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Topic Review
Marchywka Effect
The Marchywka effect refers to electrochemical cleaning of diamond using an electric field induced with remote electrodes.
  • 1.1K
  • 25 Oct 2022
Topic Review
Acute Necrotizing Ulcerative Gingivostomatitis
Acute necrotizing ulcerative gingivitis (ANUG) is a common, non-contagious infection of the gums with sudden onset. The main features are painful, bleeding gums, and ulceration of inter-dental papillae (the sections of gum between adjacent teeth). This disease, along with necrotizing (ulcerative) periodontitis (NP or NUP) is classified as a necrotizing periodontal disease, one of the seven general types of gum disease caused by inflammation of the gums (periodontitis). The often severe gum pain that characterizes ANUG distinguishes it from the more common chronic periodontitis which is rarely painful. If ANUG is improperly treated or neglected, it may become chronic and/or recurrent. The causative organisms are mostly anaerobic bacteria, particularly Fusobacteriota and spirochete species. Predisposing factors include poor oral hygiene, smoking, poor nutrition, psychological stress, and a weakened immune system. When the attachments of the teeth to the bone are involved, the term NUP is used. Treatment of ANUG is by removal of dead gum tissue and antibiotics (usually metronidazole) in the acute phase, and improving oral hygiene to prevent recurrence. Although the condition has a rapid onset and is debilitating, it usually resolves quickly and does no serious harm. The informal name trench mouth arose during World War I as many soldiers developed the disease, probably because of the poor conditions and extreme psychological stress.
  • 1.1K
  • 16 Nov 2022
Topic Review
TYLCV Infection of Tomatoes
Tomato cultivation is threatened by environmental stresses (e.g., heat, drought) and by viral infection (mainly viruses belonging to the tomato yellow leaf curl virus family—TYLCVs). Unlike many RNA viruses, TYLCV infection does not induce a hypersensitive response and cell death in tomato plants. One of the major effects caused by TYLCV infection of tomato is a decrease in the activation of stress response proteins and metabolites to avoid an acute deleterious plant response, which may impair virus replication. Instead of severe, sometimes lethal response for most plant cells, TYLCV promotes the development of a protective homeostasis response in plants exposed to prolonged environmental stresses, favoring the survival of the plant. The down-regulation of stress proteins and metabolites coincides with the stabilization of their patterns, particularly in tomatoes resistant to TYLCV. These stable patterns are maintained not only in shoot, but also in roots of virus-infected tomatoes. Whether fruit production of pre-inoculation of R-TYLCV tomato seedlings in field and greenhouses located in hot and dry countries provides a solution, even partial, to global warming, remains to be analyzed on a large scale. This routine, adapted to tomato genotype, soil and climate, may help reduce drastically the amount of water used for irrigation by artificially alternating long periods of drought with short periods of irrigation.
  • 1.1K
  • 29 Nov 2022
Topic Review
Macroeconomic and Uncertainty Shocks’ Effects on Energy Prices
Due to the interconnected nature of the modern world, GDP, monetary and fiscal policy variables, corruption, and uncertainty are critical to energy policy decisions. Energy consumption, GDP growth, and energy prices have a causal link in both directions. 
  • 1.1K
  • 27 Mar 2023
Topic Review
The Dependability of 6G Networks
The sixth-generation (6G) communication networks must be highly dependable due to the foreseen connectivity of critical infrastructures through these networks. Dependability is a compound metric of four well-known concepts—reliability, availability, safety, and security.
  • 1.1K
  • 26 Apr 2023
Topic Review
Anthocyanins as a Potential Natural Antidiabetic
Diabetes mellitus (DM) is a metabolic disease characterized by abnormal blood glucose levels-hyperglycemia, caused by a lack of insulin secretion, impaired insulin action, or a combination of both. The incidence of DM is increasing, resulting in billions of dollars in annual healthcare costs worldwide. Therapeutics aim to control hyperglycemia and reduce blood glucose levels to normal. However, most modern drugs have numerous side effects, some of which cause severe kidney and liver problems. On the other hand, natural compounds rich in anthocyanidins (cyanidin, delphinidin, malvidin, pelargonidin, peonidin, and petunidin) have also been used for the prevention and treatment of DM.
  • 1.1K
  • 16 May 2023
Topic Review
Cysteine Modification in Aurora Kinase A
Aurora kinase A (AURKA), which is a member of serine/threonine kinase family, plays a critical role in regulating mitosis. AURKA has drawn much attention as its dysregulation is critically associated with various cancers, leading to the development of AURKA inhibitors, a new class of anticancer drugs. As the spatiotemporal activity of AURKA critically depends on diverse intra- and inter-molecular factors, including its interaction with various protein cofactors and post-translational modifications, each of these pathways should be exploited for the development of a novel class of AURKA inhibitors other than ATP-competitive inhibitors. 
  • 1.1K
  • 05 Jun 2023
Topic Review
Hydrothermal Carbonization of Agricultural Biogas Production Process
In agricultural biogas plants, besides biogas, the by-product digestate is also produced. Due to its high moisture content and organic origin, it can successfully be applied in the hydrothermal carbonization process to avoid the fate of landfilling. The type of feedstock and the parameters of the hydrothermal conversion (HTC) process, such as temperature, pressure and residence time, affects the physical and chemical characteristics of hydrochar. Therefore, its possible application might be as a biofuel, fertilizer, soil improver, adsorber, or catalyst. 
  • 1.1K
  • 01 Aug 2023
Topic Review
Carbon Dots in Biotechnology and Food Technology
Materials with a “nano” structure are increasingly used in medicine and biotechnology as drug delivery systems, bioimaging agents or biosensors in the monitoring of toxic substances, heavy metals and environmental variations. Furthermore, in the food industry, they have found applications as detectors of food adulteration, microbial contamination and even in packaging for monitoring product freshness. Carbon dots (CDs) as materials with broad as well as unprecedented possibilities could revolutionize the economy, if only their synthesis was based on low-cost natural sources. 
  • 1.1K
  • 13 Oct 2023
Topic Review
Bioceramic Materials Used in Regenerative Dentistry
To improve the oral and dental health of the population, regenerative dentistry is a very promising approach that aims both to prevent oral–dental deterioration and to restore the anatomy and functionality of diseased teeth. To this end, it draws on new advances in procedures based on cell biology and new biomaterials. Synthetic biomimetic materials, and particularly bioceramics are undoubtedly fundamental elements in the development of these advanced dental therapies, as the calcium phosphate type formulations are the natural bioceramic components of dental and bone tissues. To this must be added the breakthrough achieved with the new silica-based bioactive ceramic compositions, capable of stimulating biological mineralization processes.
  • 1.1K
  • 24 Oct 2023
Topic Review
Hydatid Cyst Chemotherapy by Nanotechnology
Hydatid cysts have been widely recognized for decades as a common medical problem that affects millions of people. A revolution in medical treatment may be on the prospect of nanotechnology enhancing chemotherapy against hydatid cysts.
  • 1.1K
  • 17 Nov 2023
Topic Review
Anti-DFS70 in Systemic Autoimmune Rheumatic Diseases
The diagnosis of systemic autoimmune rheumatic disease (SARD) or its exclusion is carried out taking into account the results of immunological studies, primarily antinuclear antibodies (ANA) and specific autoantibodies. Often, during ANA analysis via indirect immunofluorescence reaction on cellular and tissue substrates, a dense fine speckled 70 (DFS70) fluorescence pattern is observed.
  • 1.1K
  • 30 Jan 2024
Topic Review
FG Syndrome
FG syndrome is a genetic condition that affects many parts of the body and occurs almost exclusively in males. "FG" represents the surname initials of the first family diagnosed with the disorder.
  • 1.1K
  • 25 Dec 2020
Topic Review
Rawlsian Cost-Benefit Analysis
The use of a Rawlsian perspective in cost-benefit analysis is proposed. For the purposes of the cost-benefit analysis, this perspective is at least as adequate as the traditional perspective, of a utilitarian nature.
  • 1.1K
  • 17 Nov 2021
Topic Review
Extract from Beetle Ulomoides dermestoides
A biologically active extract from the darkling beetle Ulomoides dermestoides was obtained using the electro-pulse plasma dynamic extraction method. The beetle water extract contained a complex of antioxidant substances such as antioxidant enzymes and nonprotein antioxidants, as well as a complex of heat shock antistress proteins. This determines the rather high antioxidant activity of the aqueous extract of the beetle, i.e., 1 mg of dry matter/mL of the extract has an equivalent antioxidant activity to 0.2 mM Trolox (a water-soluble analog of vitamin E). It was shown that the beetle extract can lead to a 25–30% increase in the average lifespan of nematode Caenorhabditiselegans, under normal conditions, and a 12–17% increase under conditions of oxidative stress (with paraquat), and significantly inhibits the fructosylation reaction of serum albumin. Therefore, the beetle aqueous extract shows promise as a biologically active complex exhibiting antioxidant activity.
  • 1.1K
  • 08 Oct 2021
Topic Review
Anglophone Problem (Cameroon)
The Anglophone Problem, as it is commonly referred to in Cameroon, is a socio-political issue rooted in Cameroon's colonial legacies from the Germans, British, and the French. The issue classically and principally opposes many Cameroonians from the Northwest and Southwest regions, many of whom consider themselves anglophones, to the Cameroon government. This is based on the fact that these two regions (formally British Southern Cameroons) were controlled by Britain as a mandated and trust territory of the League of Nations and the United Nations respectively."
  • 1.1K
  • 15 Nov 2022
Topic Review
Ternary Al–Ni–Er System
Al–Ni–Er is an essential system in heat-resistant Al alloys. The aluminum-rich corner of this system, which has the most practical application significance. The phase equilibria of the Al–Ni–Er system are investigated via experiments and thermodynamic modeling. The isothermal sections of the Al-rich corner of this ternary system at 600 and 700 °C were determined through equilibrated alloys combined with scanning electron microscopy (SEM), electron probe microanalysis (EPMA) and X-ray diffractometry (XRD).
  • 1.1K
  • 03 Nov 2023
Topic Review
Biomedical Applications of Antiviral Nanohybrids
The COVID-19 pandemic has driven a global research to uncover novel, effective therapeutical and diagnosis approaches. In addition, control of spread of infection has been targeted through development of preventive tools and measures. In this regard, nanomaterials, particularly, those combining two or even several constituting materials possessing dissimilar physicochemical (or even biological) properties, i.e., nanohybrid materials play a significant role. Nanoparticulate nanohybrids have gained a widespread reputation for prevention of viral crises, thanks to their promising antimicrobial properties as well as their potential to act as a carrier for vaccines. On the other hand, they can perform well as a photo-driven killer for viruses when they release reactive oxygen species (ROS) or photothermally damage the virus membrane. The nanofibers can also play a crucial protective role when integrated into face masks and personal protective equipment, particularly as hybridized with antiviral nanoparticles.
  • 1.1K
  • 16 Sep 2021
Topic Review
Denoising Technique for CT Images
Denoising computed tomography (CT) medical images is crucial in preserving information and restoring images contaminated with noise. Standard filters have extensively been used for noise removal and fine details’ preservation. During the transmission of medical images, noise degrades the visibility of anatomical structures and subtle abnormalities, making it difficult for radiologists to accurately diagnose and interpret medical conditions. 
  • 1.1K
  • 07 Apr 2024
Topic Review
The Sustainability Concept Focusing on Energy
The concept of sustainability, with a focus on energy, has emerged as a central tenet in addressing the mounting global challenges of environmental degradation and resource depletion. Indicators of sustainability focusing on energy are crucial tools used to assess and monitor progress toward achieving a more sustainable energy system. These indicators provide valuable insights into the environmental, social, and economic dimensions of energy practices and their long-term impacts. By analyzing and understanding these indicators, policymakers, businesses, and communities can make informed decisions, formulate effective policies, and steer their efforts toward a more sustainable energy future. These indicators serve as navigational guides, steering the world toward energy practices that support both present needs and the well-being of future generations. 
  • 1.1K
  • 06 Oct 2023
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