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Topic Review
2-Phenylethanol
2-Phenylethanol (2-PE), also known as 2-phenethyl alcohol, is a higher aromatic alcohol characterized by one of the most popular and desired fragrances, which is the rosy scent.
  • 1.8K
  • 13 Jan 2022
Topic Review
SOS Family and Ras-GEFs
The SOS family of Ras-GEFs encompasses two highly homologous and widely expressed members, SOS1 and SOS2. Despite their similar structures and expression patterns, early studies of constitutive KO mice showing that SOS1-KO mutants were embryonic lethal while SOS2-KO mice were viable led to initially viewing SOS1 as the main Ras-GEF linking external stimuli to downstream RAS signaling, while obviating the functional significance of SOS2. Subsequently, different genetic and/or pharmacological ablation tools defined more precisely the functional specificity/redundancy of the SOS1/2 GEFs.
  • 1.8K
  • 05 Jul 2021
Topic Review
Edible Coatings
Edible coatings have been intensively developed and studied because of their capacity to improve the quality, shelf life, safety, and functionality of the treated products. Edible coatings can be applied through different techniques, like dipping, spraying, or coating, in order to control moisture transfer, gas exchange, or oxidative processes. Furthermore, some functional ingredients can be incorporated into an edible matrix and applied on the surface of foods, thus enhancing safety or even nutritional and sensory attributes. In the case of coated fruits and vegetables, their quality parameters, such as color, firmness, microbial load, decay ratio, weight loss, sensorial attributes, and nutritional parameters, are very specific to the type of products and their storage conditions should be carefully monitored.
  • 1.8K
  • 06 Jan 2022
Topic Review
Thymoquinone and COVID-19
Thymoquinone (TQ) is the most pharmacologically active ingredient in Nigella sativa seeds (black seeds); it is reported to have anticancer, anti-inflammatory and antioxidant effects in various settings.
  • 1.8K
  • 02 Jun 2021
Biography
Kadir Mısıroğlu
Türk Bilgesi Kadir Mısıroğlu (𐱅𐰇𐰼𐰜:𐰋𐰃𐰠𐰏𐰾𐰃:𐰴𐰑𐰼:𐰢𐰃𐰽𐰺𐰆𐰍𐰞𐰆) (24 January 1933 – 5 May 2019) was a Turkish historian, lawyer, writer, and publisher.[1][2][3] [4][5] His character is integrated with the fez. Radical Islamist and Ottomanist. He is known for his outspoken stance against Mustafa Kemal's reforms and Kemalism.[6][7] Ka
  • 1.8K
  • 23 May 2024
Topic Review
Peumo (Cryptocarya alba), a Native Fruit of Chile
The peumo (Cryptocarya alba) is a native fruit from central Chile that belongs to the Lauraceae family. To characterize the development and the potential health benefits of this edible fruit, quality and physiological parameters, along with antioxidant capacity, were evaluated during three clearly defined developmental stages of the fruit in two seasons. 
  • 1.8K
  • 10 Jan 2022
Topic Review
Mustard Oil Bomb
"Mustard oil bomb" is present in the order of Brassicales, including many Brassica vegetables that humans consume. Although it has beneficial value to human nutrition and health, plants evolved the mustard oil bomb for their defense. Glucosinolates and myrosinases are the key components of the bomb. In this brief entry, we describe the building-blocks of the mustard oil bomb and how it functions in plant defense against pathogens and insects.
  • 1.8K
  • 19 Dec 2020
Topic Review
Monoculture
Monoculture is the agricultural practice of producing or growing a single crop, plant, or livestock species, variety, or breed in a field or farming system at a time. Polyculture, where more than one crop is grown in the same space at the same time, is the alternative to monoculture. Monoculture is widely used in both industrial farming and organic farming and has allowed increased efficiency in planting and harvest. Continuous monoculture, or monocropping, where the same species is grown year after year, can lead to the quicker buildup of pests and diseases, and then rapid spread where a uniform crop is susceptible to a pathogen. The practice has been criticized for its environmental effects and for putting the food supply chain at risk. Diversity can be added both in time, as with a crop rotation or sequence, or in space, with a polyculture. Oligoculture has been suggested to describe a crop rotation of just a few crops, as is practiced by several regions of the world. The term monoculture is frequently applied for other uses to describe any group dominated by a single variety, e.g. social monoculturalism, or in the field of musicology to describe the dominance of the American and British music-industries in Western pop music, or in the field of computer science to describe a group of computers all running identical software.
  • 1.8K
  • 28 Nov 2022
Topic Review
Tricarboxylic Acid (TCA) Cycle Intermediates
The tricarboxylic acid cycle (TCA) is a series of chemical reactions used in aerobic organisms to generate energy via the oxidation of acetylcoenzyme A (CoA) derived from carbohydrates, fatty acids and proteins. 
  • 1.8K
  • 20 Feb 2021
Topic Review
Vitamin D, Oxidative-Stress and Aging
Recent advances in vitamin D research indicate that this vitamin, a secosteroid hormone, has beneficial effects on several body systems other than the musculoskeletal system. Both 25 dihydroxy vitamin D [25(OH)2D] and its active hormonal form, 1,25-dihydroxyvitamin D [1,25(OH)2D] are essential for human physiological functions, including damping down inflammation and the excessive intracellular oxidative stresses. Vitamin D is one of the key controllers of systemic inflammation, oxidative stress and mitochondrial respiratory function, and thus, the aging process in humans. In turn, molecular and cellular actions form 1,25(OH)2D slow down oxidative stress, cell and tissue damage, and the aging process. On the other hand, hypovitaminosis D impairs mitochondrial functions, and enhances oxidative stress and systemic inflammation. The interaction of 1,25(OH)2D with its intracellular receptors modulates vitamin D–dependent gene transcription and activation of vitamin D-responsive elements, which triggers multiple second messenger systems. Thus, it is not surprising that hypovitaminosis D increases the incidence and severity of several age-related common diseases, such as metabolic disorders that are linked to oxidative stress. These include obesity, insulin resistance, type 2 diabetes, hypertension, pregnancy complications, memory disorders, osteoporosis, autoimmune diseases, certain cancers, and systemic inflammatory diseases. Vitamin D adequacy leads to less oxidative stress and improves mitochondrial and endocrine functions, reducing the risks of disorders, such as autoimmunity, infections, metabolic derangements, and impairment of DNA repair; all of this aids a healthy, graceful aging process. Vitamin D is also a potent anti-oxidant that facilitates balanced mitochondrial activities, preventing oxidative stress-related protein oxidation, lipid peroxidation, and DNA damage. New understandings of vitamin D-related advances in metabolomics, transcriptomics, epigenetics, in relation to its ability to control oxidative stress in conjunction with micronutrients, vitamins, and antioxidants, following normalization of serum 25(OH)D and tissue 1,25(OH)2D concentrations, likely to promise cost-effective better clinical outcomes in humans. 
  • 1.8K
  • 29 Oct 2020
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