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Topic Review
Neurofibroma Development in Neurofibromatosis Type 1
Neurofibromatosis type 1 (NF1), a genetic tumor predisposition syndrome that affects about 1 in 3000 newborns, is caused by mutations in the NF1 gene and subsequent inactivation of its encoded neurofibromin. Neurofibromin is a tumor suppressor protein involved in the downregulation of Ras signaling. Despite a diverse clinical spectrum, one of several hallmarks of NF1 is a peripheral nerve sheath tumor (PNST), which comprises mixed nervous and fibrous components. The distinct spatiotemporal characteristics of plexiform and cutaneous neurofibromas have prompted hypotheses about the origin and developmental features of these tumors, involving various cellular transition processes. 
  • 408
  • 26 Sep 2022
Topic Review
Protection of Patient Data in Digital Oral
The use of digital health technologies, including telemedicine and teledentistry, has become a necessity in healthcare due to the SARS-CoV-19 pandemic. These technologies allow for the reduction of the workload of healthcare providers and the improvement of patient outcomes in cases of remote monitoring, diagnosis, and communication. While there are no doubtful benefits, there are some counterparts, such as concerns about clinical risks, data security, and privacy protection. 
  • 408
  • 13 Apr 2023
Topic Review
Media Influencing Public Intentions for Influenza Vaccination
Influenza has become a global public health issue. As an effective means of prevention and treatment, it is desired to improve public acceptance of influenza vaccination. Researchers have found a correlation between media communications and influenza vaccination. They believed that media information impacts public awareness of influenza prevention, further affecting influenza vaccination. However, few studies specifically discuss the influence mechanism of media communication, public awareness of the influenza vaccine, and influenza vaccination. Furthermore, research on media communication and influenza vaccination has rarely focused on China. 
  • 408
  • 07 Apr 2022
Topic Review
Resistance Training: Intensity and Volume
Resistance training is a form of exercise that can increase or maintain muscle mass and muscle strength, which helps older adults preserve their independence and quality of life. It can overcome the loss of muscle mass and strength, build resilience, ease the management of chronic conditions, and reduce physical vulnerability. Resistance training can be done in several ways depending on the physiological and functional or performance goals. The different trainable characteristics of the neuromuscular system include strength, endurance, power, muscle hypertrophy, and motor performance. A list of resistance training types for practical resistance training in older adults is presented below, pointing out intensity and volume.
  • 407
  • 25 Feb 2022
Topic Review
Nanotechnologies in Obstetrics and Cancer during Pregnancy
Nanotechnology, the art of engineering structures on a molecular level, offers the opportunity to implement new strategies for the diagnosis and management of pregnancy-related disorders. Although nanotechnology has been on the bench for many years, most of the studies in obstetrics are preclinical. Ongoing research spans from the development of diagnostic tools, including optimized strategies to selectively confine contrast agents in the maternal bloodstream and approaches to improve diagnostics tests to be used in obstetrics, to the synthesis of innovative delivery nanosystems for therapeutic interventions. Using nanotechnology to achieve spatial and temporal control over the delivery of therapeutic agents (e.g., commonly used drugs, more recently defined formulations, or gene therapy-based approaches) offers significant advantages, including the possibility to target specific cells/tissues of interest (e.g., the maternal bloodstream, uterus wall, or fetal compartment). This characteristic of nanotechnology-driven therapy reduces side effects and the amount of therapeutic agent used. However, nanotoxicology appears to be a significant obstacle to adopting these technologies in clinical therapeutic praxis. 
  • 407
  • 30 Oct 2022
Topic Review
Impact of Premenstrual Syndrome on Quality of Life
Most women who menstruate experience various physical, psychological, and behavioral changes during the period between ovulation and menstruation. 
  • 407
  • 29 Jan 2024
Topic Review
Plant-Derived Nanoparticles in Food-Producing Animals
Antibiotics are regularly used in animal husbandry to treat diseases. This practice is beneficial to animals’ health and helps ensure food security. However, the misuse of antibiotics, especially in food-producing animals, has resulted in the advent of antimicrobial resistance (AMR) and its dissemination among foodborne pathogens. The occurrence of AMR in bacteria pathogens that cause infections in animals and those associated with food spoilage is now considered a global health concern affecting humans, animals and the environment. The search for alternative antimicrobial agents has kindled the interest of many researchers. Among the alternatives, using plant-derived nanoparticles (PDNPs) for treating microbial dysfunctions in food-producing animals has gained significant attention. In traditional medicine, plant extracts are considered as safe, efficient and natural antibacterial agents for various animal diseases. Given the complexity of the AMR and concerns about issues at the interface of human health, animal health and the environment, it is important to emphasize the role of a One Health approach in addressing this problem.
  • 407
  • 24 Oct 2022
Topic Review
Trends in Pollutant Accumulations in Energy-Efficient Residential Buildings
Improving the energy efficiency of buildings is a major target in developed countries toward decreasing their energy consumption and CO2 emissions. To meet this target, a large number of countries have established energy codes that require buildings to be airtight. While such a retrofitting approach has improved health outcomes in areas with heavy traffic, it has worsened the health outcomes in Nordic countries and increased the risk of lung cancer in areas with high levels of radon emissions. The implementation of mechanical ventilation in new energy-efficient buildings has solved some of these problems; however, for others, a decrease in the level of outdoor pollutants was still required in order to achieve a good indoor air quality. A good balance between the air exchange rate and the air humidity level (adapted to the location) is key to ensuring that exposure to the various pollutants that accumulate inside energy-efficient buildings is low enough to avoid affecting inhabitants′ health. Evidence of the protective effect of mechanical ventilation should be sought in dwellings where natural ventilation allows pollutants to accumulate to threatening levels. 
  • 406
  • 25 Mar 2022
Topic Review
Monkeypox in Occupational Settings
With ongoing climate change, which alters the conditions for pathogens and vectors, zoonotic diseases such as monkeypox virus will become a challenge and a great threat impacting global health in future decades. A current outbreak of monkeypox is occurring in over 125 countries, with a report of thousands of cases in countries where this virus has never appeared. Occupational exposure to the monkeypox virus has been identified as an issue of major concern for occupational health, especially in healthcare settings. A research following the PRISMA guidelines was performed, which analyzed the effects that the current monkeypox outbreak has in workplaces, given the potential exposure of healthcare workers to the virus, the possible spread of the virus in occupational settings, and the preventive measures that are necessary to implement. At the end of the selection process, 21 studies were included in the research. Healthcare workers are considered at a high risk, and similar preventive measures to those adopted during the SARS-CoV-2 pandemic must be implemented in all healthcare settings. The main recommendations for preventing and managing monkeypox in occupational settings are the vaccination of exposed workers, the prompt identification and isolation of infected individuals, and good hygiene practices. Education and specific training are necessary in non-endemic countries to make healthcare workers able to recognize the disease and prevent further contagions. Although monkeypox seems unlikely to reach the pandemic spread of COVID-19, an approach to global health even to avoid future zoonotic epidemics is required by all stakeholders. 
  • 406
  • 07 Nov 2022
Topic Review
Mechanisms, Techniques and Devices of Airborne Virus Detection
Airborne viruses, such as COVID-19, cause pandemics all over the world. Virus-containing particles produced by infected individuals are suspended in the air for extended periods, actually resulting in viral aerosols and the spread of infectious diseases. Aerosol collection and detection devices are essential for limiting the spread of airborne virus diseases. 
  • 406
  • 25 Apr 2023
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