Topic Review
Raisins
Raisins are dried grapes consumed worldwide that contain beneficial components for human health. They are rich in fiber and phytochemicals such as phenolic compounds. Despite a 60% sugar content, several studies have reported health-promoting properties for raisins and this review compiles the intervention studies, as well as the cell line and animal model studies carried out to date. It has been demonstrated that raisins possess a low-to-moderate glycemic index, which makes them a healthy snack. They seem to contribute to a better diet quality and may reduce appetite. Their antioxidant capacity has been correlated to the phenolic content and this may be involved in the improvement of cardiovascular health. In addition, raisins maintain a good oral health due to their antibacterial activity, low adherence to teeth and an optimum oral pH. Raisin consumption also seems to be favorable for colon function, although more studies should be done to conclude this benefit. Moreover, gut microbiota could be affected by the prebiotic content of raisins. Cell line and animal model studies show other potential benefits in specific diseases, such as cancer and Alzheimer’s disease. However, deeper research is required and future intervention studies with humans are needed. Overall, incorporating an 80–90 g portion of raisins (half a cup) into the daily diet may be favorable for human health.
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  • 29 Oct 2020
Topic Review
Coffee Leaf Miner Leucoptera coffeella
The coffee leaf miner (CLM) Leucoptera coffeella moth is a major threat to coffee production. Insect damage is related to the feeding behavior of the larvae on the leaf. During the immature life stages, the insect feeds in the mesophyll triggering necrosis and causing loss of photosynthetic capacity, defoliation and significant yield loss to coffee crops. Chemical control is used to support the coffee production chain, though market requirements move toward conscious consumption claiming for more sustainable methods.
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  • 22 Dec 2021
Topic Review
Phospholipids
Phospholipids are unique and versatile molecules. They are of natural occurrence and the main components in cellular membranes. Arranged as a lipid bilayer, phospholipids play a significant role in the structure and functionality of biological membranes. They are amphiphilic and consist of a hydrophilic headgroup and a lipophilic/hydrophobic tail.
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  • 04 Feb 2021
Topic Review
Non-Native Guinea Grass
Guinea grass (Panicum maximum Jacq., renamed Megathyrsus maximus Jacq.) is a native forage plant in Africa of great economic value, but it was introduced in almost all tropical countries as a source of animal forage.
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  • 30 Jun 2021
Topic Review
Myeloid-Derived Suppressor Cells in Cancer
The emergence of immunotherapy has been an astounding breakthrough in cancer treatments. In particular, immune checkpoint inhibitors, targeting PD-1 and CTLA-4, have shown remarkable therapeutic outcomes. However, response rates from immunotherapy have been reported to be varied, with some having pronounced success and others with minimal to no clinical benefit. An important aspect associated with this discrepancy in patient response is the immune-suppressive effects elicited by the tumour microenvironment (TME). Immune suppression plays a pivotal role in regulating cancer progression, metastasis, and reducing immunotherapy success. Most notably, myeloid-derived suppressor cells (MDSC), a heterogeneous population of immature myeloid cells, have potent mechanisms to inhibit T-cell and NK-cell activity to promote tumour growth, development of the pre-metastatic niche, and contribute to resistance to immunotherapy. Accumulating research indicates that MDSC can be a therapeutic target to alleviate their pro-tumourigenic functions and immunosuppressive activities to bolster the efficacy of checkpoint inhibitors.
  • 2.3K
  • 25 May 2021
Topic Review
Embodied 'Basic' Emotions in Chinese and English Language
References to the body are one feature shared across languages, particularly when describing the mental processes of emotion, reflecting the embodiment of an emotional experience. Embodied emotion concepts encompass these categorized outcomes of bidirectional brain–body interactions yet can be differentiated further into afferent or interoceptive and efferent or autonomic processes. Between languages, a comparison of emotion words indicates the dominance of afferent or interoceptive processes in how embodied emotions are conceptualized in Chinese, while efferent or autonomic processes feature more commonly in English. Correspondingly, in linguistic expressions of emotion, Chinese-speaking people are biased toward being more receptive, reflective, and adaptive, whereas native English speakers may tend to be more reactive, proactive, and interactive. 
  • 2.3K
  • 05 Aug 2022
Topic Review
Beer Brewed from Sorghum
Beer is a complex beverage system despite being made up of only four ingredients: yeast, water, hops, and malted grain. Typically, malted barley is used as the primary grain source for brewing, however alternative grains/pseudo-grains like sorghum are gaining popularity. However, the use of sorghum in beer manufacturing does have its issues, which are largely due to its low amylolytic activity (which is insufficient for complete saccharification), high gelatinization temperature, and low free amino content. Sorghum malt has a higher concentration of alpha-amylase and a lower concentration of beta-amylase compared to malted barley. Due to the reduced enzymatic activity of sorghum this deficiency can lead to insufficient production of fermentable sugars, high dextrin content, and increased viscosity. Due to sorghum’s higher gelatinization temperature, the hydrolysis of sugars into fermentable sugars is only partially completed. Thus, resulting in fewer fermentable sugars for the yeast to metabolize for the production of ethanol, and volatile and semi-volatile compounds.
  • 2.3K
  • 17 Aug 2021
Biography
Jimmy Dore
James Patrick Anthony Dore (born July 26, 1965) is an American stand-up comedian and political commentator. He hosts The Jimmy Dore Show, a talk show on YouTube formerly affiliated with The Young Turks. Dore's material frequently criticizes the Democratic Party from a left-wing perspective. Dore was born in southwest Chicago , Illinois, on July 26, 1965, into a Catholic family of Polish and I
  • 2.2K
  • 30 Nov 2022
Topic Review
Rhinovirus
Rhinoviruses (RVs) are non-enveloped positive sense RNA viruses with a lifecycle fully contained within the cytoplasm. Despite decades of study, the details of how RVs exit the infected cell are still unclear. Current literature strongly suggests a role for necroptosis and/or autophagy in RV release, with the caveat that all the literature is based on RV-A and RV-B strains, with no studies to date examining the interaction of RV-C strains with cell death pathways.
  • 2.2K
  • 15 Jun 2021
Topic Review
Antenna
Antennae (Template:Singular antenna), sometimes referred to as "feelers", are paired appendages used for sensing in arthropods. Antennae are connected to the first one or two segments of the arthropod head. They vary widely in form but are always made of one or more jointed segments. While they are typically sensory organs, the exact nature of what they sense and how they sense it is not the same in all groups. Functions may variously include sensing touch, air motion, heat, vibration (sound), and especially smell or taste. Antennae are sometimes modified for other purposes, such as mating, brooding, swimming, and even anchoring the arthropod to a substrate. Larval arthropods have antennae that differ from those of the adult. Many crustaceans, for example, have free-swimming larvae that use their antennae for swimming. Antennae can also locate other group members if the insect lives in a group, like the ant. The common ancestor of all arthropods likely had one pair of uniramous (unbranched) antenna-like structures, followed by one or more pairs of biramous (having two major branches) leg-like structures, as seen in some modern crustaceans and fossil trilobites. Except for the chelicerates and proturans, which have none, all non-crustacean arthropods have a single pair of antennae.
  • 2.2K
  • 25 Oct 2022
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