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Topic Review
Pigmented Purpuric Dermatoses
Pigmented purpuric dermatoses (PPD) encompass a group of chronic skin conditions characterized by the presence of petechiae, purpura, and pigmentation changes.
  • 218
  • 07 Mar 2024
Topic Review
The Host Response to Coccidioidomycosis
Coccidioidomycosis is an important fungal disease that is found in many desert regions of the western hemisphere.
  • 111
  • 07 Mar 2024
Topic Review
Tau Pathology in Alzheimer’s Disease and Down Syndrome
Individuals with Down syndrome (DS) exhibit an almost complete penetrance of Alzheimer’s disease (AD) pathology but are underrepresented in clinical trials for AD. The Tau protein is associated with microtubule function in the neuron and is crucial for normal axonal transport. In several different neurodegenerative disorders, Tau misfolding leads to hyper-phosphorylation of Tau (p-Tau), which may seed pathology to bystander cells and spread.
  • 178
  • 07 Mar 2024
Topic Review
Gastroesophageal Reflux Disease following Sleeve Gastrectomy
Obesity is associated with serious comorbidities and economic implications. Bariatric surgery, most commonly Roux-en-Y gastric bypass and sleeve gastrectomy, are effective options for weight loss and the improvement of obesity-related comorbidities. With the growing obesity epidemic, there has been a concomitant rise in bariatric surgeries, particularly in sleeve gastrectomy. Gastroesophageal reflux disease (GERD) is highly prevalent in obese individuals, can significantly impact quality of life and may lead to serious complications. Obesity and GERD both improve with weight loss.
  • 101
  • 07 Mar 2024
Topic Review
Safety Management in Industry 5.0 Manufacturing
Safety management is a priority to guarantee human-centered manufacturing processes in the context of Industry 5.0, which aims to realize a safe human–machine environment based on knowledge-driven approaches. The traditional approaches for safety management in the industrial environment include staff training, regular inspections, warning signs, etc. Despite the fact that proactive measures and procedures have exceptional importance in the prevention of safety hazards, human–machine–environment coupling requires more sophisticated approaches able to provide automated, reliable, real-time, cost-effective, and adaptive hazard identification in complex manufacturing processes.
  • 276
  • 07 Mar 2024
Topic Review
Oxidative Stress in Tumorigenesis and Progression
Oxidative stress refers to the imbalance between the production of reactive oxygen species (ROS) and the endogenous antioxidant defense system. Its involvement in cell senescence, apoptosis, and series diseases has been demonstrated. Advances in carcinogenic research have revealed oxidative stress as a pivotal pathophysiological pathway in tumorigenesis and to be involved in lung cancer, glioma, hepatocellular carcinoma, leukemia, and so on.
  • 118
  • 07 Mar 2024
Topic Review
Incorporation of Some Microalgae in Functional Food Products
Much attention has been given to the use of microalgae to produce functional foods that have valuable bioactive chemicals, including essential amino acids, polyunsaturated fatty acids, vitamins, carotenoids, fiber, and minerals. Microalgal biomasses are increasingly being used to improve the nutritional values of foods because of their unique nutrient compositions that are beneficial to human health. Their protein content and amino acid composition are the most important components. The microalgal biomass used in the therapeutic supplement industry is dominated by bio-compounds like astaxanthin, β-carotene, polyunsaturated fatty acids like eicosapentaenoic acid and docosahexaenoic acid, and polysaccharides such as β-glucan. The popularity of microalgal supplements is growing because of the health benefits of their bioactive substances. 
  • 129
  • 07 Mar 2024
Topic Review
Solar Thermal Technology in Buildings
Buildings account for a significant proportion of total energy consumption. The integration of renewable energy sources is essential to reducing energy demand and achieve sustainable building design. The use of solar energy has great potential for promoting energy efficiency and reducing the environmental impact of energy consumption in buildings.
  • 213
  • 07 Mar 2024
Topic Review
Mangrove Swamp Rice Production in Guinea-Bissau
Rice (Oryza sativa L. and O. glaberrima) is one of the most important staple foods on the Asian, African, and American continents. The rice crop grows primarily in the humid and seasonally dry tropics of the world, in most cases with irrigation or freshwater harvesting systems. The mangrove swamp rice production (MSRP) refers to rice cultivation in former mangrove soils that have been anthropogenically modified for rice production in west Africa.
  • 219
  • 07 Mar 2024
Topic Review
Laccase
Enzymes play an important role in numerous natural processes and are increasingly being utilized as environmentally friendly substitutes and alternatives to many common catalysts. Both horseradish peroxidase (HRP) and laccase are most often utilized for the formation of enzyme aggregates due to their ability to rapidly oxidize phenols, generating phenoxy radicals which undergo radical coupling to form biphenyl or phenyl ether linkages. 
  • 379
  • 07 Mar 2024
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