Subject:
All Disciplines Arts & Humanities Biology & Life Sciences Business & Economics Chemistry & Materials Science Computer Science & Mathematics Engineering Environmental & Earth Sciences Medicine & Pharmacology Physical Sciences Public Health & Healthcare Social Sciences
Sort:
Hottest Latest Alphabetical (A-Z) Alphabetical (Z-A)
Type:
All Topic Review Biography
Topic Review
UNC80 Deficiency
UNC80 deficiency is a severe disorder characterized by nervous system and developmental problems that are apparent from birth or early infancy. The disorder does not typically get worse over time; development of intellectual function and motor skills, such as rolling over and sitting, is slow and limited, but once skills are learned, they are usually retained.  
  • 536
  • 23 Dec 2020
Topic Review
UNC
UNC is a set of proteins first identified through a set of screening tests in Caenorhabditis elegans, looking for roundworms with movement problems. Worms with which were un-coordinated (hence UNC) were analysed in order to identify the genetic defect. Such proteins include UNC-5, a receptor for UNC-6 which is one of the netrins. Netrins are a class of proteins involved in axon guidance. UNC-5 uses repulsion (genetics) to direct axons while the other netrin receptor UNC-40 attracts axons to the source of netrin production.
  • 215
  • 18 Oct 2022
Topic Review
Umbilical Cord Blood-Derived sEV
Small extracellular vesicles (sEV) are a group of particles of nanometric size, released by virtually all cells. These vesicles function as biologic messengers, carrying proteins, lipids and nucleic acids as a form of paracrine cellular communication. Umbilical cord blood (UCB) is a priviledged source of sEV, due to its abundance in naïve cells with strong regenerative and immunomodulatory potential. Hence, UCB-derived sEV can be exploited for their therapeutic properties, taking advantage of nature's tools for achieving homeostasis.
  • 587
  • 29 Sep 2021
Topic Review
Umbilical Cord Blood Stem-Cell Transplantations
One of the biggest concern in blood transplantations is the graft-versus-host disease (GVHD) because its chronicity is a leading cause of morbidity and mortality. In this regard, umblical cord blood transplantations (UCBT) is a preferable source of donor hematopoietic stem cells (HSCs) compared to bone marrow transplantation (BMT). In this report, the authors provide strategies to expand umbilical stem cells and enhance efficacy of transplantation into indicated patients with chronic diseases (e.g. cancers, non malignant hemoglobinopathies).
  • 430
  • 18 Dec 2020
Topic Review
Ulva (Enteromorpha) Polysaccharides and Oligosaccharides
The high-valued utilization of Ulva (previously known as Enteromorpha) bioresources has drawn increasing attention due to the periodic blooms of world-wide green tide. The polysaccharide is the main functional component of Ulva and exhibits various physiological activities. The Ulva oligosaccharide as the degradation product of polysaccharide not only possesses some obvious activities, but also possesses excellent solubility and bioavailability. Both Ulva polysaccharides and oligosaccharides hold promising potential in the food industry as new functional foods or food additives. Studies on Ulva polysaccharides and oligosaccharides are increasing and have been the focus of the marine bioresources field.
  • 2.4K
  • 19 Mar 2022
Topic Review
Ultraviolet Reactors for Nonsolid Food Pasteurization
UV-C is an increasingly popular option for the pasteurization of non-solid plant-based foods because it is germicidal, economical, and environmentally-friendly. It is a proven alternative to conventional thermal processes for inactivating microorganisms.UV-C irradiation in nonsolid foods can be performed in equipment that either uses batch or continuous operation modes.
  • 505
  • 30 Aug 2023
Topic Review
Ultraviolet Radiation and Chronic Inflammation
The process of skin carcinogenesis is still not fully understood. Both experimental and epidemiological evidence indicate that chronic inflammation is one of the hallmarks of microenvironmental-agent-mediated skin cancers and contributes to its development. Maintaining an inflammatory microenvironment is a condition leading to tumor formation. Multiple studies focus on the molecular pathways activating tumorigenesis by inflammation and indicate several biomarkers and factors that can improve diagnostic and prognostic processes in oncology and dermatology. Reactive oxygen species produced by ultraviolet radiation, oxidizers, or metabolic processes can damage cells and initiate pro-inflammatory cascades. Considering the potential role of inflammation in cancer development and metastasis, the identification of early mechanisms involved in carcinogenesis is crucial for clinical practice and scientific research. Moreover, it could lead to the progress of advanced skin cancer therapies.
  • 482
  • 23 Apr 2021
Topic Review
Ultraviolet Protection in the Cornea
Ultraviolet (UV) irradiation induces DNA lesions in all directly exposed tissues. In the human body, two tissues are chronically exposed to UV: the skin and the cornea. The most frequent UV-induced DNA lesions are cyclobutane pyrimidine dimers (CPDs) that can lead to apoptosis or induce tumorigenesis. Lacking the protective pigmentation of the skin, the transparent cornea is particularly dependent on nucleotide excision repair (NER) to remove UV-induced DNA lesions. The DNA damage response also triggers intracellular autophagy mechanisms to remove damaged material in the cornea. Therapeutic solutions involving xenogenic DNA-repair enzymes such as T4 endonuclease V or photolyases exist and are widely distributed for dermatological use. 
  • 553
  • 23 Mar 2022
Topic Review
Ultraviolet Light
Ultraviolet (UV) light is a dry and biologically inert process that decreases the microorganism count by around 99.9% with minimum heating of the packing material. Between the UV lamp and the area to be disinfected, there should be no obstruction. Since dirt absorbs radiation and thereby protects bacteria, the effectiveness of this application is therefore dependent on the sanitation of the material surfaces.
  • 1.7K
  • 10 Aug 2021
Topic Review
Ultrastructural Features of the Blood-Brain Barrier
The blood-brain barrier (BBB) is a dynamic barrier separating neurocytes and brain tissues from blood that is extremely sealed and strictly regulated by transporters such as aquaporin-4 (AQP-4), glucose transporter (GLUT), and specialized tight junctional complexes (TJCs) including tight junctions (TJs), adherens junctions (AJs), and Zonulae occludens (ZOs). With specifically selective transcellular and paracellular permeability, the BBB maintains a homeostatic microenvironment to protect the central nervous system (CNS).
  • 312
  • 27 Jul 2023
  • Page
  • of
  • 1814
Featured Entry Collections
>>

Featured Books

>>
Encyclopedia of Social Sciences
Encyclopedia of COVID-19
Encyclopedia of Fungi
Encyclopedia of Digital Society, Industry 5.0 and Smart City
Video Production Service
Feedback