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Topic Review
Thermal Stability of Layered LTMO2
Layered lithium transition metal (TM) oxides LiTMO2 (TM = Ni, Co, Mn, Al, etc.) are the most promising cathode materials for lithium-ion batteries because of their high energy density, good rate capability and moderate cost. However, the safety issue arising from the intrinsic thermal instability of nickel-based cathode materials is still a critical challenge for further applications in electric vehicles and energy storage power stations.
  • 587
  • 15 Mar 2023
Topic Review
Calcium-Dependent Protein Kinases
Calcium-dependent protein kinases (CDPKs) comprise a unique family of serine/threonine kinases only found in plants, protozoans (including apicomplexan parasites) and some algae. As these enzymes play an important role in calcium signalling during the various life stages of the Plasmodium parasite, CDPKs have been identified as potential targets for next-generation antimalarial drug development.  This entry focusses on the different CDPKs identified for Plasmodium falciparum, their possible functions, and the small-molecule inhibitors developed thus far for this group of kinases.
  • 586
  • 27 Dec 2020
Topic Review
Red Alga Dixoniella grisea
There is an increasing interest in algae-based raw materials for medical, cosmetic or nutraceutical applications. Additionally, the high diversity of physicochemical properties of the different algal metabolites proposes these substances from microalgae as possible additives in the chemical industry. Among the wide range of natural products from red microalgae, research has mainly focused on extracellular polymers for additive use, while this study also considers the cellular components. 
  • 586
  • 25 Oct 2021
Topic Review
Application of Nanomaterial Modified Aptamer-Based Electrochemical Sensor
The electrochemical aptamer sensor (E-apt sensor), which is composed of biometric elements and signal sensors, has attracted more and more attention for this purpose. The signal sensor usually consists of an electrode substrate, modified layer, and electrochemical signal detection system. The most widely used electrode substrates include a gold electrode (AuE), glassy carbon electrode (GCE), indium tin oxide electrode (ITO), reduced graphene electrode (ERGO), and screen-printed electrode (SPE). Nanomaterials are particularly important in the construction of E-apt sensors, which can be used as aptamer carriers or sensitizers to stimulate or inhibit electrochemical signals.
  • 586
  • 31 May 2022
Topic Review
Application of Additional Conductive Layers
Polymer composites are at increasingly used as structural materials replacing metal alloys due to their high strength-to-weight ratio and corrosion resistance. The conductivity of epoxy resin, depending on its type, ranges from 10−17 to 10−12 S/cm, so it is classified as an insulator, i.e., a material with a conductivity below 10−12 S/cm, while carbon fiber is about 6 × 102 S/cm, which allows it to be classified as a semiconductor, i.e., a material whose conductivity is between 10−12 and 103 S/cm. The EP/CF composite, on the other hand, has a conductivity of about 10−4–10−2 S/cm, that is, it also classifies as a semiconductor. The methods to improve the conductivity have been categorized into three groups: modification of the matrix with conductive fillers, modification of the composite reinforcement, and addition of layers with increased electrical conductivity to the composite. 
  • 586
  • 19 Jul 2022
Topic Review
Polymeric Nanocomposite Membranes for Water Purification and Scalability
Water shortage is a major worldwide issue. Filtration using genuine polymeric membranes demonstrates excellent pollutant separation capabilities; however, polymeric membranes have restricted uses. Nanocomposite membranes, which are produced by integrating nanofillers into polymeric membrane matrices, may increase filtration. Carbon-based nanoparticles and metal/metal oxide nanoparticles have received the greatest attention.
  • 586
  • 15 Nov 2022
Topic Review
Cannabis sativa Bioactive Compounds in Colorectal Cancer
Cannabis sativa is a multipurpose plant that has been used in medicine for centuries. Considerable research has focused on the bioactive compounds of this plant, particularly cannabinoids and terpenes. Among other properties, these compounds exhibit antitumor effects in several cancer types, including colorectal cancer (CRC). Cannabinoids show positive effects in the treatment of CRC by inducing apoptosis, proliferation, metastasis, inflammation, angiogenesis, oxidative stress, and autophagy. Terpenes, such as β-caryophyllene, limonene, and myrcene, have also been reported to have potential antitumor effects on CRC through the induction of apoptosis, the inhibition of cell proliferation, and angiogenesis. In addition, synergy effects between cannabinoids and terpenes are believed to be important factors in the treatment of CRC. 
  • 586
  • 18 May 2023
Topic Review
Potentiometry and Ion-Selective Electrodes
Potentiometry is a highly selective and relatively cheap method that allows achieving low detection limits and a very wide dynamic range of sensors (up to eight orders of units). The principle of the method is to measure the electromotive force (EMF) of a cell made of two types of electrodes: a reference electrode whose potential has to necessarily be constant regardless of the composition and concentration of the sample, and an indicator (working) electrode whose potential changes depending on the activity of the main ion present in the sample solution to which the ion-selective membrane is sensitive.
  • 586
  • 04 Jul 2023
Topic Review
Solar Photooxygenations for Chemical Manufacturing
Photooxygenation reactions involving singlet oxygen (1O2) are utilized industrially as a mild and sustainable access to oxygenated products. Due to the usage of organic dyes as photosensitizers, these transformations can be successfully conducted using natural sunlight. Modern solar chemical reactors enable outdoor operations on the demonstration (multigram) to technical (multikilogram) scales and have subsequently been employed for the manufacturing of fine chemicals such as fragrances or biologically active compounds. This review highlights examples of solarphotooxygenations for the manufacturing of industrially relevant target compounds and discusses current challenges and opportunities of this sustainable methodology.
  • 585
  • 29 Mar 2021
Topic Review
Engineering Crystal Packing in RNA
The crystal packing strategies described in this entry can reduce the flexibility of the interacting regions. Some of these crystal packing modules generate symmetry, which should promote crystallization because proteins with molecular symmetry are known to crystallize more readily than those without molecular symmetry. For example, the kissing loop complex generates two-fold symmetry, the G-quadruplex generates a four-fold symmetry, and the 3WJ junction has been further engineered to form a stable planar triangle, square, and pentagon using oligonucleotides.
  • 585
  • 07 Sep 2021
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