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Topic Review
Cardiomyopathies
Cardiomyopathies are defined as cardiac diseases, in which the heart muscle is affected showing functional and structural defects.
  • 1.1K
  • 04 Feb 2021
Topic Review
Biomedical Applications of Plant-Mediated Zinc Oxide Nanoparticles
Zinc oxide nanoparticles have become one of the most popular metal oxide nanoparticles and recently emerged as a promising potential candidate in the fields of optical, electrical, food packaging, and biomedical applications due to their biocompatibility, low toxicity, and low cost. They have a role in cell apoptosis, as they trigger excessive reactive oxygen species (ROS) formation and release zinc ions (Zn2+) that induce cell death. The zinc oxide nanoparticles synthesized using the plant extracts appear to be simple, safer, sustainable, and more environmentally friendly compared to the physical and chemical routes. These biosynthesized nanoparticles possess strong biological activities and are in use for various biological applications in several industries. Initially, the present review discusses the synthesis and recent advances of zinc oxide nanoparticles from plant sources (such as leaves, stems, bark, roots, rhizomes, fruits, flowers, and seeds) and their biomedical applications (such as antimicrobial, antioxidant, antidiabetic, anticancer, anti-inflammatory, photocatalytic, wound healing, and drug delivery), followed by their mechanisms of action involved in detail. 
  • 1.1K
  • 21 Oct 2021
Topic Review
Natural Photosensitizers in Photodynamic Therapy
Photodynamic therapy (PDT) is a therapy for the treatment of many diseases, including cancer. This therapy uses a combination of a photosensitizer (PS), light irradiation of appropriate length and molecular oxygen. The photodynamic effect kills cancer cells through apoptosis, necrosis, or autophagy of tumor cells.
  • 1.1K
  • 29 Mar 2022
Topic Review
Machine Learning and Artificial Intelligence
Machine learning (ML) is a type of artificial intelligence (AI) consisting of algorithmic approaches that enable machines to solve problems deprived of explicit computer programming. 
  • 1.1K
  • 28 Apr 2023
Topic Review
Angiogenesis
Angiogenesis is an active process, regulating new vessel growth, and is crucial for the survival and growth of tumours next to other complex factors in the tumour microenvironment. We present possible molecular imaging approaches for tumour vascularisation and vitality, focusing on radiopharmaceuticals (tracers). Molecular imaging in general has become an integrated part of cancer therapy, by bringing relevant insights on tumour angiogenic status.
  • 1.1K
  • 16 Jun 2021
Biography
Carol Gilligan
Carol Gilligan (/ˈɡɪlɪɡən/; born November 28, 1936) is an American feminist, ethicist, and psychologist best known for her work on ethical community and ethical relationships. Gilligan is a professor of Humanities and Applied Psychology at New York University and was a visiting professor at the Centre for Gender Studies and Jesus College at the University of Cambridge until 2009. She is k
  • 1.1K
  • 21 Nov 2022
Topic Review
Medicinal Value of Black Mulberry
Roughly 100 species of Morus have been described, such as Morus alba (white mulberry), Morus rubra (red mulberry), and Morus nigra (black mulberry). The mulberry plant is monoecious or dioecious, reaching up to 10–12 m in height. Morus nigra (Moraceae family) is commonly distributed in Asia, Africa, Europe, and America. Given its therapeutic properties, the leaves, root barks, branches, and fruits are traditionally used in medicinal preparations to manage diabetes mellitus, atherosclerosis, hyperlipidemia, and hypertension. Various extracts of mulberry leaves were studied over the years, investigating their bioactive compounds’ pharmaceutical in public health concerns, such as diabetes, hepatic diseases, and cardiovascular diseases. This entry is based on a literature review and highlights the beneficial and therapeutic action of black mulberry extracts and their confirmed or hypothesized mechanism of action in diabetes, hepatic disorders, and cardiovascular disease, as indicated by the results of in vivo and in vitro studies, on cell lines, human and animal models.
  • 1.1K
  • 10 May 2021
Topic Review
Advanced Glycation End Products and Cardiovascular Disease
Epidemiological studies demonstrate the role of early and intensive glycemic control in the prevention of micro and macrovascular disease in both type 1 and type 2 diabetes mellitus (DM). Hyperglycemia elicits several pathways related to the etiopathogenesis of cardiovascular disease (CVD), including the generation of advanced glycation end products (AGEs). 
  • 1.1K
  • 11 Mar 2022
Topic Review
Augmented, Virtual and Mixed Reality in Dentistry
Augmented, Virtual and Mixed Reality can represent a useful aids for Dentistry. Augmented Reality can be used to add digital data to real life clinical data. Clinicians can apply Virtual Reality for a digital wax-up that provides a pre-visualization of the final post treatment result. In addition, both these technologies may also be employed to eradicate dental phobia in patients and further enhance patient’s education. Similarly, they can be used to enhance communication between the dentist, patient, and technician. Artificial Intelligence and Robotics can also improve clinical practice. Artificial Intelligence is currently developed to improve dental diagnosis and provide more precise prognoses of dental diseases, whereas Robotics may be used to assist in daily practice. 
  • 1.1K
  • 07 Feb 2022
Topic Review
Chinese Herbal Medicines for Sepsis Treatment
Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection; the pathophysiology of sepsis is complex. The incidence of sepsis is steadily increasing, with worldwide mortality ranging between 30% and 50%. Current treatment approaches mainly rely on the timely and appropriate administration of antimicrobials and supportive therapies, but the search for pharmacotherapies modulating the host response has been unsuccessful. Chinese herbal medicines, i.e., Chinese patent medicines, Chinese herbal prescriptions, and single Chinese herbs, play an important role in the treatment of sepsis through multicomponent, multipathway, and multitargeting abilities and have been officially recommended for the management of COVID-19.
  • 1.1K
  • 01 Nov 2021
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