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Topic Review
Near-Infrared Hyperspectral Imaging Techniques for Non-Destructive Quality Assessment
Hyperspectral imaging (HSI) is one of the most often used techniques for rapid quality evaluation for various applications. It is a non-destructive technique that effectively evaluates the quality attributes of root and tuber crops, including yam and cassava, and their food products. Hyperspectral imaging technology, which combines spectroscopy and imaging principles, has an advantage over conventional spectroscopy due to its ability to simultaneously evaluate the physical characteristics and chemical components of various food products and specify their spatial distributions. HSI has demonstrated significant potential for obtaining quick information regarding the chemical composition of the root and tuber, such as starch, protein, dry matter, amylose, and soluble sugars, as well as physical characteristics such as textural properties and water binding capacity.
  • 323
  • 25 Apr 2023
Topic Review
Quinoxaline-Based Photoinitiators of Polymerization
Photopolymerization offers a unique opportunity to convert liquid monomers to polymers using light as the activation source. Major efforts have been devoted to developing visible light photo-initiating systems, and the search for new dyes that can be incorporated into photocurable resins and polymerize a resin within a few seconds is still ongoing.
  • 569
  • 24 Apr 2023
Topic Review
MIP Application for the Detection of Cancer Biomarkers
Biomarkers can provide critical information about cancer and many other diseases; therefore, developing analytical systems for recognising biomarkers is an essential direction in bioanalytical chemistry. Molecularly imprinted polymers (MIPs) have been applied in analytical systems to determine biomarkers. The most attractive way to replace natural biological recognition systems is based on applying molecularly imprinted polymers.
  • 471
  • 24 Apr 2023
Topic Review
Synthetic Polymeric Corrosion Inhibitor
An anti-corrosion inhibitor is one of the most useful methods to prevent metal corrosion toward different media. In comparison with small molecular inhibitors, a polymeric inhibitor can integrate more adsorption groups and generate a synergetic effect, which has been widely used in industry and become a hot topic in academic research.
  • 447
  • 24 Apr 2023
Topic Review
Safe(r)-By-Design CuO Nanoparticles
Safe(r)-by-design modifications of CuO nanoparticles target the release of Cu ions and/or the generation of reactive oxygen species (ROS). Two strategies can be found in safe-by-design studies. One safe-by-design strategy regarding CuO nanoparticles is based on coating or capping (surface modification), often with organic substances. Another safe-by-design strategy for CuO nanoparticles is based on doping. 
  • 396
  • 24 Apr 2023
Topic Review
Adsorption Properties of Polysaccharide-Based Natural Polymer Hydrogels
The pollution and scarcity of freshwater resources are global problems that have a significant influence on human life. It is very important to remove harmful substances in the water to realize the recycling of water resources. Hydrogels have recently attracted attention due to their special three-dimensional network structure, large surface area, and pores, which show great potential for the removal of pollutants in water. In their preparation, natural polymers are one of the preferred materials because of their wide availability, low cost, and easy thermal degradation. However, when it is directly used for adsorption, its performance is unsatisfactory, so it usually needs to be modified in the preparation process. 
  • 498
  • 24 Apr 2023
Topic Review Peer Reviewed
Molecular Filters in Medicinal Chemistry
Efficient chemical library design for high-throughput virtual screening and drug design requires a pre-screening filter pipeline capable of labeling aggregators, pan-assay interference compounds (PAINS), and rapid elimination of swill (REOS); identifying or excluding covalent binders; flagging moieties with specific bio-evaluation data; and incorporating physicochemical and pharmacokinetic properties early in the design without compromising the diversity of chemical moieties present in the library. This adaptation of the chemical space results in greater enrichment of hit lists, identified compounds with greater potential for further optimization, and efficient use of computational time. A number of medicinal chemistry filters have been implemented in the Konstanz Information Miner (KNIME) software and analyzed their impact on testing representative libraries with chemoinformatic analysis. It was found that the analyzed filters can effectively tailor chemical libraries to a lead-like chemical space, identify protein–protein inhibitor-like compounds, prioritize oral bioavailability, identify drug-like compounds, and effectively label unwanted scaffolds or functional groups. However, one should be cautious in their application and carefully study the chemical space suitable for the target and general medicinal chemistry campaign, and review passed and labeled compounds before taking further in silico steps.
  • 653
  • 24 Apr 2023
Topic Review
Shellac and Its Potential in the Packaging Application
Shellac, an insect-derived material, has received the least attention due to its scarcity in south Asia. Currently, Shellac is used in various applications, such as furniture polish, glazing agent for candies and pharmaceutical pills, coating on fruits to increase shelf life, primers, smart sensor, 3D printing, and green electronic. However, the limitations of Shellac such as: brittleness with time, self-esterification, low transparency, solubility in alkaline medium and in most organic solvents have limited its usage in the packaging application. Many of these problems can be improved by physical blending or chemical reaction with other materials to make Shellac more durable, impede self-esterification, and facilitate the film-forming ability, which suggests the potential usage of Shellac in packaging applications.
  • 1.1K
  • 21 Apr 2023
Topic Review
The Challenging Treatment of Cisplatin-Resistant Tumors
Cancer is one of the most lethal diseases, causing millions of deaths worldwide. In particular, carcinogenesis, the process responsible for healthy cells’ transformation into tumoral cells, is characterized by multi-stage evolution: initiation, promotion, and the malignant transformation of cells and progression. During this process, some DNA mutations occur, providing the cancer with different distinctive features, such as uncontrolled cell proliferation, replicative cell immortality, the circumvention of growth suppressors, the induction of angiogenesis, resistance to cell death, activation to invasion, and metastasis. The principal cancer treatments rely on surgical resection, radiotherapy, chemotherapy, immunotherapy, and targeted therapy, but usually combined therapy is the preferred choice. Indeed, after surgery, the patient often undergoes radio- or chemotherapy. 
  • 359
  • 21 Apr 2023
Topic Review
Glass-Ceramic Solid-State Electrolytes for Lithium Batteries
The all-solid-state lithium battery (ASSLIB) is one of the key points of future lithium battery technology development. Because solid-state electrolytes (SSEs) have higher safety performance than liquid electrolytes, and they can promote the application of Li-metal anodes to endow batteries with higher energy density. Glass-ceramic SSEs with excellent ionic conductivity and mechanical strength are one of the main focuses of SSE research. 
  • 452
  • 21 Apr 2023
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