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All Topic Review Biography
Topic Review
3D Printed Nonlinear Musculoskeletal Actuator
A nature-inspired musculoskeletal-actuator system is developed using 3d printing for robotic applications. The actuator resembles the rigid segments and the soft-rigid interaction architecture found in limbless vertebrates such as snakes. The rigid segments provide an increase in the range of motion while maintaining structural durability and stability. The soft-rigid interactions provided a remarkable increase in energy transmission and storage, which enhanced the reliability of the musculoskeletal-actuator. Additionally, passive structural stiffness and damping control are achieved. Similar to a muscular system, our musculoskeletal-actuator is capable of increasing its stiffness and damping up to 100% and 60%, respectively, upon load lifting.
  • 672
  • 28 Mar 2022
Topic Review
3D Printed Silicone Meniscus Implants
Osteoarthritis of the knee with meniscal pathologies is a severe meniscal pathology suffered by the aging population worldwide. However, conventional meniscal substitutes are not 3D-printable and lack the customizability of 3D printed implants and are not mechanically robust enough for human implantation. Similarly, 3D printed hydrogel scaffolds suffer from drawbacks of being mechanically weak and as a result patients are unable to execute immediate post-surgical weight-bearing ambulation and rehabilitation. To solve this problem, we have developed a 3D silicone meniscus implant which is (1) cytocompatible, (2) resistant to cyclic loading and mechanically similar to native meniscus, and (3) directly 3D printable. The main focus of this study is to determine whether the purity, composition, structure, dimensions and mechanical properties of silicone implants are affected by the use of a custom-made in-house 3D-printer. We have used the phosphate buffer saline (PBS) absorption test, Fourier transform infrared (FTIR) spectroscopy, surface profilometry, thermo-gravimetric analysis (TGA), X-ray photoelectron spectroscopy (XPS), differential scanning calorimetry (DSC), and scanning electron microscopy (SEM) to effectively assess and compare material properties between molded and 3D printed silicone samples.
  • 762
  • 17 Apr 2021
Topic Review
3D Printers Implementation in the Medical Sector
3D printing application extends to various sectors, such as aerospace, construction, art, domestic, up to healthcare. It is in this domain that its adoption could offer technological solutions aimed at improving the individual life and guaranteeing organizational effectiveness. It emerges that the adoption of 3D printers within the medical sector also leads to a change in procedures and production activities.
  • 598
  • 15 Jun 2022
Topic Review
3D Printing
Three-dimensional (3D) printing technology holds great potential to fabricate complex constructs in the field of regenerative medicine. Researchers in the surgical fields have used 3D printing techniques and their associated biomaterials for education, training, consultation, organ transplantation, plastic surgery, surgical planning, dentures, and more. In addition, the universal utilization of 3D printing techniques enables researchers to exploit different types of hardware and software in, for example, the surgical fields. To realize the 3D-printed structures to implant them in the body and tissue regeneration, it is important to understand 3D printing technology and its enabling technologies.
  • 1.8K
  • 20 Apr 2021
Topic Review
3D Printing and Biomedical Applications
3D printing is gaining traction in the manufacturing industry, with the benefits of improving productivity and lowering both the cost and number of human-based faults. Given its enormous flexibility and capacity to modify and construct a range of simple to complicated geometries, 3D printing has altered production rates with process automation. 3D printing is swiftly transforming pharmaceutical production to achieve elevated quality therapeutic products with improved process sturdiness in bio-pharmaceutical product evolution, where there is a dependence on medicines manufacturing via conventional manufacturing procedures.
  • 741
  • 29 Sep 2021
Topic Review
3D Printing and Bioprinting for Cardiovascular Tissue Engineering
Recent decades have seen a plethora of regenerating new tissues in order to treat a multitude of cardiovascular diseases. Autografts, xenografts and bioengineered extracellular matrices have been employed in this endeavor. However, current limitations of xenografts and exogenous scaffolds to acquire sustainable cell viability, anti-inflammatory and non-cytotoxic effects with anti-thrombogenic properties underline the requirement for alternative bioengineered scaffolds. Herein, we sought to encompass the methods of biofabricated scaffolds via 3D printing and bioprinting, the biomaterials and bioinks recruited to create biomimicked tissues of cardiac valves and vascular networks. Experimental and computational designing approaches have also been included. Moreover, the in vivo applications of the latest studies on the treatment of cardiovascular diseases have been compiled and rigorously discussed.
  • 723
  • 03 Mar 2022
Topic Review
3D Printing and Classification of Microneedles
Microneedles are micron-sized devices that are used for the transdermal administration of a wide range of active pharmaceutics substances with minimally invasive pain. 3D-printing technologies that have the potential to revolutionize the manufacturing of microneedles. 3D-printed microneedles have applications in various fields, such as drug delivery, vaccine delivery, cosmetics, therapy, tissue engineering, and diagnostic devices. Microneedles are classified into five types, which include solid microneedles, hollow microneedles, coated microneedles, hydrogel-forming microneedles, and dissolving microneedles.
  • 1.2K
  • 12 Dec 2022
Topic Review
3D Printing and Implementation of Digital Twins
Fabricating objects with desired mechanical properties by utilizing 3D printing methods can be expensive and time-consuming, especially when based only on a trial-and-error test modus operandi. Digital twins (DT) can be proposed as a solution to understand, analyze and improve the fabricated item, service system or production line.  The current trends and limitations in DTs for additive manufacturing are summarized, in order to provide more insights for further research on DT systems.
  • 368
  • 21 Jul 2023
Topic Review
3D Printing and Nanotechnologies in Biofilms
Biofilms remain one of the most pervasive complications of the medical field, representing 50–70% of all nosocomial infections and up to 80% of total microbial infections. Since biofilms contain intricately small matrices, different microenvironments, and accumulations of biodiverse microorganisms of different resistances, these structures end up being difficult to target.
  • 342
  • 08 Oct 2023
Topic Review
3D Printing at Micro-Level
Laser-induced forward transfer (LIFT) and two-photon polymerization (TPP) have proven their abilities to produce 3D complex microstructures at an extraordinary level of sophistication. Indeed, LIFT and TPP have supported the vision of providing a whole functional laboratory at a scale that can fit in the palm of a hand. This is only possible due to the developments in manufacturing at micro- and nano-scales. In a short time, LIFT and TPP have gained popularity, from being a microfabrication innovation utilized by laser experts to become a valuable instrument in the hands of researchers and technologists performing in various research and development areas, such as electronics, medicine, and micro-fluidics. In comparison with conventional micro-manufacturing methods, LIFT and TPP can produce exceptional 3D components. To gain benefits from LIFT and TPP, in-detail comprehension of the process and the manufactured parts’ mechanical–chemical characteristics is required. 
  • 1.6K
  • 01 Jul 2021
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