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Topic Review
Applications of Gas Chromatography for Tricyclic Antidepressants Analysis
Tricyclic antidepressant drugs (TCAs) are a main category of antidepressants, which are widely used for the treatment of psychological disorders due to their low cost and their high efficiency. Therefore, there is a great demand for method development for the determination of TCAs in biofluids, especially for therapeutic drug monitoring. Gas chromatography (GC) was the first chromatographic technique implemented for this purpose. With the development in the field of sample preparation, many novel GC applications have been developed. 
  • 141
  • 05 Mar 2024
Topic Review
White Coat in the Domestic Horse
Traits such as shape, size, and color often influence the economic and sentimental value of a horse. Around the world, horses are bred and prized for the colors and markings that make their unique coat patterns stand out from the crowd. The underlying genetic mechanisms determining the color of a horse’s coat can vary greatly in their complexity.
  • 126
  • 05 Mar 2024
Topic Review
Artificial Intelligence Advancements in Cervical Cancer
Artificial intelligence has yielded remarkably promising results in several medical fields, namely those with a strong imaging component. Gynecology relies heavily on imaging since it offers useful visual data on the female reproductive system, leading to a deeper understanding of pathophysiological concepts. The applicability of artificial intelligence technologies has not been as noticeable in gynecologic imaging as in other medical fields. However, due to growing interest in this area, some studies have been performed with exciting results. From urogynecology to oncology, artificial intelligence algorithms, particularly machine learning and deep learning, have shown huge potential to revolutionize the overall healthcare experience for women’s reproductive health.
  • 188
  • 05 Mar 2024
Topic Review
Promoting Health among Children and Adolescents via Gamification
The rapid growth in digital technology usage among children and adolescents has highlighted the need for novel approaches to promote their physical and mental health. Promoting children and adolescents’ physical and mental health through gamified techniques, these interventions can provide an interactive and engaging platform for encouraging physical activity, promoting healthy nutrition, enhancing emotional regulation, and promoting mental health. The significance of this topic stems from the pervasive use of electronic games, beginning at a young age, which makes them popular educational tools.
  • 331
  • 05 Mar 2024
Topic Review
Experimental Approach to Silicon Heterojunction Tandem Solar Cells
A solar cell, or a photovoltaic (PV) cell, is an electrical device that converts light energy directly into electricity by the photovoltaic effect. There are different types of solar cells. Tandem solar cells could have a very good conversion efficiency in comparison with other types of solar cells. Tandem solar cells are considered the industry’s next step in photovoltaics due to their excellent conversion efficiency. A very good example is the perovskite absorber material that has been developed for efficient tandem solar cells. 
  • 182
  • 05 Mar 2024
Topic Review
Novel Biomarkers of Bone Metabolism
Bone represents a metabolically active tissue subject to continuous remodeling orchestrated by the dynamic interplay between osteoblasts and osteoclasts. These cellular processes are modulated by a complex interplay of biochemical and mechanical factors, which are instrumental in assessing bone remodeling. This comprehensive evaluation aids in detecting disorders arising from imbalances between bone formation and reabsorption. Osteoporosis, characterized by a reduction in bone mass and strength leading to heightened bone fragility and susceptibility to fractures, is one of the more prevalent chronic diseases. Some epidemiological studies, especially in patients with chronic kidney disease (CKD), have identified an association between osteoporosis and vascular calcification. Notably, low bone mineral density has been linked to an increased incidence of aortic calcification, with shared molecules, mechanisms, and pathways between the two processes. Certain molecules emerging from these shared pathways can serve as biomarkers for bone and mineral metabolism. Detecting and evaluating these alterations early is crucial, requiring the identification of biomarkers that are reliable for early intervention. While traditional biomarkers for bone remodeling and vascular calcification exist, they suffer from limitations such as low specificity, low sensitivity, and conflicting results across studies. In response, efforts are underway to explore new, more specific biomarkers that can detect alterations at earlier stages. 
  • 148
  • 05 Mar 2024
Topic Review
Connections between Intestinal Flora and Kynurenine Pathway
The intestinal flora has been the focus of numerous investigations recently, with inquiries not just into the gastrointestinal aspects but also the pathomechanism of other diseases such as nervous system disorders and mitochondrial diseases. Mitochondrial disorders are the most common type of inheritable metabolic illness caused by mutations of mitochondrial and nuclear DNA. Metabolites of the kynurenine pathway are linked to many disorders, such as depression, schizophrenia, migraine, and also diseases associated with impaired mitochondrial function. The kynurenine pathway includes many substances, for instance kynurenic acid and quinolinic acid. 
  • 93
  • 05 Mar 2024
Topic Review
Greenfield Investment and Green Economic Growth
The intensification of countries’ growth causes the depletion of natural resources, biodiversity degradation, ecological imbalances, damage, and disasters. The aggravation of ecological issues requires the development of mechanisms for simultaneous achievement of economic, social, and ecological goals. The energy sector is the core direction of economic decarbonization. Therefore, green economic growth requires economic development due to the extension of innovative technologies for renewable energies and relevant investment for that. The concept of “green economic growth” is linked to the paradigm of sustainable development and reflects economic growth considering the rational use of natural capital, prevents and reduces pollution and developed opportunities to improve social well-being due to providing carbon-neutral economy. The concept of “greenfield investment” is wider and complex definitions, the scholars define it as the investment on environmental, social and governance projects which aims to achieve sustainable development goals in long-term.
  • 184
  • 05 Mar 2024
Topic Review
Opportunities for Biodiversity Conservation via Urban Ecosystem Regeneration
Conservation traditionally focuses on at-risk species and relatively intact ecosystems. As the human population and our global impact have risen, many more species and ecosystems are at risk and fewer intact ecosystems remain, with urbanization being a major contributing factor. Cities and their inhabitants are here to stay, and the prevalence of urbanization, often in the vicinity of areas of high conservation value, requires reconsideration of the conservation value of urban ecosystems and urban green spaces.
  • 227
  • 05 Mar 2024
Topic Review
DL-SLICER
A novel artificial intelligence (AI)-driven city classification method which provides a homogeneous and unbiased result, employing visual and publicly accessible data focusing on factual circumstances and complex visual causalities. It offers a new perspective in the research domain by developing a deep learning (DL) tool that analyzes visual information from city satellite image patches.
  • 176
  • 05 Mar 2024
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