Subject:
All Disciplines Arts & Humanities Biology & Life Sciences Business & Economics Chemistry & Materials Science Computer Science & Mathematics Engineering Environmental & Earth Sciences Medicine & Pharmacology Physical Sciences Public Health & Healthcare Social Sciences
Sort:
Hottest Latest Alphabetical (A-Z) Alphabetical (Z-A)
Type:
All Topic Review Biography
Topic Review
Inflammasomes in Inflammatory Diseases
Inflammasomes, a group of multiprotein complexes, are essential in regulating inflammation and immune responses. Several inflammasomes, including nucleotide-binding domain leucine-rich repeat-containing protein 1 (NLRP1), NLRP3, NLRP6, NLRP7, NLRP12, interferon-inducible protein 16 (IFI16), NOD-like receptor family CARD domain-containing protein 4 (NLRC4), absent in melanoma 2 (AIM2), and pyrin, have been studied in various inflammatory diseases. Activating inflammasomes leads to the processing and production of proinflammatory cytokines, such as interleukin (IL)-1β and IL-18. The NLRP3 inflammasome is the most extensively studied and well characterized. Consequently, targeting inflammasomes (particularly NLRP3) with several compounds, including small molecule inhibitors and natural compounds, has been studied as a potential therapeutic strategy. 
  • 219
  • 17 Nov 2023
Topic Review
Cutibacterium acnes Dysbiosis
This research presents the virulence factors, clinical relevance, and current treatments of C. acnes, highlighting its association with AV, post-surgical infections, and other diseases. It also explores alternative innovative therapies such as phage therapy in development/research that are gaining prominence, with a growing focus on personalized medical approaches.
  • 313
  • 17 Nov 2023
Topic Review
Effects of Physical Activity and Type 2 Diabetes
Type 2 diabetes mellitus (T2DM) is one of the most widespread diseases worldwide. Lifestyle interventions, including diet and physical activity (PA), are fundamental non-pharmacological components of T2DM therapy. Exercise interventions are strongly recommended for people with or at risk of developing or already with overt diabetes, but adherence to PA guidelines in this population is still challenging. Furthermore, the heterogeneity of T2DM patients, driven by differing residual β-cell functionality, as well as the possibility of practicing different types and intensities of PA, has led to the need to develop tailored exercise and training plans.
  • 303
  • 17 Nov 2023
Topic Review
The Molecular Mechanisms of Complement Receptor 1
Human complement receptor 1 (CR1) is a membrane-bound regulator of complement that has been the subject of attempts to generate soluble therapeutic compounds comprising different fragments of its extracellular domain. 
  • 291
  • 17 Nov 2023
Topic Review
Influence factor of Biochar Functions in Soil
Biochar effects are strongly dependent on its properties. Biochar improves physical soil properties by decreasing bulk density and increasing medium and large aggregates, leading to faster and deeper water infiltration and root growth. Improvement of the chemical properties of soil is connected with pH neutralization of acidic soils, increase of cation exchange capacity and base saturation, providing a larger surface for sorption of toxicants and exchange of cations. Biochar increases the stocks of macro- and micronutrients in soil and remains sufficient for decades.
  • 219
  • 17 Nov 2023
Topic Review
Intracellular Functions of Caveolin-1
Caveolin-1 (Cav1) is a protein that exists in many different forms and locations in cells and tissues throughout the body. We can understand more about cell growth, death, and cellular processes by further understanding the structure and function of Cav1. The increasing knowledge of Cav1 and its roles in different organs and disease processes helps delineate its potential use in the development of treatments and therapies.
  • 237
  • 17 Nov 2023
Topic Review
Cattle Feeding Precision by Automatic Feeding Systems
Livestock farming is experiencing a significant shift towards automation to reduce the many repetitive tasks requiring little skills and high workloads. For farmers, automatic feeding systems for ruminants can be an excellent way to reduce their daily workload and improve animal welfare and production quality. Studies have demonstrated that adopting automatic feeding systems leads to lower energy requirements, lower feed waste, and improved animal welfare, which unequivocally aligns with the farmers' perspective. However, to maximize the flexibility of the feeding robots and reap the benefits, thorough economic and structural planning that considers all of the farming site's features is necessary. Additionally, automatic feeding systems can help involve younger generations in animal farming and increase inclusivity, which may foster female entrepreneurship, all while maintaining good feeding practices.
  • 578
  • 17 Nov 2023
Topic Review
Alternative Management of Fungal Diseases in Plants
Fungal pathogens pose a major threat to food production worldwide. Traditionally, chemical fungicides have been the primary means of controlling these pathogens, but many of these fungicides have recently come under increased scrutiny due to their negative effects on the health of humans, animals, and the environment. Furthermore, the use of chemical fungicides can result in the development of resistance in populations of phytopathogenic fungi. Therefore, new environmentally friendly alternatives that provide adequate levels of disease control are needed to replace chemical fungicides—if not completely, then at least partially. A number of alternatives to conventional chemical fungicides have been developed, including plant defence elicitors (PDEs); biological control agents (fungi, bacteria, and mycoviruses), either alone or as consortia; biochemical fungicides; natural products; RNA interference (RNAi) methods; and resistance breeding. 
  • 169
  • 16 Nov 2023
Topic Review
Aquatic and Terrestrial Invertebrate Welfare
Invertebrates are a diverse group of animals that make up the majority of the animal kingdom and encompass a wide array of species with varying adaptations and characteristics. Invertebrates are found in nearly all of the world’s habitats, including aquatic, marine, and terrestrial environments.
  • 677
  • 16 Nov 2023
Topic Review
Developmental Implications of Muscle-Targeted Magnetic Mitohormesis
Muscle function reflects muscular mitochondrial status, which, in turn, is an adaptive response to physical activity, representing improvements in energy production for de novo biosynthesis or metabolic efficiency. Differences in muscle performance are manifestations of the expression of distinct contractile-protein isoforms and of mitochondrial-energy substrate utilization. Powerful contractures require immediate energy production from carbohydrates outside the mitochondria that exhaust rapidly. Sustained muscle contractions require aerobic energy production from fatty acids by the mitochondria that is slower and produces less force. 
  • 659
  • 16 Nov 2023
  • Page
  • of
  • 1815
Featured Entry Collections
>>

Featured Books

>>
Encyclopedia of Social Sciences
Encyclopedia of COVID-19
Encyclopedia of Fungi
Encyclopedia of Digital Society, Industry 5.0 and Smart City
ScholarVision Creations
Feedback