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Topic Review
Utilization of Fossil Shell Flour in Beef Production
Population growth in many countries results in increased demand for livestock production and quality products. However, beef production represents a complex global sustainability challenge, including meeting the increasing demand and the need to respond to climate change and/or greenhouse gas emissions. Several feed resources and techniques have been used but have some constraints that limit their efficient utilization which include being product-specific, not universally applicable, and sometimes compromising the quality of meat. This evokes a need for novel techniques that will provide sustainable beef production and mitigate the carbon footprint of beef while not compromising beef quality. Fossil shell flour (FSF) is a natural additive with the potential to supplement traditional crops in beef cattle rations in response to this complex global challenge as it is cheap, readily available, and eco-friendly. 
  • 137
  • 01 Feb 2024
Topic Review
Utilization Methods for Lignocellulosic Biomass
Utilization of lignocellulosic biomass (LCB) for bioenergy production has been widely investigated in the previous decades, as it provides an excellent environmentally friendly alternative to non-renewable energy sources. There are numerous procedures to convert plant-based biomass into usable feedstock or valuable energy carriers, such as C5 and C6 sugars, organic acids, or more commonly, bioethanol and biogas. 
  • 162
  • 23 Oct 2023
Topic Review
Utility of Retinal Organoids
The eye is one of the most important sensory organs in humans, providing us with a valuable remote sense, vision. A wealth of information enters the visual system through the eyes, creating complex images with shapes, colors, and textures. Despite the progress of modern medicine in the last decades, millions of people diagnosed with retinal dystrophies (RDs), such as retinitis pigmentosa (RP), or age-related diseases, such as age-related macular degeneration (AMD), are suffering from severe visual impairment or even legal blindness. On one hand, the reprogramming of somatic cells into induced pluripotent stem cells (iPSCs) and the progress of three-dimensional (3D) retinal organoids (ROs) technology provide a great opportunity to study, understand, and even treat retinal diseases. On the other hand, research advances in the field of electronic retinal prosthesis using inorganic photovoltaic polymers and the emergence of organic semiconductors represent an encouraging therapeutical strategy to restore vision to patients at the late onset of the disease.
  • 365
  • 18 Mar 2022
Topic Review
Uterine Natural Killer Cells
Reproductive immunology is at the forefront of research interests, aiming to better understand the mechanisms of immune regulation during gestation. The relationship between the immune system and the implanting embryo is profound because the embryo is semi-allogenic but not targeted by the maternal immune system, as expected in graft-versus-host reactions. The most prominent cell population at the maternal–fetal interface is the population of uterine natural killer (uNK) cells. Uterine NK cells are two-faced immunologically active cells, bearing comparison with Janus, the ancient Roman god of beginnings and endings. 
  • 211
  • 30 Oct 2023
Topic Review
Usutu virus in Europe
Usutu virus (USUV) is an emerging arbovirus isolated in 1959 (Usutu River, Swaziland). Previously restricted to sub-Saharan Africa, the virus was introduced in Europe in 1996. While USUV has received little attention in Africa, the virus emergence has prompted numerous studies with robust epidemiological surveillance programs in Europe. Epizootics and genetic diversity of USUV in different bird species as well as detection of the virus in mosquitoes suggest repeated USUV introductions into Europe with endemization in some countries. The zoonotic potential of USUV has been reported in a growing number of human cases. Clinical cases of neuroinvasive disease and USUV fever, as well as seroconversion in blood donors were reported in Europe since 2009. Since spreading trends of USUV are likely to continue, continuous multidisciplinary interventions ('One Health' concept) should be conducted for monitoring and prevention of this emerging arboviral infection.
  • 1.3K
  • 26 Oct 2020
Topic Review
Ustilago Maydis
Ustilago maydis is a smut fungus that infects all aerial maize organs, namely, seedling leaves, tassels, and ears.
  • 744
  • 19 Feb 2021
Topic Review
Using Pulses in Baked Products
Pulses—thanks to both nutritional and health-promoting features, together with their low environmental impact—satisfy the demand for high-protein/high-fiber products. However, their consumption is still somewhat limited in Western countries, due to the presence of antinutrient compounds including phytic acid, trypsin inhibitors, and some undigested oligosaccharides, which are responsible for digestive discomfort. Another limitation of eating pulses regularly is their relatively long preparation time. One way to increase the consumption of pulses is to use them as an ingredient in food formulations, such as bread and other baked products. 
  • 496
  • 20 Jul 2021
Topic Review
Using GPCRs to Target Ovarian Cancer with Nanomedicines
G protein-coupled receptors (GPCRs) are the largest family of membrane receptors, and many are overexpressed in solid tumors, including ovarian cancer.
  • 383
  • 19 May 2022
Topic Review
Using CO2 for Biomanufacturing of Fuels and Chemicals
Microbial cell factories offer an eco-friendly alternative for transforming raw materials into commercially valuable products because of their reduced carbon impact compared to conventional industrial procedures. These systems often depend on lignocellulosic feedstocks, mainly pentose and hexose sugars. One major hurdle when utilizing these sugars, especially glucose, is balancing carbon allocation to satisfy energy, cofactor, and other essential component needs for cellular proliferation while maintaining a robust yield. Nearly half or more of this carbon is inevitably lost as CO2 during the biosynthesis of regular metabolic necessities. This loss lowers the production yield and compromises the benefit of reducing greenhouse gas emissions—a fundamental advantage of biomanufacturing.
  • 192
  • 06 Dec 2023
Topic Review
Usher Syndrome
Usher syndrome is a condition characterized by partial or total hearing loss and vision loss that worsens over time.
  • 496
  • 23 Dec 2020
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