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Topic Review
Impedimetric Sensing
The COVID-19 pandemic revealed a pressing need for the development of sensitive and low-cost point-of-care sensors for disease diagnosis. The standard of care for COVID-19 is quantitative reverse transcriptase polymerase chain reaction (qRT-PCR). This method is sensitive, but takes time, effort, and requires specialized equipment and reagents to be performed correctly. This make it unsuitable for widespread, rapid testing and causes poor individual and policy decision-making. Rapid antigen tests (RATs) are a widely used alternative that provide results quickly but have low sensitivity and are prone to false negatives, particularly in cases with lower viral burden. Electrochemical sensors have shown much promise in filling this technology gap, and impedance spectroscopy specifically has exciting potential in rapid screening of COVID-19. Due to the data-rich nature of impedance measurements performed at different frequencies, this method lends itself to machine-leaning (ML) algorithms for further data processing.
  • 540
  • 16 Feb 2023
Topic Review
The Cold Spray Method
The cold, thermal spraying technology “Cold Spray” is a method of processing particles in a solid state. Research conducted through cold spray technology has seen a significant improvement in material properties; when processing the particles in a solid state, they adhere to the surface instead of eroding it. Cold spraying has proven to be an effective technique for improving material properties, as confirmed by its integration into different fields and industries, becoming competitive by being the only method for depositing particles below their melting point.
  • 408
  • 15 Feb 2023
Topic Review
Sensing and Automation Technologies for Ornamental Crops
The ornamental crop industry is an important contributor to the economy in the United States. The industry has been facing challenges due to continuously increasing labor and agricultural input costs. Sensing and automation technologies have been introduced to reduce labor requirements and to ensure efficient management operations. Applications of sensors, computer vision, artificial intelligence (AI), machine learning (ML), Internet-of-Things (IoT), and robotic technologies are reported. Some advanced technologies, including 3D cameras, enhanced deep learning models, edge computing, radio-frequency identification (RFID), and integrated robotics used for other cropping systems, are also discussed as potential prospects. Advanced sensing, AI and robotic technologies are critically needed for the nursery crop industry. Adapting these current and future innovative technologies will benefit growers working towards sustainable ornamental nursery crop production.
  • 1.1K
  • 15 Feb 2023
Topic Review
Artificial Intelligence Enabled Chemical Process Intensification
An overview of the application of AI techniques is provided, in particular machine learning, in chemical design, synthesis, and process optimization over the past years. The application of AI for structure-function relationship analysis, synthetic route planning, and automated synthesis is highly highlighted. 
  • 688
  • 15 Feb 2023
Topic Review
Fuel Cell Heavy-Duty Vehicle
Long-haul heavy-duty vehicles, including trucks and coaches, contribute to a substantial portion of the modern-day European carbon footprint and pose a major challenge in emissions reduction due to their energy-intensive usage. Depending on the hydrogen fuel source, the use of fuel cell electric vehicles (FCEV) for long-haul applications has shown significant potential in reducing road freight CO2 emissions until the possible maturity of future long-distance battery-electric mobility. Fuel cell heavy-duty (HD) propulsion presents some specific characteristics, advantages and operating constraints, along with the notable possibility of gains in powertrain efficiency and usability through improved system design and intelligent onboard energy and thermal management. 
  • 1.7K
  • 14 Feb 2023
Topic Review
Radiofrequency-Electromagnetic Fields Exposure
The interaction of electromagnetic fields (EMF) with living tissues or manufactured objects can produce different effects on these exposed entities. In different circumstances, these fields are used daily in various friendly applications. Applications of non-ionizing RF-EMF, frequencies from 100 kHz to 300 GHz have continuously increased. This involves medicine (e.g., magnetic resonance imaging and RF ablation), manufacturing (e.g., heaters and solders), home usages (e.g., child video display unit and Wi-Fi), protection and navigation (e.g., radar and RFID) and particularly in telecommunications (e.g., TV transmitting and mobile phones). This growth signifies that great amounts of the population are undergoing exposure to RF(radiofrequency)-EMF and worry has been inflated concerning public health concerns due to such exposure.
  • 537
  • 14 Feb 2023
Topic Review
Enhance the Efficiency of Thermophilic Anaerobic Digestion
Thermophilic anaerobic digestion (TAD) technology has been adopted worldwide mainly due to it being a pathogen-free process in addition to the enhanced biogas yield and short hydraulic retention time (HRT). Taking the high metabolic rate of the thermophilic microbial community with highly efficient enzymatic systems into consideration, thermophiles are being widely explored as efficient inocula for lignocellulosic biomass (LCB) degradation and improved biomethane production. The advantages of TAD over mesophilic anaerobic digestion (MAD), including improved kinetics, efficient degradation of organic matter, and economic and environmental sustainability, make it one of the best strategies to be operated at moderately high temperatures. 
  • 293
  • 14 Feb 2023
Topic Review
Loosening and Preload Loss of Threaded Connections
Threaded fasteners are vastly used in the industry due to ease of mounting and dismounting and flexibility of design. Nonetheless, several researchers indicate that most failures recorded on nearly any kind of machinery and vehicles are initiated at fasteners. Loosening is a process of rotation of the bolt in a direction opposite to the tightening. This can cause a loss of preload (tension created in the screw shank upon tightening) which can cause failures in the machinery. 
  • 791
  • 14 Feb 2023
Topic Review
Renewable Energy and Energy Storage Systems
The use of fossil fuels has contributed to climate change and global warming, which has led to a growing need for renewable and ecologically friendly alternatives to these. It is accepted that renewable energy sources are the ideal option to substitute fossil fuels in the near future. Significant progress has been made to produce renewable energy sources with acceptable prices at a commercial scale, such as solar, wind, and biomass energies. Hybrid renewable energy systems are needed with good energy management to balance the various renewable energy sources’ production/consumption/storage.
  • 1.1K
  • 14 Feb 2023
Topic Review
Fundamentals of Gut-on-a-Chip Models
Recent progress in microfluidic technology has made it possible to mimic characteristics and responses of the human gut as seen in vivo. In the past decade, researchers have enhanced organ-on-a-chip technology (GOC) models by incorporating sensors and biometers to control parameters that mimic the human gut. Most in vitro GOC models depend upon 2D cell culture models, whereby the intestinal epithelial cell lines (i.e., human colon adenocarcinoma (Caco-2) or human colorectal adenocarcinoma cell line with epithelial morphology (HT-29 cells)) are grown on extracellular matrix (ECM)-coated porous membranes inside Transwell systems or 2D monoculture plates. These models are often used to study the barrier functions and drug absorption; hence they are primarily applied in the pharmaceutical industry. 2D Transwell culture systems are simple and can be used for short-term observations; however, they fail to recapitulate the 3D structures and interactions of the native tissue such as microstructures (i.e., microvilli), mucus production, peristaltic motion, drug metabolism, etc. Another challenge with conventional models is due to the static nature the integration of commensal microbiomes, such as bacteria (i.e., E. coli) due to overgrowth and contamination of the system. To appropriately study the human gut’s physiology, pharmacology or pathology, the system used must recreate the 3D structures and microenvironment of the human gut. This can be achieved by using microfluidic platforms and incorporating live cells, thereby creating a 3D model with dynamic cell culture, and overcoming challenges such as microbial overgrowth. The most common GOC model structure has two channels (upper and lower layer), separated by a porous semipermeable membrane, which depicts the separation between the intestinal lumen and the vasculature. Furthermore, one of the two microchannels represents the lumen of the human gut. This channel aligns with the gut epithelial cells (i.e., IECs). The other channel represents the blood vessels and therefore aligns with vascular endothelial cells. The role of the semipermeable membrane is to facilitate the transport of soluble molecules and nutrients between the gut and the blood vessels.
  • 501
  • 13 Feb 2023
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