Your browser does not fully support modern features. Please upgrade for a smoother experience.
Subject:
All Disciplines Arts & Humanities Biology & Life Sciences Business & Economics Chemistry & Materials Science Computer Science & Mathematics Engineering Environmental & Earth Sciences Medicine & Pharmacology Physical Sciences Public Health & Healthcare Social Sciences
Sort by:
Most Viewed Latest Alphabetical (A-Z) Alphabetical (Z-A)
Filter:
All Topic Review Biography Peer Reviewed Entry Video Entry
Topic Review
MNPs@QDs
The presence of food contaminants can cause foodborne illnesses, posing a severe threat to human health. Therefore, a rapid, sensitive, and convenient method for monitoring food contaminants is eagerly needed. The complex matrix interferences of food samples and poor performance of existing sensing probes bring significant challenges to improving detection performances. Nanocomposites with multifunctional features provide a solution to these problems. The combination of the superior characteristics of magnetic nanoparticles (MNPs) and quantum dots (QDs) to fabricate magnetic fluorescent quantum dots (MNPs@QDs) nanocomposites are regarded as an ideal multifunctional probe for food contaminants analysis.
  • 1.3K
  • 22 Apr 2022
Topic Review
Heat Stress
Heat stress (HS) is a prevalent negative factor affecting plant growth and development, as it is predominant worldwide and threatens agriculture on a large scale. PHYTOCHROMES (PHYs) are photoreceptors that control plant growth and development, and the stress signaling response partially interferes with their activity. 
  • 1.3K
  • 20 Apr 2022
Topic Review
Central Bank Digital Currency
Due to the growth of the internet and communication technologies, electronic financial systems are becoming popular. Physical cash is losing its preeminence, and digital numbers on computers represent money. However, electronic financial systems, mostly operated by private entities, have defects to be compensated for, such as high charges for using the system, security issues, and the problem of exclusion. As a solution, many countries around the world are considering central bank digital currency. For central bank digital currency to be utilized as a national legal tender, it must be universal and accessible regardless of time and place, similar to physical cash. Therefore, offline payment functions that extend the accessibility of central bank digital currency are becoming attractive.
  • 1.3K
  • 26 May 2022
Topic Review
Pancreatic Cancer and Microenvironments: Implications of Anesthesia
Pancreatic malignancy is a lethal neoplasm, as well as one of the leading causes of cancer-associated mortality, having a 5-year overall survival rate of less than 10%. The average life expectancy of patients with advanced pancreatic cancer does not exceed six months. Although surgical excision is a favorable modality for long-term survival of pancreatic neoplasm, metastasis is initially identified in nearly 80% of the patients by the time of diagnosis, making the development of therapeutic policy for pancreatic cancer extremely daunting. Emerging evidence shows that pancreatic neoplastic cells interact intimately with a complicated microenvironment that can foster drug resistance, metastasis, or relapse in pancreatic cancer. As a result, the necessity of gaining further insight should be focused on the pancreatic microenvironment contributing to cancer progression. Numerous evidence reveals that perioperative factors, including surgical manipulation and anesthetics (e.g., propofol, volatile anesthetics, local anesthetics, epidural anesthesia/analgesia, midazolam), analgesics (e.g., opioids, non-steroidal anti-inflammatory drugs, tramadol), and anesthetic adjuvants (such as ketamine and dexmedetomidine), might alter the tumor microenvironment and cancer progression by affecting perioperative inflammatory or immune responses during cancer surgery. 
  • 1.3K
  • 09 Jun 2022
Topic Review
Artificial Scaffolds in Cardiac Tissue Engineering
Scaffolds for cardiac tissue engineering are tridimensional porous structures that imitate the extracellular heart matrix, with the ability to promote cell adhesion, migration, differentiation, and proliferation. In the heart, there is an important requirement to provide scaffold cellular attachment, but scaffolds also need to permit mechanical contractility and electrical conductivity. For researchers working in cardiac tissue engineering, there is an important need to choose an adequate artificial scaffold biofabrication technique, as well as the ideal biocompatible biodegradable biomaterial for scaffold construction. Finally, there are many suitable options for researchers to obtain scaffolds that promote cell–electrical interactions and tissue repair, reaching the goal of cardiac tissue engineering. 
  • 1.3K
  • 03 Aug 2022
Topic Review
Antiviral Drugs Employing Toll-like Receptors in SARS-CoV-2
The innate immune system facilitates defense mechanisms against pathogen invasion and cell damage. Toll-like receptors (TLRs) assist in the activation of the innate immune system by binding to pathogenic ligands. This leads to the generation of intracellular signaling cascades including the biosynthesis of molecular mediators. TLRs on cell membranes are adept at recognizing viral components. Viruses can modulate the innate immune response with the help of proteins and RNAs that downregulate or upregulate the expression of various TLRs. In the case of COVID-19, molecular modulators such as type 1 interferons interfere with signaling pathways in the host cells, leading to an inflammatory response. Coronaviruses are responsible for an enhanced immune signature of inflammatory chemokines and cytokines. TLRs have been employed as therapeutic agents in viral infections as numerous antiviral Food and Drug Administration-approved drugs are TLR agonists. 
  • 1.3K
  • 30 Sep 2022
Topic Review
Cisplatin Resistance
Cisplatin (CDDP) is the drug of choice against different types of cancer. However, tumor cells can acquire resistance to the damage caused by cisplatin, generating genetic and epigenetic changes that lead to the generation of resistance and the activation of intrinsic resistance mechanisms in cancer cells. 
  • 1.3K
  • 18 Oct 2022
Topic Review
4Th Dimension
4D (4th Dimension, or Silver Surfer, as it was known during early development) is a relational database management system and IDE developed by Laurent Ribardière. 4D was created in 1984 and had a slightly delayed public release for Macintosh in 1987 with its own programming language. The 4D product line has since expanded to an SQL back-end, integrated compiler, integration of PHP, and several productivity plug-ins and interfaces. Some of the plug-ins created by 4D include 4D Write (a word processor), 4D View (somewhat like a spreadsheet, but with extra functionality) and 4D Internet Commands (which allowed for the addition of Internet-related functionality to a database). There are also over 100 third-party plugins, free and commercial. 4D can also be used as a web server, to run compiled database applications. Today, 4D is published by the France company 4D SAS and has a sales, distribution and support presence in most major markets, with the United States, the United Kingdom, and France being the primary markets. The product is localized in more than a dozen languages.
  • 1.3K
  • 02 Nov 2022
Topic Review
Psychic Numbing
Psychic numbing is a tendency for individuals or societies to withdraw attention from past experiences that were traumatic, or from future threats that are perceived to have massive consequences but low probability. Psychic numbing can be a response to threats as diverse as financial and economic collapse, the risk of nuclear weapon detonations, pandemics, and global warming. It is also important to consider the neuroscience behind the phenomenon, which gives validation to the observable human behavior. The term has evolved to include both societies as well as individuals, so psychic numbing can be viewed from either a collectivist or an individualist standpoint. Individualist psychic numbing is found in victims of rape and people who suffer from post-traumatic stress disorder.
  • 1.3K
  • 03 Nov 2022
Topic Review
Sanitation Workers in African cities
Sanitation workers provide an essential public service that is key to achieving the Sustainable Development Goals (SDG), but often costs them their dignity and health. Many governments in low- and middle-income countries fail to support their sanitation workforce. This is due, in part, to a lack of knowledge about sanitation workers’ needs and the challenges they face. 
  • 1.3K
  • 06 Dec 2022
Topic Review
Influenzavirus C
Influenza virus C is a genus in the virus family Orthomyxoviridae, which includes the viruses that cause influenza. The species in this genus is called Influenza C virus. Influenza C viruses are known to infect humans and pigs. Flu due to the Type C species is rare compared to Types A or B, but can be severe and can cause local epidemics. Type C has 7 RNA segments and encodes 9 proteins, while Types A and B have 8 RNA segments and encode at least 10 proteins.
  • 1.3K
  • 01 Dec 2022
Topic Review
Efavirenz
Efavirenz (Sustiva®) is a first-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) used to treat human immunodeficiency virus (HIV) type 1 infection or to prevent the spread of HIV. In 1998, the FDA authorized efavirenz for the treatment of HIV-1 infection. Patients formerly required three 200 mg efavirenz capsules daily, which was rapidly updated to a 600 mg tablet that only required one tablet per day.
  • 1.3K
  • 11 Jan 2023
Topic Review
The Benefits of Using Phosphate-Solubilizing Biofertilizers
Chemical phosphatic fertilizers are mainly produced from phosphate rocks, a natural reserve that is depleting rapidly. These chemical phosphatic fertilizers are polluting the environment at an alarming rate as a result of injudicious application to farmlands. On the other hand, phosphate-solubilizing biofertilizers (PSBs) are often considered better alternatives to industrial phosphatic fertilizers in many ways. PSBs are microorganisms capable of solubilizing insoluble forms of phosphate into soluble plant-usable forms. The impacts of phosphatic fertilizers are discussed and making the case for why we should shift to PSBs instead. Phosphatic fertilizers have numerous impacts on the environment (water bodies, land resources, and air), and micro- and macro-organisms, including humans. Chemical fertilizers also tend to be more expensive, especially for farmers in developing countries. On the contrary, PSBs tend to be safer and way more beneficial than their chemical counterparts in that they are environmentally friendly and cheaper options of availing plant-usable phosphorus. PSBs are also involved in other beneficial roles such as the production of phytohormones and secretion of anti-phytopathogenic metabolites. The phytohormones enhance plant growth and the metabolites render crops immunity against phytopathogens. Hence, it is vital to replace chemical phosphatic fertilizers with PSB inoculants both to prevent the irreversible impacts of chemical fertilizers and to take advantage of the numerous benefits of PSBs. 
  • 1.3K
  • 13 Feb 2023
Topic Review
Electrochemical Methods for Liquid Biopsy
The screening and early diagnosis of diseases are crucial for a patient’s treatment to be successful and to improve their survival rate, especially for cancer. The development of non-invasive analytical methods able to detect the biomarkers of pathologies is a critical point to define a successful treatment and a good outcome. A biopsy is a technique in which tissue samples are taken from the body and examined under a microscope to see if cancer (though the concept is applicable to many other diseases) or abnormal cells are present. Electrochemical methods, such as electrochemical impedance spectroscopy (EIS), differential pulse voltammetry (DPV), and cyclic voltammetry (CV), play a crucial role in both the development of biosensors and the evaluation of their performance. These methods are highly valuable approaches in the field of liquid biopsy.
  • 1.3K
  • 18 Oct 2023
Topic Review
Preceramic Polymers for Additive Manufacturing of Silicate Ceramics
The utilization of preceramic polymers (PCPs) to produce both oxide and non-oxide ceramics has caught significant interest, owing to their exceptional characteristics. Diverse types of polymer-derived ceramics (PDCs) synthesized by using various PCPs have demonstrated remarkable characteristics such as exceptional thermal stability, resistance to corrosion and oxidation at elevated temperatures, biocompatibility, and notable dielectric properties, among others. The application of additive manufacturing techniques to produce PDCs opens up new opportunities for manufacturing complex and unconventional ceramic structures with complex designs that might be challenging or impossible to achieve using traditional manufacturing methods. This is particularly advantageous in industries like aerospace, automotive, and electronics. 
  • 1.3K
  • 19 Dec 2023
Topic Review
Myoclonic Epilepsy Myopathy Sensory Ataxia
Myoclonic epilepsy myopathy sensory ataxia, commonly called MEMSA, is part of a group of conditions called the POLG-related disorders.
  • 1.3K
  • 23 Dec 2020
Topic Review
Pharmaceutical and Microplastic Pollution in Water
Pharmaceuticals (PhACs) and microplastics (MPs) are emerging pollutants that pose serious environmental risks. PhACs have been found in low concentrations in a variety of environmental samples, including sewage treatment plant effluents, surface water, seawater, and groundwater, in a number of countries.
  • 1.3K
  • 27 Oct 2022
Topic Review
Single-Particle Analysis of Atmospheric Aerosols
Atmospheric aerosols, produced as a consequence of different anthropogenic and natural processes, impart significant control over the global energy budget, climate, and human-environmental health. Their size varies across the nano-micrometer scale. Based on their origin, they may be classified into primary or secondary aerosols. Biomass burning, incomplete combustion of fossil fuels, volcanic eruptions, and traffic-related and wind-driven suspensions contribute to primary aerosol emissions. In contrast, gas-to-particle conversion within the atmosphere leads to secondary particle production. The study of atmospheric aerosols is vital to the field of atmospheric research. The dynamic nature (highly variable concentration composition and size with space and time) of aerosols makes them difficult to investigate. Today, aerosol research involves the application of various spectrometric and spectroscopic techniques. The single-particle analysis of aerosol is yet a challenge. The merits and demerits of various offline and online techniques used for aerosol research are discussed in a nutshell. Mass spectrometric techniques fail in distinguishing certain species.
  • 1.3K
  • 10 Nov 2022
Topic Review
Plant Growth Inhibition Induced by Heavy Metals
Heavy metals are included as one of the main abiotic stresses which reduces plant development and productivity all over the world. 
  • 1.3K
  • 01 Feb 2023
Topic Review
Post-COVID Syndrome
Post-COVID syndrome is increasingly recognized as a new clinical entity in the context of SARS-CoV-2 infection.
  • 1.3K
  • 23 Jun 2021
  • Page
  • of
  • 2728
Featured Entry Collections
>>

Featured Reprints

>>
Encyclopedia of Digital Society, Industry 5.0 and Smart City
Encyclopedia of Engineering
Encyclopedia of Social Sciences
Encyclopedia of Medieval Royal Iconography
Academic Video Service
Feedback