Subject:
All Disciplines Arts & Humanities Biology & Life Sciences Business & Economics Chemistry & Materials Science Computer Science & Mathematics Engineering Environmental & Earth Sciences Medicine & Pharmacology Physical Sciences Public Health & Healthcare Social Sciences
Sort:
Hottest Latest Alphabetical (A-Z) Alphabetical (Z-A)
Type:
All Topic Review Biography
Topic Review
WDR45 Gene
WD repeat domain 45.
  • 429
  • 24 Dec 2020
Topic Review
WDR35 Gene
WD repeat domain 35.
  • 409
  • 24 Dec 2020
Topic Review
WDR19 Gene
WD repeat domain 19.
  • 334
  • 24 Dec 2020
Topic Review
WDFW Toxics in Biota Fish Monitoring
Fish are an important component of the Washington Department of Fish and Wildlife's (WDFW) Toxics in Biota Program, part of the Puget Sound Ecosystem Monitoring Program (PSEMP, recently renamed from PSAMP). Since 1989 fish indicator species have been used to monitor contamination of Puget Sound by chemicals such as poly-chlorinated biphenyls (PCBs), polycyclic aromatic hydrocarbons (PAHs), pesticides, and metals. English Sole, the first species studied for the Toxics in Biota Program, have been used for monitoring by WDFW since 1989. As of 2015 the program also monitors copper rockfish, quillback rockfish, brown rockfish, coho salmon, chinook salmon, Pacific herring, and Pacific staghorn sculpin. Exposure and effects of each contaminant are monitored for each species, and more in-depth studies of specific regions are performed if monitoring indicates a contamination problem. Geographical characteristics making Puget Sound especially susceptible to contaminants include funneling of fish through narrow inlets, restricted exchange of water, shallow sea floor sills, and freshwater inputs from urban sources. One of the largest sources of contaminants is stormwater runoff. During heavy rain events metals, persistent organic pollutants (POPs), and pesticides flow untreated into local waterways, streams, and lakes. Impervious surfaces such as roads provide a route for deposition of metals and POPs by cars and industrial emissions, before subsequent discharge into nearby water bodies. The highly urbanized coastline of southern Puget Sound results in stormwater runoff containing high concentrations of contaminants.
  • 259
  • 17 Oct 2022
Topic Review
WD40 Repeat
The WD40 repeat (also known as the WD or beta-transducin repeat) is a short structural motif of approximately 40 amino acids, often terminating in a tryptophan-aspartic acid (W-D) dipeptide. Tandem copies of these repeats typically fold together to form a type of circular solenoid protein domain called the WD40 domain.
  • 501
  • 23 Nov 2022
Topic Review
WD Repeat Domain 5 Inhibitors for Cancer Therapy
WDR5 is a conserved nuclear protein that scaffolds the assembly of epigenetic regulatory complexes and moonlights in functions ranging from recruiting MYC oncoproteins to chromatin to facilitating the integrity of mitosis. It is also a high-value target for anti-cancer therapies, with small molecule WDR5 inhibitors and degraders undergoing extensive preclinical assessment. WDR5 inhibitors were originally conceived as epigenetic modulators, proposed to inhibit cancer cells by reversing oncogenic patterns of histone H3 lysine 4 methylation—a notion that persists to this day.
  • 194
  • 15 Jan 2024
Topic Review
WBC and HBOT in Depression
Treatment with antidepressants is often insufficiently effective, especially in treatment-resistant depression. In such a situation, it is possible to change the drug, add a second antidepressant, or use pharmacological and non-pharmacological methods of augmenting the effect of pharmacotherapy. New methods that may fall into the scope of multi-module depression treatment as an augmentation of depression treatment are whole body cryotherapy (WBC) and hyperbaric oxygen treatment (HBOT). 545 records were selected and analyzed for these two treatments and finally three clinical trials were selected for analysis. 
  • 616
  • 22 Sep 2021
Topic Review
WBAN Authentication Protocols for Intra-BAN Tier
Telecare medical information system (TMIS) is a technology used in a wireless body area network (WBAN), which has a crucial role in healthcare services. TMIS uses wearable devices with sensors to collect patients’ data and transmit the data to the controller node via a public channel.
  • 667
  • 26 Aug 2022
Topic Review
Ways of Production of Bioactives and Their Impact
Plants are an inexhaustible source of bioactive compounds that have been used by men since ancient times as folk medicines and as preservatives of food. Medicinal plants have always been of interest to scientific research and to the chemical and pharmaceutical industries because of their multiple applications for their antioxidant, antibacterial, stimulative, and inhibitory properties.
  • 578
  • 06 May 2022
Topic Review
Ways of Light Energy Utilization in C4 Photosynthesis
Most C4 plants that naturally occur in tropical or subtropical climates, in high light environments, had to evolve a series of adaptations of photosynthesis that allowed them to grow under these conditions. Some mechanisms that function under changing light conditions, particularly in high light intensity, are universal and are also found in C3 plants. However, some are modified in C4 plants to provide more efficient CO2 assimilation. The close relationship between the light phase of photosynthesis and the enzymatic reactions in chloroplasts, and the associated demand for ATP and NADPH, results that in C4 plants the linear and cyclic electron transport operate in a different ratio in the chloroplasts of mesophyll (M) and bundle sheath (BS) cells. In addition, differences in the intensity of light reaching M and BS chloroplasts and in the thylakoid structure (granal and agranal) will affect the processes of the redistribution of excitation energy between photosystems and the dissipation of its excess. Therefore, it can be assumed that, in the M chloroplasts, because of increased incoming light energy, the mechanisms related to the dissipation of excess energy must function better than in BS chloroplasts to prevent photosystems from photoinhibition and, in consequence, from a decrease in ATP and NADPH. On the other hand, BS chloroplasts, which receive less light energy, must have better functioning mechanisms that allow for its efficient use.
  • 853
  • 06 Apr 2022
  • Page
  • of
  • 5495
Featured Entry Collections
>>

Featured Books

>>
Encyclopedia of Social Sciences
Encyclopedia of COVID-19
Encyclopedia of Fungi
Encyclopedia of Digital Society, Industry 5.0 and Smart City
ScholarVision Creations
Feedback