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Topic Review
Willardiine and Its Analogues
Willardiine was first identified by Rolf Gimelin in 1959 from the extracts of seeds of Acacia willardiana. Structurally it corresponds to (2S)-2-amino-3-(2,4-dioxopyrimidin-1-yl)propanoic acid (1) and carrying an uracil moiety it can be ascribed to the category of nucleoamino acids. Willardiine is synthesized by the single specific enzyme uracilylalanine synthase, and the N–heterocyclic moiety uracil obtained by the orotate pathway proved to be an effective bioisostere for the distal carboxyl group of L-glutamate. Different  aspects on both chemistry and biotechnological applications of willardine/willardine-analogues and nucleopeptides will be reviewed herein.
  • 611
  • 18 Oct 2022
Topic Review
Surface Plasmon Coupled Emission Technology
Novel nano-engineering protocols have been actively synergized with fluorescence spectroscopic techniques to yield higher intensity from radiating dipoles, through the process termed plasmon-enhanced fluorescence (PEF). Consequently, the limit of detection of analytes of interest has been dramatically improvised on account of higher sensitivity rendered by augmented fluorescence signals. Metallic thin films sustaining surface plasmon polaritons (SPPs) have been creatively hybridized with such PEF platforms to realize a substantial upsurge in the global collection efficiency in a judicious technology termed surface plasmon-coupled emission (SPCE). This Editorial Review by Dr. Seemesh Bhaskar, University of Illinois Urbana-Champaign, provides a spotlight on the latest developments in SPCE substrate engineering to the broad audience of photo-plasmonics, spectroscopy, micro- & nanotechnology, life sciences, thin films and point-of-care diagnostics.
  • 611
  • 13 Mar 2023
Topic Review
Applications of Metallic Glasses
Metallic glasses can be a perfect alternative to conventional crystalline biomaterials (such as 316L stainless steel, Ti or Ti-based alloys, Zr or Zr-based alloys, Co-Cr alloys, etc.) when used as coatings for surgical devices and implants inside the human body. Owing to their outstanding electrocatalytic activity and durability, metallic glasses can be considered prominent candidates for energy-storage and -conversion devices, such as fuel and electrolysis cells, and batteries. Metallic-glass systems are gaining substantial momentum in the micro- and nano-imprinting of optoelectronic devices.
  • 611
  • 19 Dec 2023
Topic Review
Flexible Pressure Sensor Arrays
Flexible pressure sensors that can maintain their pressure sensing ability with arbitrary deformation play an essential role in a wide range of applications, such as aerospace, prosthetics, robotics, healthcare, human–machine interfaces, and electronic skin. Flexible pressure sensor arrays can visualize touch actions, track motion trajectories, and map pressure distribution in real time with high pressure sensitivity and high resolution.
  • 610
  • 05 Aug 2022
Topic Review
Copper-Based Metal–Organic Frameworks for Click Chemistry
In the extensive terrain of catalytic procedures for the synthesis of organic molecules, metal–organic frameworks (MOFs) as heterogenous catalysts have been investigated in a variety of chemical processes, including Friedel–Crafts reactions, condensation reactions, oxidations, and coupling reactions, and utilized owing to their specific properties such as high porosity, tuneability, extraordinary catalytic activity, and recyclability.
  • 610
  • 13 Jan 2023
Topic Review
Carbon Dots in Biotechnology and Food Technology
Materials with a “nano” structure are increasingly used in medicine and biotechnology as drug delivery systems, bioimaging agents or biosensors in the monitoring of toxic substances, heavy metals and environmental variations. Furthermore, in the food industry, they have found applications as detectors of food adulteration, microbial contamination and even in packaging for monitoring product freshness. Carbon dots (CDs) as materials with broad as well as unprecedented possibilities could revolutionize the economy, if only their synthesis was based on low-cost natural sources. 
  • 610
  • 13 Oct 2023
Topic Review
Translating Nanobiotechnology in Medical Theranostics
Nanotheranostic is a word we use a bit more than a decade ago to define namaterials with potential or confirmed use as therapeutic and/or diagnostic agents.  Here, we strived to define the properties characteristics and of most commonly used nanomaterials that have been proved or could be apply for a wide range of biomedical and pharmaceutical applications (e.g. biosensing, drug delivery, imaging).
  • 609
  • 25 Nov 2020
Topic Review
Polyethyleneimine-Based Lipopolyplexes
Lipopolyplexes based on poliethylenimine are an interesting platform for future anti-cancer gene therapies. The carrier consists of nucleic acids condensed with poliethylenimine chains and enclosed in lipid vesicles. Lipopolyplexes could be very versatile, what enables tailoring the carrier for specific thereapeutic needs, however the preparation process is a multistage and fairly sensitive one, which additionally requires a specific balance to be maintained between its stability in the body, which would allow the appropriate dose of the preparation to reach the target site, and the ability to release nucleic acid at the right place and time.
  • 609
  • 10 Jan 2022
Topic Review
Advantages on Waste Management in Hydrogen Industry
The turn to hydrogen as an energy source is a fundamentally important task facing the global energetics, aviation and automotive industries. This step would reduce the negative man-made impact on the environment on the one hand, and provide previously inaccessible power modes and increased resources for technical systems, predetermining the development of an absolutely new life cycle for important areas of technology, on the other. The most important aspect in this case is the development of next-generation technologies for hydrogen industry waste management that will definitely reduce the negative impact of technology on the environment. 
  • 609
  • 23 Nov 2022
Topic Review
Application of Polysaccharides in Biodegradable Films
Biodegradable films emerge as alternative biomaterials to conventional packaging from fossil sources, which, in addition to offering protection and increasing the shelf life of food products, are ecologically sustainable. The materials mostly used in their formulation are based on natural polysaccharides, plasticizing agents, and bioactive components (e.g., antimicrobial agents or antioxidants). The formulation of biodegradable films from polysaccharides and various plasticizers represents an alternative for primary packaging that can be assigned to specific food products, which opens the possibility of having multiple options of biodegradable films for the same product.
  • 608
  • 08 Jul 2022
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