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Topic Review
Polypropylene Extrusion Molding Production Quality
Polypropylene is derived from the reaction of petrochemical propylene gas with a density of 0.89–0.94 g/cm3. It is a lightweight plastic material with a semitransparent white color and has a lower cost than other plastic materials.
  • 1.5K
  • 02 Jun 2022
Topic Review
Horror Vacui
In physics, horror vacui, or plenism (/ˈpliːnɪzəm/), commonly stated as "nature abhors a vacuum", is a postulate attributed to Aristotle, who articulated a belief, later criticized by the atomism of Epicurus and Lucretius, that nature contains no vacuums because the denser surrounding material continuum would immediately fill the rarity of an incipient void. He also argued against the void in a more abstract sense (as "separable"), for example, that by definition a void, itself, is nothing, and following Plato, nothing cannot rightly be said to exist. Furthermore, insofar as it would be featureless, it could neither be encountered by the senses, nor could its supposition lend additional explanatory power. Hero of Alexandria challenged the theory in the first century CE, but his attempts to create an artificial vacuum failed. The theory was debated in the context of 17th-century fluid mechanics, by Thomas Hobbes and Robert Boyle, among others, and through the early 18th century by Sir Isaac Newton and Gottfried Leibniz.
  • 1.5K
  • 08 Oct 2022
Topic Review
IT Baseline Protection Catalogs
The IT Baseline Protection Catalogs, or IT-Grundschutz-Kataloge, ("IT Baseline Protection Manual" before 2005) are a collection of documents from the Germany Federal Office for Security in Information Technology (BSI) that provide useful information for detecting weaknesses and combating attacks in the information technology (IT) environment (IT cluster). The collection encompasses over 3000 pages, including the introduction and catalogs. It serves as the basis for the IT baseline protection certification of an enterprise.
  • 1.5K
  • 31 Oct 2022
Biography
Laurence Hurst
Laurence Daniel Hurst (born 1965)[1] FMedSci FRS[2] is a Professor of Evolutionary Genetics in the Department of Biology and Biochemistry at the University of Bath and the director of the Milner Centre for Evolution.[3][4] Hurst was educated at Truro School[1] and completed his Bachelor of Arts in Natural Sciences (Zoology) at Churchill College, Cambridge, in 1987.[5] After a year at Harvard
  • 1.5K
  • 25 Nov 2022
Biography
François Turrettini
François Turrettini (17 October 1623 – 28 September 1687; also known as Francis Turretin) was a Genevan-Italian Reformed scholastic theologian.[1] Turrettini is especially known as a zealous opponent of the moderate Calvinist theology of the Academy of Saumur[2] (embodied by Moise Amyraut and called Amyraldianism). He was an earnest defender of the Calvinistic orthodoxy represented by the Sy
  • 1.5K
  • 16 Dec 2022
Topic Review
Analysis of Hydrocarbons from Waste Plastic
Ecosystem destruction is one of today’s significant challenges due to fast industrialisation and an increasing population. It takes several years for solid trash, such as plastic bottles and super-market bags, to decompose in nature. In addition, plastic disposal techniques such as landfilling, reuse, and incineration pose significant threats to human health and the environment.
  • 1.5K
  • 27 Dec 2022
Topic Review
Community Resilience, Adaptive Resilience and Transformative Resilience
Resilience of human systems has increasingly gained ground as both a targeted process of societal development and as a research topic in its own right. As resilience often transcends both the natural and social sciences, it has become a basis for decision-making in studies examining the complex interactions between society, land use management, and policy. While a large body of literature exists on community resilience, there are still significant gaps in knowledge and an imminent need for further research, especially social sciences research.
  • 1.5K
  • 08 Nov 2023
Topic Review
Lightning Strike Damage Assessments of Composites
Lightning strike events pose significant challenges to the structural integrity and performance of composite materials, particularly in aerospace, wind turbine blade, and infrastructure applications. 
  • 1.5K
  • 07 Feb 2024
Topic Review
Conservation-Compatible Retrofit Solutions
Historic, listed, or unlisted, buildings account for 30% of the European building stock. Since they are complex systems of cultural, architectural, and identity value, they need particular attention to ensure that they are preserved, used, and managed over time in a sustainable way. This implies a demand for retrofit solutions able to improve indoor thermal conditions while reducing the use of energy sources and preserving the heritage significance. Often, however, the choice and implementation of retrofit solutions in historic buildings is limited by socio-technical barriers (regulations, lack of knowledge on the hygrothermal behaviour of built heritage, economic viability, etc.). 
  • 1.5K
  • 24 Nov 2021
Topic Review
Epicardial Thoracoscopic Ablation
In this study we evaluated atrial fibrillation (AF) recurrence and Sarcoplasmic Endoplasmic Reticulum Calcium ATPase (SERCA) levels in patients treated by epicardial thoracoscopic ablation for persistent AF. This was a prospective, multicenter, observational study to recruit patients with persistent AF receiving an epicardial thoracoscopic pulmonary vein isolation. About 27 patients, responders (n = 15) did not present AF recurrence after epicardial ablation at one-year follow-up; these patients displayed a marked remodeling of the left atrium, with a significant reduction of inflammatory cytokines, B type natriuretic peptide (BNP), and increased levels of SERCA compared to baseline and to non responders (p < 0.05). Furthermore, mean AF duration (Heart rate (HR) 1.235 (1.037-1.471), p < 0.05), Left atrium volume (LAV) (HR 1.755 (1.126-2.738), p < 0.05), BNP (HR 1.945 (1.895-1.999), p < 0.05), and SERCA (HR 1.763 (1.167-2.663), p < 0.05) were predictive of AF recurrence. Therefore, our data indicate for the first time that baseline values of SERCA in patients with persistent AF might be predictive of failure to epicardial ablative approach. Intriguingly, epicardial ablation was associated with increased levels of SERCA in responders. Thus, SERCA might be an innovative therapeutic target to improve the response to epicardial ablative treatments.
  • 1.5K
  • 28 Oct 2020
Topic Review
Bioluminescence Imaging
Bioluminescence imaging (BLI) is based on the catalytic activity of luciferase enzymes, which oxidize the substrate called luciferin to generate an excited-state molecule that emits bioluminescence.
  • 1.5K
  • 12 Oct 2020
Topic Review
Satellite DNA of primate genome
Satellite DNA (satDNA) is defined as highly repetitive DNA consisting of short sequences tandemly repeated a large number of times. Collectively known as the "satellitome", this genomic component offers exciting evolutionary insights into aspects of primate genome biology that raise new questions and challenge existing paradigms. 
  • 1.5K
  • 25 Jan 2021
Topic Review
TOR–Auxin Connection Upstream Root-Hair Growth
Plant growth and productivity are orchestrated by a network of signaling cascades involved in balancing responses to perceived environmental changes with resource availability. Vascular plants are divided into the shoot, an aboveground organ where sugar is synthesized, and the underground located root. Continuous growth requires the generation of energy in the form of carbohydrates in the leaves upon photosynthesis and uptake of nutrients and water through root hairs. Root hair outgrowth depends on the overall condition of the plant and its energy level must be high enough to maintain root growth. TARGET OF RAPAMYCIN (TOR)-mediated signaling cascades serve as a hub to evaluate which resources are needed to respond to external stimuli and which are available to maintain proper plant growth. Root hair formation further requires appropriate distribution of the phytohormone auxin, which primes root hair cell fate and triggers root hair elongation. While TOR activity partially depends on auxin signaling, auxin distribution to the root tip and the redistribution towards the root hair zone are, on the other hand, dependent on TOR activity. Together, both signaling cascades are interwoven to orchestrate proper root hair outgrowth to ensure efficient plant nutrition. 
  • 1.5K
  • 02 Feb 2021
Topic Review
Vaccinium Species: Composition and Activity
The genus Vaccinium L. (Ericaceae) includes more than 450 species, which grow mainly in cooler areas of the northern hemisphere. Vaccinium species have been used in the traditional medicine of different cultures and the berries are widely consumed as food. Indeed, Vaccinium supplements-based herbal medicine and functional food, mainly from V. myrtillus and V. macrocarpon, are used in Europe and North America. Biological studies support traditional uses since for many of Vaccinium components important biological functions have been described, including antioxidant, antitumor, anti-inflammatory, antidiabetic, and endothelium protective activities. Vaccinium components, such as polyphenols, anthocyanins, and flavonoids, are widely recognized as modulators of cellular pathways involved in pathological conditions, thus indicating that Vaccinium may be an important source of bioactive molecules. 
  • 1.5K
  • 14 Jul 2021
Topic Review
Perceived Value’ Predictive Relationship
Ecotourism development is a distinct market phenomenon and a necessary form of sustainable tourism, which grows three times faster than tourism in general. Ecotourism’s rising popularity worldwide has encouraged tourist destinations to receive more and more tourists who like contact with nature and are willing to comply with the protection standards of the natural area chosen. 
  • 1.5K
  • 28 Jul 2021
Topic Review
Ribosome Interactions with SARS-CoV-2 and COVID-19 mRNA Vaccine
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is the causing pathogen of the unprecedented global Coronavirus Disease 19 (COVID-19) pandemic. Upon infection, the virus manipulates host cellular machinery and ribosomes to synthesize its own proteins for successful replication and to facilitate further infection. SARS-CoV-2 executes a multi-faceted hijacking of the host mRNA translation and cellular protein synthesis. Viral nonstructural proteins (NSPs) interact with a range of different ribosomal states and interfere with mRNA translation. Concurrent mutations on NSPs and spike proteins contribute to the epidemiological success of variants of concern (VOCs). The interactions between ribosomes and SARS-CoV-2 represent attractive targets for the development of antiviral therapeutics and vaccines.
  • 1.5K
  • 18 Feb 2022
Topic Review
Rural–Urban Industry Linkages
Rural–urban linkages refer to the goods, people, and money transfers between rural and urban places, and have long been a focus for economic development researchers and practitioners alike. Urban places typically have higher incomes and more diverse market segments, making greater rural–urban market integration a potentially lucrative business and rural development strategy. Indeed, urban-adjacent rural communities often have comparative advantages in the production of food, energy, tourism, and other rural goods and services desired by urban consumers. Thus, identifying how these interdependent economic flows affect the economic prosperity of rural places may better inform rural development policies and strategies.
  • 1.5K
  • 14 Mar 2022
Topic Review
Phosphatidylserine
Cancer is among the leading causes of death worldwide. In recent years, many cancer-associated biomarkers have been identified that are used for cancer diagnosis, prognosis, screening, and early detection, as well as for predicting and monitoring carcinogenesis and therapeutic effectiveness. Phosphatidylserine (PS) is a negatively charged phospholipid which is predominantly located in the inner leaflet of the cell membrane. In many cancer cells, PS externalizes to the outer cell membrane, a process regulated by calcium-dependent flippases and scramblases. Saposin C coupled with dioleoylphosphatidylserine (SapC-DOPS) nanovesicle (BXQ-350) and bavituximab, (Tarvacin, human–mouse chimeric monoclonal antibodies) are cell surface PS-targeting drugs being tested in clinical trial for treating a variety of cancers. Additionally, a number of other PS-selective agents have been used to trigger cytotoxicity in tumor-associated endothelial cells or cancer cells in pre-clinical studies.
  • 1.5K
  • 25 May 2022
Topic Review
β-Cyclocitral Marked as Bioactive Compound in Plants
β-cyclocitral (βCC), a main apocarotenoid of β-carotene, increases plants’ resistance against stresses. It has recently appeared as a novel bioactive composite in a variety of organisms from plants to animals. In plants, βCC marked as stress signals that accrue under adverse ecological conditions. βCC regulates nuclear gene expression through several signaling pathways, leading to stress tolerance. 
  • 1.5K
  • 01 Nov 2022
Topic Review
Goonda
"Goonda" is a term in Indian English, Pakistani English, and Bangladeshi English for a hired thug. It is both a colloquial term and defined and used in laws, generally referred to as Goonda Acts.
  • 1.5K
  • 10 Nov 2022
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