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Topic Review
Functionalism Versus Intentionalism
Functionalism versus intentionalism is a historiographical debate about the origins of the Holocaust as well as most aspects of the Third Reich, such as foreign policy. The debate on the origins of the Holocaust centres on essentially two questions: The terms were coined in a 1981 essay by the British Marxist historian Timothy Mason. Notable functionalists have included Timothy Mason, Raul Hilberg, Karl Schleunes, Christopher Browning, Hans Mommsen, Martin Broszat, Götz Aly, Yehuda Bauer and Zygmunt Bauman. Notable intentionalists have included Gerald Fleming, Karl Dietrich Bracher, Andreas Hillgruber, Klaus Hildebrand, Eberhard Jäckel, Gerhard Weinberg, Walter Laqueur, Saul Friedländer, Richard Breitman, Lucy Dawidowicz and Daniel Jonah Goldhagen.
  • 11.3K
  • 24 Nov 2022
Topic Review
Flood Prediction Using ML Models
Floods are among the most destructive natural disasters, which are highly complex to model. The research on the advancement of flood prediction models contributed to risk reduction, policy suggestion, minimization of the loss of human life, and reduction of the property damage associated with floods. To mimic the complex mathematical expressions of physical processes of floods, during the past two decades, machine learning (ML) methods contributed highly in the advancement of prediction systems providing better performance and cost-effective solutions. Due to the vast benefits and potential of ML, its popularity dramatically increased among hydrologists.Researchers through introducing novel ML methods and hybridizing of the existing ones aim at discovering more accurate and efficient prediction models. The main contribution of this paper is to demonstrate the state of the art of ML models in flood prediction and to give insight into the most suitable models. In this paper, the literature where ML models were benchmarked through a qualitative analysis of robustness, accuracy, effectiveness, and speed are particularly investigated to provide an extensive overview on the various ML algorithms used in the field. The performance comparison of ML models presents an in-depth understanding of the different techniques within the framework of a comprehensive evaluation and discussion. As a result, this paper introduces the most promising prediction methods for both long-term and short-term floods. Furthermore, the major trends in improving the quality of flood prediction models are investigated. Among them, hybridization, data decomposition, algorithm ensemble, and model optimization are reported as the most effective strategies for the improvement of ML methods. This survey can be used as a guideline for hydrologists as well as climate scientists in choosing the proper ML method according to the prediction task.
  • 11.3K
  • 04 Jan 2023
Topic Review
Ethereum
Ethereum is a decentralized, open-source blockchain with smart contract functionality. Ether (ETH or Ξ) is the native cryptocurrency of the platform. Among cryptocurrencies, Ether is second only to Bitcoin in market capitalization. Ethereum was conceived in 2013 by programmer Vitalik Buterin. Additional founders of Ethereum included Gavin Wood, Charles Hoskinson, Anthony Di Iorio and Joseph Lubin. In 2014, development work began and was crowdfunded, and the network went live on 30 July 2015. Ethereum allows anyone to deploy permanent and immutable decentralized applications onto it, with which users can interact. Decentralized finance (DeFi) applications provide a broad array of financial services without the need for typical financial intermediaries like brokerages, exchanges, or banks, such as allowing cryptocurrency users to borrow against their holdings or lend them out for interest. Ethereum also allows users to create and exchange NFTs, which are unique tokens representing ownership of an associated asset or privilege, as recognized by any number of institutions. Additionally, many other cryptocurrencies utilize the ERC-20 token standard on top of the Ethereum blockchain and have utilized the platform for initial coin offerings. A series of upgrades called Ethereum 2.0 includes a transition to proof of stake and aims to increase transaction throughput by using sharding.
  • 11.2K
  • 20 Oct 2022
Topic Review
Macroplastic
The term macroplastics describes plastic items with a diameter ≥ 5 mm. With this size definition macroplastics can be directly distinguished from microplastics (diameter < 5 mm). Plastic items ≥ 5 mm are commonly considered to be macroplastics once they are released into the environment. Other terminologies used synonymous to macroplastic are “macro litter", “anthropogenic litter”, “plastic litter”, “marine litter”, “marine plastic” and “plastic debris”. 
  • 11.2K
  • 09 Oct 2020
Topic Review
Water Quality Degradation
Water quality degradation is happened through the natural processes that influence the surface water and groundwater quality by various sources such as climate changes, natural disasters, geological factors, soil-matrix, and hyporheic exchange. Water could also be contaminated by anthropogenic factors. Anthropogenic pollutants are substances caused by human actions, mostly resulting from land-use practices. 
  • 11.2K
  • 05 Feb 2022
Topic Review
The Tryptophan-Kynurenine Metabolic Pathway
Tryptophan (TRP) is one of the essential amino acids, which participates in protein synthesis. The tryptophan’s main metabolic route is the kynurenine pathway (KP) through which approximately 90-95% of TRP degrades into nicotinamide adenine dinucleotide (NAD+) and other bioactive metabolites. The appropriate amount of NAD+ is essential to maintain the operation and the viability of cells. The other molecules are neurotoxic, neuroprotective, oxidant, antioxidant, and/or immune modifiers. They play an important role in the function of the brain and the peripheral tissues. The change in the levels of the bioactive molecules is considered to contribute to the development of a wide range of illnesses from cancer to immunologic, neurodegenerative, and psychiatric diseases.
  • 11.1K
  • 10 Aug 2021
Topic Review
Hormonal Breast Enhancement
Hormonal breast enhancement or augmentation is a highly experimental potential medical treatment for the breasts in which hormones or hormonal agents such as estrogen, progesterone, growth hormone (GH), and insulin-like growth factor 1 (IGF-1) are utilized or manipulated to produce breast enlargement in women. It is a possible alternative or supplement to surgical breast augmentation with breast implants or fat transfer and other means of medical breast enlargement. In addition to pharmaceuticals, some herbal breast enlargement supplements contain phytoestrogens such as 8-prenylnaringenin (found in hops) and miroestrol (a constituent of Pueraria mirifica) and thus may be regarded as a form of hormonal breast enhancement. However, evidence of their effectiveness, as well as safety data, are lacking.
  • 11.0K
  • 24 Oct 2022
Topic Review
Overhead Camshaft
Overhead camshaft, commonly abbreviated to OHC, is a valvetrain configuration which places the camshaft of an internal combustion engine of the reciprocating type within the cylinder heads ("above" the pistons and combustion chambers) and drives the valves or lifters in a more direct manner compared with overhead valves (OHV) and pushrods.
  • 10.9K
  • 21 Nov 2022
Topic Review
Relative Hour (Jewish Law)
Relative hour (Hebrew singular: shaʿah zǝmanit / שעה זמנית; plural: shaʿot - zǝmaniyot / שעות זמניות), sometimes called halachic hour, seasonal hour and variable hour, is a term used in rabbinic Jewish law that assigns 12 hours to each day and 12 hours to each night, all throughout the year. A relative hour has no fixed radical, but changes with the length of each day - depending on summer (when the days are long and the nights are short), and on winter (when the days are short and the nights are long). Even so, in all seasons a day is always divided into 12 hours, and a night is always divided into 12 hours, which inevitably makes for a longer hour or a shorter hour. All of the hours mentioned by the Sages in either the Mishnah or Talmud, or in other rabbinic writings, refer strictly to relative hours. Another feature of this ancient practice is that, unlike the standard modern 12-hour clock that assigns 12 o'clock pm for noon time, in the ancient Jewish tradition noon time was always the sixth hour of the day, whereas the first hour began with the break of dawn, by most exponents of Jewish law, and with sunrise by the Vilna Gaon and Rabbi Hai Gaon. 12:o'clock am (midnight) was also the sixth hour of the night, whereas the first hour of the night began when the first three stars appeared in the night sky.
  • 10.9K
  • 19 Oct 2022
Topic Review
Human Eye Color
Eye color is a polygenic phenotypic character and is determined by the amount and type of pigments in the eye's iris. Humans and other animals have many phenotypic variations in eye color, as blue, brown, gray, green and others. These variations constitute phenotypic traits. The genetics of eye color are complicated, and color is determined by multiple genes. Some of the eye-color genes include EYCL1 (a green/blue eye-color gene located on chromosome 19), EYCL2 (a brown eye-color gene) and EYCL3 (a brown/blue eye-color gene located on chromosome 15). The once-held view that blue eye color is a simple recessive trait has been shown to be wrong. The genetics of eye color are so complex that almost any parent-child combination of eye colors can occur. In human eyes, these variations in color are attributed to varying ratios of eumelanin produced by melanocytes in the iris. The brightly colored eyes of many bird species are largely determined by other pigments, such as pteridines, purines, and carotenoids. Three main elements within the iris contribute to its color: the melanin content of the iris pigment epithelium, the melanin content within the iris stroma, and the cellular density of the iris stroma. In eyes of all colors, the iris pigment epithelium contains the black pigment, eumelanin. Color variations among different irides are typically attributed to the melanin content within the iris stroma. The density of cells within the stroma affects how much light is absorbed by the underlying pigment epithelium. OCA2 gene polymorphism, close to proximal 5′ regulatory region, explains most human eye-color variation.
  • 10.8K
  • 05 Dec 2022
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