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Topic Review
Cellulose-Based Polymers in Additive Manufacturing
The materials for additive manufacturing (AM) technology have grown substantially over the last few years to fulfill industrial needs. Despite that, the use of bio-based composites for improved mechanical properties and biodegradation is still not fully explored. This limits the universal expansion of AM-fabricated products due to the incompatibility of the products made from petroleum-derived resources. The development of naturally-derived polymers for AM materials is promising with the increasing number of studies in recent years owing to their biodegradation and biocompatibility. Cellulose is the most abundant biopolymer that possesses many favorable properties to be incorporated into AM materials, which have been continuously focused on in recent years. This critical review discusses the development of AM technologies and materials, cellulose-based polymers, cellulose-based three-dimensional (3D) printing filaments, liquid deposition modeling of cellulose, and four-dimensional (4D) printing of cellulose-based materials. Cellulose-based AM material applications and the limitations with future developments are also reviewed.
  • 1.8K
  • 02 Sep 2020
Topic Review
Polyurethanes in Biomedicine
Due to their mechanical properties, ranging from flexible to hard materials, polyurethanes (PUs) have been widely used in many industrial and biomedical applications. PU characteristics, along with their biocompatibility, make them successful biomaterials in short and medium time applications.  The most important biomedical applications of PUs include antibacterial surfaces and catheters, blood oxygenators, dialysis devices, stents, cardiac valves, vascular prostheses, bioadhesives/surgical dressings/pressure sensitive adhesives, drug delivery systems, tissue engineering scaffolds and electrospinning, nerve generation, pacemaker lead insulation and coatings for breast implants. The diversity of polyurethane properties due to the ease of bulk and surface modification plays a vital role in their applications. 
  • 1.8K
  • 28 Oct 2020
Topic Review
Lignin-Based Resins
By increasing the environmental concerns and depletion of petroleum resources, bio-based resins have gained interest. Recently, lignin-based resins have attracted attention due to their low cost, environmental benefits, good thermal stability, excellent mechanical properties, and suitability for high-performance natural fiber composite applications. This content highlights the recent use of lignin-based resins with natural fiber composites for high-performance applications. 
  • 1.8K
  • 31 Dec 2021
Topic Review Peer Reviewed
Deep Eutectic Solvents and Pharmaceuticals
Deep eutectic solvents (DES) are eutectic mixtures that present a deviation from the ideal thermodynamic solid–liquid phase behavior, where a significant depression in the melting temperature occurs. If properly designed and chosen, DES may be liquid at room and the human body’s temperatures and display a biocompatible character, thus representing relevant options in the pharmaceutical field. Accordingly, DES have been studied as alternative solvents or in formulations of pharmaceuticals to improve their solubility and stability. Depending on the DES components, these mixtures might exhibit interesting biological activities compatible with several applications. The use of DES as functional agents or as novel liquid forms of active pharmaceutical ingredients (API-DES) with the goal of improving bioavailability, permeability and therapeutic efficacy of a given API stands as alternative strategies in the pharmaceutical field for drug delivery purposes.
  • 1.7K
  • 13 Apr 2022
Topic Review
Solvent-Free Synthesis of Zeolites
The traditional hydrothermal method to prepare zeolite will inevitably use a large amount of water as a solvent, which will lead to higher autogenous pressure, low efficiency, and wastewater pollution. The solvent-free method can be used to synthesize various types of zeolites by mechanical mixing, grinding, and heating of solid raw materials, which exhibits the apparent advantages of high yield, low pollution, and high efficiency. This review mainly introduces the development process of solvent-free synthesis, preparation of hierarchical zeolite, morphology control, synthesis mechanism and applications of solvent-free methods. It can be believed that solvent-free methods will become a research focus and have enormous industrial application potential.
  • 1.8K
  • 25 Mar 2021
Topic Review
Plant-Based Biosynthesis of Copper/Copper Nanoparticles
Plants produce numerous secondary metabolites and rich in phytochemicals, which are potential bioresources for synthesizing Cu and CuO Nanoparticles (NPs). This green synthesis approach is environmentally friendly and more advantageous over commercial synthesis using physical and chemical methods. The green synthesized Cu and CuO NPs can be used as anticancer, antibacterial, antifungal and anti-inflammatory agents in biomedical applications. We discuss about the green synthesis of Cu and CuO NPs using various plants, factors affecting the synthesis, biomedical applications, and toxicity evaluation of the NPs. In addition, the mechanisms of the NPs entry into biological entities were also discussed. 
  • 1.8K
  • 01 Jun 2021
Topic Review
Mixture Designs of Experiments
The experimental designs for mixtures are a subclass of experimental designs useful for studying the effects of ingredients/components in formulations. 
  • 1.8K
  • 04 Jun 2021
Topic Review
Polyetheretherketone
Polyetheretherketone (PEEK) is an aromatic, semi-crystalline linear thermoplastic polymer.
  • 1.8K
  • 18 Mar 2021
Topic Review
Potential Energy of Protein
In the context of chemistry and molecular modelling, a force field is a computational method that is used to estimate the forces between atoms within molecules and also between molecules. More precisely, the force field refers to the functional form and parameter sets used to calculate the potential energy of a system of atoms or coarse-grained particles in molecular mechanics, molecular dynamics, or Monte Carlo simulations. The parameters for a chosen energy function may be derived from experiments in physics and chemistry, calculations in quantum mechanics, or both. Force fields are interatomic potentials and utilize the same concept as force fields in classical physics, with the difference that the force field parameters in chemistry describe the energy landscape, from which the acting forces on every particle are derived as a gradient of the potential energy with respect to the particle coordinates. All-atom force fields provide parameters for every type of atom in a system, including hydrogen, while united-atom interatomic potentials treat the hydrogen and carbon atoms in methyl groups and methylene bridges as one interaction center. Coarse-grained potentials, which are often used in long-time simulations of macromolecules such as proteins, nucleic acids, and multi-component complexes, sacrifice chemical details for higher computing efficiency.
  • 1.8K
  • 23 Nov 2022
Topic Review
Proteomics for Studying Antibiotic Action
To design more efficient treatments against bacterial infections, detailed knowledge about the bacterial response to the commonly used antibiotics is required. Proteomics is a well-suited and powerful tool to study molecular response to antimicrobial compounds. Bacterial response profiling from system-level investigations could increase our understanding of bacterial adaptation, the mechanisms behind antibiotic resistance and tolerance development.
  • 1.8K
  • 03 Nov 2020
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