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Topic Review
Polysaccharides as Feed Additives for Methane Mitigation
Marine algal polysaccharides have emerged as a promising research avenue because of their abundance and sustainability. Polysaccharides, such as alginate, laminaran, and fucoidan, which are extracted from marine seaweeds, have demonstrated the potential to reduce methane emissions by influencing the microbial populations in the rumen.
  • 332
  • 04 Aug 2023
Topic Review
Peripheral Mitochondrial Dysfunction and Alzheimer’s Disease
Alzheimer’s disease (AD) is a progressive disease, where dementia symptoms gradually worsen. The causes of AD are complex and are characterized by changes in the brain that lead to the accumulation of two proteins, amyloid beta and tau, forming structures called plaques and tangles, respectively. It is challenging to identify the mechanisms for the initiation and progression of AD. Oxidative stress and inflammation derived from peripheral mitochondrial dysfunction have also been suggested as alternative contributors of AD pathogenesis.
  • 566
  • 04 Aug 2023
Topic Review
Nutraceutical Plant Products on Rabbit Production and Health
Plant/botanical products are natural and vital substances widely used as dietary additives in livestock farms. They contain phytobiotics, phenols, flavonoids, tannins, and essential oils, which play a multitude of roles in a rabbit’s body. The nutritional and medicinal properties of these substances mainly influence animal performance by improving digestion and enhancing immunity/health. Additionally, several botanical products, including herbs, are considered phytogenic feed additives for livestock to improve growth performance and health status.
  • 278
  • 04 Aug 2023
Topic Review
Extracellular Vesicles and Inflammatory Diseases
Inflammation is the defense mechanism of the immune system against harmful stimuli such as pathogens, toxic compounds, damaged cells, radiation etc. and characterized by tissue redness, swelling, heat generation, pain, and loss of tissue functions. Inflammation is essential in the recruitment of immune cells at the site of infection, which not only aids in the elimination of the cause, but also initiates the healing process. However, prolonged inflammation often brings about several chronic inflammatory disorders, hence, a balance between the pro- and anti-inflammatory responses is essential in order to eliminate the cause while producing least damage to the host. Growing body of evidence indicates that extracellular vesicles (EVs) play a major role in cell-cell communication via the transfer of bioactive molecules in the form of proteins, lipids, DNA, RNAs, miRNAs etc. between the cells.
  • 390
  • 03 Aug 2023
Topic Review
Phytochemical Properties, Extraction, and Pharmacological Benefits of Naringin
Naringin is a nutritional flavanone glycoside that has been shown to be effective in the treatment of a few chronic disorders associated with ageing. Citrus fruits contain a common flavone glycoside that has specific pharmacological and biological properties. Naringin, a flavone glycoside with a range of intriguing characteristics, is abundant in citrus fruits. Naringin has been shown to have a variety of biological, medicinal, and pharmacological effects. Naringin is hydrolyzed into rhamnose and prunin by the naringinase, which also possesses l-rhamnosidase activity. D-glucosidase subsequently catalyzes the hydrolysis of prunin into glucose and naringenin. Naringin is known for having anti-inflammatory, antioxidant, and tumor-fighting effects. Numerous test animals and cell lines have been used to correlate naringin exposure to asthma, hyperlipidemia, diabetes, cancer, hyperthyroidism, and osteoporosis.
  • 513
  • 03 Aug 2023
Topic Review
Climate Change and Salmonid Distribution
Salmonids are a cold-water species. Global warming will generally have a major impact on their success. Historically, climatic variability has affected the patterns of abundance in Atlantic salmon and Pacific salmon populations. Climate change will continue to affect not only smolting and migration but also instream habitats across all seasons.
  • 261
  • 03 Aug 2023
Topic Review
Extracellular Vesicles Derived from Mesenchymal Stem Cells
Mesenchymal stem cell-derived extracellular vesicles (MSC-EVs) are biologically active substances secreted by MSCs into the extracellular matrix that play an immunomodulatory role in skin damage repair.
  • 264
  • 03 Aug 2023
Topic Review
Aflatoxin Contamination and Soils Control
Aflatoxins are potent carcinogenic compounds, mainly produced by fungi species of the genus Aspergillus in the soil. Because of their stability, they are difficult to remove completely, even under extreme conditions. Aflatoxin contamination is one of the main causes of safety in peanuts, maize, wheat and other agricultural products. Aflatoxin contamination originates from the soil. 
  • 334
  • 03 Aug 2023
Topic Review
Dysregulation of mir-106a in Non-Cancer Diseases
MicroRNAs (miRNAs) comprise a class of non-coding RNA with extensive regulatory functions within cells. MiR-106a is recognized for its super-regulatory roles in vital processes. MicroRNAs (miRNAs) are small, endogenous, non-coding RNAs that control gene expression at the translation and even transcription levels. miRNAs are critical regulators of biological processes, including cellular proliferation, differentiation, development, apoptosis, and modulation of the host response to viral infection.
  • 402
  • 03 Aug 2023
Topic Review
Mouse Models of Autism Spectrum Disorders
Autism spectrum disorder (ASD) is a neurodevelopmental condition with a prevalence rate of 2.78%, and it is characterized by deficits in sociability and communication and restricted patterns of interests and activities. Remarkably, this psychiatric disorder exhibits a pronounced gender bias, with 80% of children diagnosed with ASD being boys.
  • 410
  • 03 Aug 2023
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