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Topic Review
Arisaema Jacquemontii Blume
Arisaema jacquemontii Blume (Araceae) is a medicinally important plant and is used for the treatment of different diseases specially in dermatological disorders. Alkaloids, phenols, terpenes, flavonoids, glycosides, tannins have been reported from this plant. Antioxidant, antifungal, antibacterial and anticancer activities are also shown by Arisaema jacquemontii. 
  • 755
  • 15 Aug 2022
Topic Review
Carica papaya Leaf Juice for Dengue
Dengue, an Aedes mosquito-borne viral infection, has become a public health risk that demands the world’s focus, especially in tropical countries. Despite of the life-threatening complication, there are still no specific antiviral medications for dengue infection. This situation highlight the research need in identifying potent compounds with promising anti-dengue activities. Therefore, a scoping review was conducted to gather and highlight the available scientific evidence for the use of C. papaya leaf, particularly using juice form, as a complementary method in treating dengue infection.
  • 672
  • 21 Apr 2022
Topic Review
Datura Species
Datura, a genus of medicinal herb from the Solanaceae family, is credited with toxic as well as medicinal properties. The different plant parts of Datura sp., mainly D. stramonium L., commonly known as Datura or Jimson Weed, exhibit potent analgesic, antiviral, anti-diarrheal, and anti-inflammatory activities, owing to the wide range of bioactive constituents. With these pharmacological activities, D. stramonium is potentially used to treat numerous human diseases, including ulcers, inflammation, wounds, rheumatism, gout, bruises and swellings, sciatica, fever, toothache, asthma, and bronchitis. The primary phytochemicals investigation on plant extract of Datura showed alkaloids, carbohydrates, cardiac glycosides, tannins, flavonoids, amino acids, and phenolic compounds. It also contains toxic tropane alkaloids, including atropine, scopolamine, and hyoscamine. Although some studies on D. stramonium have reported potential pharmacological effects, information about the toxicity remains almost uncertain. Moreover, the frequent abuse of D. stramonium for recreational purposes has led to toxic syndromes. Therefore, it becomes necessary to be aware of the toxic aspects and the potential risks accompanying its use.
  • 1.5K
  • 25 Apr 2022
Topic Review
Glycyrrhiza glabra (Licorice)-Containing Herbs in Cancer Treatment
Cancer is one of the leading causes of premature death and a significant barrier to increasing life expectancy in almost every country in the world. Licorice belongs to the genus Glycyrrhiza, and radix glycyrrhizae (RG) is the dried roots and rhizomes of licorice. Licorice, as well as licorice-purified compounds, has the potential to abrogate the onset and progression of different malignancy cancers, both in vitro and in vivo. Moreover, previous studies also suggest that licorice is a beneficial medicine plant used as a cure for nausea and vomiting.
  • 392
  • 14 Jul 2022
Topic Review
Açaí (Euterpe oleracea Mart.) in Health and Disease
The açaí palm (Euterpe oleracea Mart.), a species belonging to the Arecaceae family, has been cultivated for thousands of years in tropical Central and South America as a multipurpose dietary plant. The recent introduction of açaí fruit and its nutritional and healing qualities to regions outside its origin has rapidly expanded global demand for açaí berry. The health-promoting and disease-preventing properties of this plant are attributed to numerous bioactive phenolic compounds present in the leaf, pulp, fruit, skin, and seeds. It showed that açaí possesses antioxidant and anti-inflammatory properties and exerts cardioprotective, gastroprotective, hepatoprotective, neuroprotective, renoprotective, antilipidemic, antidiabetic, and antineoplastic activities. Moreover, clinical trials have suggested that açaí can protect against metabolic stress induced by oxidation, inflammation, vascular abnormalities, and physical exertion. 
  • 416
  • 22 Feb 2023
Topic Review
Acupuncture Regulating Neuro-Endocrine-Immune Network System
Acupuncture can regulate the release of neurotransmitters, neuropeptides and hormones by stimulating the neuroendocrine system. In addition, acupuncture can also indirectly affect the immune system by regulating the neuroendocrine system, specifically embodying the substances released by the neuroendocrine system acting on the corresponding receptors of immune organs and immune cells. As benign stress, acupuncture can change the concentration of certain neurotransmitters, including monoamines and acetylcholine. As the main neurotransmitters of sympathetic nerves, the concentration of monoamine neurotransmitters in the blood can be significantly increased by sympathetic neurostimulation, thus affecting the immune system.  
  • 523
  • 08 Sep 2021
Topic Review
Aging Disrupts Circadian Rhythms in Mouse Liver Mitochondria
The circadian clock regulates daily changes in behavioral, endocrine, and metabolic activities in mammals. Circadian rhythms in cellular physiology are significantly affected by aging. Aging induces changes in gene expression levels and rhythms in peripheral and probably central tissues.
  • 195
  • 16 Jun 2023
Topic Review
Anti-Diabetic Mechanisms of Glycyrrhizic acid and Its Derivatives
Type 2 diabetes mellitus (T2DM) is a chronic metabolic disease, which is characterized by hyperglycemia, chronic insulin resistance, progressive decline in β-cell function, and defect in insulin secretion. It has become one of the leading causes of death worldwide. There is no cure for T2DM, but it can be treated, and blood glucose levels can be controlled. It has been reported that diabetic patients may suffer from the adverse effects of conventional medicine. Therefore, alternative therapy, such as traditional Chinese medicine (TCM), can be used to manage and treat diabetes. Glycyrrhizic acid (GL) and its derivatives are suggested to be promising candidates for the treatment of T2DM and its complications. It is the principal bioactive constituent in licorice, one type of TCM.
  • 739
  • 12 Oct 2022
Topic Review
Anticancer Activity of Bee Venom Components against BC
While the survival rate has increased due to treatments for breast cancer, the quality of life has decreased because of the side effects of chemotherapy. Various toxins are being developed as alternative breast cancer treatments, and bee venom is drawing attention as one of them.
  • 370
  • 28 Jul 2022
Topic Review
Anticancer Activity of Pentagalloyl Glucose
Pentagalloyl glucose (PGG) is a natural hydrolyzable gallotannin abundant in various plants and herbs. It has a broad range of biological activities, specifically anticancer activities, and numerous molecular targets. PGG has a cytotoxic effect on many cancers, including prostate, breast, lung, head and neck, liver, leukemia, cervical, colorectal, and pancreatic cancers. PGG can affect different cancer stages and inhibit tumor growth through multiple mechanisms depending on cell origin, with minimal toxicity against normal cells. PGG targets several aberrant signal-transduction pathways that control cell growth and division, apoptosis, angiogenesis, and metastasis.
  • 203
  • 07 Jul 2023
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