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Topic Review
Biography
Topic Review
Lifestyle and Hepatocellular Carcinoma
Liver cancer remains a global health challenge, and while infection by hepatitis B virus and hepatitis C virus are the main risk factors for hepatocellular carcinoma (HCC) development, non-alcoholic steatohepatitis is associated with metabolic syndrome or diabetes mellitus is becoming a more frequent risk factor.
492
07 Jan 2022
Topic Review
Current Helicobacter Pylori Diagnostics
Helicobacter pylori (H. pylori) is one of the most common human pathogens and a leading etiological factor for various gastroduodenal diseases, including chronic gastritis, peptic ulcers, gastric adenocarcinoma, and MALT lymphoma. According to the latest systematic review with meta-analysis, 44.3% (95% CI: 40.9–47.7) of the global population are infected with this microorganism. Timely diagnosis and subsequent eradication of H. pylori in adults allows one to resolve inflammatory changes in the gastric mucosa and prevent the development of precancerous conditions (atrophic gastritis and intestinal metaplasia).
492
26 Aug 2021
Topic Review
Osteoporosis/Sarcopenia in Chronic Liver Disease
The prevalence of osteoporosis and sarcopenia is significantly higher in patients with liver disease than in those without liver disease and osteoporosis and sarcopenia negatively influence morbidity and mortality in liver disease.
491
27 Apr 2021
Topic Review
Wnt/β-Catenin Signaling Pathway in Hepatocellular Carcinoma
Hepatocellular carcinoma (HCC) is a major cause of cancer death worldwide due to its high rates of tumor recurrence and metastasis. Aberrant Wnt/β-catenin signaling has been shown to play a significant role in HCC development, progression and clinical impact on tumor behavior.
490
17 Jan 2023
Topic Review
The Melanocortin System in Inflammatory Bowel Diseases
The melanocortin system is a complex set of molecular mediators and receptors involved in many physiological and homeostatic processes. These include the regulation of melanogenesis, steroidogenesis, neuromodulation and the modulation of inflammatory processes. In the latter context, the system has assumed importance in conditions of chronic digestive inflammation, such as inflammatory bowel diseases (IBD), in which numerous experiences have been accumulated in mouse models of colitis.
487
28 Sep 2023
Topic Review
Pancreatitis in Pregnancy
Acute and chronic pancreatitis, until observed incidentally in pregnancy. Particularly severe complications for the mother and fetus may be a consequence of acute pancreatitis. Therefore, it is important to know more about the diagnostic and therapeutic possibilities of pancreatic diseases in the course of pregnancy.
486
23 Dec 2022
Topic Review
Computer-Aided Polyp Detection
Artificial intelligence (AI) applied to medicine is here to stay. In gastroenterology, AI computer vision applications have been stated as a research priority. The two main AI system categories are computer-aided polyp detection (CADe) and computer-assisted diagnosis (CADx). CADe can detect previously unrecognized lesions and serve as “a second set of eyes” by continuously monitoring mechanisms. Furthermore, these systems may help to reduce in-day variations in ADRs due to operator fatigue.
485
20 Apr 2023
Topic Review
Role of Melatonin in the Pathogenesis of NAFLD
Endogenous melatonin, an indoleamine hormone synthesized by the pineal gland mainly at night, is a powerful chronobiotic that probably regulates metabolic processes and has antioxidant, anti-inflammatory, and genomic effects. Extrapineal melatonin has been found in various tissues and organs, including the liver, pancreas, and gastrointestinal tract, where it likely maintains cellular homeostasis. Melatonin exerts its effects on NAFLD at the cellular, subcellular, and molecular levels, affecting numerous signaling pathways.
482
25 Jun 2023
Topic Review
Diagnostic Methods in
H. pylori
Infection
Helicobacter pylori (H. pylori) develops potentially life-threatening conditions in adults if not appropriately treated. Helicobacter pylori is a common human pathogen that was first described in the stomach many years ago.
481
11 Jan 2023
Topic Review
Endoscopic Ultrasound for Gastrointestinal Stromal Tumours
Gastrointestinal Stromal Tumors (GISTs) are subepithelial lesions (SELs) that commonly develop in the gastrointestinal tract. GISTs, unlike other SELs, can exhibit malignant behavior, so differential diagnosis is critical to the decision-making process. Endoscopic ultrasound (EUS) is considered the most accurate imaging method for diagnosing and differentiating SELs in the gastrointestinal tract by assessing the lesions precisely and evaluating their malignant risk.
479
22 Feb 2023
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