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Topic Review
Biography
Topic Review
Unsilencing the Echoes of Historical Trauma
Indigenous communities in North America have distinct colonial histories with their own story of how their ancestors were able to survive the mass effort to take their land, resources, language, culture, and sometimes even their lives. These stories have been passed down orally and through the DNA of the descendants of survivors via epigenetics. The Historical Loss Scale (HLS) and Historical Loss Associated Symptoms Scale (HLASS) are two validated scales that measure historical trauma among Native Americans.
298
05 Jun 2023
Topic Review
Mitigation of Cadmium Toxicity
Cadmium (Cd) is an environmental toxicant of public health significance worldwide. Diet is the main Cd exposure source in the non-occupationally exposed and non-smoking populations. Metal transporters for iron (Fe), zinc (Zn), calcium (Ca), and manganese (Mn) are involved in the assimilation and distribution of Cd to cells throughout the body. Due to an extremely slow elimination rate, most Cd is retained by cells, where it exerts toxicity through its interaction with sulfur-containing ligands, notably the thiol (-SH) functional group of cysteine, glutathione, and many Zn-dependent enzymes and transcription factors. The simultaneous induction of heme oxygenase-1 and the metal-binding protein metallothionein by Cd adversely affected the cellular redox state and caused the dysregulation of Fe, Zn, and copper. Experimental data indicate that Cd causes mitochondrial dysfunction via disrupting the metal homeostasis of this organelle.
298
23 Sep 2022
Topic Review
Ele-Monitoring Systems and Ontology-Based Models in Asthma Domain
Asthma is a chronic respiratory disease characterized by severe inflammation of the bronchial mucosa. Allergic asthma is the most common form of this health issue. Asthma is classified into allergic and non-allergic asthma, and it can be triggered by several factors such as indoor and outdoor allergens, air pollution, weather conditions, tobacco smoke, and food allergens, as well as other factors. Asthma symptoms differ in their frequency and severity since each patient reacts differently to these triggers.
298
24 Jun 2022
Topic Review
Types of Breast Cancer Imaging
Cancer is an incurable disease based on unregulated cell division. Breast cancer is the most prevalent cancer in women worldwide, and early detection can lower death rates. Medical images can be used to find important information for locating and diagnosing breast cancer. The best information for identifying and diagnosing breast cancer comes from medical pictures.
299
09 Aug 2023
Topic Review
How Immune Responses Are Regulated
Most basic studies directed at how immune responses are regulated employ chemically “simple antigens”, usually purified proteins. The target antigens in many clinical situations, such as in autoimmunity, infectious diseases and cancer, are chemically “complex”, consisting of several distinct molecules, and they often are part of a replicating entity.
298
19 Mar 2024
Topic Review
Relationship between Personality and Intelligence
There are two major theories in this area. First, compensation theory suggests that conscientiousness acts as a “coping/reimbursing strategy” for less intelligent, but ambitious and competitive, people in particular settings. Thus, relatively less intelligent individuals may become more methodical, organised, thorough, and persistent (i.e., conscientious) to compensate for their relative lack of intelligence in a highly competitive educational or work environment. That is, they can achieve as much as bright people by simply working harder and smarter. Alternatively, relatively more intelligent people may tend to succeed based on their cognitive efficiency, rather than strenuous effort or persistent effort and organisation.
298
01 Jun 2023
Topic Review
Gender Differences in the Diagnosis of Dyslipidemia
Evidence shows that objectives for detecting and controlling dyslipidemia are not being effectively met, and outcomes differ between men and women.
297
10 Dec 2021
Topic Review
Universal Privacy Model for Electronic Health Record Systems
High-profile data breaches in systems such as Australia’s My Health Record (MHR) and the UK’s National Health Service (NHS) have exposed millions of records, resulting in substantial financial losses for the healthcare industry.
296
21 Jul 2023
Topic Review
Human Behavior in Plasmodium knowlesi Malaria Infection
P. knowlesi is a zoonotic disease transmitted by the Anopheles mosquito, which harbors the Plasmodium parasite. Previously, the disease was believed to occur only among the Macaca fascicularis and M. nemestrina monkeys, found largely in southeast Asia.
296
02 Apr 2022
Topic Review
Effects of High-Altitude Mountaineering on Mountaineers
Nowadays, with the convenience of international traveling and driven by many individuals’ fond dreams of challenging high-altitude exercises, high-altitude mountaineering is becoming increasingly popular worldwide. Therefore, researchers performed a meta-analysis to determine the effects of high-altitude mountaineering on cognitive functions in mountaineers before and after climbing.
296
04 May 2023
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