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Topic Review
Atriplex Portulacoides as Functional Food
The halophyte Atriplex portulacoides (syn. Halimione portulacoides) occurs in habitats that are exposed to seawater inundations, and shows biochemical adaptations to saline and oxidative stresses. Its composition includes long chain lipids, sterols, phenolic compounds, glutathione, carotenoids,and micronutrients such as Fe, Zn, Co and Cu. The productivity of A. portulacoides in natural environments, and its adaptability to non-saline soils, make it a potential crop of high economic interest. This plant is suitable to be exploited as a functional food that is potentially able to reduce oxidative stress and inflammatory processes in humans and animals. This plant offers a valuable example of valorisation of the biodiversity for promoting the sustainability and diversification in agriculture.
  • 1.1K
  • 26 Nov 2020
Topic Review
Electrical Trap-and-Kill Fly Traps Using Electrified Insulated Conductors
Electrostatic insect exclusion is a physical approach to pest control in which an apparatus forming an electric field (EF) is applied to capture pests. The EF producer consisted of a negatively charged polyvinyl chloride membrane-insulated iron plate (N-PIP) and a non-insulated grounded iron plate (GIP) paralleled with the N-PIP. An EF was formed in the space between the plates. The magnitude of electric current from the fly was voltage-dependent, and detrimental effects caused by electricity release became more apparent as the applied voltage increased. Bioelectrical measurements showed that electric current caused acute damage and delayed the death of captured flies. 
  • 1.1K
  • 19 Apr 2022
Topic Review
NLRP3 Inflammasome in Neurodegenerative
Inflammasomes are intracellular multiprotein complexes in the cytoplasm that regulate inflammation activation in the innate immune system in response to pathogens and to host self-derived molecules. The NLRP3 belongs to the subfamily of NLRP which activates caspase 1, thus causing the production of proinflammatory cytokines (interleukin 1β and interleukin 18) and pyroptosis. This inflammasome is involved in multiple neurodegenerative and metabolic disorders including Alzheimer’s disease, multiple sclerosis, type 2 diabetes mellitus, and gout. 
  • 1.1K
  • 25 May 2022
Topic Review
Photorespiration: The Futile Cycle?
Photorespiration, or C2 photosynthesis, is generally considered a futile cycle that potentially decreases photosynthetic carbon fixation by more than 25%. Nonetheless, many essential processes, such as nitrogen assimilation, C1 metabolism, and sulfur assimilation, depend on photorespiration. Most studies of photosynthetic and photorespiratory reactions are conducted with magnesium as the sole metal cofactor despite many of the enzymes involved in these reactions readily associating with manganese. Indeed, when manganese is present, the energy efficiency of these reactions may improve. 
  • 1.1K
  • 19 May 2021
Topic Review
Equine Endometrium Morphology
Mares are seasonal polyestric. The morphology of the healthy equine endometrium is influenced by the season of the year, the stage of the endometrial cycle, as well as the presence of endometrial diseases. The latter have an impact on the wellbeing of individual mares and can also inflict major financial losses for the horse breeding industry. The microscopic examination of an endometrial biopsy is an important diagnostic tool, since it can also detect subclinical diseases. This review provides an overview about morphological and molecular features of the healthy and diseased equine endometrium. It reviews the diagnostic findings of inflammatory and degenerative endometrial disease of mares, as well as the current state of knowledge regarding their cellular and molecular pathogenesis. It further shows that the comparative evaluation of morphological features and molecular characteristics of the healthy and diseased equine endometrium is an important prerequisite for the identification of disease-associated molecular markers, which in turn will facilitate the development of diagnostic and predictive biomarkers, as well as novel prophylactic and therapeutic options. Although currently numerous molecular data are already available, future studies are required to establish their translation into clinical practice.
  • 1.1K
  • 01 Nov 2020
Topic Review
Atomic Force Microscopy
Atomic force microscopy (AFM) is one of the microscopic techniques with the highest lateral resolution. It can usually be applied in air or even in liquids, enabling the investigation of a broader range of samples than scanning electron microscopy (SEM), which is mostly performed in vacuum. Since it works by following the sample surface based on the force between the scanning tip and the sample, interactions have to be taken into account, making the AFM of irregular samples complicated, but on the other hand it allows measurements of more physical parameters than pure topography.
  • 1.1K
  • 06 Apr 2022
Topic Review
Oral Cavity during Viral and Bacterial Infections
Several viral diseases often affect the oral cavity; for example, human immunodeficiency virus (HIV) infection may initially present with oral lesions, human papillomavirus (HPV) infection often increases the risk of developing oral squamous cell carcinoma, and oral damage has been documented during hepatitis B and C virus infections
  • 1.1K
  • 13 Oct 2022
Topic Review
EV-Based Vaccines
Extracellular vesicles (EVs) are secreted from almost all human cells and mediate intercellular communication by transferring heterogeneous molecules (i.e., DNA, RNAs, proteins, and lipids). In this way, EVs participate in various biological processes, including immune responses. Viruses can hijack EV biogenesis systems for their dissemination, while EVs from infected cells can transfer viral proteins to uninfected cells and to immune cells in order to mask the infection or to trigger a response. Several studies have highlighted the role of native or engineered EVs in the induction of B cell and CD8(+) T cell reactions against viral proteins, strongly suggesting these antigen-presenting EVs as a novel strategy for vaccine design, including the emerging COVID-19. EV-based vaccines overcome some limitations of conventional vaccines and introduce novel unique characteristics useful in vaccine design, including higher bio-safety and efficiency as antigen-presenting systems and as adjuvants.
  • 1.1K
  • 02 Feb 2021
Topic Review
Lactic Acid Bacteria in Raw-Milk Cheeses
Lactic acid bacteria (LAB) are of great economic importance because they play an important role throughout the fermentation process of traditional cheeses when added accidentally or intentionally. Their metabolic features not only contribute to the development of desirable sensory characteristics of food products but also allow the nutritional value of the raw material to be maintained or even enhanced.
  • 1.1K
  • 05 Aug 2022
Topic Review
The Gut Microbiome in NAFLD
Non-alcoholic fatty liver disease (NAFLD) is a multifactorial disease in which environmental and genetic factors are involved. Although the molecular mechanisms involved in NAFLD onset and progression are not completely understood, the gut microbiome (GM) is thought to play a key role in the process, influencing multiple physiological functions. 
  • 1.1K
  • 30 Oct 2020
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