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Topic Review
Genome Organization
In higher-order organisms, the genome is assembled into a protein-dense structure called chromatin. Chromatin is spatially organized in the nucleus through hierarchical folding, which is tightly regulated both in cycling cells and quiescent cells. Assembly and folding are not one-time events in a cell’s lifetime; rather, they are subject to dynamic shifts to allow changes in transcription, DNA replication, or DNA damage repair.  Chromatin is regulated at many levels and recent tools have permitted the elucidation of specific factors involved in the maintenance and regulation of the three-dimensional (3D) genome organization.
  • 3.3K
  • 14 Apr 2021
Topic Review
2010–14 Portuguese Financial Crisis
2010–14 Portuguese financial crisis was part of the more wider downturn of the Portuguese economy that started in 2001 and possibly ended in 2016–17. The period from 2010 to 2014 was probably the hardest and more challenging part of the entire economic crisis; this period includes the 2011–14 international bailout to Portugal and was marked by an intense austerity policy, intenser than in any other period of the wider 2001–17 crisis. Economic growth stalled in Portugal in 2001–02; following years of internal economic crisis, the (international) Great Recession started to hit Portugal in 2008 and eventually led to the country being unable to repay or refinance its government debt without the assistance of third parties. To prevent an insolvency situation in the debt crisis, Portugal applied in April 2011 for bail-out programs and drew a cumulated €78.0 billion from the International Monetary Fund (IMF), the European Financial Stabilisation Mechanism (EFSM), and the European Financial Stability Facility (EFSF). Portugal leaved bailout in May 2014, the same year that positive economic growth re-appeared following three years of recession. The government achieved a 2.1% budget deficit in 2016 (the lowest since the restoration of democracy in 1974) and in 2017 the economy grew 2.7% (the highest growth rate since 2000). Greece and Ireland also went into a debt crisis in 2010. Together these debt crisis of these three countries marked the start of the European sovereign debt crisis.
  • 3.3K
  • 06 Oct 2022
Topic Review
Sustainable Consumer Behavior
Sustainable Consumer Behavior, namely a new sustainable consumer model, refers to major shifts in buying and consumption habits. Nevertheless, these shifts were lagging as consumers resisted change in the comfort of old habits. This comfort was shaken up by the COVID-19 outbreak that forced us to rethink every aspect of our lives. Therefore, this crisis context seems the perfect opportunity to shift towards the sustainable consumer model.
  • 3.3K
  • 09 Jun 2021
Topic Review
Saltation
In biology, saltation (from la saltus 'leap, jump') is a sudden and large mutational change from one generation to the next, potentially causing single-step speciation. This was historically offered as an alternative to Darwinism. Some forms of mutationism were effectively saltationist, implying large discontinuous jumps. Speciation, such as by polyploidy in plants, can sometimes be achieved in a single and in evolutionary terms sudden step. Evidence exists for various forms of saltation in a variety of organisms.
  • 3.3K
  • 29 Sep 2022
Topic Review
Groundwater Withdrawal-Induced Land Subsidence
Land subsidence is probably one of the most evident environmental effects of groundwater pumping. Globally, freshwater demand is the leading cause of this phenomenon. Land subsidence induced by aquifer system drainage can reach total values of up to 14.5 m. The spatial extension of this phenomenon is usually extensive and is often difficult to define clearly. Aquifer compaction contributes to many socio-economic effects and high infrastructure-related damage costs. Currently, many methods are used to analyze aquifer compaction. These include the fundamental relationship between groundwater head and groundwater flow direction, water pressure and aquifer matrix compressibility. Such solutions enable satisfactory modelling results. However, further research is needed to allow more efficient modelling of aquifer compaction. Recently, satellite radar interferometry (InSAR) has contributed to significant progress in monitoring and determining the spatio-temporal land subsidence distributions worldwide. Therefore, implementation of this approach can pave the way to the development of more efficient aquifer compaction models. This entry presents a comprehensive review of models used to predict land surface displacements caused by rock mass drainage, as well as (2) recent advances and (3) a summary of InSAR implementation over recent years to support the aquifer compaction modelling process. Therefore, the study presented would be of benefit to readers who are interested in the topic of interaction between the human population and the hydrogeological system in different regions. The research presented allows readers to better understand the factors, developments and effects of groundwater drainage and thus facilitate large - scale risk assessment and preventive planning.
  • 3.3K
  • 27 Oct 2020
Topic Review
Rotating Packed Beds
In this study, a comprehensive review was conducted of the process intensification equipment used for gas absorption processes, which are known as rotating packed beds (RPB) or HiGee contactors. Using centrifugal acceleration in RPBs intensifies the MT coefficient, and this leads to a reduction in the packing volume and energy consumption in comparison with packed beds. The gas velocity and flow area change radially in RPBs; therefore, MT coefficients change from point to point in contactors, but there is no general theory for this, and the prediction of MT coefficients in RPBs is theoretically complicated.
  • 3.3K
  • 11 Aug 2021
Topic Review
Malaysia Waste Management Practices
The three main municipalities of Malaysia, Kuala Lumpur, Penang, and Melaka, were discussed in their actions in household waste management practices and strategies in social, economy, information technology, and governance to achieve success for a better sustainability of the environment.
  • 3.3K
  • 06 Jun 2022
Topic Review
Android Malware Detection Using ML
This systematic review discussed ML-based Android malware detection techniques. It critically evaluated 106 carefully selected articles and highlighted their strengths and weaknesses as well as potential improvements. The ML-based methods for detecting source code vulnerabilities were also discussed, because it might be more difficult to add security after the app is deployed. Therefore, this paper aimed to enable researchers to acquire in-depth knowledge in the field and to identify potential future research and development directions.
  • 3.3K
  • 19 Aug 2021
Topic Review
Fungi–Nematode Interactions
Fungi and nematodes are among the most abundant organisms in soil habitats. They provide essential ecosystem services and play crucial roles for maintaining the stability of food-webs and for facilitating nutrient cycling. As two of the very abundant groups of organisms, depending on the specific species, fungi and nematodes interact with each other in multiple ways either directly or indirectly. Directly, they can interact with each other mutualistically to helping each other survive and reproduce, antagonistically to cause damage and/or kill each other, and as commensals. Indirectly, they may be interact with each other through other organisms. Both biotic and abiotic factors can impact the direction and magnitude of fungal-nematode interactions.
  • 3.3K
  • 22 Oct 2020
Topic Review
Water Quality Monitoring
Monitoring water quality is an essential tool for the control of pollutants and pathogens that can cause damage to the environment and human health. However, water quality analysis is usually performed in laboratory environments, often with the use of high-cost equipment and qualified professionals. With the progress of nanotechnology and the advance in engineering materials, several studies have shown, in recent years, the development of technologies aimed at monitoring water quality, with the ability to reduce the costs of analysis and accelerate the achievement of results for management and decision-making.
  • 3.3K
  • 13 May 2022
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