Your browser does not fully support modern features. Please upgrade for a smoother experience.
Subject:
All Disciplines Arts & Humanities Biology & Life Sciences Business & Economics Chemistry & Materials Science Computer Science & Mathematics Engineering Environmental & Earth Sciences Medicine & Pharmacology Physical Sciences Public Health & Healthcare Social Sciences
Sort by:
Most Viewed Latest Alphabetical (A-Z) Alphabetical (Z-A)
Filter:
All Topic Review Biography Peer Reviewed Entry Video Entry
Topic Review
Music Transcription
Music transcription is the process of transforming recorded sound of musical performances into symbolic representations such as sheet music or MIDI files. At the most fundamental level, frame-level transcription involves analyzing very short frames of audio and identifying basic sound characteristics of music such as pitch and timbre. In the next step, note-level transcription takes the information gathered from frame-level analysis and assembles it into individual musical notes. This level of transcription can identify the pitch, duration, and timing of each note in the piece of audio. The stream-level transcription looks beyond individual notes to capture the larger musical phrases. This involves recognizing patterns in the sequence of notes, identifying chord progressions, and determining the overall structure of the music like verses and choruses in a song. The highest level of transcription involves creating a formal written representation of the music notation. This includes not only the individual notes and their timing but also various musical symbols such as dynamics, articulations, time signatures, key signatures, and more. 
  • 1.4K
  • 08 Nov 2023
Topic Review
Camera-LiDAR-Based 3D Object Detection Methods
Three-dimensional (3D) object detection is a topic that has gained interest within the scientific community dedicated to vehicle automation. Based on LiDAR and stereo cameras, and considering only deep learning-based approaches, 3D object detection methods are classified according to the type of input data: camera-based, LiDAR-based, and fusion-based 3D object detection.
  • 1.4K
  • 15 Mar 2024
Topic Review
Cutaneous Flavonoid Delivery System
Flavonoids are one of the vital classes of natural polyphenolic compounds abundantly found in plants. Due to their wide range of therapeutic properties, which include antioxidant, anti-inflammatory, photoprotective, and depigmentation effects, flavonoids have been demonstrated to be promising agents in the treatment of several skin disorders. However, their lipophilic nature and poor water solubility invariably lead to limited oral bioavailability. In addition, they are rapidly degraded and metabolized in the human body, hindering their potential contribution to the prevention and treatment of many disorders. Thus, to overcome these challenges, several cutaneous delivery systems have been extensively studied. Topical drug delivery besides offering an alternative administration route also ensures a sustained release of the active compound at the desired site of action. Incorporation into lipid or polymer-based nanoparticles appears to be a highly effective approach for cutaneous delivery of flavonoids with good encapsulation potential and reduced toxicity.
  • 1.4K
  • 22 Apr 2022
Topic Review Video
Mild-to-Moderate Traumatic Brain Injury
Traumatic Brain Injury (TBI) is a major global public health problem. Neurological damage from TBI may be mild, moderate, or severe and occurs both immediately at the time of impact (primary injury) and continues to evolve afterwards (secondary injury). In mild (m)TBI, common symptoms are headaches, dizziness, and fatigue. Visual impairment is especially prevalent. Insomnia, attentional deficits and memory problems often occur. While symptoms resolve spontaneously in many, residual effects may linger for months or years in some mTBI patients. Optimally, the goal of any intervention is a return to baseline uninjured functioning with restoration of the ability to conduct daily activities.  
  • 1.4K
  • 16 Jun 2022
Topic Review
Battery Energy Storage Systems
The battery energy storage system can be applied to store the energy produced by renewable energy sources (RESs) and then utilized regularly and within limits as necessary to lessen the impact of the intermittent nature of renewable energy sources.
  • 1.4K
  • 12 Sep 2023
Topic Review
Hydrogel Adhesives for Gastrointestinal Perforation
The gastrointestinal tract (GI) contains all the major organs of the digestive system, including the esophagus, stomach, small intestine (duodenum, jejunum, and ileum), and large intestine (cecum, colon, and rectum). It is essential for the transportation, digestion, and absorption of food. Hydrogel adhesives are emerging as an attractive alternative to sutures and staples for treating internal tissue wounds including wounds present in the GI tract. Hydrogels are three-dimensional, hydrophilic, crosslinked polymer networks that absorb and retain large amounts of water to maintain a gel-like swollen state.
  • 1.4K
  • 13 Apr 2023
Topic Review
Veterinary Antiparasitic to Human Anticancer
Cancer is an extensive disease and the most common cause of morbidity and mortality worldwide. It is characterized by a deregulation of the cell cycle, which primarily results in a progressive loss of control of cellular growth and differentiation. The repurposing of veterinary antiparasitic drugs for the treatment of cancer is gaining traction, as supported by existing literature. A prominent example is the proposal to implement the use of veterinary antiparasitics such as benzimidazole carbamates and halogenated salicylanilides as novel anticancer drugs. These agents have revealed pronounced anti-tumor activities and gained special attention for “double repositioning”, as they are repurposed for different species and diseases simultaneously, acting via different mechanisms depending on their target. As anticancer agents, these compounds employ several mechanisms, including the inhibition of oncogenic signal transduction pathways of mitochondrial respiration and the inhibition of cellular stress responses.
  • 1.4K
  • 29 Apr 2022
Topic Review
Vulvovaginal Candidosis
Vulvovaginal candidosis (VVC) is a frequently occurring infection of the lower female genital tract, mostly affecting immuno-competent women at childbearing age. Candida albicans is the most prevalent pathogenic yeast—apart from other non-albicans species—related to this fungal infection. Different virulence factors of C. albicans have been identified, which increase the risk of developing VVC. To initiate treatment and positively influence the disease course, fast and reliable diagnosis is crucial. In this narrative review, we cover the existing state of understanding of the epidemiology, pathogenesis and diagnosis of VVC. However, treatment recommendations should follow current guidelines.
  • 1.4K
  • 20 Nov 2020
Topic Review
Second-Hits in Hereditary Hemorrhagic Telangiectasia
Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant genetic disorder that presents with telangiectases in skin and mucosae, and arteriovenous malformations (AVMs) in internal organs such as lungs, liver, and brain. Mutations in ENG (endoglin), ACVRL1 (ALK1), and MADH4 (Smad4) genes account for over 95% of HHT. Localized telangiectases and AVMs are present in different organs, with frequencies which differ among affected individuals. By itself, HHT gene heterozygosity does not account for the focal nature and varying presentation of the vascular lesions leading to the hypothesis of a “second-hit” that triggers the lesions. Accumulating research has identified a variety of triggers that may synergize with HHT gene heterozygosity to generate the vascular lesions. Among the postulated second-hits are: mechanical trauma, light, inflammation, vascular injury, angiogenic stimuli, shear stress, modifier genes, and somatic mutations in the wildtype HHT gene allele.
  • 1.4K
  • 08 Mar 2021
Topic Review
Health Benefits of Seaweeds Consumption
Recent studies demonstrate the high nutritional value of seaweeds and the powerful properties that seaweeds’ bioactive compounds provide. Species of class Phaeophyceae, phylum Rhodophyta and Chlorophyta possess unique compounds with several properties that are potential allies of our health, which make them valuable compounds to be involved in biotechnological applications.
  • 1.4K
  • 23 Jun 2021
Topic Review
Phytochemicals of the Genus Maytenus
The genus Maytenus is a member of the Celastraceae family, of which several species have long been used in traditional medicine. Between 1976 and 2021, nearly 270 new compounds have been isolated and elucidated from the genus Maytenus. Among these, maytansine and its homologues are extremely rare in nature. Owing to its unique skeleton and remarkable bioactivities, maytansine has attracted many synthetic endeavors in order to construct its core structure.
  • 1.4K
  • 09 Aug 2021
Topic Review
Engineering Drug Delivery Systems
Engineering drug delivery systems (DDS) aim to release bioactive cargo to a specific site within the human body safely and efficiently. Hydrogels have been used as delivery matrices in different studies due to their biocompatibility, biodegradability, and versatility in biomedical purposes. Microparticles have also been used as drug delivery systems for similar reasons. The combination of microparticles and hydrogels in a composite system has been the topic of many research works. These composite systems can be injected in loco as DDS. The hydrogel will serve as a barrier to protect the particles and retard the release of any bioactive cargo within the particles. Additionally, these systems allow different release profiles, where different loads can be released sequentially, thus allowing a synergistic treatment. The reported advantages from several studies of these systems can be of great use in biomedicine for the development of more effective DDS.
  • 1.4K
  • 04 Oct 2021
Topic Review
Topological and Dissipative Solitons in Liquid Crystals
Solitons are self-sustained localized packets of waves in nonlinear media that propagate without changing shape. They are found everywhere in our daily life from nerve pluses in our bodies to eyes of storms in the atmosphere and even density waves in galaxies. Solitons in liquid crystals have received increasing attention due to their importance in fundamental physical science and potential applications in various fields. 
  • 1.4K
  • 21 Jan 2022
Topic Review
Differential Inhibitors of Aldose Reductase
Aldose reductase, classified within the aldo-keto reductase family as AKR1B1, is an NADPH dependent enzyme that catalyzes the reduction of hydrophilic as well as hydrophobic aldehydes. AKR1B1 is the first enzyme of the so-called polyol pathway that allows the conversion of glucose into sorbitol, which in turn is oxidized to fructose by sorbitol dehydrogenase. The activation of the polyol pathway in hyperglycemic conditions is generally accepted as the event that is responsible for a series of long-term complications of diabetes such as retinopathy, cataract, nephropathy and neuropathy. The role of AKR1B1 in the onset of diabetic complications has made this enzyme the target for the development of molecules capable of inhibiting its activity.
  • 1.4K
  • 11 Apr 2022
Topic Review
Driving Behavior of Educated Youth in Bangladesh
Proper traffic safety is defined as systems and techniques used to safeguard road users against dying or being severely injured. Educated and internet-using Bangladeshi drivers took part in a questionnaire about their emotional stability on an online platform with more than 100 questions comprising two parts. While one of the part outlines the physiological, cultural, and socioeconomic factors and driver education, in another part, an 18-point Driver’s Behavior Questionnaire was introduced to the responders. About 40% of the surveyed drivers in the poll were inexperienced. However, 49% of people prefer to ride two-wheelers. Moreover, 70% of surveyed drivers hold valid driver’s licenses. At the same time, 35.2% of those were college graduates. Even 34.8% of accidents were caused by excessive speed and non-aggressive driving. In addition, age and degree of education were significant indicators of distracted driving violations.
  • 1.4K
  • 07 May 2022
Topic Review
Fine Regulation during Wound Healing by Mast Cells
Mast cells (MCs) are bone marrow-derived cells capable of secreting many active molecules, ranging from the mediators stored in specific granules, some of which have been known about for several decades (histamine, heparin), to small molecules produced immediately upon stimulation (membrane lipid derivatives, nitric oxide), to a host of constitutively secreted, multifunctional cytokines. With the aid of a wide array of mediators, the activated MCs control the key events of inflammation and therefore participate in the regulation of local immune response. On the basis of the structure, origin, principal subtypes, localization and function of these cells, their involvement in injury repair is therefore to be considered in acute and chronic conditions, respectively.
  • 1.4K
  • 30 Jul 2022
Topic Review
Inventory (Library)
Inventories are the one method that libraries use to determine whether some items in their collection are in need of preservation or conservation activities. A modern inventory might involve examining item by item with a barcode scanner and a laptop, with the objective of adjusting bibliographic and item records in theirs and OCLC's WorldCat databases. Using a laptop and handheld bar code reader will “reduce human error and inconsistencies, while helping to maintain staff concentration and enthusiasm for the project”. Print materials in the digital age, though dramatically decreased in size compared to e-print materials, are still valuable components of a library's collection. Increasing print material's accessibility, and reducing user frustration, make the inventory process an effective tool in improving library service quality. “When library users are unable to find materials in the expected locations, they lose confidence in the library catalog as well as in the library itself”. Missing or mislabeled books have a direct impact on the quality of library services. Maintaining the stacks through inventories and shelf reading can mitigate staff time lost searching for missing or mislabeled items. Libraries have thousands of books; large academic libraries may have millions of books;. Doing an annual (or less frequent) physical inventory with the laying on of hands on each individual item may not be practical for several reasons. It may not be financially feasible, employees required may not have extra time to devote to such an inventory, and there are no financial rewards for the Library for completing an inventory. Problems that are discovered (books in need of repurchase, rebinding, repair, or digitization) may require solutions that are expensive and labor-intensive. Because of these restraints, inventories may not take place for decades, if ever, at large academic institutions. By contrast, complete inventories are often a regular part of the school library media specialist's job at K-12 institutions, where inventory may be a legal requirement that shows that the libraries are accountable for the money they have spent throughout the year. Checking for lost books and materials can be similarly compared to auditing. However, there are alternative options to performing a complete inventory, such as performing a selective inventory. Selective inventory can be performed by circumstance or by data prediction. Physical space is a premium in libraries. Inventorying mini collections before relocating them to their new location presents the library with an opportunity to perform a selective inventory project. An alternative to opportunistic selective inventory projects is Kohl's (1982) assertion that circulation statistics, book search statistics, and ILL statistics can be useful tools in identifying areas as possible selective inventory areas. He writes, “areas in need of an inventory can be identified through the use of predictive data”. Once the objectives for accuracy and methods of measuring have been established “the criteria need to be quantified. An overall measure of the inventory accuracy should be maintained as a management key performance indicator”.
  • 1.4K
  • 01 Nov 2022
Topic Review
Avian Influenza
Avian influenza, known informally as avian flu or bird flu, is a variety of influenza caused by viruses adapted to birds.[note 1] The type with the greatest risk is highly pathogenic avian influenza (HPAI). Bird flu is similar to swine flu, dog flu, horse flu and human flu as an illness caused by strains of influenza viruses that have adapted to a specific host. Out of the three types of influenza viruses (A, B, and C), influenza A virus is a zoonotic infection with a natural reservoir almost entirely in birds. Avian influenza, for most purposes, refers to the influenza A virus. Though influenza A is adapted to birds, it can also stably adapt and sustain person-to-person transmission. Recent influenza research into the genes of the Spanish flu virus shows it to have genes adapted from both human and avian strains. Pigs can also be infected with human, avian, and swine influenza viruses, allowing for mixtures of genes (reassortment) to create a new virus, which can cause an antigenic shift to a new influenza A virus subtype which most people have little to no immune protection against. Avian influenza strains are divided into two types based on their pathogenicity: high pathogenicity (HP) or low pathogenicity (LP). The most well-known HPAI strain, H5N1, was first isolated from a farmed goose in Guangdong Province, China in 1996, and also has low pathogenic strains found in North America. Companion birds in captivity are unlikely to contract the virus and there has been no report of a companion bird with avian influenza since 2003. Pigeons can contract avian strains, but rarely become ill and are incapable of transmitting the virus efficiently to humans or other animals. Between early 2013 and early 2017, 916 lab-confirmed human cases of H7N9 were reported to the World Health Organization (WHO). On 9 January 2017, the National Health and Family Planning Commission of China reported to WHO 106 cases of H7N9 which occurred from late November through late December, including 35 deaths, 2 potential cases of human-to-human transmission, and 80 of these 106 persons stating that they have visited live poultry markets. The cases are reported from Jiangsu (52), Zhejiang (21), Anhui (14), Guangdong (14), Shanghai (2), Fujian (2) and Hunan (1). Similar sudden increases in the number of human cases of H7N9 have occurred in previous years during December and January.
  • 1.4K
  • 11 Nov 2022
Topic Review
Processing Technologies for Thin Kesterite CZTS Absorber Films
Solar cells based on Cu(In, Ga)(S, Se)2 (CIGS) and CdTe thin-film solar cells have already reached the commercial stage, having an efficiency of 23.4% for CIGS and 21.0% for CdTe. However, their marketability has stagnated. A promising solution for a non-toxic and commercially attractive absorber for photovoltaic applications is offered by the family of kesterite semiconductor materials such as copper–zinc–tin–sulfide (with the chemical formula Cu2ZnSnS4) (CZTS) and copper–zinc–tin–selenide (with the chemical formula Cu2ZnSnSe4)(CZTSe) and their alloy family copper–zinc–tin–sulfo–selenide (Cu2ZnSn(Sx,Se1−x)4 (CZTSSe), where 0 ≤ x ≤ 1).
  • 1.4K
  • 02 Dec 2022
Topic Review
Dietary Assessment Tools for Preschool-Aged Children
Preschool-aged children in the U.S. have suboptimal diets. Interventions to improve child nutrition focus on parents and their role in shaping social and physical home environments, which influence children’s eating behaviors. Dietary assessment tools selected to measure intervention objectives, and how results are interpreted in key findings, are essential when examining children’s diets. Dietary assessment tools can be used to capture habitual or acute dietary intake as well as a variety of dietary outputs—foods and food groups consumed (e.g., fruits and vegetables), energy (calories), macronutrients (carbohydrates, fats and protein), micronutrients (vitamins and minerals), and dietary scores or quality indices (e.g., diet diversity, Healthy Eating Index).
  • 1.4K
  • 16 Dec 2022
  • Page
  • of
  • 2728
Featured Entry Collections
>>

Featured Reprints

>>
Encyclopedia of Digital Society, Industry 5.0 and Smart City
Encyclopedia of Engineering
Encyclopedia of Social Sciences
Encyclopedia of Medieval Royal Iconography
Academic Video Service
Feedback