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Topic Review
Xanthone Glucosides
Xanthones are secondary metabolites found in plants, fungi, lichens, and bacteria froma variety of families and genera, with the majority found in the Gentianaceae, Polygalaceae, and Clusiaceae. They have a diverse range of bioactivities, including anti-oxidant, anti-bacterial, antimalarial, anti-tuberculosis, and cytotoxic properties. Xanthone glucosides are a significant branch of xanthones. After glycosylation, xanthones may have improved characteristics (such as solubility and pharmacological activity). Currently, no critical review of xanthone glucosides has been published.
  • 1.6K
  • 25 Oct 2021
Topic Review
Wind Speed Analysis of Hurricane Sandy
The database of the HWind project sponsored by the National Oceanic and Atmospheric Administration (NOAA) for hurricanes between 1994 and 2013 is analysed. Moreover, the wind speed of Hurricane Sandy is studied.
  • 1.6K
  • 18 Nov 2021
Topic Review
Exercise Interventions in Cancer-Related Cachexia
Cancer-related cachexia is a complex multifactorial phenomenon in which systemic inflammation plays a key role in the development and maintenance of the symptomatology. Pharmacological interventions seem to produce a positive effect on inflammatory state and cachexia. Nutritional interventions are focused on a high-energy diet with high-density foods and the supplementation with antioxidants, while physical activity is focused on strength-based training. The implementation of multidisciplinary non-pharmacological interventions in cancer-related cachexia could be an important tool to improve traditional treatments and improve patients’ quality of life.
  • 1.6K
  • 14 Jun 2022
Topic Review
Lee-Style T'ai Chi Ch'uan
The Lee style of t'ai chi ch'uan (李氏太極拳) is closely related to a range of disciplines of Taoist Arts taught within the Lee style including Qigong, Tao Yin, Ch'ang Ming, Traditional Chinese Medicine, Taoist alchemy, Feng Shou Kung Fu, and weapons practice. According to practitioners, it was first brought to the West in the 1930s by Chan Kam Lee and was subsequently popularized by Chee Soo who was the President of the International Taoist Society from 1958 until his death in 1994. The Lee style of t'ai chi ch'uan comprises two forms known as 'the dance' or Tiào wǔ 跳舞, and 'the form'. Other exercises include I Fu Shou or 'sticky hands', Whirling Hands, Whirling Arms, and various qi and Li development exercises. Lee style t'ai chi is related to Martial Arts training, and there are five distinct areas of development that comprise the whole Art:
  • 1.6K
  • 12 Oct 2022
Topic Review
Stazione Zoologica
The Stazione Zoologica Anton Dohrn is a research institute in Naples, Italy, devoted to basic research in biology. Research is largely interdisciplinary involving the fields of evolution, biochemistry, molecular biology, neurobiology, cell biology, biological oceanography, marine botany, molecular plant biology, benthic ecology, and ecophysiology. Founded in 1872 as a private concern by Anton Dohrn, in 1982 the Stazione Zoologica came under the supervision and control of the Ministero dell'Università e della Ricerca Scientifica e Tecnologica (Ministry of Universities and Scientific and Technological Research) as a National Institute.
  • 1.6K
  • 26 Oct 2022
Topic Review
Aflatoxins in Cereals and Cereal-Based Products
Cereals and cereal-based products are primary sources of nutrition across the world. However, contamination of these foods with aflatoxins (AFs), secondary metabolites produced by several fungal species, has raised serious concerns. AF generation in innate substrates is influenced by several parameters, including the substrate type, fungus species, moisture content, minerals, humidity, temperature, and physical injury to the kernels. Consumption of AF-contaminated cereals and cereal-based products can lead to both acute and chronic health issues related to physical and mental maturity, reproduction, and the nervous system. Therefore, the precise detection methods, detoxification, and management strategies of AFs in cereal and cereal-based products are crucial for food safety as well as consumer health.
  • 1.6K
  • 03 Nov 2022
Biography
Arthur W. Conway
Arthur William Conway FRS[1] (2 October 1875 – 11 July 1950) was a distinguished Irish mathematician and mathematical physicist who wrote one of the first books on relativity and co-edited two volumes of William Rowan Hamilton's collected works. He also served as President of University College Dublin between 1940 and 1947.[2] Memorial plaque in Wexford town. https://handwiki.org/wi
  • 1.6K
  • 15 Dec 2022
Topic Review
Huntingtin and Other Neurodegeneration-Associated Proteins in Intracellular Pathologies
Neurodegenerative diseases are currently incurable. Numerous experimental data accumulated over the past fifty years have brought us closer to understanding the molecular and cell mechanisms responsible for their development. It is known that the basis of neurodegenerations are proteinopathies, disorders in the structure and function of various proteins that lead to their aggregation and toxic effects on cells. The most common neurodegenerative proteinopathies are amyloidosis (amyloid extracellular plaques in AD), tauopathy (various dementias), α-synucleopathy (Lowy bodies in PD), prionopathy, and TDP-43 proteinopathy (in amyotrophic lateral sclerosis (ALS)).
  • 1.6K
  • 26 Dec 2022
Topic Review
SOFA Score
In 2016, the SOFA score was proposed as the main evaluation system for diagnosis in the definition of sepsis 3.0, and the SOFA score has become a new research focus in sepsis. Some people are skeptical about diagnosing sepsis using the SOFA score. Experts and scholars from different regions have proposed different, modified versions of SOFA score to make up for the related problems with the use of the SOFA score in the diagnosis of sepsis. 
  • 1.6K
  • 30 May 2023
Topic Review
Green Innovation in State-Owned Enterprises
Green innovation is an advancement in environmental sustainability that has a positive impact on both economic development and the environment. For this reason, governments and societies put growing attention to green innovation. Green innovation has a positive impact on enterprises; however, there is no consensus for what concern the efficiency of green innovation in state-owned enterprises. The latter is relevant because of the predominant position of state-owned enterprises in high-polluting and energy industries, and their connection with governments and their policies.
  • 1.6K
  • 17 Jul 2023
Topic Review
Ethical Approach in Echinoderms
The majority of ethical and welfare approaches in animal research have primarily focused on vertebrates. Echinoderms are a phylum of marine invertebrates. They are often key, long-living species that shape and maintain the status of many marine ecosystems, inhabiting a wide range of ecological niches from the abyssal depths of the oceans to the intertidal zone. Progress has been made toward developing an ethical framework for invertebrates, such as crustaceans, echinoderms, and cephalopods.
  • 1.6K
  • 15 Nov 2023
Topic Review
MoS2 Nanomaterials as Lubricant Additives
Improving the lubricating properties of base oils through additives is a crucial objective of tribological research, as it helps to reduce friction and wear of materials. Molybdenum disulfide (MoS2) is a 2D nanomaterial with excellent tribological properties that is often used as a lubricant additive. Several studies have been conducted on the preparation and utilization of MoS2 and its nanocomposites as lubricant additives. 
  • 1.6K
  • 25 Dec 2023
Topic Review
Cell Autonomous Mechanisms in Astrocytes in Neurodegenerative Diseases
Neurodegenerative disorders like Alzheimer’s disease (AD), Parkinson’s disease (PD), frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS) affect millions of people worldwide, and as the average human lifespan increases, similarly grows the number of patients. Cognitive and motoric decline has been explained by the very apparent deterioration of neurons in various regions of the brain and spinal cord. However, more studies show that disease progression is greatly influenced by the vast population of glial cells. Astrocytes are traditionally considered star-shaped cells on which neurons rely heavily for their optimal homeostasis and survival. Increasing amounts of evidence depict how astrocytes lose their supportive functions while simultaneously gaining toxic properties during neurodegeneration. 
  • 1.6K
  • 12 Mar 2024
Topic Review
Two-Phase Fermentation Systems for Microbial Production of Terpenes
Microbial cell factories, renowned for their economic and environmental benefits, have emerged as a key trend in academic and industrial areas, particularly in the fermentation of natural compounds. Among these, plant-derived terpenes stand out as a significant class of bioactive natural products. The large-scale production of such terpenes, exemplified by artemisinic acid—a crucial precursor to artemisinin—is now feasible through microbial cell factories. In the fermentation of terpenes, two-phase fermentation technology has been widely applied due to its unique advantages. It facilitates in situ product extraction or adsorption, effectively mitigating the detrimental impact of product accumulation on microbial cells, thereby significantly bolstering the efficiency of microbial production of plant-derived terpenes. 
  • 1.6K
  • 02 Apr 2024
Topic Review
Inappropriate Secretion of Thyroid-Stimulating Hormone
The term “inappropriate secretion of thyroid-stimulating hormone; IST” was proposed by Gershengorn and Weintraub in 1975. In a subsequent report, IST was described as a condition characterized by elevated serum levels of immunoreactive thyroid-stimulating hormone (TSH) in the presence of elevated free thyroid hormone concentrations. Similarly, the term "syndrome of IST (SITSH)" is widely used in Japan to refer to a closely related condition; however, unlike that for IST, an elevated serum free triiodothyronine concentration is not a requisite criterion for SITSH diagnosis. IST or SITSH is an important indicator of resistance to thyroid hormone β (RTHβ) caused by germline mutations in genes encoding thyroid hormone receptor β (TRβ) and TSH-secreting pituitary adenoma.
  • 1.6K
  • 12 Aug 2021
Topic Review
Membrane Fusion
Membrane fusion is a universal reaction that mediates a myriad of biological events, such as fertilization, organ and tissue growth, cancer metastasis, and multi-nucleated giant cell formation during an immune response .
  • 1.6K
  • 06 Feb 2021
Topic Review
Mechanical Heart Valve Patients with Intracranial Hemorrhage
The management of an intracranial hemorrhage in patients receiving anticoagulant therapy presents a significant challenge for medical professionals. Anticoagulant treatment is intended to prevent blood clotting, but it can worsen active brain bleeds. Despite this risk, avoiding the prothrombotic state caused by mechanical heart valves remains crucial. 
  • 1.6K
  • 17 May 2023
Topic Review
Quetiapine-Related Deaths
Quetiapine is a second-generation antipsychotic drug available for two and half decades. Due to increased misuse, prescription outside the approved indications, and availability on the black market, it is being encountered in medicolegal autopsies more frequently. For instance, it has been linked to increased mortality rates, most likely due to its adverse effects on the cardiovascular system. 
  • 1.6K
  • 10 Jan 2024
Topic Review
Psychosocial Interventions for Dyslexic Adults
       Enabling dyslexic adults’ participation in the work environment is vital to unleashing their potential and essential to make the workplace more inclusive. This can be supported through psychosocial interventions that target a set of positive self-evaluations commonly linked to resiliency and an individual’s sense of ability to control and impact the environment in a successful manner, including coping strategies and self-management. A systematic review has been carried out to map and integrate the understanding of interventions in this field. It reveals that interventions can be useful in enhancing psychological resources among dyslexic adults. Still, it also highlights the critical gap in this literature, where knowledge in this field remains mostly based on common sense rather than on evidence from research. Given the high incidence of dyslexia, its health consequences and high financial costs, this is particularly problematic and emphasizes the need for research designs to evaluate interventions’ effectiveness on the improvement of psychological resources and employment opportunities. More intervention studies are needed to understand the effects of initiatives on dyslexic adults’ psychological resources and well-being, employing validated and reliable scales for outcome assessment.
  • 1.6K
  • 12 Oct 2020
Topic Review
Invasive Algae Species
Invasive alien species (IAS), also known as exotic or non-native species, are plants or animals that have been introduced, intentionally or not, into regions where it is not usual to find them.
  • 1.6K
  • 21 Apr 2021
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