today, and the number of new identifications is evolving, with as many as 50 new types identified each year. Quantitative measurements and qualitative analyses of mineral compositions within mining ores and reservoirs have valuable importance with practical applications. Comprehensive and accurate information can be gathered for the identification of rocks and minerals, including structural characteristics and mineral composition, which can provide worthy information about pore structure and reservoir heterogeneity.
  • 4.3K
  • 29 Dec 2023
Topic Review
Shafa'ah
Shafa'ah (Arabic: شفاعه, "intercession"; Turkish: şefaat; Urdu: shafaat‎), in Islam is the act of pleading to God by an intimate friend of God (Muslim saint) for forgiveness. Shafa' a close meaning to Tawassul, which is the act of resorting to intimate friends of God to ask forgiveness. The word Shafa'ah is taken from shaf (شَّفْعُ) which means even as opposed to odd. The interceder, therefore, adds his own recommendation to that of petitioner so that the number of pleaders becomes even. Meaning the weak plea of the petitioner become strong by the prestige of the intercessor. Accordingly, Shafa'ah is a form of prayer to request God by the sake of those who are near to Him in order that as a member of the believing community one could hope for the intercession of the intercessors and hence deliverance from eternal damnation though not necessarily from temporary one. Shafa'ah has lately come to be among the most controversial concepts within Islamic thought. This is because some verses of the Quran negate it, if taken into consideration alone, stating that no intercession would be accepted in the day of resurrection. However, some other verses confirm it declaring that only God has the right to intercede in the next life. Finally, a third kind of verses state that some people have the authority to intercede by permission of God. Wahhabies, taking the first two kinds of these verses as true, believe that there is no intercessor but Allah, and say that whoever believes in intercession of anyone other than God is not a Muslim, rather is a polytheist (heretic). Others believe that while intercession should not be a means of emboldening people to committing sins, it should be considered as a ray of hope which lead sinners to the right path after they have wronged themselves. Belief in the intercession of Muhammad developed after his death by both Sunnis and Shiites, however among the Shiite the idea of mediation was extended to include The Twelve Imams and other intimate friends of God too.
  • 4.3K
  • 21 Nov 2022
Topic Review
Sustainability Performance & Sustainable Banking
In the light of Agenda 2030 awareness of sustainability is steadily growing all over the world. Devastating phenomena like pandemics (Sustainable Development Goal 3 (SDGs—Agenda 2030)), poverty (Sustainable Development Goal 1 (SDGs—Agenda 2030)) as well as climate change (Sustainable Development Goal 13 (SDGs—Agenda 2030)) threaten humanity, calling for more sustainable solutions. Although economic growth (Sustainable Development Goal 8 (SDGs—Agenda 2030)) is one of the principal goals for a sustainable future, little research has been devoted to the interface of corporate social responsibility (CSR) and sustainability and their contribution to the financial sector, in view of sustainable banking. Even fewer are the studies concerning sustainable banking in Greece. This paper attempts a comparative overview of sustainability integration into businesses, focusing on the banking industry. The current theoretical analysis initially provides an extended review of the CSR and sustainability concepts, which is followed by a comprehensive analysis of non-financial disclosures (NFDs) and their business value, providing some evidence from Greece. 
  • 4.3K
  • 15 Jun 2021
Topic Review
A Complete Solution to the Millennium Prize Problems
The seven Millennium Prize Problems, announced by the Clay Mathematics Institute in 2000, represented the highest peaks of mathematical inquiry at the turn of the century. They were considered the deepest and most fundamental questions left unanswered by the mathematics of the past. For decades, progress was made in fragments, with brilliant minds chipping away at the edges of these monolithic challenges. The resolution of these problems was not to be found in the incremental application of existing techniques, but required a paradigm shift in our understanding of logic, number, and form—a new language to describe the universe.
  • 4.3K
  • 11 Aug 2025
Topic Review
Plasma electrolytic oxidation
Plasma electrolytic oxidation (PEO) is a promising method for the surface treatment of metals. The procedure takes place within passivating aqueous electrolytes under alternating current patterns and high process voltages. In so far suitable treatment parameters are chosen, this leads to the formation of protective ceramic coatings which technological properties can be adjusted within wide ranges. The article gives an brief introduction to this topic, concerning a historical overview and a summary of the application fields as well as the layer forming mechanisms and parameter dependencies of this process.
  • 4.3K
  • 21 Jul 2020
Topic Review
Volcanic Eruptions
Volcanic eruptions are considered major (very large) when the Volcanic Explosivity Index (VEI) ≥ 5. The nature of the impacts of a VEI ≥ 5 eruption ranges from the destruction of a city, an entire region, climate disturbances as well as to air travel. Even an eruption with VEI < 5 may also have the potential to modify the environment and landscape particularly in proximal and medial facies, as well as surrounding human societies. The variety of environmental destructions due to volcanic eruption differs from primary (e.g., summit collapse, vegetation burning, death), secondary (e.g., atmospheric cooling, global warming), and tertiary (e.g., flood, famine, disease) effects. It is mostly generated by gas emissions, ashes, lava flow, pyroclastic flow, lahar, debris flow, and landslide which results in local and global impacts.
  • 4.3K
  • 14 Apr 2021
Topic Review
Glucosinolate Biosynthesis
Glucosinolates are amino acid-derived plant-specialized metabolites that are largely found within the members of the family Brassicaceae, which includes vegetables such as broccoli, cabbage, and mustard, as well as the model plant Arabidopsis thaliana (thale cress). The aliphatic glucosinolates are derived from methionine, alanine, leucine, isoleucine, or valine; aromatic glucosinolates are built from phenylalanine or tyrosine; and the indole glucosinolates originate with tryptophan. Each of class of glucosinolate shares a core chemical structure consisting of a β-D-glucosyl residue linked to a (Z)-N-hydroximinosulfate ester through a sulfur and a variable amino acid-derived R group. To date, more than 130 glucosinolate molecules, of which Arabidopsis contains 40 mainly derived from methionine and tryptophan, have been described.
  • 4.3K
  • 11 Oct 2021
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