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Topic Review
Biography
Topic Review
Integrating (Nutri-)Metabolomics into the One Health Tendency
The term ‘metabolomics’ was introduced in the literature in 1998 and refers to the study of small molecules in a biological sample. In 2001, a group of biochemists founded the Society of Metabolomics, and the use of this technology in various fields of research has increased greatly since 2005. Nutrimetabolomics, or nutritional metabolomics, is an integral part of metabolomics with the goal of examining individual functional responses to different diets, analysing specific dietary biomarkers for targeted foods and diets, and investigating the interrelationship between risk factors for certain diseases and different diets both in the human and veterinary science fields.
292
06 Jul 2023
Topic Review
LncRNA Functional Screening in Organismal Development
Controversy continues over the functional prevalence of long non-coding RNAs (lncRNAs) despite their being widely investigated in all kinds of cells and organisms. In animals, lncRNAs have aroused general interest from exponentially increasing transcriptomic repertoires reporting their highly tissue-specific and developmentally dynamic expression, and more importantly, from growing experimental evidence supporting their functionality in facilitating organogenesis and individual fitness.
185
06 Jul 2023
Topic Review
Nanoparticles in Lung Cancer Treatment
Lung cancer is managed using conventional therapies, including chemotherapy, radiation therapy, or a combination of both. Each of these therapies has its own limitations, such as the indiscriminate killing of normal as well as cancer cells, the solubility of the chemotherapeutic drugs, rapid clearance of the drugs from circulation before reaching the tumor site, the resistance of cancer cells to radiation, and over-sensitization of normal cells to radiation. Other treatment modalities include gene therapy, immunological checkpoint inhibitors, drug repurposing, and in situ cryo-immune engineering (ICIE) strategy. Nanotechnology has come to the rescue to overcome many shortfalls of conventional therapies.
494
06 Jul 2023
Topic Review
Properties and Acne Treatment of Tea Tree Oil
Tea tree oil is an essential oil extracted from Melaleuca alternifolia (Maiden & Betch) Cheel with known antibacterial, anti-inflammatory, and antioxidant properties and widely used in cosmetic products to treat acne vulgaris.
389
06 Jul 2023
Topic Review
Relationship between Polysaccharides Structures and Their Bioactivities
Brown macroalgae polysaccharides are known for their several potential therapeutic properties; in fact, they are used as an ingredient or component in a wide range of industries, including pharmaceutical, medical, food, and cosmetics. The most promising activities are in the field of medicine due to their antiviral, anti-inflammatory, antioxidant, and anticarcinogenic actions.
342
06 Jul 2023
Topic Review
Predatory Bacteria
Predatory bacteria, along with the biology of their predatory behavior, have attracted interest in terms of their ecological significance and industrial applications.
365
06 Jul 2023
Topic Review
Neurological Disorders in Animals with NKA Mutations
Endogenous cardiotonic steroids are involved in the pathogenesis of affective disorders, including depression and bipolar disorder, which are linked to dopaminergic system dysfunction. Animal models have shown that the cardiotonic steroid ouabain induces mania-like behavior through dopamine-dependent intracellular signaling pathways. In addition, mutations in the alpha subunit of Na+,K+-ATPase lead to the development of neurological pathologies. Evidence from animal models confirms the neurological consequences of mutations in the Na+,K+-ATPase alpha subunit.
345
06 Jul 2023
Topic Review
Intestinal Mucosa-Associated Immune System—GALT
The intestinal mucosa is not only the primary site of nutrient digestion and absorption, but also the innate defence barrier against most intestinal pathogens. The intestinal barrier is in turn composed of a mechanical barrier, a biological barrier, a chemical barrier, and an immunological barrier.
563
06 Jul 2023
Topic Review
Red Beets as a Source of Bioactive Compounds
Beetroot (Beta vulgaris L.) is a vegetable that is consumed worldwide in the form of juices, soups, or salads. It is also known for its high content of biologically active substances such as betalains, polyphenolic compounds, vitamins, carotenoids, and other nutrients including, sodium, potassium, and magnesium. The distribution of these compounds in the plant is diverse, some occur in greater amounts in the leaves (e.g., vitamin A, B6) and others are in the tubers (e.g., folate, lycopene). The concentration of bioactive compounds in beetroot also depends on its variety and growing conditions.
606
05 Jul 2023
Topic Review
Traditional Balsamic Vinegar Processing
The most known and traditional vinegar is the one that is made from wine. For its production, the grape must undergo alcohol fermentation and the posterior oxidation of ethanol to acetic acid. Yeasts and acetic acid bacteria (AAB) carry out the biochemical processes in sequence. The process of wine acetification can be achieved by slow traditional processes (the Orléans or French methods) or by a quick submerged industrial process. High-quality vinegar is usually produced by traditional methods using oak casks, once the wood allows the continuous aeration of the acetic bacteria culture. Sour–sweet vinegar presents a balance of both bitter/sour and sweet flavors. The sourness typically comes from acetic acid, while the sweetness can come from the type of fruit or the amount of sugar present at the end of vinegar production. In general, sour-sweet vinegar has a more complex and nuanced flavor profile compared to regular vinegar, which is often simply sour. One kind of vinegar produced by wine acetification where yeasts and bacteria co-exist and produce savory vinegar is traditional balsamic vinegar (TBV).
1.0K
05 Jul 2023
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