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All Topic Review Biography
Topic Review
Self-Directed Online Learning and Mental Health during COVID-19
During COVID-19, self-directed learning, contrasted with standardized learning, became a necessary and promoted learning method in public schools—one potentially supportive of mental health regularly in public schools through the use of online learning. This is important because negative mental health has been classified as a global crisis, with the highest and lowest student achievers recognized as at greatest risk. 
  • 415
  • 29 Aug 2023
Topic Review
Students’ Negative Emotional Symptoms during COVID-19
The impact of the coronavirus pandemic on negative emotional symptoms has been serious with studies reporting high prevalence rates for these. Isolation, reduced social contact, duration of quarantine and restrictions, which are the characteristics of a lockdown, played an important role in increased negative emotional symptoms for students.
  • 414
  • 04 Jan 2022
Topic Review
Endometrial Receptivity Array
Successful outcomes of in vitro fertilization (IVF) rely on both the formation of a chromosomally normal embryo and its implantation in a receptive endometrium. Pre-implantation genetic testing for aneuploidy (PGT-A) has been widely accepted as a tool to assess the viability of an embryo. In 2011, the endometrial receptivity array (ERA) was first published as a tool to determine when the endometrium is most receptive to an embryo, commonly referred to as the “window of implantation” (WOI). The ERA uses molecular arrays to assess proliferation and differentiation in the endometrium and screens for inflammatory markers. Unlike PGT-A, there has been dissent within the field concerning the efficacy of the ERA. 
  • 414
  • 05 May 2023
Topic Review
Cancer Stem Cells in Anti-Cancer Therapy
Cancer stem cells (CSCs) have been identified and characterized in both hematopoietic and solid tumors. Many studies showed that CSCs can be identified and isolated by their expression of specific cell markers, such as ALDH, Nanog, Sox2, OCT3/4. The significance of CSCs with respect to tumor biology and anti-cancer treatment lies in their ability to maintain quiescence with very slow proliferation, indefinite self-renewal, differentiation, and trans-differentiation such as epithelial–mesenchymal transition (EMT) and its reverse process mesenchymal–epithelial transition (MET). The ability for detachment, migration, extra- and intravasation, invasion and thereby of completing all necessary steps of the metastatic cascade highlights their significance for metastasis. In addition, CSCs comprise the cancer cell populations responsible for tumor growth and cancer metastasis, resistance to anticancer therapies.
  • 414
  • 17 May 2023
Topic Review
Health Information Systems for Healthcare
Health information system deployment has been driven by the transformation and digitalization confronting healthcare. The need and potential of these systems within healthcare have been tremendously driven by the global instability that has affected several interrelated sectors. Accordingly, many research studies have reported on the inadequacies of these systems within the healthcare arena, which have distorted their potential and offerings to revolutionize healthcare.
  • 414
  • 11 Apr 2023
Topic Review
Cervical Cancer Screening
In Southeast Asia, cervical cancer is the second most common cancer in women. Low coverage for cervical cancer screening (CCS) becomes a roadblock to disease detection and treatment. Herein, we identified the barriers to and facilitators of cervical cancer screening among women living in SEA.
  • 413
  • 17 May 2021
Topic Review
HIA in Public Health Genomics
Public health genomics (PHG) is the area of public health ensuring that scientific advances in genomics (“from cell...”) triggered by innovative technologies are timely, effectively and responsibly translated into health policies and practice for the benefit of population health (“...to society”). Health impact assessment (HIA) is a combination of procedures, methods and tools by which a policy, program or project may be judged as to its potential effects on the health of a population, and the distribution of those effects within the population. 
  • 413
  • 09 Feb 2021
Topic Review
COVID-19 and Gestational Diabetes
Gestational diabetes mellitus (GDM) is defined as glucose intolerance first identified during pregnancy and usually resolving after birth. Since the beginning of the COVID-19 pandemic, there has been a growing interest in the association between GDM and COVID-19.
  • 413
  • 13 Sep 2022
Topic Review
Post-COVID-19 Condition
COVID-19 is currently considered a systemic infection involving multiple systems and causing chronic complications. Compared to other post-viral fatigue syndromes, these complications are wider and more intense. The most frequent symptoms are profound fatigue, dyspnea, sleep difficulties, anxiety or depression, reduced lung capacity, memory/cognitive impairment, and hyposmia/anosmia. Risk factors for this condition are severity of illness, more than five symptoms in the first week of the disease, female sex, older age, the presence of comorbidities, and a weak anti-SARS-CoV-2 antibody response. Different lines of research have attempted to explain these protracted symptoms; chronic persistent inflammation, autonomic nervous system disruption, hypometabolism, and autoimmunity may play a role. Due to thyroid high ACE expression, the key molecular complex SARS-CoV-2 uses to infect the host cells, thyroid may be a target for the coronavirus infection. Thyroid dysfunction after SARS-CoV-2 infection may be a combination of numerous mechanisms, and its role in long-COVID manifestations is not yet established. The presence of post-COVID symptoms deserves recognition of COVID-19 as a cause of post-viral fatigue syndrome. It is important to recognize the affected individuals at an early stage so researchers can offer them the most adequate treatments, helping them thrive through the uncertainty of their condition.
  • 413
  • 20 Apr 2022
Topic Review
Fetal Alcohol Spectrum Disorders and Inadequacy of Care
Prenatal alcohol exposure is one of the major avoidable causes of developmental disruption and health abnormalities in children. Fetal alcohol spectrum disorders (FASDs), a significant consequence of prenatal alcohol exposure, have gained more attention. Fetal alcohol spectrum disorders are an umbrella term used to describe a pattern of disabilities and abnormalities that result from fetal exposure to ethanol during pregnancy and are the most common non-heritable causes of intellectual disability. The effects on the fetus may include physical, mental, behavioral, and/or learning disabilities, with possible lifelong implications, and encompass a phenotypic range that can greatly vary between individuals but reliably include one or more of the following: facial dysmorphism, fetal growth deficiency, central nervous system dysfunction, and neurobehavioral impairment. 
  • 412
  • 03 Jan 2024
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