Topic Review
Applications of 3D Printing in Cosmetics
3D printing (3DP) is a manufacturing technology that produces 3D objects from a design file using layer-by-layer deposition of material. It has already found applications in the healthcare and pharmaceutical industries. There are potential uses for 3DP in the cosmetic field. 
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  • 22 Nov 2022
Topic Review
Biomedical Applications of Electrospun Graphene Oxide
Graphene is an allotrope of carbon and is made up of sp2-bonded carbon atoms placed in a two-dimensional honeycomb lattice. Graphite consists of stacked layers of graphene. Due to the distinctive structural features as well as excellent physico-chemical and electrical conductivity, graphene allows remarkable improvement in the performance of electrospun nanofibers (NFs), which results in the enhancement of promising applications in NF-based sensor and biomedical technologies. 
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  • 22 Nov 2022
Topic Review
Evolution of the Vitamin D Receptor
The evolution of the vitamin D receptor started millions of years ago, with earliest evidence of the receptor in existing organisms tracing back to the sea lamprey (Petromyzon marinus). The vitamin D receptor is an example of a nuclear receptor, which binds vitamin D, and modulates the transcription of various target genes appropriately. Early in the history of life on Earth, nuclear receptors would have been selected for due to the strong pressure for organisms to respond to their environment. This eventually lead to the evolution of nuclear receptor families, such as the NR1H and NR1I families, capable of binding nutritional ligands and modulating transcription appropriately. Each of these families host a variety of receptors, including the vitamin D receptor, but all are thought to have originated from one ancestral receptor. Through major gene duplications and variable selective pressures, the various receptors within these families evolved, each one accommodating cholesterol derivatives, such as oxysterols, bile acids, and vitamin D.
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  • 21 Nov 2022
Topic Review
Post-transition Metal
Post-transition metals are a set of metallic elements in the periodic table located between the transition metals to their left, and the metalloids to their right. Depending on where these adjacent groups are judged to begin and end, there are at least five competing proposals for which elements to include: the three most common contain six, ten and thirteen elements, respectively (see image). All proposals include gallium, indium, tin, thallium, lead, and bismuth. Physically, post-transition metals are soft (or brittle), have poor mechanical strength, and have melting points lower than those of the transition metals. Being close to the metal-nonmetal border, their crystalline structures tend to show covalent or directional bonding effects, having generally greater complexity or fewer nearest neighbours than other metallic elements. Chemically, they are characterised—to varying degrees—by covalent bonding tendencies, acid-base amphoterism and the formation of anionic species such as aluminates, stannates, and bismuthates (in the case of aluminium, tin, and bismuth, respectively). They can also form Zintl phases (half-metallic compounds formed between highly electropositive metals and moderately electronegative metals or metalloids). The name is universally used, but not officially sanctioned by any organization such as the IUPAC. The origin of the term is unclear: one early use was in 1940 in a chemistry text. Alternate names for this group are B-subgroup metals, other metals, and p-block metals; and at least thirteen other labels.
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  • 21 Nov 2022
Topic Review
Backbone Chain
In polymer science, the backbone chain of a polymer is the longest series of covalently bonded atoms that together create the continuous chain of the molecule. This science is subdivided into the study of organic polymers, which consist of a carbon backbone, and inorganic polymers which have backbones containing only main group elements. In biochemistry, organic backbone chains make up the primary structure of macromolecules. The backbones of these biological macromolecules consist of central chains of covalently bonded atoms. The characteristics and order of the monomer residues in the backbone make a map for the complex structure of biological polymers (see Biomolecular structure). The backbone is, therefore, directly related to biological molecules’ function. The macromolecules within the body can be divided into four main subcategories, each of which are involved in very different and important biological processes: proteins, carbohydrates, lipids, and nucleic acids. Each of these molecules has a different backbone and consists of different monomers each with distinctive residues and functionalities. This is the driving factor of their different structures and functions in the body. Although lipids have a "backbone," they are not true biological polymers as their backbone is a three carbon molecule, glycerol, with longer substituent "side chains." For this reason, only proteins, carbohydrates, and nucleic acids should be considered as biological macromolecules with polymeric backbones.
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  • 21 Nov 2022
Topic Review
Salt and Cardiovascular Disease
Salt consumption has been extensively studied for its role in human physiology and impact on human health. Chronic, high intake of dietary salt consumption is associated with hypertension and cardiovascular disease, in addition to other adverse health outcomes. Major health and scientific organizations, such as the World Health Organization, US Centers for Disease Control and Prevention, and American Heart Association, have established high salt consumption as a major risk factor for cardiovascular diseases and stroke. Common edible salt is composed of sodium chloride.
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  • 21 Nov 2022
Topic Review
Herbicide Resistance Risk and Novel Potential Herbicide Targets
To date, effectively controlling resistant weeds has been a great challenge in modern agricultural production. Developing new modes of action of herbicides would be an efficient, convenient, and . In particular, new modes of herbicide action do not appear to have evolutionary resistance or cross-resistance with existing herbicides. However, a few successful herbicides with new modes of action (MoAs) have been marketed in the past 20 years. Researchers summarized the positive herbicide targets for the herbicides that have been discovered in recent years, such as Solanyl Diphosphate Synthase (SPS), Fatty Acid Thioesterase (FAT), Plastid Peptide Deformylase (PDEF), and Dihydroxy-Acid Dehydratase (DHAD). Some commercial herbicide varieties have been obtained based on novel herbicide targets, such as Homogentisate Solanesyltransferase (HST) and Dihydroorotate Dehydrogenase (DHODH). This provides a new reference and idea for herbicide molecular design in the future. 
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  • 21 Nov 2022
Topic Review
Synthesis of Thienothiophenes
Thienothiophenes (TT), formed by two annulated thiophene rings, represent fully the planar system, whose embedding into a molecular architecture can significantly improve/alter the fundamental properties of organic, π-conjugated materials. 
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  • 21 Nov 2022
Topic Review
Chemical Safety
Chemicals as elements, compounds, mixtures, solutions and emulsions are very widely used and transported in the modern industrial society. Of necessity, they are also used in schools, universities and other training facilities to educate pupils in their safe use and handling and also are commonly used in domestic situations for cleaning, gardening and DIY. However, there are chemicals that should not mix or get in contact with others, as they can produce byproducts that may be toxic, carcinogenic, explosive etc, or can be dangerous themselves. To avoid disasters and mishaps, maintaining safety is considered paramount, especially by chemists. Chemical safety includes all those policies, procedures and practices designed to minimise the risk of exposure to potentially hazardous chemicals. This includes the risks of exposure to persons handling the chemicals, to the surrounding environment, and to the communities and ecosystems within that environment. The hazardous nature of many chemicals may be increased when mixed with other chemicals, heated or handled inappropriately. In a chemically safe environment, users are able to take appropriate actions in case of accidents although many incidents of exposure to chemical hazards occur outside of a controlled environments such as manufacturing plants or laboratories. It is estimated that 1.6 million human deaths occur each year from contact with hazardous chemicals. and that in 2016, 45 million disability-adjusted life-years were lost, a significant increase from 2012.
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  • 21 Nov 2022
Topic Review
Antioxidant Compounds Extracted from Plants for Vegetable Oils
Oil oxidation is the main factor limiting vegetable oils’ quality during storage, as it leads to the deterioration of oil’s nutritional quality and gives rise to disagreeable flavors. These changes make fat-containing foods less acceptable to consumers. To deal with this problem and to meet consumer demand for natural foods, vegetable oil fabricators and the food industry are looking for alternatives to synthetic antioxidants to protect oils from oxidation. In this context, natural antioxidant compounds extracted from different parts (leaves, roots, flowers, and seeds) of medicinal and aromatic plants (MAPs) could be used as a promising and sustainable solution to protect consumers’ health. 
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  • 21 Nov 2022
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